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Abbreviation : FLNA
Long Form : filamin A
No. Year Title Co-occurring Abbreviation
2019 Allogeneic mesenchymal stromal cells: Novel therapeutic option for mutated FLNA-associated respiratory failure in the pediatric setting. BM, CT, MSC
2019 Clinical significance of filamin A in patients with acromegaly and its association with somatostatin and dopamine receptor profiles. SRL, sst
2019 Congenital emphysematous lung disease associated with a novel Filamin A mutation. Case report and literature review. PVNH
2019 Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia. MVD
2019 Cytoskeletal Associated Filamin A and RhoA Affect Neural Progenitor Specification During Mitosis. ---
2019 Cytoskeleton actin-binding proteins in clinical behavior of pituitary tumors. ---
2019 Cytoskeleton protein Filamin A is required for efficient Somatostatin receptor type 2 internalization and recycling through Rab5 and Rab4 sorting endosomes in tumor somatotroph cells. GH, SSAs, SST2
2019 Deletion of TMEM268 inhibits growth of gastric cancer cells by downregulating the ITGB4 signaling pathway. ITGB4, TMEM268
2019 Disrupted filamin A/alphaIIbbeta3 interaction induces macrothrombocytopenia by increasing RhoA activity. MKs
10  2019 Filamin A and DRD2 expression in corticotrophinomas. ---
11  2019 Filamin A mediates isotropic distribution of applied force across the actin network. KD, SFs, TS
12  2019 Filamin A regulates EGFR/ERK/Akt signaling andaffects colorectal cancer cell growth and migration. CRC, EGFR
13  2019 Filamin-A as a Balance between Erk/Smad Activities During Cardiac Valve Development. ECM, MVP
14  2019 Formin 2 Regulates Lysosomal Degradation of Wnt-Associated beta-Catenin in Neural Progenitors. Dvl2, Fmn2, Lrp6
15  2019 Fucoidan affects oral squamous cell carcinoma cell functions in vitro by regulating FLNA-derived circular RNA. OSCC
16  2019 Identification of Filamin A Mechanobinding Partner I: Smoothelin Specifically Interacts with the Filamin A Mechanosensitive Domain 21. FLNAvar-1, FRAP, LUZP1, SILAC
17  2019 Identification of Filamin A Mechanobinding Partner II: Fimbacin Is a Novel Actin Cross-Linking and Filamin A Binding Protein. FRAP
18  2019 Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A. FLNA-MVD
19  2019 Overexpression of calpain‑1 predicts poor outcome in patients with colorectal cancer and promotes tumor cell progression associated with downregulation of FLNA. CRC, OS
20  2019 Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis. ---
21  2019 The Host Scaffolding Protein Filamin A and the Exocyst Complex Control Exocytosis during InlB-Mediated Entry of Listeria monocytogenes. PKCalpha, RNAi
22  2019 Upregulation of circFLNA contributes to laryngeal squamous cell carcinoma migration by circFLNA-miR-486-3p-FLNA axis. circRNAs, LSCC
23  2018 A case report on filamin A gene mutation and progressive pulmonary disease in an infant: A lung tissued derived mesenchymal stem cell study. BM-MSC, MSC
24  2018 A novel pathway activated by somatostatin receptor type 2 (SST2): Inhibition of pituitary tumor cell migration and invasion through cytoskeleton protein recruitment. SS, SST2, SST2
25  2018 A novel truncating mutation in FLNA causes periventricular nodular heterotopia, Ehlers-Danlos-like collagenopathy and macrothrombocytopenia. PDA, PVNH
26  2018 Blocking the Cleavage of Filamin A by Calpain Inhibitor Decreases Tumor Cell Growth. ---
27  2018 cAMP/PKA-induced filamin A (FLNA) phosphorylation inhibits SST2 signal transduction in GH-secreting pituitary tumor cells. SSA
28  2018 Filamin A (FLNA) regulates autophagy of bladder carcinoma cell and affects its proliferation, invasion and metastasis. BC, TEM
29  2018 Filamin A expression predicts early recurrence of hepatocellular carcinoma after hepatectomy. ER, HCC
30  2018 Filamin A inhibits tumor progression through regulating BRCA1 expression in human breast cancer. BRCA1
31  2018 Filamin A Is Required for Optimal T Cell Integrin-Mediated Force Transmission, Flow Adhesion, and T Cell Trafficking. ---
32  2018 Filamin A Modulates Store-Operated Ca2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)-Orai1 Association in Human Platelets. SOCE
33  2018 Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells. APCs, TCR
34  2018 FLNA mutations in surviving males presenting with connective tissue findings: two new case reports and review of the literature. ---
35  2018 FLNa negatively regulated proliferation and metastasis in lung adenocarcinoma A549 cells via suppression of EGFR. ABD
36  2018 Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action. IGF-1R
37  2018 Integrity of the corpus callosum in patients with periventricular nodular heterotopia related epilepsy by FLNA mutation. CC, FA, MD, PNH
38  2018 New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study. FLNA-MVD, MVP
39  2018 Proteomics Analysis of Myocardial Tissues in a Mouse Model of Coronary Microembolization. CME, iTRAQ, RhoGDIalpha
40  2018 RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure. A-to-I
41  2018 Single-Molecule Microscopy Reveals Dynamic FLNA Interactions Governing SSTR2 Clustering and Internalization. CCPs, SSTR2
42  2018 Structural basis of the filamin A actin-binding domain interaction with F-actin. ABDs
43  2018 The Inflammatory Transcription Factor C/EBPbeta Plays a Critical Role in Cardiac Fibroblast Differentiation and a Rat Model of Cardiac Fibrosis Induced by Autoimmune Myocarditis. CF, CMF, EAM
44  2018 The LPA-LPA4 axis is required for establishment of bipolar morphology and radial migration of newborn cortical neurons. LPA, LPA4
45  2017 ADP-ribosylation factor-like 4C binding to filamin-A modulates filopodium formation and cell migration. ARL4C, Cdc42
46  2017 Epithelial Sodium Channel-alpha Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction. ASIC1a, CaMKII, ENaC, HLMVEC, PLY
47  2017 Familial Ebstein Anomaly: Whole Exome Sequencing Identifies Novel Phenotype Associated With FLNA. ---
48  2017 Filamin A (FLNA) mutation-A newcomer to the childhood interstitial lung disease (ChILD) classification. chILD, ILD
49  2017 Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors. PAds
50  2017 Filamin A is required for spindle migration and asymmetric division in mouse oocytes. ---
51  2017 Filamin A promotes efficient migration and phagocytosis of neutrophil-like HL-60 cells. FLNs
52  2017 Filamin A Regulates Neutrophil Adhesion, Production of Reactive Oxygen Species, and Neutrophil Extracellular Trap Release. NETs
53  2017 Filamin A upregulation correlates with Snail-induced epithelial to mesenchymal transition (EMT) and cell adhesion but its inhibition increases the migration of colon adenocarcinoma HT29 cells. EMT, FA
54  2017 FilaminA and Formin2 regulate skeletal, muscular, and intestinal formation through mesenchymal progenitor proliferation. Fmn2
55  2017 FLNA is implicated in pulmonary neuroendocrine tumors aggressiveness and progression. PNTs
56  2017 Gain-of-Function Mutation in Filamin A Potentiates Platelet Integrin alphaIIbbeta3 Activation. ---
57  2017 Identification of Filamin-A and -B as potential biomarkers for prostate cancer. FLNB, PrCa
58  2017 Identification of novel autoantigens via mass spectroscopy-based antibody-mediated identification of autoantigens (MS-AMIDA) using immune thrombocytopenic purpura (ITP) as a model disease. aAbs, E1-PDH, HK1, ITP, LFQ, MS-AMIDA
59  2017 Injury induced expression of caveolar proteins in human kidney tubules - role of megakaryoblastic leukemia 1. MKL1, PECs, SCAI, TN-C
60  2017 Left main coronary artery compression by a dilated main pulmonary artery and left coronary sinus of Valsalva aneurysm in a patient with heritable pulmonary arterial hypertension and FLNA mutation. LMCA, MPA, OMI, PAH
61  2017 Liver cyst gene knockout in cholangiocytes inhibits cilium formation and Wnt signaling. ADPLD, ER, GIIA
62  2017 Phosphorylation of filamin A regulates chemokine receptor CCR2 recycling. beta2AR, GPCRs
63  2017 Prion Protein Family Contributes to Tumorigenesis via Multiple Pathways. Dpl, GPI, PDAC, PrP
64  2017 PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis. Abeta42, AD, alpha7nAChR, pM, TLR4
65  2017 Sporadic periventricular nodular heterotopia: Classification, phenotype and correlation with Filamin A mutations. PNH
66  2017 The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling. BioID, E-Syt1, ER, STIM1, UPR
67  2017 Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints. ACPA, GNS, RA, SE
68  2016 A distinct X-linked syndrome involving joint contractures, keloids, large optic cup-to-disc ratio, and renal stones results from a filamin A (FLNA) mutation. ---
69  2016 Actin crosslinking protein filamin A during early pregnancy in the rat uterus. UECs
70  2016 An adventitious interaction of filamin A with RhoGDI2(Tyr153Glu). ---
71  2016 Arterial Myogenic Activation through Smooth Muscle Filamin A. SM
72  2016 Celecoxib exhibits an anti-gastric cancer effect by targeting focal adhesion and leukocyte transendothelial migration-associated genes. ACTN1, CLDN1, CSRP1, DEGs, GC, MYL9, PPIs, THBS1, VCL
73  2016 Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1. PDAC, PrP
74  2016 Comparison of gene expression profiles in aortic dissection and normal human aortic tissues. AD, MYH11, MYLK, RT-qPCR, SOD3, TAGLN
75  2016 Cytoskeletal Filamin A Differentially Modulates RNA Polymerase III Gene Transcription in Transformed Cell Lines. pol
76  2016 Exon skipping causes atypical phenotypes associated with a loss-of-function mutation in FLNA by restoring its protein function. CIPO, PVNH
77  2016 Filamin A (FLNA) modulates chemosensitivity to docetaxel in triple-negative breast cancer through the MAPK/ERK pathway. RNAi, TNBC
78  2016 Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-kappaB Activation in Melanoma Cells by Inhibition of Akt Signaling. IKK, PKCdelta, S1P, TNF
79  2016 Filamin A Is Involved in HIV-1 Vpu-mediated Evasion of Host Restriction by Modulating Tetherin Expression. BST2, HIV-1
80  2016 Filamin A regulates the organization and remodeling of the pericellular collagen matrix. KD, PCM, WT
81  2016 Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Fmn2
82  2016 Filamin A: Insights into its Exact Role in Cancers. ---
83  2016 Filamin-A is required to mediate SST2 effects in pancreatic neuroendocrine tumours. PNETs, SS, SST2
84  2016 Lung disease associated with filamin A gene mutation: a case report. ---
85  2016 Novel X-linked syndrome of cardiac valvulopathy, keloid scarring, and reduced joint mobility due to filamin A substitution G1576R. ---
86  2016 RalA employs GRK2 and beta-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor. ---
87  2016 Smooth muscle filamin A is a major determinant of conduit artery structure and function at the adult stage. SM
88  2016 SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. DDF, HR, NHEJ, RAD51
89  2016 The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A. PHDs, VHL
90  2016 The P2Y2 receptor mediates uptake of matrix-retained and aggregated low density lipoprotein in primary vascular smooth muscle cells. agLDL, HA-tagged, LDLR, P2Y2Rs, VSMCs, WT
91  2016 Tsc1 haploinsufficiency is sufficient to increase dendritic patterning and Filamin A levels. TSC
92  2015 Cross-talk between androgen receptor/filamin A and TrkA regulates neurite outgrowth in PC12 cells. AR
93  2015 Deficiency of filamin A in endothelial cells impairs left ventricular remodelling after myocardial infarction. ECs, LV, MI
94  2015 Deletion of filamin A in monocytes protects cortical and trabecular bone from post-menopausal changes in bone microarchitecture. micro-CT
95  2015 Dopamine and Somatostatin Analogues Resistance of Pituitary Tumors: Focus on Cytoskeleton Involvement. DA, GH, PRL, SS
96  2015 Filamin A interaction with the CXCR4 third intracellular loop regulates endocytosis and signaling of WT and WHIM-like receptors. C-tail, WHIM, WT
97  2015 Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration. F-actin, G-actin, MKL1, SRF
98  2015 Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Collagen Matrix. KD, WT
99  2015 Filamin-a increases the stability and plasma membrane expression of polycystin-2. FLNAC, KD, PC2
100  2015 FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. BAR, DMS, MK