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Abbreviation : GC
Long Form : galactocerebroside
No. Year Title Co-occurring Abbreviation
2017 Investigating lipids as a source of chemical exchange-induced MRI frequency shifts. MLVs, WM
2017 MicroRNA-212 inhibits oligodendrocytes during maturation by down-regulation of differentiation-associated gene expression. CNPase, GPCs, MBP, mir-212, OLGs, OPCs, PLP1
2016 The production of human glucocerebrosidase in glyco-engineered Nicotiana benthamiana plants. RNAi
2015 Impaired migration capacity in monocytes derived from patients with Gaucher disease. GD, GlcCerase, PBMCs
2014 Hemorrhagic aspects of Gaucher disease. GCase, GD
2013 Novel mutations in the glucocerebrosidase gene of brazilian patients with Gaucher disease. GD
2013 Remodeling the proteostasis network to rescue glucocerebrosidase variants by inhibiting ER-associated degradation and enhancing ER folding. ERAD, GD
2013 TFEB regulates lysosomal proteostasis. GD, LSDs, TFEB
2012 Human fetal oligodendrocyte progenitor cells from different gestational stages exhibit substantially different potential to myelinate. BDNF, DRGNs, gw, IGF-1, MBP, OPCs, PDGFRalpha
10  2012 Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease. GD, hiPSC
11  2012 Systemic delivery of a glucosylceramide synthase inhibitor reduces CNS substrates and increases lifespan in a mouse model of type 2 Gaucher disease. GluCer, GluSph, nGD
12  2012 VP22 enhances the expression of glucocerebrosidase in human Gaucher II fibroblast cells mediated by lentiviral vectors. GII cells
13  2011 Ca2+ homeostasis modulation enhances the amenability of L444P glucosylcerebrosidase to proteostasis regulation in patient-derived fibroblasts. ER, RyRs
14  2011 Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity. LSD
15  2011 Lacidipine remodels protein folding and Ca 2+ homeostasis in Gaucher's disease fibroblasts: a mechanism to rescue mutant glucocerebrosidase. ---
16  2010 Direct analysis of lipids in mouse brain using electrospray droplet impact/SIMS. EDI, PC, PI, SIMS, ST
17  2010 Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis. ER
18  2009 Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: a biological link between Gaucher disease and parkinsonism. CBE, GCase
19  2009 Glucocerebroside: an evolutionary advantage for patients with Gaucher disease and a new immunomodulatory agent. ERT, GD
20  2008 Detection of mutant protein in complex biological samples: glucocerebrosidase mutations in Gaucher's disease. SELDI-ToF
21  2008 Optimization and validation of two miniaturized glucocerebrosidase enzyme assays for high throughput screening. GBA, HTS
22  2007 Alleviation of acute and chronic graft-versus-host disease in a murine model is associated with glucocerebroside-enhanced natural killer T lymphocyte plasticity. GVHD, NKT
23  2007 Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention. ER
24  2006 AAV8-mediated expression of glucocerebrosidase ameliorates the storage pathology in the visceral organs of a mouse model of Gaucher disease. AAV, BALF, hGC
25  2006 Chemical chaperones and permissive temperatures alter localization of Gaucher disease associated glucocerebrosidase variants. ER, ERAD
26  2006 Glucocerebroside ameliorates the metabolic syndrome in OB/OB mice. NKT
27  2006 Paired helical filaments contain small amounts of cholesterol, phosphatidylcholine and sphingolipids. AD, CH, HPLC, HPTLC, MALDI-TOF MS, PC, PHF, SM
28  2005 Glucocerebroside treatment ameliorates ConA hepatitis by inhibition of NKT lymphocytes. AST, Con A, NKT
29  2005 Improved intracellular delivery of glucocerebrosidase mediated by the HIV-1 TAT protein transduction domain. ERT, TAT
30  2005 Long-term expression of the human glucocerebrosidase gene in vivo after transplantation of bone-marrow-derived cells transformed with a lentivirus vector. HSCs
31  2004 Expression and secretion of human glucocerebrosidase mediated by recombinant lentivirus vectors in vitro and in vivo: implications for gene therapy of Gaucher disease. ---
32  2004 Feasibility of gene therapy in Gaucher disease using an adeno-associated virus vector. rAAV
33  2004 Glucocerebroside inhibits NADPH oxidase activation in cell-free system. ---
34  2003 A2B5 lineages of human astrocytic tumors and their recurrence. AgNORs, GFAP
35  2003 Downregulation of Nogo-A expression of oligodendrocytes in vitro with antisense oligodeoxynucleotides. ODN, RT-PCR
36  2001 Genetically modified bone marrow-derived vehicle cells site specifically deliver an anti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy. IL-1ra, UUO
37  1999 Atypical glial cells in demyelinated and hypomyelinated mouse brains. ---
38  1998 A simple and efficient purification of transduced cells by using green fluorescent protein gene as a selection marker. GFP
39  1998 Inflamed site-specific gene delivery using bone marrow-derived CD11b+CD18+ vehicle cells in mice. gcs, ICAM-1, LPS
40  1998 Long-term expression and secretion of human glucocerebrosidase by primary murine and human myoblasts and differentiated myotubes. GD
41  1998 Methotrexate selectable retroviral vectors for Gaucher disease. hGC, MTX
42  1998 Mice with type 2 and 3 Gaucher disease point mutations generated by a single insertion mutagenesis procedure. SIMP
43  1997 A flow cytometric assay for lysosomal glucocerebrosidase. CBE, FDGlu
44  1997 Detection and isolation of gene-corrected cells in Gaucher disease via a fluorescence-activated cell sorter assay for lysosomal glucocerebrosidase activity. ---
45  1997 Glucocerebrosidase genotype of Gaucher patients in The Netherlands: limitations in prognostic value. ---
46  1997 HIV infection of human fetal neural cells is mediated by gp120 binding to a cell membrane-associated molecule that is not CD4 nor galactocerebroside. CNS, sCD4
47  1997 Toward a transgenic mouse model of remyelination. MBP-lacZ
48  1996 A bicistronic therapeutic retroviral vector enables sorting of transduced CD34+ cells and corrects the enzyme deficiency in cells from Gaucher patients. HSA
49  1996 Complete restoration of glucocerebrosidase deficiency in Gaucher fibroblasts using a bicistronic MDR retrovirus and a new selection strategy. P-gp
50  1996 Increased levels of spliced RNA account for augmented expression from the MFG retroviral vector in hematopoietic cells. ---
51  1996 Studies on the cell tropism of Listeria monocytogenes in ovine fetal brain cell cultures. ---
52  1996 Transplantation and gene transfer of the human glucocerebrosidase gene into immunoselected primate CD34+Thy-1+ cells. BM, PCR, RT
53  1996 [Antibodies to brain galactocerebrosides in the serum and cerebrospinal fluid of patients with disseminated sclerosis]. Ab, MS
54  1995 Cytokine mobilization of peripheral blood stem cells in patients with Gaucher disease with a view to gene therapy. G-CSF, GD, LTC-IC, PBSC
55  1995 Developing oligodendroglia express mRNA for insulin-like growth factor-I, a regulator of oligodendrocyte development. FACS, RT-PCR
56  1995 Efficient retroviral mediated transfer of the glucocerebrosidase gene in CD34+ enriched umbilical cord blood human hematopoietic progenitors. CB, CFU-GM, LTC-IC, PCR
57  1995 Growth factors and stromal support generate very efficient retroviral transduction of peripheral blood CD34+ cells from Gaucher patients. BM, IL-3, PB, SCF
58  1995 Long-term expression of the glucocerebrosidase gene in mouse and human hematopoietic progenitors. CFU-GM, GD, LTC-IC
59  1995 Modulation of Schwann cell Po glycoprotein and galactocerebroside by the surface organization of axolemma. SC
60  1995 Retroviral-mediated gene expression in human myelomonocytic cells: a comparison of hematopoietic cell promoters to viral promoters. CMV, LTR, Mo-MuLV, SV40
61  1995 Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors. CFU
62  1995 The presence of an autologous marrow stromal cell layer increases glucocerebrosidase gene transduction of long-term culture initiating cells (LTCICs) from the bone marrow of a patient with Gaucher disease. CFCs, LTCICs, PCR
63  1994 Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation. BM
64  1994 Cellular expression of an HMGCR promoter-CAT fusion gene in transgenic mouse brain: evidence for a developmental regulation in oligodendrocytes. CAT, CNS, IHC, MBP, OL
65  1994 Correction of the enzyme deficiency in hematopoietic cells of Gaucher patients using a clinically acceptable retroviral supernatant transduction protocol. CFU-GM, IL-3, LTBMC, LTC-IC, LTR, PCR, SCF
66  1994 Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector. ---
67  1994 Expression of human glucocerebrosidase in murine macrophages: identification of efficient retroviral vectors. IL-6, LTR, MoMLV, MPSV, PGK
68  1994 Expression of the human glucocerebrosidase and arylsulfatase A genes in murine and patient primary fibroblasts transduced by an adeno-associated virus vector. AAV, ASA, MLD
69  1994 Infection of murine fetal brain cell cultures with Listeria monocytogenes. ---
70  1994 Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease. GD
71  1994 Murine oligodendroglial cells express nerve growth factor. BDNF, NGF
72  1994 Relaxivity and magnetization transfer of white matter lipids at MR imaging: importance of cerebrosides and pH. Chol, MLV, MT, PC, SPH
73  1994 Retroviral vector design for long-term expression in murine hematopoietic cells in vivo. HSCs
74  1994 Transduction of CD34+ enriched cord blood and Gaucher bone marrow cells by a retroviral vector carrying the glucocerebrosidase gene. ---
75  1994 Transduction of mobilized peripheral blood CD34+ cells with the glucocerebrosidase cDNA. GD, PB
76  1994 Transient expression of 3,5,3'-triiodothyronine nuclear receptors in rat oligodendrocytes: in vivo and in vitro immunocytochemical studies. MBP, OL
77  1994 [Enzyme replacement therapy in type 1 Gaucher's disease]. ---
78  1993 A novel transcript from a pseudogene for human glucocerebrosidase in non-Gaucher disease cells. PCR
79  1993 Evaluation of expression of transferred genes in differentiating myeloid cells: expression of human glucocerebrosidase in murine macrophages. IL-6, LTR, MoMLV
80  1993 Expression of neuromodulin (GAP-43) and its regulation by basic fibroblast growth factor during the differentiation of O-2A progenitor cells. bFGF
81  1993 GFAP expression in the subcutaneous tumors of immature glial cell line (HITS glioma) derived from ENU-induced rat glioma. ENU
82  1993 Purification of olfactory nerve ensheathing cells from the olfactory bulb. O-2A, ONECs
83  1993 Serologic responses to nerve antigens in sooty mangabey monkeys with experimental leprosy. aGM1, ELISA, p.i
84  1992 A distinct type of GD3+, flat astrocyte in rat CNS cultures. ---
85  1992 Differential regulation of cerebroside sulfotransferase and 2',3'-cyclic nucleotide 3'-phosphodiesterase by basic fibroblast growth factor in relation to proliferation in rat oligodendrocyte cultures. bFGF, CNP, CST, OL
86  1992 Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone marrow transduced by a retroviral vector. ---
87  1992 Glycoprotein processing is required for completion but not initiation of oligodendroglial differentiation from its bipotential progenitor cell. CNP, GPDH
88  1992 High levels of human glucocerebrosidase activity in macrophages of long-term reconstituted mice after retroviral infection of hematopoietic stem cells. BM, LTR, MoMLV, mRNA
89  1992 Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow. BMT, LTBMC
90  1991 Effects of gangliosides on the expression of autoimmune demyelination in the peripheral nervous system. EAN, GA
91  1991 Expression of human glucocerebrosidase following retroviral vector-mediated transduction of murine hematopoietic stem cells. BMT
92  1991 Expression of plasmolipin in oligodendrocytes. GFAP
93  1991 Induction of anti-myelin antibodies in EAE and their possible role in demyelination. MBP, PLP
94  1991 Intraorbital transection of the rabbit optic nerve: consequences for ganglion cells and neuroglia in the retina. GFAP
95  1991 Proliferation and differentiation potential of rat forebrain oligodendroglial progenitors both in vitro and in vivo. BrdU
96  1991 Studies of glial lineage and proliferation in vitro using an early marker for committed oligodendrocytes. ASs, GFAP, OLs
97  1991 Toward gene therapy for Gaucher disease. BMT, LTBMC, LTR
98  1990 Expression of human glucocerebrosidase in murine long-term bone marrow cultures after retroviral vector-mediated transfer. HPC, LTBMC
99  1990 Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. GFAP
100  1990 Microtubule associated protein (MAP1B) is present in cultured oligodendrocytes and co-localizes with tubulin. GFAP, MAPs, MBP, MT, PLP