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Abbreviation : ETA
Long Form : exotoxin A
No. Year Title Co-occurring Abbreviation
2018 Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update. EpCAM
2018 Elimination of factor VIII-specific B cells by immunotoxins composed of a single factor VIII domain fused to Pseudomonas exotoxin A. ASC, FVIII, hC2-ETA
2018 Neutralization of Pseudomonas auruginosa Exotoxin A by human neutrophil peptide 1. HNP1
2018 Spectrophotometric, colorimetric and visually detection of Pseudomonas aeruginosa ETA gene based gold nanoparticles DNA probe and endonuclease enzyme. GNPs
2017 Fluorescence bio-barcode DNA assay based on gold and magnetic nanoparticles for detection of Exotoxin A gene sequence. 1pDNA, 2pDNA, bDNA-GNPs, MNPs
2017 Ligand Selectivity between the ADP-Ribosylating Toxins: An Inverse-Docking Study for Multitarget Drug Discovery. CT, DT
2015 Efficient cell-specific uptake of binding proteins into the cytoplasm through engineered modular transport systems. DARPin
2015 The novel multispecies Fc-specific Pseudomonas exotoxin A fusion protein alpha-Fc-ETA' enables screening of antibodies for immunotoxin development. ---
2014 Novel prodrug-like fusion toxin with protease-sensitive bioorthogonal PEGylation for tumor targeting. AUC, DARPins, PEG
10  2014 [Production and properties evaluation of monoclonal antibodies against Pseudomonas aeruginosa exotoxin A]. ---
11  2013 Immunotoxin-mediated targeting of claudin-4 inhibits the proliferation of cancer cells. CLDN4, CPE
12  2012 The Pseudomonas aeruginosa exotoxin A translocation domain facilitates the routing of CPP-protein cargos to the cytosol of eukaryotic cells. CPPs
13  2010 A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin. DT, EF-2
14  2010 Proteolysis of Pseudomonas exotoxin A within hepatic endosomes by cathepsins B and D produces fragments displaying in vitro ADP-ribosylating and apoptotic effects. ---
15  2009 Construction of the plasmid for expression of ETA-EGFP fusion protein under control of the cytomegalovirus promoter and its effects in HeLa cells. CMV, EGFP
16  2009 Norepinephrine represses the expression of toxA and the siderophore genes in Pseudomonas aeruginosa. ---
17  2009 Preclinical assessment of an anti-EpCAM immunotoxin: locoregional delivery provides a safer alternative to systemic administration. EpCAM, s.c
18  2009 Role of Vfr in regulating exotoxin A production by Pseudomonas aeruginosa. ---
19  2008 Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins. EGFR
20  2007 Expression of 14-3-3delta, cdc2 and cyclin B proteins related to exotoxin A-induced apoptosis in HeLa S3 cells. ---
21  2007 Regulation of the Pseudomonas aeruginosa toxA, regA and ptxR genes by the iron-starvation sigma factor PvdS under reduced levels of oxygen. A-sh, EO, M-st
22  2007 Target-specific cytotoxic activity of recombinant immunotoxin scFv(MUC1)-ETA on breast carcinoma cells and primary breast tumors. ---
23  2006 A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells. scFv
24  2005 Detection of Pseudomonas aeruginosa type III antibodies in children with tracheostomies. ---
25  2005 Early immune response to the components of the type III system of Pseudomonas aeruginosa in children with cystic fibrosis. CF
26  2005 Effect of static growth and different levels of environmental oxygen on toxA and ptxR expression in the Pseudomonas aeruginosa strain PAO1. DO
27  2005 Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry. ---
28  2005 Phase I clinical study of the recombinant antibody toxin scFv(FRP5)-ETA specific for the ErbB2/HER2 receptor in patients with advanced solid malignomas. ---
29  2005 Release of exotoxin A, peptidoglycan and endotoxin after exposure of clinical Pseudomonas aeruginosa isolates to carbapenems in vitro. ET, MICs, PG
30  2004 Comparison of HPV DNA vaccines employing intracellular targeting strategies. CRT, DCs, HPV-16, HSP70
31  2004 Early detection of Pseudomonas aeruginosa--comparison of conventional versus molecular (PCR) detection directly from adult patients with cystic fibrosis (CF). CF, PA, PCR, PCR
32  2004 Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism. FADD, ssDNA
33  2003 A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity. EpCAM
34  2003 Morphological and immunological evidence of a unique selective production and endoplasmic reticular accumulation of interleukin-1alpha in rat peritoneal macrophages induced by Pseudomonas aeruginosa exotoxin A. E-RPM, HPI, RPM
35  2003 Regulation of toxA by PtxR in Pseudomonas aeruginosa PA103. ---
36  2003 Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP-ribosylating toxins. DT
37  2002 Anti-ETA IgG neutralizes the effects of Pseudomonas aeruginosa exotoxin A. ETA-Ab
38  2002 Early mitochondrial dysfunction, superoxide anion production, and DNA degradation are associated with non-apoptotic death of human airway epithelial cells induced by Pseudomonas aeruginosa exotoxin A. ---
39  2002 Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin, Pseudomonas aeruginosa exotoxin A, and ricin. CT, ER, ERAD
40  2002 Pseudomonas aeruginosa exotoxin A and keratitis in mice. ---
41  2002 Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1. CF, IRF-1, IRF-1 KO, LPS, MIP-1alpha, PLC, TNF-alpha, WT
42  2002 Replacement of N-terminal portions of TGF-alpha with corresponding heregulin sequences affects ligand-induced receptor signaling and intoxication of tumor cells by chimeric growth-factor toxins. EGFR, HRG, TGF
43  2002 The Pseudomonas aeruginosa alternative sigma factor PvdS controls exotoxin A expression and is expressed in lung infections associated with cystic fibrosis. CF
44  2001 A catalytic loop within Pseudomonas aeruginosa exotoxin A modulates its transferase activity. ---
45  2001 Application of a fluorometric assay for characterization of the catalytic competency of a domain III fragment of Pseudomonas aeruginosa exotoxin A. ---
46  2000 Prevalence of capsular polysaccharide (CP) types of Staphylococcus aureus isolated from bovine mastitic milk and protection of S. aureus infection in mice with CP vaccine. CP
47  2000 Pseudomonas aeruginosa cystic fibrosis clinical isolates produce exotoxin A with altered ADP-ribosyltransferase activity and cytotoxicity. ADPRT, CF
48  2000 Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo. EGFR, mAbs
49  2000 Triggering the ExoS regulon of Pseudomonas aeruginosa: A GFP-reporter analysis of exoenzyme (Exo) S, ExoT and ExoU synthesis. Exo, GFP
50  1999 Effect of Pseudomonas aeruginosa exotoxin A on endotoxin-induced tumour necrosis factor production in murine lung. AMs, BALF, LPS, TNF
51  1999 Physiological characterization of Pseudomonas aeruginosa during exotoxin A synthesis: glutamate, iron limitation, and aconitase activity. ---
52  1998 Protection against exotoxin A (ETA) and Pseudomonas aeruginosa infection in mice with ETA-specific antipeptide antibodies. aa
53  1998 Proteolytic cleavage of Pseudomonas aeruginosa exotoxin A in the presence of lipid bilayers of different composition. ---
54  1997 Elevation of vacuolar pH inhibits the cytotoxic activity of furin-cleaved exotoxin A. ---
55  1997 Sequence and structural links between distant ADP-ribosyltransferase families. ADPRT, DT, LT, PT
56  1997 The adsorption of Pseudomonas aeruginosa exotoxin A to phospholipid monolayers is controlled by pH and surface potential. ---
57  1996 Exotoxin A production in Pseudomonas aeruginosa requires the iron-regulated pvdS gene encoding an alternative sigma factor. Fur
58  1996 Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environments. cs, Fur
59  1996 In vitro enzyme activation and folded stability of Pseudomonas aeruginosa exotoxin A and its C-terminal peptide. ---
60  1996 Internalization and translocation of a new chimeric protein composed of Pseudomonas aeruginosa exotoxin A and mouse dihydrofolate reductase as a model system. DHFR
61  1996 Linker insertion scanning of regA, an activator of exotoxin A production in Pseudomonas aeruginosa. aa
62  1995 Active site mutations of Pseudomonas aeruginosa exotoxin A. Analysis of the His440 residue. ---
63  1995 Biotechnological and gene therapeutic strategies in cancer treatment. CTL, ErbB-2R, mAb, TCR
64  1995 Effect of conjugation methodology, carrier protein, and adjuvants on the immune response to Staphylococcus aureus capsular polysaccharides. ADH, CP, DTd, MPL, SPDP
65  1995 Targeted inhibition of tumor-cell growth by recombinant heregulin-toxin fusion proteins. EGF, HRG
66  1994 Association between transcript levels of the Pseudomonas aeruginosa regA, regB, and toxA genes in sputa of cystic fibrosis patients. CF
67  1994 Detection of Pseudomonas aeruginosa from clinical and environmental samples by amplification of the exotoxin A gene using PCR. ---
68  1994 Evidence for the modulation of Pseudomonas aeruginosa exotoxin A-induced pore formation by membrane surface charge density. LUV, POPC, POPS
69  1994 The vfr gene product, required for Pseudomonas aeruginosa exotoxin A and protease production, belongs to the cyclic AMP receptor protein family. CAP or Crp
70  1994 ToxR (RegA)-mediated in vitro transcription of Pseudomonas aeruginosa toxA. RNAP
71  1993 A variant of exotoxin A that forms potent and specific chemically conjugated immunotoxins. ---
72  1993 In vivo production of exotoxin A and its role in endogenous Pseudomonas aeruginosa septicemia in mice. TNF
73  1992 Conformational integrity of a recombinant toxoid of Pseudomonas aeruginosa exotoxin A containing a deletion of glutamic acid-553. ---
74  1992 Expression of bacterial cytotoxin genes in mammalian target cells. CYA, PT
75  1992 Pseudomonas aeruginosa exotoxin A interaction with eucaryotic elongation factor 2. Role of the His426 residue. EF-2
76  1991 Functional analysis of exotoxin A-related protein of Pseudomonas aeruginosa lacking residues 225-412. ---
77  1991 Immunochemical analysis of Pseudomonas aeruginosa exotoxin A. Analysis of the His426 determinant. ADPRT
78  1990 Identification of functional epitopes of Pseudomonas aeruginosa exotoxin A using synthetic peptides and subclone products. ---
79  1990 Pseudomonas aeruginosa exotoxin A: alterations of biological and biochemical properties resulting from mutation of glutamic acid 553 to aspartic acid. ---
80  1990 Synthesis and immunologic properties in mice of vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides conjugated to Pseudomonas aeruginosa exotoxin A. CPS
81  1990 [The diagnostic effectiveness of erythrocyte immunoreagents made from different Pseudomonas aeruginosa antigens]. LPS, PHA
82  1989 A dipeptide insertion in domain I of exotoxin A that impairs receptor binding. ---
83  1989 Biochemical analysis of CRM 66. A nonfunctional Pseudomonas aeruginosa exotoxin A. EF-2
84  1989 Effects of eliminating a disulfide bridge within domain II of Pseudomonas aeruginosa exotoxin A. ---
85  1989 Regulation of exotoxin A synthesis in Pseudomonas aeruginosa: characterization of toxA-lacZ fusions in wild-type and mutant strains. ---
86  1989 [Erythrocyte diagnostic kits for detection of Pseudomonas aeruginosa exotoxin A]. AbED, PHA
87  1988 Amino acid sequence homology between the enzymic domains of diphtheria toxin and Pseudomonas aeruginosa exotoxin A. DT
88  1988 His-426 of the Pseudomonas aeruginosa exotoxin A is required for ADP-ribosylation of elongation factor II. ---
89  1988 Pseudomonas aeruginosa exotoxin A: effects of mutating tyrosine-470 and tyrosine-481 to phenylalanine. EF-2
90  1988 Restoration of enzymic activity and cytotoxicity of mutant, E553C, Pseudomonas aeruginosa exotoxin A by reaction with iodoacetic acid. ---
91  1988 Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue. ---
92  1987 Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin. DT
93  1987 Exotoxin A of Pseudomonas aeruginosa: active, cloned toxin is secreted into the periplasmic space of Escherichia coli. ---
94  1987 Exotoxin A of Pseudomonas aeruginosa: evidence that domain I functions in receptor binding. ---
95  1987 Exotoxin A of Pseudomonas aeruginosa: substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity. ---
96  1987 Nucleotide sequence and characterization of toxR: a gene involved in exotoxin A regulation in Pseudomonas aeruginosa. ---
97  1986 Analysis of transcription of the exotoxin A gene of Pseudomonas aeruginosa. bp
98  1986 Molecular studies of Pseudomonas exotoxin A gene. ---
99  1984 Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. ---