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Abbreviation : FGF4
Long Form : fibroblast growth factor 4
No. Year Title Co-occurring Abbreviation
2019 Clinical Utility of Cerebrospinal Fluid Cell-Free DNA as Liquid Biopsy for Leptomeningeal Metastases in ALK-Rearranged NSCLC. ALK, CCND1, CDKN2A, CSF, FGF3, LMs, MYC, TP53
2019 Suppression of TGF-beta and ERK signaling pathways as a new strategy to provide rodent and non-rodent pluripotent stem cells. ES, LIF, SMs
2019 The Differentiation Potency of Trophoblast Stem Cells from Mouse Androgenetic Embryos. MEK, TGCs, TS
2018 Neutralizing FGF4 protein in conditioned medium of IL-21-silenced HCT116 cells restores the migratory activity of the colorectal cancer cells. IL-21
2018 O-GlcNAc on PKCzeta Inhibits the FGF4-PKCzeta-MEK-ERK1/2 Pathway via Inhibition of PKCzeta Phosphorylation in Mouse Embryonic Stem Cells. ESCs, MEK, O-GlcNAcylation
2018 Retaining mTeSR1 Medium during Hepatic Differentiation Facilitates Hepatocyte-Like Cell Survival by Decreasing Apoptosis. AFP, ALB, BMP4, DE, FOXA2, HGF, HNF4alpha, ICG, iPS, PAS, SOX17
2018 RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17alpha-ethynylestradiol. AhR, BaP, CYP 1A, FGF3, PCLS, VTG, ZP
2017 Injectable Polypeptide Thermogel as a Tissue Engineering System for Hepatogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells. HGF, PEG-l-PA, TMSCs, TUDCA
2017 Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2. EPI, Fgfr, ICM, PrE
10  2017 The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis. AB, JNK, LR, MCAM, NFAT, PCP, PLCgamma
11  2016 Cell proliferation potency is independent of FGF4 signaling in trophoblast stem cells derived from androgenetic embryos. TS
12  2016 Expression of Syncytin 1 (HERV-W), in the preimplantation human blastocyst, embryonic stem cells and trophoblast cells derived in vitro. BMP4, hESCs, ICM, qPCR
13  2016 Fibroblast growth factor 4-induced migration of porcine trophectoderm cells is mediated via the AKT cell signaling pathway. PI3K, pTr
14  2016 Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4. mTSC, PRL3D1, TGC
15  2016 Pretreatment of BMSCs with TZD solution decreases the proliferation rate of MCF‑7 cells by reducing FGF4 protein expression. BMSCs
16  2016 The oncoprotein HBXIP up-regulates FGF4 through activating transcriptional factor Sp1 to promote the migration of breast cancer cells. HBXIP
17  2016 Wnt/beta-Catenin Regulates the Activity of Epiprofin/Sp6, SHH, FGF, and BMP to Coordinate the Stages of Odontogenesis. BIO, BMP4, DKK-1, Epfn, FGF10, FGF8, Msx-1, Shh, Wnt-10b
18  2015 Cdx2 efficiently induces trophoblast stem-like cells in naive, but not primed, pluripotent stem cells. ECCs, EpiSCs, ESCs, iPSCs, TSCs
19  2015 Comparative analysis of mesenchymal stem cell and embryonic tendon progenitor cell response to embryonic tendon biochemical and mechanical factors. MSCs, TGF-beta2, TPCs
20  2015 Comparison of hepatic nuclear factor-4 expression in two- and three-dimensional culture of Wharton's jelly-derived cells exposed to hepatogenic medium. HNF4alpha, qRT-PCR, WJ-MSCs
21  2015 Generation of aminoterminally truncated, stable types of bioactive bovine and porcine fibroblast growth factor 4 in Escherichia coli. ---
22  2015 The enamel knot-like structure is eternally maintained in the apical bud of postnatal mouse incisors. CL, Shh
23  2015 The influence of fibroblast growth factor 4 on hepatogenic capacity of Wharton's jelly mesenchymal stromal cells. HGF, ICG, IGF-1, PAS, RT-PCR, WJ-MSCs
24  2014 Fibroblast growth factor 4 is required but not sufficient for the astrocyte dedifferentiation. CNS, NSPCs
25  2014 Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity. CAFs, CICs, CSCs, siRNA
26  2014 Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency. TSC
27  2014 Identification of site-specific degradation in bacterially expressed human fibroblast growth factor 4 and generation of an aminoterminally truncated, stable form. His
28  2014 Production of an aminoterminally truncated, stable type of bioactive mouse fibroblast growth factor 4 in Escherichia coli. His
29  2014 Stem cells with FGF4-bFGF fused gene enhances the expression of bFGF and improves myocardial repair in rats. BMSCs, EGFP
30  2014 The dual roles of geminin during trophoblast proliferation and differentiation. Gmnn, TGCs, TSCs
31  2014 [Effect of Yiguan Decoction on differentiation of bone marrow mesenchymal stem cells into hepatocyte-like cells: an experimental research]. ALB, BMSCs, CK18, HGF, HNF4alpha, PAS, YGD
32  2013 Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation. iPSCs, Parp1, PARylation, WT
33  2013 Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia. AAVs
34  2013 Common amino acid sequences deduced from coding exons of the porcine FGF4 gene in two breeds and production of the encoded protein in Escherichia coli. ---
35  2013 Effects of downregulating oct-4 transcript by RNA interference on early development of porcine embryos. ---
36  2013 Expression of FGF4 mRNA is mediated by mating behaviours in mice. ---
37  2013 Fibroblast growth factor-4 enhances proliferation of mouse embryonic stem cells via activation of c-Jun signaling. AP-1, BMMSCs, ERK, ESCs, hPDLSCs, JNK, mESCs
38  2013 Induced maturation of hepatic progenitor cells in vitro. ALB-GLuc, DEX, HGF, HPCs, HS, ICG
39  2013 Noncanonical transforming growth factor beta (TGFbeta) signaling in cranial neural crest cells causes tongue muscle developmental defects. BMP, CNC, FST, TGF-beta
40  2013 Production of bioactive bovine fibroblast growth factor 4 in E. coli based on the common nucleotide sequence of its structural gene in three breeds. ---
41  2012 Common nucleotide sequence of structural gene encoding fibroblast growth factor 4 in eight cattle derived from three breeds. ---
42  2011 A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation. ES, GCTs
43  2011 FGF4-dependent stem cells derived from rat blastocysts differentiate along the trophoblast lineage. REFs, TS
44  2011 Fibroblasts share mesenchymal phenotypes with stem cells, but lack their differentiation and colony-forming potential. FSP, HSP47
45  2011 In vitro trans-differentiation of human umbilical cord derived hematopoietic stem cells into hepatocyte like cells using combination of growth factors for cell based therapy. AFP, CK18, G6P, HGF, HSC, TO
46  2011 Microfluidic perfusion for regulating diffusible signaling in stem cells. ESC, mESC
47  2011 Production of mouse fibroblast growth factor 4 in E. coli and its application for isolation and maintenance of mouse trophoblast stem cells in vitro. RhFGF4, TS
48  2010 Combined vascular endothelial growth factor-A and fibroblast growth factor 4 gene transfer improves wound healing in diabetic mice. MMP-9, VEGF-A
49  2010 Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state. ES, FGFR, HS
50  2009 Aberrant FGF signaling, independent of ectopic hedgehog signaling, initiates preaxial polydactyly in Dorking chickens. Shh
51  2009 An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. ---
52  2009 FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner. AA, GDFs, RA
53  2009 Trophoblast stem cell maintenance by fibroblast growth factor 4 requires MEKK4 activation of Jun N-terminal kinase. EMT, JNK, MMP2, TS
54  2008 Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity. CDK1, TG, TS
55  2008 Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal. FGF4si, HESCs
56  2007 FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. ES
57  2007 Intravenous injection of phagocytes transfected ex vivo with FGF4 DNA/biodegradable gelatin complex promotes angiogenesis in a rat myocardial ischemia/reperfusion injury model. ---
58  2007 Syncytin-A mediates the formation of syncytiotrophoblast involved in mouse placental development. SynT, TS
59  2006 An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival. TS
60  2006 Bi-potential behaviour of cytotrophoblasts in first trimester chorionic villi. EVT, FGFR2, TS
61  2004 Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment. ExE
62  2004 The escape of the mink embryo from obligate diapause. ICM
63  2003 Biodegradable gelatin hydrogel potentiates the angiogenic effect of fibroblast growth factor 4 plasmid in rabbit hindlimb ischemia. DNA, GHG
64  2001 Paracrine and autocrine effects of fibroblast growth factor-4 in endothelial cells. FGFR2, MAE
65  1999 Anabolic effect of aminoterminally truncated fibroblast growth factor 4 (FGF4) on bone. BMD, DEXA, pQCT, rhFGF4s
66  1999 Expression of Fgf4 during early development of the chick embryo. ---
67  1999 Heparin differentially regulates the interaction of fibroblast growth factor-4 with FGF receptors 1 and 2. FGFR, HS
68  1999 Identification of sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch. AP, DV, Shh, Ssq, ZPA
69  1998 FGF4 dissociates anti-tumorigenic from differentiation signals of retinoic acid in human embryonal carcinomas. ECs, RA
70  1998 Promotion of trophoblast stem cell proliferation by FGF4. ---
71  1998 Specific retinoid receptors cooperate to signal growth suppression and maturation of human embryonal carcinoma cells. RA, RARs, RXRs
72  1997 Fibroblast growth factor 4 directs gap junction expression in the mesenchyme of the vertebrate limb Bud. AER, Cx43
73  1996 Ectopic expression of Fgf-4 in chimeric mouse embryos induces the expression of early markers of limb development in the lateral ridge. CNS, SHH
74  1995 An additional limb can be induced from the flank of the chick embryo by FGF4. ---
75  1995 Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. AER, ld, SHH
76  1995 Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. SHH
77  1995 Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity. SHH
78  1993 Assignment of the human RT6 gene to 11q13 by PCR screening of somatic cell hybrids and in situ hybridization. HBB, OMP
79  1993 Quantitative demonstration of spontaneous metastasis by MCF-7 human breast cancer cells cotransfected with fibroblast growth factor 4 and LacZ. ---