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Abbreviation : HAT
Long Form : human African trypanosomiasis
No. Year Title Co-occurring Abbreviation
2020 Assessing the impact of aggregating disease stage data in model predictions of human African trypanosomiasis transmission and control activities in Bandundu province (DRC). ---
2020 Centering Patient Expectations of a Novel Home-Based Oral Drug Treatment among T. b. rhodesiense Human African Trypanosomiasis Patients in Uganda. ---
2020 Clinical Study on the Melarsoprol-Related Encephalopathic Syndrome: Risk Factors and HLA Association. ES, HLA
2020 Design and synthesis of alpha-phenoxy-N-sulfonylphenyl acetamides as Trypanosoma brucei Leucyl-tRNA synthetase inhibitors. LeuRS
2020 Gambiense Human African Trypanosomiasis Sequelae after Treatment: A Follow-Up Study 12 Years after Treatment. DRC
2020 Monitoring the presence of trypanosomes' DNA - Including Trypanosoma brucei gambiense DNA - From the midguts of riverine Glossina trapped in the south east outskirts of Kinshasa City (Democratic Republic of Congo). ---
2020 New Drugs for Human African Trypanosomiasis: A Twenty First Century Success Story. DNDi
2020 Prescription of concomitant medications in patients treated with Nifurtimox Eflornithine Combination Therapy (NECT) for T.b. gambiense second stage sleeping sickness in the Democratic Republic of the Congo. DRC, NECT, WHO
2020 Whose Elimination? Frontline Workers' Perspectives on the Elimination of the Human African Trypanosomiasis and Its Anticipated Consequences. ---
10  2019 A mathematical model for evaluating the role of trypanocide treatment of cattle in the epidemiology and control of Trypanosoma brucei rhodesiense and T. b. gambiense sleeping sickness in Uganda. ---
11  2019 A Microfluidic-Based Microscopy Platform for Continuous Interrogation of Trypanosoma brucei during Environmental Perturbation. ---
12  2019 Antileishmanial and antitrypanosomal activity of symmetrical dibenzyl-substituted alpha,beta-unsaturated carbonyl-based compounds. ---
13  2019 Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon. VNTR
14  2019 Association of APOL1 renal disease risk alleles with Trypanosoma brucei rhodesiense infection outcomes in the northern part of Malawi. T.b
15  2019 Case Report: Trypanosoma brucei Gambiense Human African Trypanosomiasis as the Cause of Fever in an Inpatient with Multiple Myeloma and HIV-1 Coinfection. T.b
16  2019 Cerebrospinal Fluid-Derived Microvesicles From Sleeping Sickness Patients Alter Protein Expression in Human Astrocytes. CNS, CSF, Int, MVs, TEM
17  2019 Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis. SRA, TgsGP, VSG
18  2019 Comparative in vitro transportation of pentamidine across the blood-brain barrier using polycaprolactone nanoparticles and phosphatidylcholine liposomes. BBB, NPs, PCL
19  2019 Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)-Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei. CNSL
20  2019 Drug Discovery for Kinetoplastid Diseases: Future Directions. ---
21  2019 Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents. ADME, NTDs
22  2019 Evaluation of the Anti-Trypanosomal Activity of Vietnamese Essential Oils, with Emphasis on Curcuma longa L. and Its Components. EOs, SIs, Tbb
23  2019 Fexinidazole: First Global Approval. DNDi
24  2019 Flavonoid-derived Privileged Scaffolds in anti-Trypanosoma brucei Drug Discovery. ---
25  2019 Generation of neuroinflammation in human African trypanosomiasis. IFN, IL, TNF
26  2019 Geoclimatology and sleep in Africa: A mini-review. ---
27  2019 Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics. ---
28  2019 Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China. ---
29  2019 Human African Trypanosomiasis: Progress and Stagnation. ---
30  2019 Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays. DHFR, PTR1, TbDHFR, TbPTR1
31  2019 Improvement of Aqueous Solubility of Lapatinib-Derived Analogues: Identification of a Quinolinimine Lead for Human African Trypanosomiasis Drug Development. ---
32  2019 Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth. TbGSK3s
33  2019 Integration of Human African Trypanosomiasis Control Activities into Primary Healthcare Services: A Scoping Review. ---
34  2019 Is the elimination of 'sleeping sickness' affordable? Who will pay the price? Assessing the financial burden for the elimination of human African trypanosomiasis Trypanosoma brucei gambiense in sub-Saharan Africa. NTDs, OOPs, Tbg
35  2019 Passive Screening and Diagnosis of Sleeping Sickness with New Tools in Primary Health Services: An Operational Research. ---
36  2019 Plasma cytokine profiles associated with rhodesiense sleeping sickness and falciparum malaria co-infection in North Eastern Uganda. IFN-gamma, IL, TGF-beta, TNF-alpha
37  2019 Preparation of Sesquiterpene Lactone-Loaded PLA Nanoparticles and Evaluation of Their Antitrypanosomal Activity. NPs, PLA, STLs, T. b. r
38  2019 Proteome characterization in various biological fluids of Trypanosoma brucei gambiense-infected subjects. CSF
39  2019 Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns). CATT
40  2019 Resolving the apparent transmission paradox of African sleeping sickness. ---
41  2019 Short- and long-term effects of orally administered azithromycin on Trypanosoma brucei brucei-infected mice. AAT, AZM, DA
42  2019 Sleep and brain infections. ---
43  2019 Sleeping sickness in the historical focus of forested Guinea: update using a geographically based method. GIS, IVR
44  2019 Sustainable Elimination (Zero Cases) of Sleeping Sickness: How Far Are We from Achieving This Goal? ---
45  2019 Targeting a Large Active Site: Structure-Based Design of Nanomolar Inhibitors of Trypanosoma brucei Trypanothione Reductase. hGR, TR
46  2019 The elimination of Trypanosoma brucei gambiense? Challenges of reservoir hosts and transmission cycles: Expect the unexpected. ---
47  2019 The Flipside of Eradicating a Disease; Human African Trypanosomiasis in a Woman in Rural Democratic Republic of Congo: A Case Report. ---
48  2019 The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham's discovery 50 years ago to a gold standard for sleeping sickness diagnosis. CATT, DEAE, mAECT
49  2019 The Trypanosomal Transferrin Receptor of Trypanosoma Brucei-A Review. AT, Tf, TfR
50  2019 Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria. ---
51  2019 Trypanosoma brucei gambiense excreted/secreted factors impair lipopolysaccharide-induced maturation and activation of human monocyte-derived dendritic cells. DCs, ESF, LPS, moDCs
52  2019 Trypanosoma brucei gambiense Group 2: The Unusual Suspect. Tbb, Tbg, Tbr
53  2019 Understanding Structure-Activity Relationships for Trypanosomal Cysteine Protease Inhibitors by Simulations and Free Energy Calculations. SAR, TI
54  2019 Update on human African trypanosomiasis (sleeping sickness). ---
55  2019 Using detergent-enhanced LAMP for African trypanosome detection in human cerebrospinal fluid and implications for disease staging. CSF, LAMP, POC
56  2019 Variations of Glossina sp. and trypanosome species frequency within different habitats in a sleeping sickness focus, Gabon. ---
57  2018 A 3D-QSAR Study on the Antitrypanosomal and Cytotoxic Activities of Steroid Alkaloids by Comparative Molecular Field Analysis. CoMFA, PLS, SAR, SDEP, T. b. r
58  2018 A dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei. dcAdoMet
59  2018 A multicentre, randomised, non-inferiority clinical trial comparing a nifurtimox-eflornithine combination to standard eflornithine monotherapy for late stage Trypanosoma brucei gambiense human African trypanosomiasis in Uganda. CSF, ITT, mITT, PP
60  2018 A Phase III Diagnostic Accuracy Study of a Rapid Diagnostic Test for Diagnosis of Second-Stage Human African Trypanosomiasis in the Democratic Republic of the Congo. CSF
61  2018 Accuracy, Ease of Use, Safety, and Acceptability of a 23-muL Conical Cup Blood Transfer Device for Use with Rapid Diagnostic Tests. BTD, HWs, RDTs
62  2018 Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides. ---
63  2018 Combining paratransgenesis with SIT: impact of ionizing radiation on the DNA copy number of Sodalis glossinidius in tsetse flies. AAT, AW-IPM, SIT
64  2018 Cost-effectiveness of using a rapid diagnostic test to screen for human African trypanosomiasis in the Democratic Republic of the Congo. CATT, DRC, RDTs
65  2018 Description of the first sleeping sickness case diagnosed in Burkina Faso since two decades. ---
66  2018 Detection of Wolbachia and different trypanosome species in Glossina palpalis palpalis populations from three sleeping sickness foci of southern Cameroon. ---
67  2018 Differences in pathogenicity and virulence of Trypanosoma brucei gambiense field isolates in experimentally infected Balb/C mice. PCV, T. b. gambiense
68  2018 Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro. ---
69  2018 Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? WHO
70  2018 Folates in Trypanosoma brucei: Achievements and Opportunities. DNDi, WHO
71  2018 FRET Flow Cytometry-Based High Throughput Screening Assay To Identify Disrupters of Glucose Levels in Trypanosoma brucei. ---
72  2018 Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles. MOA
73  2018 Identification of highly effective antitrypanosomal compounds in essential oils from the Apiaceae family. SI
74  2018 Insights into antitrypanosomal drug mode-of-action from cytology-based profiling. MOA
75  2018 Integrating innovations: a qualitative analysis of referral non-completion among rapid diagnostic test-positive patients in Uganda's human African trypanosomiasis elimination programme. RDTs
76  2018 Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan. KAP
77  2018 Mathematical Modelling of Human African Trypanosomiasis Using Control Measures. ---
78  2018 Mini-review on CRISPR-Cas9 and its potential applications to help controlling neglected tropical diseases caused by Trypanosomatidae. AAT, NTDs
79  2018 Monitoring the elimination of human African trypanosomiasis: Update to 2016. NGOs, NSSCP, WHO
80  2018 Morphological changes, nitric oxide production, and phagocytosis are triggered in vitro in microglia by bloodstream forms of Trypanosoma brucei. CNS
81  2018 Mortality trends and risk factors in advanced stage-2 Human African Trypanosomiasis: A critical appraisal of 23 years of experience in the Democratic Republic of Congo. DRC
82  2018 MRI findings of the brain in human African trypanosomiasis: a case series and review of the literature. PCR, T2WFLAIR
83  2018 Neural Damage in Experimental Trypanosoma brucei gambiense Infection: Hypothalamic Peptidergic Sleep and Wake-Regulatory Neurons. MCH, OX, PVT, SCN, T.b
84  2018 Neural Damage in Experimental Trypanosoma brucei gambiense Infection: The Suprachiasmatic Nucleus. SCN, T.b
85  2018 No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations. CGAS, SNP, T. b. r, Tbg
86  2018 Novel triazine dimers with potent antitrypanosomal activity. ---
87  2018 Polyamines in protozoan pathogens. ---
88  2018 Prevalence of Sodalis glossinidius and different trypanosome species in Glossina palpalis palpalis caught in the Fontem sleeping sickness focus of the southern Cameroon. PCR
89  2018 Prospective evaluation of a rapid diagnostic test for Trypanosoma brucei gambiense infection developed using recombinant antigens. CATT, RDTs
90  2018 Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. hCatL, RD, T.b
91  2018 Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation. ---
92  2018 Sleeping Sickness in the 'Omics Era. NGOs
93  2018 Species-Selective Pyrimidineamine Inhibitors of Trypanosoma brucei S-Adenosylmethionine Decarboxylase. AdoMetDC
94  2018 Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. TDH
95  2018 Structure-Based Virtual Screening and Biochemical Evaluation for the Identification of Novel Trypanosoma brucei Aldolase Inhibitors. NTD, SBVS
96  2018 Synthesis and Biological Activity of Sterol 14alpha-Demethylase and Sterol C24-Methyltransferase Inhibitors. 24-SMT
97  2018 Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors. ---
98  2018 The conserved hypothetical protein Tb427.10.13790 is required for cytokinesis in Trypanosoma brucei. ---
99  2018 The impact of passive case detection on the transmission dynamics of gambiense Human African Trypanosomiasis. ---
100  2018 The Long Wait for a New Drug for Human African Trypanosomiasis. ---