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Abbreviation : FTLD
Long Form : frontotemporal lobar degeneration
No. Year Title Co-occurring Abbreviation
2019 An FTLD-associated SQSTM1 variant impacts Nrf2 and NF-kappaB signalling and is associated with reduced phosphorylation of p62. ALS
2019 Astrocytic ceramide as possible indicator of neuroinflammation. AD, PDD, S1P
2019 Coexisting Lewy body disease and clinical parkinsonism in frontotemporal lobar degeneration. LBD, MSA
2019 Comparison of clinical and neuropathological diagnoses of neurodegenerative diseases in two centres from the Brains for Dementia Research (BDR) cohort. AD, BDR, DLB, FTD
2019 Disease-modifying therapies for tauopathies: agents in the pipeline. FTD
2019 Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia. MFC, OFC, PPA, SE
2019 Elevated YKL-40 and low sAPPbeta:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD. AUC, CSF
2019 FDG-PET underscores the key role of the thalamus in frontotemporal lobar degeneration caused by C9ORF72 mutations. ALS, C9FTLD
2019 Fused in Sarcoma: Properties, Self-Assembly and Correlation with Neurodegenerative Diseases. ALS, FUS, LLPS, PrLDs
10  2019 Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway. AD, ALP
11  2019 Genetics and molecular mechanisms of frontotemporal lobar degeneration: an update and future avenues. ---
12  2019 Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS. FUS, hnRNP
13  2019 HTT gene intermediate alleles in neurodegeneration: evidence for association with Alzheimer's disease. AD, HCs, HD, IAs, IAs, PD
14  2019 Immunological signatures in frontotemporal lobar degeneration. FTD
15  2019 Incidence of frontotemporal lobar degeneration in Italy: The Salento-Brescia Registry study. CI, PY
16  2019 Increased risk of melanoma in C9ORF72 repeat expansion carriers: A case-control study. ALS
17  2019 Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis. ALS, miRNAs, PP1, R-SMAD
18  2019 Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases. AD, NCL, PGRN
19  2019 Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion. ALS, C9orf72, FTD, TDP-43
20  2019 Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis. ALS, LLPS, TDP-43
21  2019 Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains. NFT
22  2019 Prevalence of C9ORF72 Expansion in a Large Series of Patients with Idiopathic Normal-Pressure Hydrocephalus. ALS, iNPH
23  2019 Prominent microglial activation in cortical white matter is selectively associated with cortical atrophy in primary progressive aphasia. AD, PPA
24  2019 Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia. NCL
25  2019 Review: Molecular pathology of frontotemporal lobar degenerations. FUS, TDP-43
26  2019 Review: Neuropathology of non-tau frontotemporal lobar degeneration. FTD
27  2019 RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration. ---
28  2019 Searching for novel cerebrospinal fluid biomarkers of tau pathology in frontotemporal dementia: an elusive quest. AD, CSF, FTD, t-tau
29  2019 SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis. ALS
30  2019 Speech and language intervention for language impairment in patients in the FTD-ALS spectrum. ALS, FTD, PPA, SLT
31  2019 Sustained attention failures on a 3-min reaction time task is a sensitive marker of dementia. AD, PVT, RT
32  2019 TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates. ALS, pTDP-43
33  2019 The association between repeat number in C9orf72 and phenotypic variability in Turkish patients with frontotemporal lobar degeneration. ---
34  2019 The Impact of Cerebral Amyloid Angiopathy in Various Neurodegenerative Dementia Syndromes: A Neuropathological Study. AD, CAA, CBD, LBD, PSP
35  2019 The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD. ALS, CTFs
36  2019 The role of lysosomes and autophagosomes in frontotemporal lobar degeneration. CTSD, DG, LAMP1, LC3A, TCX
37  2019 The Role of the Right Hemisphere in Emotional and Behavioral Disorders of Patients With Frontotemporal Lobar Degeneration: An Updated Review. ---
38  2019 The underacknowledged PPA-ALS: A unique clinicopathologic subtype with strong heritability. ALS, FTD, nfvPPA, PPA, svPPA
39  2019 Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons. ALS
40  2018 A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes. Abeta1-42, AD, AUC, CSF, FTD, p-tau, t-tau
41  2018 A case of semantic variant primary progressive aphasia with Pick's pathology. svPPA, VBM
42  2018 A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies. AD, TAOKs
43  2018 A Review: Mealtime Difficulties following Frontotemporal Lobar Degeneration. ---
44  2018 Aging and cerebrovascular lesions in pure and in mixed neurodegenerative and vascular dementia brains: aneuropathological study. AD, CAA, CoMBs, CoMIs, LBD, WMCs
45  2018 Altered Expression of Circulating Cdc42 in Frontotemporal Lobar Degeneration. AD, Cdc42
46  2018 Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes. AD, ALS, ER, ERAD, UPR
47  2018 Analysis of the substrate recognition state of TDP-43 to single-stranded DNA using fluorescence correlation spectroscopy. ALS, EMSA, FCS, ssDNA, TAR
48  2018 Argyrophilic Grain Pathology in Frontotemporal Lobar Degeneration: Demographic, Clinical, Neuropathological, and Genetic Features. AGD, PSP
49  2018 Atypical parkinsonian syndromes: a general neurologist's perspective. FTD, PPA
50  2018 Biomarkers for diseases with TDP-43 pathology. ALS, TDP-43
51  2018 Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression. AD, ALS, CJD, CON, CSF, DCo, PD
52  2018 Clinical features of the behavioural variant of frontotemporal dementia that are useful for predicting underlying pathological subtypes of frontotemporal lobar degeneration. bvFTD, FUS, MND, TDP
53  2018 Clinical utility of FDG-PET for the clinical diagnosis in MCI. AD, DLB, FDG, MCI, PICO
54  2018 Clinical utility of FDG-PET for the differential diagnosis among the main forms of dementia. AD, DLB, VaD
55  2018 Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum. FTD, FTD-MND, lvPPA, NFL, PPA
56  2018 Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration. AD, CSF, Nf-L, t-tau
57  2018 Different curcumin forms selectively bind fibrillar amyloid beta in post mortem Alzheimer's disease brains: Implications for in-vivo diagnostics. AD, CAA, DLB, PART, PD, TDP-43
58  2018 Differential Neurotoxicity Related to Tetracycline Transactivator and TDP-43 Expression in Conditional TDP-43 Mouse Model of Frontotemporal Lobar Degeneration. hTDP-43, TDP-43, tTA
59  2018 Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients. ALS, DPRs, HSPs
60  2018 Disease-modifying effects of metabolic perturbations in ALS/FTLD. ALS, SOD1, TDP-43
61  2018 Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer's disease. AD, CSF, MDE, miRNAs
62  2018 Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice. Cat, CNS, MEF, NCL, PGRN
63  2018 Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration. AD, bvFTD, CBS, EO, FTD, LO
64  2018 European Association of Nuclear Medicine and European Academy of Neurology recommendations for the use of brain 18 F-fluorodeoxyglucose positron emission tomography in neurodegenerative cognitive impairment and dementia: Delphi consensus. AD, DLB, FDG-PET
65  2018 Exploring the genetics and non-cell autonomous mechanisms underlying ALS/FTLD. ALS, CNS
66  2018 Extended FTLD pedigree segregating a Belgian GRN-null mutation: neuropathological heterogeneity in one family. AD, PART, TDP
67  2018 Flortaucipir tau PET imaging in semantic variant primary progressive aphasia. PET, svPPA, TDP
68  2018 Frequency of frontotemporal dementia gene variants in C9ORF72, MAPT, and GRN in academic versus commercial laboratory cohorts. MAPT
69  2018 Frontotemporal Dementia and Chorea Associated with a Compound Heterozygous TREM2 Mutation. FTD
70  2018 Frontotemporal dementia with trans-activation response DNA-binding protein 43 presenting with catatonic syndrome. FTD, TDP-43
71  2018 Frontotemporal Lobar Degeneration (FTLD): Review and Update for Clinical Neurologists. FTD
72  2018 Frontotemporal Lobe Degeneration as Origin of Scans Without Evidence of Dopaminergic Deficit. DaTSPECT, SWEDD
73  2018 FTLD/ALS-linked TDP-43 mutations do not alter TDP-43's ability to self-regulate its expression in Drosophila. ALS
74  2018 FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-pi Interactions. LC
75  2018 Genetic Modifiers in Neurodegeneration. AD, HD, PD
76  2018 Genotype-phenotype links in frontotemporal lobar degeneration. TDP-43
77  2018 Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila. ALS, TDP-43
78  2018 Importance of Functional Loss of FUS in FTLD/ALS. 3R-Tau, 4R-Tau, ALS, FUS, GluA1, SynGAP1
79  2018 Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center. AD, MCI
80  2018 Low Prevalence of Cancer in Patients withFrontotemporal Lobar Degeneration. AD
81  2018 Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD. ALS, FUS, hnRNP A1
82  2018 Methods to Investigate the Molecular Basis of Progranulin Actions on Brain and Behavior In Vivo Using Knockout Mice. ---
83  2018 Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations. ---
84  2018 Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series. CBD
85  2018 Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity. ALS
86  2018 Monogenic inheritance in early-onset dementia: illustration in Alzheimer's disease and frontotemporal lobar dementia. EOAD, NGS
87  2018 Multiple neuronal pathologies are common in young patients with pathologically proven Frontotemporal lobar degeneration. AD
88  2018 Neurodegeneration of brain networks in the amyotrophic lateral sclerosis-frontotemporal lobar degeneration (ALS-FTLD) continuum: evidence from MRI and MEG studies. ALS, ALS-FTLD, MEG, MRI
89  2018 Novel CSF biomarkers to discriminate FTLD and its pathological subtypes. CSF
90  2018 NPM-hMLF1 fusion protein suppresses defects of a Drosophila FTLD model expressing the human FUS gene. ALS, FUS, hFUS, NPM-hMLF1
91  2018 Olfactory Testing in Frontotemporal Dementia: A Literature Review. FTD
92  2018 Pathogenesis of Frontotemporal Lobar Degeneration: Insights From Loss of Function Theory and Early Involvement of the Caudate Nucleus. ALS, bvFTD, PNFA, SD
93  2018 Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability. RAPP, SRP
94  2018 Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration. ---
95  2018 Pathomechanisms of TDP-43 in neurodegeneration. AD, ALS, HD, PD, TDP-43
96  2018 Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease. ADMA, DPR, MND
97  2018 Possible concurrence of TDP-43, tau and other proteins in amyotrophic lateral sclerosis/frontotemporal lobar degeneration. AD, ALS, NFT, TDP-43
98  2018 Posterior Associative and Cingulate Cortex Involvement of Brain Single-Photon Emission Computed Tomography (SPECT) Imaging in Semantic Dementia with Probable Alzheimer Disease Pathology: A Case Report. AD, SD, SPECT
99  2018 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. OR, TDP-43
100  2018 Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers. AD