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Abbreviation : GLUT4
Long Form : glucose transporter 4
No. Year Title Co-occurring Abbreviation
2020 A sea cucumber (Holothuria leucospilota) polysaccharide improves the gut microbiome to alleviate the symptoms of type 2 diabetes mellitus in Goto-Kakizaki rats. CD36, GK, HLP, PI3K, PPAR-alpha, PPARgamma, T2DM
2020 A Systematic Review on Anti-diabetic Properties of Chalcones. ALR, AMP, AMPK, DPP-4, PPARgamma, PTP1B, SGLT2
2020 Age-dependent impairment of adipose-derived stem cells isolated from horses. ASCs, CXCR4, ER, IL-8, INSR, IRE1, Mfn1, TNF-alpha, XBP1
2020 Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes. AA-24-a, AMPK, AS160, CaMKKbeta, IRS-1, MAPK
2020 Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome. BMAL1, IGFBP-4, PCOS, PER, SHBG
2020 Antidiabetic Effect of Casein Glycomacropeptide Hydrolysates on High-Fat Diet and STZ-Induced Diabetic Mice via Regulating Insulin Signaling in Skeletal Muscle and Modulating Gut Microbiota. GHP, LPSs, T2D
2020 Assessment of the Phenolic Profiles, Hypoglycemic Activity, and Molecular Mechanism of Different Highland Barley (Hordeum vulgare L.) Varieties. G6Pase, GSK3beta, GYS2, IRS-1, PEPCK, PI3K, T2DM
2020 BAG6 contributes to glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4. ---
2020 Berberine decreases insulin resistance in a PCOS rats by improving GLUT4: Dual regulation of the PI3K/AKT and MAPK pathways. HOMA-IR, ISI, PCOS, SD
10  2020 Beta-sitosterol attenuates insulin resistance in adipose tissue via IRS-1/Akt mediated insulin signaling in high fat diet and sucrose induced type-2 diabetic rats. IR, SIT
11  2020 Cancer‑related fatigue during combined treatment of androgen deprivation therapy and radiotherapy is associated with mitochondrial dysfunction. ADT, CNS, NMPC, PBMCs, RT, TFAM, VWRA
12  2020 Caulerpa okamurae extract attenuates inflammatory interaction, regulates glucose metabolism and increases insulin sensitivity in 3T3-L1 adipocytes and RAW 264.7 macrophages. COE, IRS-1, NO, TNF-alpha
13  2020 CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis. ERGIC
14  2020 Cooperative effects of galanin and leptin on alleviation of insulin resistance in adipose tissue of diabetic rats. ---
15  2020 Differential Diabetogenic Effect of Pitavastatin and Rosuvastatin, in vitro and in vivo. ---
16  2020 Distinct cardiac energy metabolism and oxidative stress adaptations between obese and non-obese type 2 diabetes mellitus. ATGL, FFAs, Nrf2, p-GSK-3beta, PPARalpha, ROS, T2DM
17  2020 Downregulated ABHD5 Aggravates Insulin Resistance of Trophoblast Cells During Gestational Diabetes Mellitus. ABHD5, AMPK, GDM, HG, INSR, PI3K, qRT-PCR
18  2020 Effect of beta-sitosterol on glucose homeostasis by sensitization of insulin resistance via enhanced protein expression of PPRgamma and glucose transporter 4 in high fat diet and streptozotocin-induced diabetic rats. PPARgamma
19  2020 Effect of chromium citrate on the mechanism of glucose transport and insulin resistance in Buffalo rat liver cells. AMPKalpha2, BRL, IR, IRS-1, PI3K, PPARgamma
20  2020 Effect of Dietary Silk Peptide on Obesity, Hyperglycemia, and Skeletal Muscle Regeneration in High-Fat Diet-Fed Mice. HFD, SP, UCP3, VAT
21  2020 Effects of a fermented buckwheat flower and leaf extract on the blood glucose and lipid profile of type 2 diabetic db/db mice. EFBFL, FFA, FINS, FPG, HOMA-IR, LDL-C, MEG, NCG, OGTT, PPARgamma, RBG, TC, TG
22  2020 Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms. DCI, GSK3beta, IRS2, PI3K
23  2020 Ellagic Acid and Urolithins A and B Differentially Regulate Fat Accumulation and Inflammation in 3T3-L1 Adipocytes While Not Affecting Adipogenesis and Insulin Sensitivity. EA, FA, IL-6, iNOS, LPS, MCP-1, p-Akt, p-NF-kappaB, PPARgamma, TNF-alpha
24  2020 Exercise Training-Induced PPARbeta Increases PGC-1alpha Protein Stability and Improves Insulin-Induced Glucose Uptake in Rodent Muscles. CS, Cyto C, Ext, NUO, PGC1alpha, PPARbeta
25  2020 Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes. AMPK, mTOR, NNMT
26  2020 Hyperbaric Oxygen Ameliorates Insulin Sensitivity by Increasing GLUT4 Expression in Skeletal Muscle and Stimulating UCP1 in Brown Adipose Tissue in T2DM Mice. ARC, ATA, BAT, HBO, HFD, NPY, p-Akt, STZ, T2DM, UCP1
27  2020 IL-29 promoted obesity-induced inflammation and insulin resistance. HFD, IL-29, MCP-1, SGBS
28  2020 Impact of curcumin treatment on diabetic albino rats. GLUT1, HF, STZ
29  2020 Improving effect of vitamin D supplementation on obesity-related diabetes in rats. IRS-1, p-IRS-1, VDR
30  2020 Low-concentration exposure to organochlorine pesticides (OCPs) in L6 myotubes and RIN-m5F pancreatic beta cells induces disorders of glucose metabolism. OCPs, ROS
31  2020 LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells. aggLDL, CE, CVD, IR, LRP1
32  2020 MicroRNA-15a Inhibits Glucose Transporter 4 Translocation and Impairs Glucose Metabolism in L6 Skeletal Muscle Via Targeting of Vesicle-Associated Membrane Protein-Associated Protein A. miR-15a, VAP-A
33  2020 Network pharmacology and metabolomics study on the intervention of traditional Chinese medicine Huanglian Decoction in rats with type 2 diabetes mellitus. FBG, FINS, HLD, HOMA-IR, HPLC-MS, INSR, ISI, MAPK1, STZ, T2DM, TCA, TCM
34  2020 Overfeeding During Lactation in Rats is Associated with Cardiovascular Insulin Resistance in the Short-Term. eNOS, IR, MAPK, PI3K
35  2020 Pectin lyase-modified red ginseng extract improves glucose homeostasis in high fat diet-fed mice. HFD, OGTT
36  2020 Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice. ALT, AST, G6PD, GLU, PerO, PI3K, STZ, T2DM, TC, TGs
37  2020 Peroxiredoxin 2 deficiency does not affect insulin resistance and oxidative stress in high-fat diet-fed obese mice. KO, Prx2, WT
38  2020 Reduced Glucose Tolerance and Skeletal Muscle GLUT4 and IRS1 Content in Cyclists Habituated to a Long-Term Low-Carbohydrate, High-Fat Diet. IRS-1, LCHF
39  2020 Role of LXR alpha in regulating expression of glucose transporter 4 in adipocytes - Investigation on improvement of health of diabetic patients. FLL, LXRalpha
40  2020 Stress adaptation disorders play a role in rat gestational diabetes with oxidative stress and glucose transporter-4 expression. GDM, IL-6, MDA, NC, NE, SOD
41  2020 The regulatory protein 14-3-3beta binds to the IQ motifs of myosin-IC independent of phosphorylation. CaM, CaMKII
42  2020 Thyroid Deficiency Before Birth Alters the Adipose Transcriptome to Promote Overgrowth of White Adipose Tissue and Impair Thermogenic Capacity. GO, KEGG, ML, PAT, PPARgamma, pS6K, UCP1, UL
43  2020 [Effect of Fei-Liu-Ping ointment combined with cyclophosphamide on lung cancer cell proliferation and acidic microenvironment]. CAIX, GRP78, HIF-1alpha, HK1, IL-2, Treg
44  2019 1-Deoxynojirimycin modulates glucose homeostasis by regulating the combination of IR-GlUT4 and ADIPO-GLUT4 pathways in 3T3-L1 adipocytes. ADIPO, AMP, DNJ, IR, PI3K, T2DM
45  2019 A Detection Method for GLUT4 Exocytosis Based on Spontaneous Split Luciferase Complementation. ---
46  2019 A high-throughput chemical-genetics screen in murine adipocytes identifies insulin-regulatory pathways. ---
47  2019 Adipocytes initiate an adipose-cerebral-peripheral sympathetic reflex to induce insulin resistance during high-fat feeding. HF, IR, RAS, ROS, SM, SNS
48  2019 Akt is a critical node of acute myocardial insulin resistance and cardiac dysfunction after cardiopulmonary bypass. CPB
49  2019 alpha, beta-Amyrin, a pentacyclic triterpenoid from Protium heptaphyllum suppresses adipocyte differentiation accompanied by down regulation of PPARgamma and C/EBPalpha in 3T3-L1 cells. PPARgamma
50  2019 Ameliorating effect of sesamin on insulin resistance of hepatic L02 cells induced by high glucose/high insulin. INSR, IRS-1, IRS2, SES
51  2019 Amelioration by quercetin of insulin resistance and uterine GLUT4 and ERalpha gene expression in rats with polycystic ovary syndrome (PCOS). DHEA, ERalpha, GK, HK, HOMA-IR, IR, PCOS
52  2019 AMPK and PPARbeta positive feedback loop regulates endurance exercise training-mediated GLUT4 expression in skeletal muscle. AMPK, MEF2A, PGC-1alpha, PPARbeta
53  2019 Annexins in Adipose Tissue: Novel Players in Obesity. ANXA1
54  2019 Anthraquinone-type inhibitor of alpha-glucosidase enhances glucose uptake by activating an insulin-like signaling pathway in C2C12 myotubes. MTAQ
55  2019 Anti-Diabetic Effect of a Shihunine-Rich Extract of Dendrobium loddigesii on 3T3-L1 Cells and db/db Mice by Up-Regulating AMPK-GLUT4-PPARalpha. AMP, DLS, PPARalpha
56  2019 Antidiabetic Activity and Potential Mechanism of Amentoflavone in Diabetic Mice. AME, G6Pase, GCK, GSK-3, HDL-C, LDL-C, MDA, PEPCK, PFK-1, PK, SOD, TC, TG
57  2019 Antidiabetic and Antihyperlipidemic Effects of Sulphurenic Acid, a Triterpenoid Compound from Antrodia camphorata, in Streptozotocin-Induced Diabetic Mice. FAS, Feno, Glib, PPARalpha, SA, SREBP, STZ, TC, TG
58  2019 Antidiabetic role of a novel protein from garlic via NO in expression of Glut-4/insulin in liver of alloxan induced diabetic mice. AEG, NGPG, NO
59  2019 Antioxidant Effects of Oral Ang-(1-7) Restore Insulin Pathway and RAS Components Ameliorating Cardiometabolic Disturbances in Rats. CAT, CT, FAT, MetS, RAS, SOD, TBARS
60  2019 Apigenin-induced HIF-1alpha inhibitory effect improves abnormal glucolipid metabolism in AngⅡ/hypoxia-stimulated or HIF-1alpha-overexpressed H9c2 cells. ANP, CPT-1, FFA, GPAT, HIF-1alpha, PDK-4
61  2019 Butyrate Improves the Metabolic Disorder and Gut Microbiome Dysbiosis in Mice Induced by a High-Fat Diet. CAD, CVD, HFD, MS, pAMPK
62  2019 Carbenoxolone enhances peripheral insulin sensitivity and GLUT4 expression in skeletal muscle of obese rats: Potential participation of UBC9 protein. CBX, MSG, SAT, Slc2a4, UBC9
63  2019 Celastrol Reverses Palmitic Acid-Induced Insulin Resistance in HepG2 Cells via Restoring the miR-223 and GLUT4 Pathway. IR, IRS-1, miRNAs, PA
64  2019 Centella asiatica (L.) extract attenuates inflammation and improve insulin sensitivity in a coculture of lipopolysaccharide (LPS)-induced 3T3-L1 adipocytes and RAW 264.7 macrophages. IL-6, IRS-1, LPS
65  2019 Chenodeoxycholic Acid Ameliorates AlCl3-Induced Alzheimer's Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats. Abeta42, AD, BACE1, BDNF, CDCA, CREB, FXR, GLP-1, PPARgamma, pSer307-IRS1
66  2019 Cooperation between galanin and insulin in facilitating glucose transporter 4 translocation in adipose cells of diabetic rats. VAMP2
67  2019 Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise. NOX2, ROS
68  2019 Decreased adipocyte glucose transporter 4 (GLUT4) and aquaglyceroporin-7 (AQP7) in adults with morbid obesity: possible early markers of metabolic dysfunction. AQP7, DM2, Glut, IR, OB, pAktII, PE, Visc, WI
69  2019 Deoxyelephantopin suppresses hepatic stellate cells activation associated with inhibition of aerobic glycolysis via hedgehog pathway. ASMA, DET, Hh, HK, HSCs, PFK-2
70  2019 Diabetic Hemodialysis: Vitamin D Supplementation and its Related Signaling Pathways Involved in Insulin and Lipid Metabolism. HD, IRS-1, LDLR, PBMCs, PDK1, PKC, PPARgamma
71  2019 Discovery of novel pyridazine derivatives as glucose transporter type 4 (GLUT4) translocation activators. SAR
72  2019 Effect of berberine on the HPA-axis pathway and skeletal muscle GLUT4 in type 2 diabetes mellitus rats. BBR, HPA, IR, T2DM
73  2019 Effect of combination of chlorella intake and aerobic exercise training on glycemic control in type 2 diabetic rats. Akt, OLETF, PI3K
74  2019 Effect of Ishophloroglucin A, A Component of Ishige okamurae, on Glucose Homeostasis in the Pancreas and Muscle of High Fat Diet-Fed Mice. HFD, IO, IPA
75  2019 Effect of Litsea lancifolia Leaf Extract on Glucose Transporter 4 Translocation and Glucose Uptake in 3T3L1 Cell Line. ---
76  2019 Effect of phytase on intestinal phytate breakdown, plasma inositol concentrations, and glucose transporter type 4 abundance in muscle membranes of weanling pigs1. Ca, NC, PC
77  2019 Effect of pomegranate seed oil supplementation on the GLUT-4 gene expression and glycemic control in obese people with type 2 diabetes: A randomized controlled clinical trial. FBS, PSO, T2DM
78  2019 Effects of Agriophyllum squarrosum extracts on glucose metabolism in KKAy mice and the associated underlying mechanisms. AGEs, ASE, GSK3beta, GSP, HASEG, IRS2, LASEG, MASEG, MCG, MEG, NCG, P-IRS2, PAS, PI3K
79  2019 Effects of histone deacetylase inhibitor Scriptaid and parathyroid hormone on osteocyte functions and metabolism. HDAC, MEF2, PTH
80  2019 Effects of Microbial Metabolites of (-)-Epigallocatechin Gallate on Glucose Uptake in L6 Skeletal Muscle Cell and Glucose Tolerance in ICR Mice. AMPK, EGCG
81  2019 Effects of sodium salicylate on glucose kinetics and insulin signaling in postpartum dairy cows. G6PC, PC, SS
82  2019 Egg white hydrolysate and peptide reverse insulin resistance associated with tumor necrosis factor-alpha (TNF-alpha) stimulated mitogen-activated protein kinase (MAPK) pathway in skeletal muscle cells. EWH, JNK, MAPK, TNF-alpha
83  2019 Eicosapentaenoic Acid (EPA) Modulates Glucose Metabolism by Targeting AMP-Activated Protein Kinase (AMPK) Pathway. AMPK, BCAAs, CaMKK, EPA, p38 MAPK
84  2019 Electrochemiluminescence Investigation of Glucose Transporter 4 Expression at Skeletal Muscle Cells Surface Based on a Graphene Hydrogel Electrode. CDs, ECL, GH, HSMCs
85  2019 Electroporated GLUT4-7myc-GFP detects in vivo glucose transporter 4 translocation in skeletal muscle without discernible changes in GFP patterns. AMPK
86  2019 Eugenol ameliorates insulin resistance, oxidative stress and inflammation in high fat-diet/streptozotocin-induced diabetic rat. AMPK, HFD, HOMA-IR, STZ
87  2019 Evaluation of the effects of bredemolic acid on selected markers of glucose homeostasis in diet-induced prediabetic rats. BA, HFHC, ND, PD
88  2019 Expression, purification and biological activity of monomeric insulin precursors from methylotrophic yeasts. MIP
89  2019 Gastric Sleeve Surgery Alleviates Obesity-Associated Insulin Resistance and Suppresses Endoplasmic Reticulum Stress in Adipose Tissue of db/db Mice. ER
90  2019 GLP‑1 improves palmitate‑induced insulin resistance in human skeletal muscle via SIRT1 activity. cAMP, HSMMs, PGC1alpha, PKA, siRNA, SIRT1
91  2019 Glycyrrhetinic Acid Improves Insulin-Response Pathway by Regulating the Balance between the Ras/MAPK and PI3K/Akt Pathways. FFA, GA, JNK, MAPK, PKC, PMA
92  2019 Golden sea cucumber extract revives glucose transporter-4 and interleukin-6 protein level in diabetic mouse muscle. IL-6, PC, STZ
93  2019 Green Tea Ameliorates Hyperglycemia by Promoting the Translocation of Glucose Transporter 4 in the Skeletal Muscle of Diabetic Rodents. EGCG
94  2019 Heparin affects cytosolic glucose responses of hyperglycemic dividing mesangial cells. RMCs
95  2019 High Dose of Dietary Nicotinamide Riboside Induces Glucose Intolerance and White Adipose Tissue Dysfunction in Mice Fed a Mildly Obesogenic Diet. eWAT, NR, SIRT1
96  2019 Hydrogen sulfide potentiates the favorable metabolic effects of inorganic nitrite in type 2 diabetic rats. GTT, HFD, NaSH, NO, PTT, STZ, T2D
97  2019 Hydroxyoleoside-type seco-iridoids from Symplocos cochinchinensis and their insulin mimetic activity. 2-NBDG, ECD, PTP1B
98  2019 Hypoglycaemic effects of glimepiride in sulfonylurea receptor 1 deficient rat. SUs, TALEN
99  2019 Hypoglycemic effects of wheat bran alkyresorcinols in high-fat/high-sucrose diet and low-dose streptozotocin-induced type 2 diabetic male mice and protection of pancreatic beta cells. ARs, FBG, FINS, GLUT2, HDL-C, HFSD, LDL-C, OGTT, STZ, T2DM, TC, TG
100  2019 Impaired Myocardial MIF/AMPK Activation Aggravates Myocardial Ischemia Reperfusion Injury in High-Fat Diet-Induced Obesity. AMPK, I/R, MIF