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Abbreviation : GCG
Long Form : glucagon
No. Year Title Co-occurring Abbreviation
2020 A dual GLP-1 and Gcg receptor agonist rescues spatial memory and synaptic plasticity in APP/PS1 transgenic mice. AD, GLP-1, LTP, Oxm, T2DM
2020 A novel long-acting oxyntomodulin analogue eliminates diabetes and obesity in mice. DIO, GLP-1, NASH, OXM, PEG
2020 Comparative analysis of enteroendocrine cells and their hormones between mouse intestinal organoids and native tissues. CCK, EECs, GHRL, Ngn3, Sct
2020 Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide. GLP-1R, TM1
2020 DR10601, a novel recombinant long-acting dual glucagon-like peptide-1 and glucagon receptor agonist for the treatment of obesity and type 2 diabetes mellitus. GLP-1
2020 Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression. DIO, FAox, GCGR, LEPR
2020 Neurotrophic and neuroprotective effects of a monomeric GLP-1/GIP/Gcg receptor triagonist in cellular and rodent models of mild traumatic brain injury. GIP, GLP-1, mTBI
2020 New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice. GLP-1, NASH, OXM
2020 Peptide hormone sensors using human hormone receptor-carrying nanovesicles and graphene FETs. FETs, GCGR, GPCRs, HEK293, PTH, PTHR
10  2019 Aspartame supplementation in starter accelerates small intestinal epithelial cell cycle and stimulates secretion of glucagon-like peptide-2 in pre-weaned lambs. BW, CDK6, GLP-2, GLP-2R, IGF-1, IGF-1R, MTT
11  2019 Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns. FOXO1, INS, SST, T1D, T2D
12  2019 Cracking the combination: Gut hormones for the treatment of obesity and diabetes. GIP, GLP-1, PYY
13  2019 Four targeted genes for predicting the prognosis of colorectal cancer: A bioinformatics analysis case. CLCA1, CRC, DEGs, SLC4A4
14  2019 Glucose-mediated inhibition of calcium-activated potassium channels limits alpha-cell calcium influx and glucagon secretion. AP, IbTX
15  2019 Incretin Mimetics as Rational Candidates for the Treatment of Traumatic Brain Injury. GIP, GLP-1, T2DM, TBI, US
16  2019 Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver. INS, ISS, ORO
17  2019 Pax4 synergistically acts with Pdx1, Ngn3 and MafA to induce HuMSCs to differentiate into functional pancreatic beta-cells. Ad, GCK, HUMSCs, INS, ISL1, MafA, NeuroD1, Ngn3, NKX6.1, PAX4, pbetaCs, pbetaLCs, PCSK1, PCSK2, Pdx1, SLC2A2
18  2019 The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice. BAT, GCGR, HFD, RCD, WT
19  2018 Evolution of the glucagon-like system across fish. GIP, GLP1 and GLP2
20  2018 Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease. AD, GIP, GLP-1, T2DM, TA
21  2018 Polypharmacy through Phage Display: Selection of Glucagon and GLP-1 Receptor Co-agonists from a Phage-Displayed Peptide Library. PDL
22  2018 Smallanthus sonchifolius (Yacon) Flour Improves Visceral Adiposity and Metabolic Parameters in High-Fat-Diet-Fed Rats. HFD, PPAR-gamma2, SD
23  2017 An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation. INS, iPSCs
24  2017 Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas. DEGs, EGFR, FC, FDR, GEO, GnRH, MME, MMP, PPI, SPN, TAGs
25  2017 Central Control of Feeding Behavior by the Secretin, PACAP, and Glucagon Family of Peptides. PACAP, SCT
26  2017 Effect of circulating glucagon and free fatty acids on hepatic FGF21 production in dairy cows. FGF21, NEFA
27  2017 Effects of 13-Hour Hyperglucagonemia on Energy Expenditure and Hepatic Glucose Production in Humans. EE, HGP, INS, OCT, SAL
28  2017 High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting. ESCs
29  2017 Measuring the Pharmacokinetic Properties of Drugs with a Novel Surgical Rat Model. Ex-4, GLP-1, MCR, PK, Vd
30  2017 Single cell transcriptomic profiling of mouse pancreatic progenitors. ---
31  2017 The effect of PPARgamma agonist on SGLT2 and glucagon expressions in alpha cells under hyperglycemia. PPARgamma, SGLT2
32  2017 The species origin of the cellular microenvironment influences markers of beta cell fate and function in EndoC-betaH1 cells. ARX, GSIS
33  2017 [GLP-1/GIP/Gcg receptor Triagonist improves the cognitive behaviors in triple-transgenic mice of Alzheimer's disease]. AD, GIP, GLP-1, T2DM
34  2017 [Role and mechanism of cAMP/Ca 2+ signal pathway in differentiation of bone marrow mesenchymal stem cells into neuronal cells induced by salidroside]. DDIT3, Hspa5, IL-2, Ppp1r15a, PTGS2, SST, TNF
35  2016 Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors. GLP-1
36  2016 Pyridyl-alanine as a Hydrophilic, Aromatic Element in Peptide Structural Optimization. ---
37  2015 Association of LRP5, TCF7L2, and GCG variants and type 2 diabetes mellitus as well as fasting plasma glucose and lipid metabolism indexes. LRP5, SNPs, T2DM, TCF7L2
38  2015 Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs. CHGA, EEC, Gip, HFD, IEC, IESC, IR, LYZ, VC
39  2015 Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. EGP, HNF4A, SGLT2, T2D
40  2014 Evolution of receptors for peptides similar to glucagon. GIP
41  2014 Regeneration of insulin-producing pancreatic cells using a volatile bioactive compound and human teeth. INS, PPY, SST
42  2013 A diet high in resistant starch modulates microbiota composition, SCFA concentrations, and gene expression in pig intestine. DS, RS
43  2013 A novel glucagon-related peptide (GCRP) and its receptor GCRPR account for coevolution of their family members in vertebrates. GCRP, GCRP, GIP, GLP-1, GPCR
44  2013 Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells. DE, INS, iPS, T1D
45  2012 Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling. BAT, GLP-1R, IBAT, OXM, PGDPs, WT
46  2012 Discovery of a novel glucagon-like peptide (GCGL) and its receptor (GCGLR) in chickens: evidence for the existence of GCGL and GCGLR genes in nonmammalian vertebrates. GCGL, GCGR
47  2011 DPP-IV-resistant, long-acting oxyntomodulin derivatives. DPP-IV, GLP-1, OXM
48  2010 Ghrelin affects carbohydrate-glycogen metabolism via insulin inhibition and glucagon stimulation in the zebrafish (Danio rerio) brain. CGM, CNS, gGHRL, GHRL, GHS-R, INS, qPCR, zGHRL
49  2009 Generation of living color transgenic zebrafish to trace somatostatin-expressing cells and endocrine pancreas organization. INS, PP, sst2
50  2009 Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells. ChIP, hIPCs, INS, MafA, NeuroD1, Pdx1
51  2007 WNT signaling pathway and stem cell signaling network. CKI epsilon, FGF, NLK, PPARgamma
52  1997 Genetics of NIDDM in France: studies with 19 candidate genes in affected sib pairs. CCKBR, FABP2, GCKR, HK1, HK2, HRC, ISL1, LDLR
53  1987 Mapping polypeptide hormone genes in the mouse: somatostatin, glucagon, calcitonin, and parathyroid hormone. CALC, PTH, Smst