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Abbreviation : FTL
Long Form : ferritin light chain
No. Year Title Co-occurring Abbreviation
2019 Adipose Tissue Expansion by Overfeeding Healthy Men Alters Iron Gene Expression. AT, Ft, SAT, Tf
2019 Ferritin: A potential serum marker for lymph node metastasis in head and neck squamous cell carcinoma. FTH, GEO, HNSCC, SF
2019 Screening, identification of prostate cancer urinary biomarkers and verification of important spots. BPH, FTH, MS, PCa, PSA, sh
2019 Sequence analysis of exon 1 of the ferritin light chain (FTL) gene can reveal the rare disorder 'hereditary hyperferritinaemia without cataracts'. ---
2019 The role of transferrin receptor in the Helicobacter pylori pathogenesis; L-ferritin as a novel marker for intestinal metaplasia. CagA, IRP2, TFRC, vacA
2018 Aspirin increases ferroportin 1 expression by inhibiting hepcidin via the JAK/STAT3 pathway in interleukin 6-treated PC-12 cells. AD, FPN1, IL-6, JAK2, PD, STAT3, TfR1
2018 Decreased expression of ferritin light chain in osteosarcoma and its correlation with epithelial-mesenchymal transition. OS, TMAs
2018 Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD. DA, MPTP, PD, SN, SUR1
2018 Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons. ---
10  2018 Different Characteristics of Hepcidin Expression in IL-6+/+ and IL-6-/- Neurons and Astrocytes Treated with Lipopolysaccharides. FPN1, LPS
11  2018 Fasting up-regulates ferroportin 1 expression via a Ghrelin/GHSR/MAPK signaling pathway. FPN1, GHSR1alpha, GOAT, TfR1
12  2018 FTL c.-168G>C Mutation in Hereditary Hyperferritinemia Cataract Syndrome: A New Italian Family. HHCS, IRE
13  2018 Plasma hepcidin is associated with future risk of venous thromboembolism. CIs, ORs, RDW, VTE
14  2017 Association of ferritin with prostate cancer. BPH, FCR, FTH, PCa, PSA
15  2017 Clinical evaluation of a hemochromatosis next-generation sequencing gene panel. ---
16  2017 Effects of alpha-lipoic acid on expression of iron transport and storage proteins in BV-2 microglia cells. ALA, DMT1, FAC, FPN1, Ft-H, TfR1
17  2017 Expression of Iron-Related Proteins Differentiate Non-Cancerous and Cancerous Breast Tumors. BMP6, CD74, ELISA, FPN, FTH, HMGB1, INHA, MyD88, RPPA, STAT3, STAT5, TFRC
18  2017 Ferritin light chain gene mutation in a large Australian family with hereditary hyperferritinemia-cataract syndrome. HHCS, IRE
19  2017 Ferroportin mRNA is down-regulated in granulosa and cervical cells from infertile women. FTH, TFRC
20  2017 Impairment of Hepcidin Upregulation by Lipopolysaccharide in the Interleukin-6 Knockout Mouse Brain. FPN1, IL-6, STAT3
21  2017 Reabsorption of iron into acutely damaged rat liver: A role for ferritins. FTH, TAA
22  2016 Changes in markers associated with dendritic cells drivingthe differentiation of either TH2 cells or regulatoryTcells correlate with clinical benefit during allergen immunotherapy. AIT, C1QA, DC, DC1s, DC2s, RIPK4, SLCO2B1
23  2016 Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy. CNS, DFP, HF, IBs
24  2016 Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway. GBM
25  2016 Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories. C2orf37, COASY, Cp, FA2H, NBIA, PANK2, PLA2G6
26  2015 A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits. ---
27  2015 Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death. FTH, ROS
28  2015 Voxel-based analysis in neuroferritinopathy expands the phenotype and determines radiological correlates of disease severity. UDRS, UHDRS, VBM, VBR
29  2014 A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation. CSF
30  2014 The effect of anti-inflammatory properties of ferritin light chain on lipopolysaccharide-induced inflammatory response in murine macrophages. FTH, IL-1beta, LIP, LPS, NF-kappaB, NO, PGE2, ROS, TNF-alpha
31  2013 Abnormal iron homeostasis and neurodegeneration. HF, IBs
32  2013 Ferritin light chain interacts with PEN-2 and affects gamma-secretase activity. AD, APP, NICD, NTF
33  2013 Iron metabolism disturbances in the MCF-7 human breast cancer cells with acquired resistance to doxorubicin and cisplatin. ---
34  2013 Noncoding variation of the gene for ferritin light chain in hereditary and age-related cataract. IRE, RT-PCR
35  2013 Tumor-associated macrophages as potential diagnostic and prognostic biomarkers in breast cancer. HIFs, PCNA, TAMs, VEGF
36  2012 A mutant light-chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage. HF, IBs, Mt-FTL
37  2012 Ferritin light chain and squamous cell carcinoma antigen 1 are coreceptors for cellular attachment and entry of hepatitis B virus. HBV, HepG2, SCCA1
38  2012 Neuroferritinopathy: update on clinical features and pathogenesis. ---
39  2012 Quantitative proteomics for identifying biomarkers for tuberculous meningitis. Amph, NFASC, PDIA6, SIRPA
40  2012 The effect of pre-existing maternal obesity on the placental proteome: two-dimensional difference gel electrophoresis coupled with mass spectrometry. A1AT, ANXA5, ATPB, BASP1, HNRPC, qRT-PCR, VIME
41  2012 Validation of tumor-associated macrophage ferritin light chain as a prognostic biomarker in node-negative breast cancer tumors: A multicentric 2004 national PHRC study. EMT, IA, IHC, TAM
42  2011 Epidemiology and molecular genetics of congenital cataracts. FGF
43  2011 Hematologic biomarkers in childhood cataracts. ---
44  2011 Hereditary hyperferritinemia-cataract syndrome in two large multigenerational American families. HHCS
45  2010 Accumulation of oxidative DNA damage in brain mitochondria in mouse model of hereditary ferritinopathy. HF, L-PCR, mtDNA
46  2010 High resolution melting for the identification of mutations in the iron responsive element of the ferritin light chain gene. HHCS, HRM, IRE
47  2010 Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. ---
48  2010 Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma. JNK, MAPKs, MDI, OA, PPARgamma, TDI
49  2010 Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration. ---
50  2009 Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene. HF, Tg
51  2009 Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment. ---
52  2008 Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration. ---
53  2007 A novel deletion in the FTL gene causes hereditary hyperferritinemia cataract syndrome (HHCS) by alteration of the transcription start site. HHCS, IRE
54  2006 A new locus for autosomal dominant cataract on chromosome 19: linkage analyses and screening of candidate genes. ADC, LIM2, MIP, SIX5, STS, UTR
55  2006 Sutural cataract associated with a mutation in the ferritin light chain gene (FTL) in a family of Indian origin. 5'-UTR, IRE
56  2006 The candidate gene approach to susceptibility for abdominal aortic aneurysm: TIMP1, HLA-DR-15, ferritin light chain, and collagen XI-Alpha-1. TIMP1
57  2003 A high-throughput screening system for genes extending life-span. ---
58  2002 Neuroferritinopathy: a window on the role of iron in neurodegeneration. ---
59  1997 Identification of a ferritin light chain pseudogene near the glycerol kinase locus in Xp21 by cDNA amplification for identification of genomic expressed sequences. CAIGES