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Abbreviation : GSTpi
Long Form : glutathione S-transferase pi
No. Year Title Co-occurring Abbreviation
2021 GSTpi reduces DNA damage and cell death by regulating the ubiquitination and nuclear translocation of NBS1. ADR, MMS, NBS1
2021 Lycium Barbarum Polysaccharides and Wolfberry Juice Prevent DEHP-Induced Hepatotoxicity via PXR-Regulated Detoxification Pathway. CYP2E1, CYP3A1, DEHP, ELISA, GST, LBP, PXR, RXRalpha, UGT1, WJ
2021 Renal impairment assessment on adults living nearby a landfill: Early kidney dysfunction biomarkers linked to the environmental exposure to heavy metals. Cyst C, GST-alpha, KIM-1, NGAL, OPN, RBP, TFF3, TIMP1
2020 Development of pH/Glutathione-Responsive Theranostic Agents Activated by Glutathione S-Transferase pi for Human Colon Cancer. ---
2020 Effects of EHP-101 on inflammation and remyelination in murine models of Multiple sclerosis. CBD, Gjc3, HIF, MBP, MS, Olig2
2020 Study on the pharmacological character of an insulin-mimetic small molecular compound of vanadyl trehalose. GCLC, GSH-Px, GSR, GSS, VC, VT
2019 Human glutathione-S-transferase pi potentiates the cysteine-protease activity of the Der p 1 allergen from house dust mite through a cysteine redox mechanism. HDM
2019 Knockdown of long non-coding RNA LINC00152 increases cisplatin sensitivity in ovarian cancer cells. MDR1, MRP1, siRNAs
2019 S-Glutathionylation of mouse selenoprotein W prevents oxidative stress-induced cell death by blocking the formation of an intramolecular disulfide bond. Grx1, SELENOW, Trx
10  2018 Design and synthesis of new hybrids from 2-cyano-3,12-dioxooleana- 9-dien-28-oic acid and O2-(2,4-dinitrophenyl) diazeniumdiolate for intervention of drug-resistant lung cancer. CDDO, NO, ROS
11  2018 Dual Intratumoral Redox/Enzyme-Responsive NO-Releasing Nanomedicine for the Specific, High-Efficacy, and Low-Toxic Cancer Therapy. AIE, NO, PDHNs
12  2018 Expression of multidrug-resistance associated proteins in human retinoblastoma treated by primary enucleation. LRP, ON, P-gp, Rb
13  2018 Glutathione S-Transferase Pi is Involved in the Growth of Mice. ELISA, GH, NBDHEX
14  2018 Glutathione S-Transferase pi-Activatable O2-(Sulfonylethyl Derived) Diazeniumdiolates Potently Suppress Melanoma in Vitro and in Vivo. ---
15  2018 Glutathione S-transferase pi: a potential role in antitumor therapy. ---
16  2018 Regulation of Endothelial Permeability by Glutathione S-Transferase Pi Against Actin Polymerization. HSP27, MAPK, TNF-alpha
17  2017 O2-(2,4-dinitrophenyl)diazeniumdiolates derivatives: Design, synthesis, cytotoxic evaluation and reversing MDR in MCF-7/ADR cells. ADR, NO
18  2016 Expression of Autophagy and Reactive Oxygen Species-Related Proteins in Lacrimal Gland Adenoid Cystic Carcinoma. ACC, BNIP3, LC, MnSOD, OS, ROS
19  2016 PEP-1-GSTpi protein enhanced hippocampal neuronal cell survival after oxidative damage. ---
20  2016 The Aqueous Fraction of Areca catechu Nut Ameliorates Demyelination in Prefrontal Cortex-Induced Depressive Symptoms and Cognitive Decline through Brain-Derived Neurotrophic Factor-Cyclic Adenosine Monophosphate Response Element-Binding Activation. ANE, BDNF, cAMP, CNPase, MBP
21  2016 [Reversal Effect of Dihydromyricetin on Drug Resistance of K562/A02 Cell Line to Adriamycin]. DMY, MRP1, P-gp
22  2015 Comparison of PBDE congeners as inducers of oxidative stress in zebrafish. COX6a, GST, NAC, PBDEs, TRAP1
23  2015 Effects of a nutrient mixture on immunohistochemical localization of cancer markers in human cervical cancer HeLa cell tumor xenografts in female nude mice. Bcl-2, COX-2, iNOS, MMP, NM, TUNEL, VEGF
24  2015 Lower antioxidative capacity of multidrug-resistant cancer cells confers collateral sensitivity to protoflavone derivatives. HIF-1alpha, MDR, MnSOD, ROS/RNS
25  2015 Quantification of bindings of organometallic ruthenium complexes to GSTpi by mass spectrometry. ESI-MS
26  2015 The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination. CC, EAE, KL, PDGFRalpha, WT
27  2015 The shifting perception on antioxidants: the case of vitamin E and beta-carotene. ---
28  2014 Discovery of tumor markers for gastric cancer by proteomics. A1AT, apoAI, GC, GKN-1, GRP78, IHC, WB
29  2014 Expression of glutathione, glutathione peroxidase and glutathione S-transferase pi in canine mammary tumors. GSH-Px, GSS
30  2014 Expression of reactive oxygen species-related proteins according to androgen and HER-2 status in estrogen receptor-negative breast cancer. AR, ER, MnSOD, TXNIP, TxNR
31  2014 Sensitization of mesothelioma cells to platinum-based chemotherapy by GSTpi knockdown. ---
32  2013 GSTpi protects against angiotensin II-induced proliferation and migration of vascular smooth muscle cells by preventing signal transducer and activator of transcription 3 activation. Ang II, STAT3, VSMCs
33  2013 Hybrid molecule from O2-(2,4-dinitrophenyl)diazeniumdiolate and oleanolic acid: a glutathione S-transferase pi-activated nitric oxide prodrug with selective anti-human hepatocellular carcinoma activity and improved stability. NO, OA
34  2013 Organometallic ruthenium anticancer complexes inhibit human glutathione-S-transferase pi. ---
35  2013 Sildenafil (Viagra) protective effects on neuroinflammation: the role of iNOS/NO system in an inflammatory demyelination model. WT
36  2013 The expression of redox proteins in phyllodes tumor. MnSOD, PT, ROS, TXNIP, TxNR
37  2012 Effects of geranyl-phloroacetophenone on the induction of apoptosis and chemosensitization of adriamycin-resistant MCF-7 human breast cancer cells. 3-GAP
38  2012 Nrf2-dependent and Nrf2-independent induction of phase 2 detoxifying and antioxidant enzymes during keratinocyte differentiation. HO-1, KC, NQO-1, Nrf2
39  2012 Role of Nrf2 antioxidant defense in mitigating cadmium-induced oxidative stress in the olfactory system of zebrafish. Cd, gclc, HMOX1, OSNs, PRDX1, SFN
40  2012 Targeting to overexpressed glucose-regulated protein 78 in gastric cancer discovered by 2D DIGE improves the diagnostic and therapeutic efficacy of micelles-mediated system. A1AT, GC, GRP78
41  2012 The synthesis of ethacrynic acid thiazole derivatives as glutathione S-transferase pi inhibitors. EA
42  2011 Alterations in glutathione S-transferase pi expression following exposure to MPP+ -induced oxidative stress in the blood of Parkinson's disease patients. ---
43  2011 Differences in glutathione S-transferase pi expression in transgenic mice with symptoms of neurodegeneration. ---
44  2011 Glutathione transferase pi (GSTpi) expression in breast cancer: an immunohistochemical and molecular study. ---
45  2011 Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin. FAD, FADS, FMN, GR, RF, RFK
46  2011 Ligustrazine derivate DLJ14 reduces multidrug resistance of K562/A02 cells by modulating GSTpi activity. ADR, MDR
47  2011 Nuclear translocation of glutathione S-transferase pi is mediated by a non-classical localization signal. ---
48  2011 Organ specific Gst-pi expression of the metastatic androgen independent prostate cancer cells in nude mice. ROS
49  2010 Decreased expression of GST pi is correlated with a poor prognosis in human esophageal squamous carcinoma. ---
50  2010 Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase pi. MAPK, MMP, ROS
51  2009 Clinical relevance of human cancer xenografts as a tool for preclinical assessment: example of in-vivo evaluation of topotecan-based chemotherapy in a panel of human small-cell lung cancer xenografts. IFO, LRP, MDR1, MRP, SCLC, TPT
52  2009 Glutathione S-transferase pi regulates UV-induced JNK signaling in SH-SY5Y neuroblastoma cells. JNK
53  2009 Prognostic value of ERCC1, thymidylate synthase, and glutathione S-transferase pi for 5-FU/oxaliplatin chemotherapy in advanced colorectal cancer. ERCC1, LV, OS, TS
54  2009 Rapid induction of P-glycoprotein mRNA and protein expression by cytarabine in HL-60 cells. AML, BCRP, DNR, P-gp
55  2008 Catalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits. ---
56  2008 Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier. MRP2, PCN, PXR
57  2008 GSTpi expression in MPTP-induced dopaminergic neurodegeneration of C57BL/6 mouse midbrain and striatum. ---
58  2008 Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress. JNK
59  2008 Technetium-99m-hexakis-2-methoxyisobutylisonitrile scintigraphy and multidrug resistance-related protein expression in human primary lung cancer. CT, MDR, MRP, P-gp, SPECT, T/B
60  2007 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. CDNB, JNK1, OZO
61  2007 Evaluation of the MDR1, ABCG2, Topoisomerases IIalpha and GSTpi gene expression in patients affected by aggressive mantle cell lymphoma treated by the R-Hyper-CVAD regimen. MCL
62  2007 The effects of cyclooxygenase-2 expression in prostate cancer cells: modulation of response to cytotoxic agents. COX, LNCaPCOX-2
63  2006 Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes. ---
64  2006 Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. TIA
65  2006 Prx1 suppresses radiation-induced c-Jun NH2-terminal kinase signaling in lung cancer cells through interaction with the glutathione S-transferase Pi/c-Jun NH2-terminal kinase complex. JNK, ROS
66  2006 [Reversal of multidrug resistance of human hepatocellular carcinoma cells by wild-type p53 gene and related mechanisms]. HCC, MDR, MDR1, MRP, P-gp, RT-PCR, topo II alpha, VCR, wtp53
67  2005 A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins. NO, PTP1B
68  2005 A study of glutathione S-transferase pi expression in central nervous system of subjects with amyotrophic lateral sclerosis using RNA extraction from formalin-fixed, paraffin-embedded material. ALS, FFPE
69  2005 Synthesis and anticancer activity of 2-alkylaminomethyl-5-diaryl-methylenecyclopentanone hydrochlorides and related compounds. ---
70  2005 Value of glutathion-S transferase pi as a prognostic factor in epithelial ovarian carcinoma. pCR, PFS
71  2005 [Reversal effect of haloperidol on doxorubicin resistance and chloride channel inhibition in erythroleukemic cell K562/Dox]. DOX, HAL, MRP, RVD
72  2004 Dual effects of glutathione-S-transferase pi on As2O3 action in prostate cancer cells: enhancement of growth inhibition and inhibition of apoptosis. ---
73  2004 Influence of glutathione S-transferase pi and p53 expression on tumor frequency and spectrum in mice. JNK
74  2004 Methylation profile of the promoter CpG islands of 14 "drug-resistance" genes in hepatocellular carcinoma. ABCG2, B2M, CAT, dCK, HCC, OCLN, RAF1, RalBP1
75  2004 Nuclear glutathione S-transferase pi prevents apoptosis by reducing the oxidative stress-induced formation of exocyclic DNA products. 13-HPODE
76  2003 Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways. ---
77  2003 Monobromobimane occupies a distinct xenobiotic substrate site in glutathione S-transferase pi. CDNB, mBBr
78  2003 [Identification of the ligand binding sites and novel drug target molecules by photoaffinity labeling]. GB
79  2002 Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage. MLH1
80  2002 Cell differentiation lineage in the prostate. CK19
81  2002 Cellular sensitivity determinants to docetaxel in human gastrointestinal cancers. beta-TUB
82  2002 Expression of glutathione s-transferase pi in benign mucosa, Barrett's metaplasia, and adenocarcinoma of the esophagus. ---
83  2002 Fractionated irradiation of H69 small-cell lung cancer cells causes stable radiation and drug resistance with increased MRP1, MRP2, and topoisomerase IIalpha expression. SCLC
84  2002 Glutathione S-transferase pi Protects Serum Depletion-induced Cell Death by Inhibiting ASK1-MKK7-JNK Pathway in the 293 Cells. ASK1
85  2002 I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma. BPH
86  2002 Prognostic value of multidrug resistance 1, glutathione-S-transferase-pi and p53 in advanced nasopharyngeal carcinoma treated with systemic chemotherapy. NPC
87  2002 [Reversal of nomegestrol acetate on multidrug resistance in drug-resistant human breast cancer cell line MCF7/ADR]. FCM, MDR, MRP, NOM, RT-PCR, topo II alpha
88  2001 Pathological excretion patterns of urinary proteins in miners highly exposed to dinitrotoluene. DNT, GST-alpha, SDS-PAGE
89  2001 Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. MEFs
90  2001 Reversal effects of nomegestrol acetate on multidrug resistance in adriamycin-resistant MCF7 breast cancer cell line. ADR, DRO, FCM, MDR, MG, MRP, NOM, P-gp, RT-PCR, TAM, topo IIalpha, VRP
91  2001 [Modulation of multiple drug resistance by nomegestrol acetate and droloxifene in K562/A02]. ADM, DRO, FCM, MRP, NOM, topo II alpha
92  2000 Overexpression of glutathione S-transferase pi enhances the adduct formation of cisplatin with glutathione in human cancer cells. ---
93  2000 Overexpression of the 27 KDa heat shock protein is associated with thermoresistance and chemoresistance but not with radioresistance. ---
94  2000 Prognostic value of immunoexpression of the chemoresistance-related proteins in ependymomas: an analysis of 76 cases. ChRPs, MT, P-gp
95  2000 Prognostic value of p53, glutathione S-transferase pi, and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in head and neck cancer. OS, TS
96  1999 Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. APL, GPx
97  1999 Low-dose cisplatin and 5-fluorouracil in combination can repress increased gene expression of cellular resistance determinants to themselves. 5-FU, DPD, MRP, TS
98  1999 Suppression of N-methyl-N'-nitro-N-nitrosoguanidine- and S-nitrosoglutathione-induced apoptosis by Bcl-2 through inhibiting glutathione-S-transferase pi in NIH3T3 cells. ARE, MNNG
99  1998 Biological indicators of survival in patients treated by surgery for squamous cell carcinoma of the oral cavity and oropharynx. TLI
100  1998 Glutathione S-transferase pi immunostaining of cisplatin-resistant ovarian cancer cells in ascites. ---