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Abbreviation : GPC1
Long Form : glypican-1
No. Year Title Co-occurring Abbreviation
2020 Anti-glypican-1 antibody-drug conjugate is a potential therapy against pancreatic cancer. ADC, MMAF
2020 Combined Exosomal GPC1, CD82, and Serum CA19-9 as Multiplex Targets: A Specific, Sensitive, and Reproducible Detection Panel for the Diagnosis of Pancreatic Cancer. CA19-9, CD82
2020 Exosomal glypican-1 for risk stratification of pancreatic cystic lesions: A case of pathological progression in the absence of any suspicious imaging finding. ---
2020 Glypican-1 Level Is Elevated in Extracellular Vesicles Released from MC38 Colon Adenocarcinoma Cells Overexpressing Snail. EMT, EVs
2020 GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab. CAR
2020 HSPGs glypican-1 and glypican-4 are human neuronal proteins characteristic of different neural phenotypes. BDNF, hNSCs, HSPGs, PDGF-B
2020 Human Milk Oligosaccharides Mediate the Crosstalk Between Intestinal Epithelial Caco-2 Cells and Lactobacillus PlantarumWCFS1in an In Vitro Model with Intestinal Peristaltic Shear Force. 2'-FL, CLDN3, DEFB1, EXT1, HAS1, hMOs, TJP1
2020 Molecular analysis of lymphoid tissue from rhesus macaque rhadinovirus-infected monkeys identifies alterations in host genes associated with oncogenesis. AICDA, BAC, CX3CR1, KSHV, LN, LPD, RasD1, RM, RRV, SIV, TXNIP, vCD200
2020 Near-Infrared Molecular Imaging of Glioblastoma by Miltuximab-IRDye800CW as a Potential Tool for Fluorescence-Guided Surgery. FGS, GBM, IR800, NIR, TBR
10  2020 Proinflammatory cytokines induce accumulation of glypican-1-derived heparan sulfate and the C-terminal fragment of beta-cleaved APP in autophagosomes of dividing neuronal cells. APP, HS, LTR, SDS-PAGE
11  2020 Sensitive Signal Amplifying a Diagnostic Biochip Based on a Biomimetic Periodic Nanostructure for Detecting Cancer Exosomes. ---
12  2020 Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab antibody against glypican-1 (GPC-1). PCa
13  2020 The proteomic analysis of breast cell line exosomes reveals disease patterns and potential biomarkers. GLUT1, UC
14  2020 The Role of Glypican-1 in the Tumour Microenvironment. EMT, Hh, TME
15  2019 CD63-GPC1-Positive Exosomes Coupled with CA19-9 Offer Good Diagnostic Potential for Resectable Pancreatic Ductal Adenocarcinoma. EUS-FNA, EVs, PDAC
16  2019 Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. FGF-2, GPCs, GPI
17  2019 Glypican-1 and glycoprotein 2 bearing extracellular vesicles do not discern pancreatic cancer from benign pancreatic diseases. BPD, EVs, GP2, PDAC
18  2019 Glypican-1 Promotes Tumorigenesis by Regulating the PTEN/Akt/beta-Catenin Signaling Pathway in Esophageal Squamous Cell Carcinoma. EMT, ESCC, IHC
19  2019 High Clinical Value of Liquid Biopsy to Detect Circulating Tumor Cells and Tumor Exosomes in Pancreatic Ductal Adenocarcinoma Patients Eligible for Up-Front Surgery. CTCs, PDAC
20  2019 Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth. TCM
21  2019 The Expression, Regulation, and Biomarker Potential of Glypican-1 in Cancer. ---
22  2018 Advanced fabrication of biosensor on detection of Glypican-1 using S-Acetylmercaptosuccinic anhydride (SAMSA) modification of antibody. DPV, SAMSA, ToF-SIMS
23  2018 Anti-glypican-1 antibody-drug conjugate exhibits potent preclinical antitumor activity against glypican-1 positive uterine cervical cancer. ADC, MMAF, SCCs
24  2018 Detection of glypican-1 (GPC-1) expression in urine cell sediments in prostate cancer. BPH, CIs, IFA, OR, PSA
25  2018 Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden. crExos, ELISA, PDAC
26  2018 Glypican-1-antibody-conjugated Gd-Au nanoclusters for FI/MRI dual-modal targeted detection of pancreatic cancer. DTPA, FI/MRI, MR, PC
27  2018 Prognostic value of glypican-1 for patients with advanced pancreatic cancer following regional intra-arterial chemotherapy. APC, EVs, OS, RIAC
28  2017 A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. CP, miR-10b, PDAC
29  2017 Alterations in mandibular morphology associated with glypican 1 and glypican 3 gene mutations. GPC3
30  2017 Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma. PDAC
31  2017 EVI1 modulates oncogenic role of GPC1 in pancreatic carcinogenesis. EVI1, IPMNs, PDAC
32  2017 Glypican-1 targeted antibody-based therapy induces preclinical antitumor activity against esophageal squamous cell carcinoma. ESCC, mAb
33  2017 High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas. GBM, MGMT, OS
34  2017 Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate. HNSCC
35  2016 Glypican-1 in exosomes as biomarker for early detection of pancreatic cancer. ---
36  2016 Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish. ADD3, BA, Hh, MO, XPNPEP1
37  2016 Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma. ESCC, iTRAQ
38  2015 Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. crExos
39  2015 Suppression of glypican-1 autodegradation by NO-deprivation correlates with nuclear accumulation of amyloid beta in normal fibroblasts. anMan-HS, APP, HS, SNO, WT MEF
40  2014 Autoregulation of glypican-1 by intronic microRNA-149 fine tunes the angiogenic response to FGF2 in human endothelial cells. ECs, miR-149
41  2014 Shear-induced endothelial NOS activation and remodeling via heparan sulfate, glypican-1, and syndecan-1. EC, eNOS, GCX, Hep III, HS, NO, SDC1
42  2013 Glypican 1 stimulates S phase entry and DNA replication in human glioma cells and normal astrocytes. CDK2, CKIs, ERK, MAPK, PI3K
43  2013 GPC-1 may serve as a predictor of perineural invasion and a prognosticator of survival in pancreatic cancer. GDNF, MMP-9
44  2013 Non-toxic amyloid beta formed in the presence of glypican-1 or its deaminatively generated heparan sulfate degradation products. anMan, APP, HS, PG, SNO
45  2013 Regulation of bone morphogenetic protein signalling and cranial osteogenesis by Gpc1 and Gpc3. BMPs, GPC3
46  2013 Sonic hedgehog regulates its own receptor on postcrossing commissural axons in a glypican1-dependent manner. Hhip
47  2013 Thyroid hormone treated astrocytes induce maturation of cerebral cortical neurons through modulation of proteoglycan levels. T3-treated
48  2012 A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis. CX3CL1, FGF-2, HBGFs, ITGB3, PDACs, VEGF-A
49  2012 Glypican-1 stimulates Skp2 autoinduction loop and G1/S transition in endothelial cells. CKIs, ECs
50  2011 Suppression of amyloid beta A11 antibody immunoreactivity by vitamin C: possible role of heparan sulfate oligosaccharides derived from glypican-1 by ascorbate-induced, nitric oxide (NO)-catalyzed degradation. AD, anMan, APP, HS, NO
51  2010 Altering Glypican-1 levels modulates canonical Wnt signaling during trigeminal placode development. ---
52  2010 Effect of glypican-1 gene on the pulp cells during the reparative dentine process. ---
53  2009 FARP2, HDLBP and PASK are downregulated in a patient with autism and 2q37.3 deletion syndrome. aCGH, FARP2, FISH, KIF1A, PASK
54  2008 Discovery of a novel molecule that regulates tumor growth and metastasis. ---
55  2008 Expression profile analysis of aorta-gonad-mesonephros region-derived stromal cells reveals genes that regulate hematopoiesis. AGM, HSCs, S3-A9
56  2008 Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells. HBGFs
57  2008 Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells. APC/C, ECs
58  2008 Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells. AD, HS, HSPGs, SDC3
59  2008 Involvement of glypican-1 autoprocessing in scrapie infection. HS
60  2006 Constitutive and vitamin C-induced, NO-catalyzed release of heparan sulfate from recycling glypican-1 in late endosomes. anMan, HS, NO, NPC-1
61  2006 Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma. NPT, PDAC
62  2006 Defective nitric oxide-dependent, deaminative cleavage of glypican-1 heparan sulfate in Niemann-Pick C1 fibroblasts. HS, NO, NPC1, NPC2
63  2004 Molecular delineation of deletions on 2q37.3 in three cases with an Albright hereditary osteodystrophy-like phenotype. AHO, FISH, GPR35, STK25
64  2004 Two further AHO-like syndrome patients with deletion of glypican 1 gene region in 2q37.2-q37.3. AHO-like, FISH
65  2003 Glypican-1 is a vehicle for polyamine uptake in mammalian cells: a pivital role for nitrosothiol-derived nitric oxide. HS