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Abbreviation : EnAd
Long Form : enadenotucirev
No. Year Title Co-occurring Abbreviation
2020 A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR). CEDAR, TiTE-CRM
2020 Attenuation of the Hypoxia Inducible Factor Pathway after Oncolytic Adenovirus Infection Coincides with Decreased Vessel Perfusion. HIF
2019 Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples. FRbeta, TAMs
2019 Polyvalent Diazonium Polymers Provide Efficient Protection of Oncolytic Adenovirus Enadenotucirev from Neutralizing Antibodies while Maintaining Biological Activity In Vitro and In Vivo. polyHPMA
2018 Antagonism of Glycolysis and Reductive Carboxylation of Glutamine Potentiates Activity of Oncolytic Adenoviruses in Cancer Cells. ---
2018 Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirusin murine cancer cells. ---
2017 Group B adenovirus enadenotucirev infects polarised colorectal cancer cells efficiently from the basolateral surface expected to be encountered during intravenous delivery to treat disseminated cancer. Ad5
2017 Oncolytic adenovirus expressing bispecific antibody targets T-cell cytotoxicity in cancer biopsies. BiTE
2017 Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators. ---
10  2015 Actin-resistant DNAse I Expression From Oncolytic Adenovirus Enadenotucirev Enhances Its Intratumoral Spread and Reduces Tumor Growth. aDNAse I, C-ABC, PK