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Abbreviation : FOXO1
Long Form : forkhead box class O1
No. Year Title Co-occurring Abbreviation
2020 Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1. DAC, ENT
2019 FOXO1 Overexpression Attenuates Tubulointerstitial Fibrosis and Apoptosis in Diabetic Kidneys by Ameliorating Oxidative Injury via TXNIP-TRX. DN, KI, KO, ROS
2019 Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment Applications. HIF-1alpha, MnSOD, NCBI GEO, OS, ROS, Sesn3
2019 The Ser/Thr kinase p90RSK promotes kidney fibrosis by modulating fibroblast-epithelial crosstalk. CKD, ROS
2019 The vitamin D receptor (VDR) protects pancreatic beta cells against Forkhead box class O1 (FOXO1)-induced mitochondrial dysfunction and cell apoptosis. DeltaPsim, GDM, PCR, ROS, VDR
2018 FOXO1 Inhibits Tumor Cell Migration via Regulating Cell Surface Morphology in Non-Small Cell Lung Cancer Cells. EMT, NSCLC, SEM
2018 HIF-1-mediated expression of Foxo1 serves an important role in the proliferation and apoptosis of osteoblasts derived from children's iliac cancellous bone. ALP, HIF-1alpha, si
2018 Lentivirus-mediated klotho up-regulation improves aging-related memory deficits and oxidative stress in senescence-accelerated mouse prone-8 mice. CAT, MnSOD, SAMP8
2018 Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells. BL, GC, PI3K
10  2018 Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin (ISO) on human bladder cancer cells. 3'-UTR, BBN, BC, ISO, MIBC
11  2017 FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway. PINK1, STZ, T1D
12  2017 MEK and ERK Kinase Inhibitors Increase Circulating Ceruloplasmin and Cause Green Serum in Rats. MEK
13  2017 Role of STAT3 and FOXO1 in the Divergent Therapeutic Responses of Non-metastatic and Metastatic Bladder Cancer Cells to miR-145. UTR
14  2016 Geniposide Suppresses Hepatic Glucose Production via AMPK in HepG2 Cells. ACC, AMPK, G6Pase, PEPCK, siRNA
15  2016 Isorhapontigenin (ISO) Inhibits Invasive Bladder Cancer Formation In Vivo and Human Bladder Cancer Invasion In Vitro by Targeting STAT1/FOXO1 Axis. BBN, ISO, STAT1
16  2015 Activation of FoxO1/ PGC-1alpha prevents mitochondrial dysfunction and ameliorates mesangial cell injury in diabetic rats. MCs, PGC-1alpha, ROS
17  2015 Forkhead box protein O1 mediates apoptosis in a cancer cervical cell line treated with the antitumor agent tumor necrosis factor-alpha. TNF-alpha
18  2015 Posttranslational modifications of FOXO1 regulate epidermal growth factor receptor tyrosine kinase inhibitor resistance for non-small cell lung cancer cells. NSCLC, TKIs
19  2014 Novel mechanism of blood pressure regulation by forkhead box class O1-mediated transcriptional control of hepatic angiotensinogen. ---
20  2013 Effect of short-term cold exposure on skeletal muscle protein breakdown in rats. EDL, MuRF1, UPS
21  2013 Lithium normalizes amphetamine-induced changes in striatal FoxO1 phosphorylation and behaviors in rats. AMPH, DA, PPI
22  2013 Post-prandial regulation of hepatic glucokinase and lipogenesis requires the activation of TORC1 signalling in rainbow trout (Oncorhynchus mykiss). FAS, GK, SREBP-1c, TORC1
23  2011 Glycine-induced cytoprotection is mediated by ERK1/2 and AKT in renal cells with ATP depletion. Elk1, GlyR, MDCK
24  2011 Tumor necrosis factor-alpha regulates p27 kip expression and apoptosis in smooth muscle cells of human carotid plaques via forkhead transcription factor O1. SMCs, TNF-alpha
25  2010 Ginsenoside Rg1 suppresses hepatic glucose production via AMP-activated protein kinase in HepG2 cells. AMPK, G6Pase, LKB1, PEPCK
26  2010 Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. HFD, PKC
27  2010 Role of the transcriptional factors FOXO1 and PPARG on gene expression of SLC2A4 in endometrial tissue from women with polycystic ovary syndrome. PCOS, PCOSE h-Ins, PPARG
28  2009 Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. HDAC
29  2009 Forkhead transcription factor Foxo1 is essential for adipocyte differentiation. ---
30  2007 Angiopoietin-related growth factor suppresses gluconeogenesis through the Akt/forkhead box class O1-dependent pathway in hepatocytes. AGF, G6Pase, PI3K
31  2005 FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. siRNA, TNF-alpha