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Abbreviation : ETA
Long Form : endothelin A
No. Year Title Co-occurring Abbreviation
2019 Afferent arteriole responsiveness to endothelin receptor activation: does sex matter? ET-1, ETB
2019 Endothelin Receptor Antagonism Improves Lipid Profiles and Lowers PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) in Patients With Chronic Kidney Disease. CKD
2018 Differential somatostatin, CXCR4 chemokine and endothelin A receptor expression in WHO grade I-IV astrocytic brain tumors. SST
2018 Novel treatment avenues for uterine leiomyoma: a new implication for endothelin? CYR61, ET-1, MSMCs, SMCs
2018 Prevention of the progression of renal injury in diabetic rodent models with preexisting renal disease with chronic endothelin A receptor blockade. DN, ET, MAP, STZ-SS, T2DN
2017 Enhanced photothermal therapy of biomimetic polypyrrole nanoparticles through improving blood flow perfusion. RBC
2017 Influence of Mechanical Circulatory Support on Endothelin Receptor Expression in Human Left Ventricular Myocardium from Patients with Dilated Cardiomyopathy (DCM). DCM, ETR, VAD
2017 Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma. ET-1, ETB, IOP, RGCs
2016 Endothelium-Dependent Contractions: Prostacyclin and Endothelin-1, Partners in Crime? EDCF, ETB, TP
10  2016 From bosentan (Tracleer) to macitentan (Opsumit): The medicinal chemistry perspective. ERAs, ETB, PAH
11  2016 Neurobiology of opioid withdrawal: Role of the endothelin system. ---
12  2016 Ovarian hormones modulate endothelin A and B receptor expression. ---
13  2016 Role of endothelin in microvascular dysfunction following percutaneous coronary intervention for non-ST elevation acute coronary syndromes: a single-centre randomised controlled trial. APV, ET-1, NSTACS, PCI
14  2016 The effect of endothelin A and B receptor blockade on cutaneous vascular and sweating responses in young men during and following exercise in the heat. CVC, ETB
15  2015 A Meta-Analysis and Indirect Comparison of Endothelin A Receptor Antagonist for Castration-Resistant Prostate Cancer. AEs, CRPC, OS, PFS, RCTs, TTP
16  2015 Bupivacaine inhibits endothelin-1-evoked increases in intracellular calcium in model sensory neurons. ET-1
17  2015 Endothelin A receptor antagonist, atrasentan, attenuates renal and cardiac dysfunction in Dahl salt-hypertensive rats in a blood pressure independent manner. CKD, CVD, DSS, HS, MAP, ND, RAS
18  2015 Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet. BP, HanSD, TGRs
19  2015 Endothelin Blockade in Diabetic Kidney Disease. DKD, ET-1
20  2015 Endothelin ETA receptor antagonist reverses naloxone-precipitated opioid withdrawal in mice. NGF
21  2015 Macitentan: An important addition to the treatment of pulmonary arterial hypertension. ET-1, ETB, FDA, PAH
22  2015 Selective astrocytic endothelin-1 overexpression contributes to dementia associated with ischemic stroke by exaggerating astrocyte-derived amyloid secretion. BBB, ET-1, ETB, tMCAO
23  2014 Combined endothelin a blockade and chlorthalidone treatment in a rat model of metabolic syndrome. ABT, CLTD, MAP
24  2014 Cyclopiazonic acid alters serotonin-induced responses in rat thoracic aorta. CPA, ET-1
25  2014 Disparate effects of single endothelin-A and -B receptor blocker therapy on the progression of renal injury in advanced renovascular disease. ---
26  2014 Endothelin-1 stimulates proinflammatory cytokine expression in human periodontal ligament cells via mitogen-activated protein kinase pathway. ET-1, hPDL, IL, MAPKs, mRNA, TNF
27  2013 Endothelin antagonists for diabetic and non-diabetic chronic kidney disease. CKD
28  2013 Endothelin-1 downregulates angiotensin-converting enzyme-2 expression in human bronchial epithelial cells. ACE2, COPD, ET-1, HBEpCs, MAPK, RAS
29  2013 Endothelin-1 downregulates Mas receptor expression in human cardiomyocytes. Ang, ET-1, MAPK, RAS
30  2013 Long-term endothelin receptor antagonism attenuates coronary plaque progression in patients with early atherosclerosis. IVUS, PAV
31  2013 Nitric oxide and the A and B of endothelin of sodium homeostasis. ET-1, ETB, NOS1
32  2013 Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial. IPF
33  2012 Non-endothelial cell endothelin-B receptors limit neointima formation following vascular injury. ET-1, ETB
34  2011 Decreased contractile response to endothelin-1 of peripheral microvasculature from diabetic patients. ET-1, ET-B, PKCalpha
35  2011 Endothelin B receptor contribution to peripheral microvascular function in women with polycystic ovary syndrome. ET-B, PCOS, SkBF
36  2011 Hypoperfusion in the acute phase of subarachnoid hemorrhage. ADC, CBF, DWI, HT, ICP, LDF, MD, MRS, SAH, Xe-CT
37  2011 Pharmacokinetics and tolerability of zibotentan (ZD4054) in subjects with hepatic or renal impairment: two open-label comparative studies. ---
38  2010 Darusentan is a potent inhibitor of endothelin signaling and function in both large and small arteries. ERAs, RAVSMs
39  2010 Effects of cardiopulmonary bypass on endothelin-1-induced contraction and signaling in human skeletal muscle microcirculation. CPB, ET-1, ET-B, PKCalpha
40  2010 Endothelin-1-induced contractile responses of human coronary arterioles via endothelin-A receptors and PKC-alpha signaling pathways. CP, CPB, ET-1, ET-B, PKCalpha
41  2010 Endothelin-A receptor antagonism attenuates carcinoma-induced pain through opioids in mice. SCC
42  2010 The endothelin axis influences enteric glia cell functions. EGC, ET-1, ETB, GFAP, IL-1 beta, TNF-alpha
43  2010 The role of endothelin-1 and its receptors in optic nerve head astrocyte proliferation. ET-1, ETB, GFAP, MBP, ONHA
44  2009 Biology of endothelin receptors in the collecting duct. ET, ETB, PGE2
45  2009 Endothelin receptor antagonists in preclinical models of pulmonary hypertension. ET, ET-1, ETB, PH
46  2009 Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer. ETB, NSCLC
47  2009 MMP-2 and MMP-9 alteration in response to collaring in rabbits: the effects of endothelin receptor antagonism. MMPs, s.c
48  2009 Preclinical anticancer activity of the specific endothelin A receptor antagonist ZD4054. ETB
49  2008 Examination of mRNA expression in rat hearts and lungs for analysis of effects of exposure to concentrated ambient particles on cardiovascular function. CVDs, FPM, HO-1
50  2008 In vivo cerebrovascular effects of cocaine- and amphetamine-regulated transcript (CART) peptide. CART, CARTp, HPA
51  2008 Intrauterine infusion of BQ-610, an endothelin type A receptor antagonist, delays luteolysis in dairy heifers. ET-1, PGF2 alpha
52  2008 Low NaCl intake elevates renal medullary endothelin-1 and endothelin A (ETA) receptor mRNA but not the sensitivity of renal Na+ excretion to ETA receptor blockade in rats. ET-1, FENa
53  2008 Synthesis of platelet-activating factor and its receptor expression in Kupffer cells in rat carbon tetrachloride-induced cirrhosis. ETB, PAF
54  2008 [The relationship between endothelin receptors and chronic venous insufficiency of lower extremities]. CVI, ET-1, ETB, S6c
55  2007 Selective endothelin-A receptor inhibition after cardiac surgery: a safety and feasibility study. CPB, PAP
56  2006 Cardioprotective effects of atrasentan, an endothelin-A receptor antagonist, but not of nitric oxide in diabetic mice with myocyte-specific overexpression of endothelial nitric oxide synthase. eNOS, ET-1, NO, STZ
57  2006 Selective endothelin a (ETA) receptor antagonist (BQ-123) reduces both myocardial infarct size and oxidant injury. BP, CAT, ET, HR, I/R, MI/R, NO, SOD
58  2005 Characterization of the in vitro atropisomeric interconversion rates of an endothelin A antagonist by enantioselective liquid chromatography. ---
59  2005 Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized, double-blind, placebo-controlled, multicenter phase IIa study. SAH
60  2005 Endothelin A antagonist LU-135252 and trandolapril in the treatment of the Cohen-Rosenthal diabetic hypertensive rat. ACE, CRDH, NIDDM, SBP
61  2005 Role of protein kinase C on the alteration of retinal endothelin-1 in streptozotocin-induced diabetic rats. ET-1, ET-3, ET-B, PKC, STZ
62  2004 Central endothelin-B receptor stimulation does not affect morphine analgesia in rats. i.c.v
63  2004 Comparison of endothelin-A and endothelin-B receptor distribution visualized by radioligand binding versus immunocytochemical localization using subtype selective antisera. ETB
64  2004 Differential regulation of ET(A) and ET(B) in the renal tissue of rats with compensated and decompensated heart failure. CHF, ET-1, ETB
65  2004 Effect of angiotensin II and endothelin-1 receptor blockade on the haemodynamic and hormonal changes after acute blood loss and after retransfusion in conscious dogs. AT1, MAP
66  2004 Effects of endothelin-1 eyedrops on the retina in rats. ETB
67  2004 Effects of ET(A) and ET(B) receptor blockade on post-ischemic cardiac dysfunction and norepinephrine overflow in isolated rat hearts. ETB
68  2004 Effects of systemic endothelin A receptor antagonism in various vascular beds in men: in vivo interactions of the major blood pressure-regulating systems and associations with the GNB3 C825T polymorphism. Ang II, ET-1, GNB3
69  2004 Endothelin A receptor antagonism and angiotensin-converting enzyme inhibition are synergistic via an endothelin B receptor-mediated and nitric oxide-dependent mechanism. ACE, COX, NO
70  2004 Endothelin A receptor blockade does not alter PSA secretion in prostate cancer cell lines. ---
71  2004 Endothelin receptor pharmacology and function in the mouse: comparison with rat and man. ET-1
72  2004 Fluorescence resonance energy transfer analysis reveals the existence of endothelin-A and endothelin-B receptor homodimers. ETB
73  2004 Impaired response of the denervated kidney to endothelin receptor blockade in normotensive and spontaneously hypertensive rats. BRD, ET, ETB, GFR, RBF, WKY
74  2004 Pharmacological characterization of YM598, a selective endothelin-A receptor antagonist. ETB
75  2004 Real-time polymerase chain reaction quantification of gene expression levels of murine endothelin-A and endothelin-B receptors: gene expression profiles by the standard curve method. ETB
76  2004 Remote trauma sensitizes hepatic microcirculation to endothelin via caveolin inhibition of eNOS activity. Cav-1, Ds, ET-1, ETB
77  2004 YM598, an orally active ET(A) receptor antagonist, ameliorates the progression of cardiopulmonary changes and both-side heart failure in rats with cor pulmonale and myocardial infarction. CHF
78  2003 Effects of hypoxia on endothelin-1 sensitivity in the corpus cavernosum. CC, ET-1, ETB, hfPECs, ROK
79  2003 Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling. ICAM-1, NADPH
80  2003 Endothelin-1 and vascular tone in subjects with atherogenic risk factors. ET-1, FBF
81  2003 Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats. ET-1, ETB, L-NAME, MBF, NO
82  2003 Impact of the endothelin-A receptor antagonist BQ 610 on microcirculation in global cerebral ischemia and reperfusion. ---
83  2003 Increased gene expression and production of murine endothelin receptors after birth. ET, ET-B
84  2003 Mechanisms of osteoblastic metastases: role of endothelin-1. ET-1
85  2002 Collagen accumulation after myocardial infarction: effects of ETA receptor blockade and implications for early remodeling. LV, MI
86  2002 Endothelin-1 is a potent stimulator of alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells. ECM, ET, GN, MC, MMP-2
87  2002 Endothelin-a receptor antagonist treatment improves the periosteal microcirculation after hindlimb ischemia and reperfusion in the rat. ---
88  2002 Endothelin-A receptor blockade prevents left ventricular hypertrophy and dysfunction in salt-sensitive experimental hypertension. ANF, DOCA, LV, LVH, SR
89  2002 Haemodynamic and hormonal changes during haemorrhage in conscious dogs treated with an endothelin-A receptor antagonist. ---
90  2002 Involvement of endogenous endothelin-1 in exercise-induced redistribution of tissue blood flow: an endothelin receptor antagonist reduces the redistribution. ET-1
91  2002 Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein. ACh, SNP, Tg, VC, VD
92  2002 S-0139 (Shionogi). GSK
93  2001 A polymorphism in the endothelin-A receptor gene predicts survival in patients with idiopathic dilated cardiomyopathy. ETB
94  2001 Endothelin-1 activates ET(A) receptors to increase intracellular calcium in model sensory neurons. ET-1
95  2001 Norepinephrine-induced aortic hyperplasia and extracellular matrix deposition are endothelin-dependent. ---
96  2001 Sitaxsentan (ICOS-Texas Biotechnology). CHF
97  2001 Studies on coronary arteriopathy in dogs following administration of CI-1020, an endothelin A receptor antagonist. ET-1, i.v
98  2001 Systemic ETA receptor antagonism with BQ-123 blocks ET-1 induced forearm vasoconstriction and decreases peripheral vascular resistance in healthy men. ET-1
99  2000 Effects of endothelin or angiotensin II receptor blockade on diabetes in the transgenic (mRen-2)27 rat. Ang II, AT1, ET, GFR, SBP, TGF-beta1
100  2000 Endothelin modulation of choroidal blood flow in the rabbit. ET, ET-1, ETB, IOP, MAP, NO