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Abbreviation : HCTZ
Long Form : hydrochlorothiazide
No. Year Title Co-occurring Abbreviation
2022 Antihypertensive effect of Equisetum arvense L.: a double-blind, randomized efficacy and safety clinical trial. CBP, DBP, EMA, SAH, SBP
2022 Design of a pragmatic clinical trial embedded in the Electronic Health Record: The VA's Diuretic Comparison Project. CTD, DCP, PROBE
2022 Does hydrochlorothiazide increase the incidence of skin, lip and oral cancer in a UK population? BCC, HIV, IRRs, NMSC, SCC
2022 Hydrochlorothiazide use is associated with the risk of cutaneous and lip squamous cell carcinoma: A systematic review and meta-analysis. ---
2022 Low Salt Delivery Triggers Autocrine Release of Prostaglandin E2 From the Aldosterone-Sensitive Distal Nephron in Familial Hyperkalemic Hypertension Mice. ASDN, CNT, DCT, ENaC, FHHt, PGE2, SPAK
2022 Pathophysiologic Approach to Understanding and Successfully Treating Idiopathic Edema: Unappreciated Importance of Nocturia. IE, VMP
2021 Advanced eco-friendly UV spectrophotometric approach for resolving overlapped spectral signals of antihypertensive agents in their binary and tertiary pharmaceutical dosage form. AML, CLO, TEL
2021 Chlorthalidone versus hydrochlorothiazide: major cardiovascular events, blood pressure, left ventricular mass, and adverse effects. CTD, MACE
2021 Congenital nephrogenic diabetes insipidus accompanied with central nephrogenic diabetes secondary to pituitary surgery -a case report. AVPR2, CDI, CNDI, DI
10  2021 Effect of adding hydrochlorothiazide to usual treatment of patients with acute decompensated heart failure: a randomized clinical trial. ADHF
11  2021 Effects of firibastat in combination with enalapril and hydrochlorothiazide on blood pressure and vasopressin release in hypertensive DOCA-salt rats. APA, BP, DOCA, RAS
12  2021 Efficacy of ARB/HCTZ Combination Therapy in Uncontrolled Hypertensive Patients Compared with ARB Monotherapy: A Meta-Analysis. AEs, ARB, CI, RCTs
13  2021 High-intensity interval training vs. hydrochlorothiazide on blood pressure, cardiovascular health and cognition: Protocol of a non-inferiority trial. BP, HIIT
14  2021 Hydrochlorothiazide and risk of melanoma subtypes. CIs, ORs
15  2021 Hydrochlorothiazide Use and Risk of Nonmelanoma Skin Cancers: A Biological Plausibility Study. NMSCs
16  2021 Is there a link between Non melanoma skin cancer and hydrochlorothiazide? BCC, NMSC, ORs, SCC
17  2021 Pathophysiologically based antihypertensive pharmacotherapeutics rationality, efficacy and safety in Sub Saharan African Nations - A review. AHD, CAD, CCB, CKD, DM, HT, MTD, SSA, TD, TLD, UBP
18  2021 Plasma metabolomic profiles associated with hypertension and blood pressure in response to thiazide diuretics. BP, HTN
19  2021 Race-Specific Comparisons of Antihypertensive and Metabolic Effects of Hydrochlorothiazide and Chlorthalidone. ---
20  2021 Risk of Nonmelanoma Skin Cancer in Association With Use of Hydrochlorothiazide-Containing Products in the United States. ACEIs, BCC, CI, HRs, IRRs, SCC
21  2021 Risk of skin cancer in new users of thiazides and thiazide-like diuretics: a cohort study using an active comparator group. BCC, BFT, CCBs, CI, CMM, IRRs, IRs, PS, RDs, SCC, TZs
22  2021 Sex difference in kidney electrolyte transport III: Impact of low K intake on thiazide-sensitive cation excretion in male and female mice. GFR, LK, NCC, pNCC, UV
23  2021 Superior antihypertensive and cardioprotective effects of chlorthalidone compared with hydrochlorothiazide. CTD
24  2021 Supersaturating drug delivery systems containing fixed-dose combination of two antihypertensive drugs: Formulation, in vitro evaluation and molecular metadynamics simulations. ASD, CC, DSC, FTIR, HPMCAS, XRPD
25  2021 Tagetes erecta L. flowers, a medicinal plant traditionally used to promote diuresis, induced diuretic and natriuretic effects in normotensive and hypertensive rats. HETE, LC-DAD-MS, NTR
26  2021 The effect of amiloride in decreasing albuminuria in patients with diabetic kidney diseases: a prospective, crossover, open-label study. DKD, suPAR, UACR, UPCR
27  2021 The Risk of Cutaneous Squamous Cell Carcinoma Among Patients with Type 2 Diabetes Receiving Hydrochlorothiazide: A Cohort Study. cSCC
28  2021 Thiazide-Sensitive NCC (Sodium-Chloride Cotransporter) in Human Metabolic Syndrome: Sodium Sensitivity and Potassium-Induced Natriuresis. NCC
29  2021 Use of hydrochlorothiazide and risk of skin cancer in a large nested case-control study in Spain. BCC, KC, MM, SCC
30  2021 UV-Vis LED-assisted photo-Fenton process for mineralization of losartan and hydrochlorothiazide: optimization using desirability function. DOC, LOS
31  2021 Validation of population pharmacokinetic models: a comparison of internal and external validation approaches for hydrochlorothiazide. ---
32  2020 Angiotensin Converting Enzyme Inhibitors Combined with Exercise for Hypertensive Seniors (The ACES Trial): Study Protocol of a Randomized Controlled Trial. ACE
33  2020 Association between Use of Hydrochlorothiazide and Nonmelanoma Skin Cancer: Common Data Model Cohort Study in Asian Population. NMSC, PSM
34  2020 Cardiovascular Benefits of Angiotensin-Converting Enzyme Inhibition Plus Calcium Channel Blockade in Patients Achieving Tight Blood Pressure Control and With Resistant Hypertension. ACEI, BP, CCB, CI, HR
35  2020 Combining angiotensin receptor blockers with chlorthalidone or hydrochlorothiazide - which is the better alternative? A meta-analysis. ARB, BP, CI, CTLD, WMD
36  2020 Development and validation of an advanced electrochemical sensor for the fast and cheap determination of hydrochlorothiazide in urine samples using the Monte-Carlo method for uncertainty evaluation. DPV, MCM, MWCNT
37  2020 Employment of Quality by Design Approach via Response Surface Methodology to Optimize and Develop Modified-release Formulation of Hydrochlorothiazide. MRT
38  2020 Enalapril protect human lymphocytes from genotoxicity of Hydrochlorothiazide. SCEs
39  2020 First Line CombinAtion Therapy in the Treatment of Stage II and III Hypertension (FLASH). BP, SBP
40  2020 Hierarchical modeling of blood pressure determinants and outcomes following valsartan treatment in hypertensive patients with known comorbidities: pooled analysis of six prospective real-world studies including 11,999 patients. BP, DBP
41  2020 Hydrochlorothiazide-induced systemic capillary leak. ---
42  2020 Ion Transport Modulators as Antimycobacterial Agents. TB
43  2020 Metabolic and Cardiovascular Effects of Switching Thiazides to Amlodipine in Hypertensive Patients With and Without Type 2 Diabetes (the Diuretics and Diabetes Control Study). CSGM, DiaDiC, eGFR, FMD, T2D
44  2020 Pharmacokinetics of Hydrochlorothiazide in Children: A Potential Surrogate for Renal Secretion Maturation. OAT1 and OAT3, PK
45  2020 Potential toxic effects of chlorination and UV/chlorination in the treatment of hydrochlorothiazide in the water. ---
46  2020 Risk of squamous cell carcinoma of the lip and cutaneous melanoma in older Australians using hydrochlorothiazide: A population-based case-control study. ORs
47  2020 Safety implications of combining ACE inhibitors with thiazides for the treatment of hypertensive patients. ACEI
48  2020 Sorting nexin 1 loss results in increased oxidative stress and hypertension. BP, HT, NOX, NT, ROS, RPT, SNX1
49  2020 The acute diuretic effects with low-doses of natural prenylated xanthones in rats. DGP, NTR, SHR, TDP, VEH
50  2020 The optimization of process analytical technology for the inline quantification of multiple drugs in fixed dose combinations during continuous processing. FDCs, PAT, PLS, RMP
51  2020 Use of hydrochlorothiazide and risk of nonmelanoma skin cancer in Koreans: a retrospective cohort study using administrative healthcare data. NMSC
52  2019 1,3,5,6-Tetrahydroxyxanthone, a natural xanthone, induces diuresis and saluresis in normotensive and hypertensive rats. NTR, SHR, THX, VEH
53  2019 7-(Diethylamino)coumarin-3-carboxylic acid as derivatization reagent for 405 nm laser-induced fluorescence detection: A case study for the analysis of sulfonamides by capillary electrophoresis. CTD, CTZ, LIF, MEKC
54  2019 A Randomized, Double-blinded, Controlled, Multicentre Phase III Study to Evaluate the Efficacy and Safety of Telmisartan /Amlodipine/Hydrochlorothiazide Compared to Telmisartan/Hydrochlorothiazide in Patients with Essential Hypertension. BP, ITT, mITT, PP
55  2019 Bio Pharmaceutics Classification System (BCS) Class IV Drug Nanoparticles: Quantum Leap to Improve Their Therapeutic Index. BCS, EDX
56  2019 Comparative efficacy and safety of chlorthalidone and hydrochlorothiazide-meta-analysis. CTLD
57  2019 Degradation of the diuretic hydrochlorothiazide by UV/Solar radiation assisted oxidation processes. AOPs
58  2019 Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. AA, BP, CTD, EA, PEAR-2
59  2019 Hydrochlorothiazide use and the risk of skin cancer in patients with hypertensive disorder: a nationwide retrospective cohort study from Korea. CI, HR, NMSC
60  2019 Hydrochlorothiazide-induced photosensitivity in a psoriasis patient following exposure to narrow-band ultraviolet B excimer therapy. NB, UV
61  2019 Multimodal Intervention to Improve Functional Status in Hypertensive Older Adults: A Pilot Randomized Controlled Trial. RCT
62  2019 Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K. hMATE1, hMATE2-K, hOAT1, hOAT3, hOCT2
63  2019 Severe Acquired Hypokalemic Paralysis in a Bodybuilder After Self-Medication With Triamterene/Hydrochlorothiazide. ECG
64  2019 Sex difference in kidney electrolyte transport II: impact of K+ intake on thiazide-sensitive cation excretion in male and female mice. AT1aR, HK, KO, NCC, NHE3, WT
65  2019 Unravelling the inhibitory and cytoprotective potential of diuretics towards amyloid fibrillation. ANS, CD, HL, HSA, INDP, TEM, ThT
66  2019 When a Diuretic Causes Pulmonary Oedema. ---
67  2019 Zinc deficiency induces hypertension by promoting renal Na+ reabsorption. BP, NCC
68  2018 A randomized, double-blind clinical trial of canrenone vs hydrochlorothiazide in addition to angiotensin II receptor blockers in hypertensive type 2 diabetic patients. ARBs, BMI, BP, eGFR, FPG, FPI, PPG, TC, TG
69  2018 Application of an LC-MS/MS method for the analysis of amlodipine, valsartan and hydrochlorothiazide in polypill for a bioequivalence study. AML, VAL
70  2018 Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies. BP, HTN, PEAR
71  2018 Challenges in Simultaneous Determination of Hydrochlorothiazide and Ramipril in Human Plasma: Application to a Bioequivalence Study. ISs
72  2018 Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison. CTD
73  2018 Fast and sensitive LC-MS/MS method for the simultaneous determination of lisinopril and hydrochlorothiazide in human plasma. ISs, LIS
74  2018 Fractal properties and morphological investigation of Nano hydrochlorothiazide is used to treat hypertension. ---
75  2018 Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients. PEAR-2
76  2018 Hydrochlorothiazide ameliorates polyuria caused by tolvaptan treatment of polycystic kidney disease in PCK rats. PKD
77  2018 Hydrochlorothiazide binding to human serum albumin induces some compactness in the molecular structure of the protein: A multi-spectroscopic and computational study. CD, FTIR, HSA, PSH
78  2018 Inflammation Due to Voriconazole-induced Photosensitivity Enhanced Skin Phototumorigenesis in Xpa-knockout Mice. ---
79  2018 Inhibition of Co-Crystallization of Olmesartan Medoxomil and Hydrochlorothiazide for Enhanced Dissolution Rate in Their Fixed Dose Combination. FDC, FTIR, HPMC, Olm, PXRD
80  2018 Lack of thiazide diuretic inhibition of agonist constriction of mouse mesenteric arterioles ex vivo. NCC, TZD, WT
81  2018 Multiple incidence of the prescription diuretic hydrochlorothiazide in compounded nutritional supplements. AAFs, WADA
82  2018 Na restriction activates epithelial Na channels in rat kidney through two mechanisms and decreases distal Na+ delivery. ENaC
83  2018 Preclinical evaluation of the diuretic and saluretic effects of (-)-epicatechin and the result of its combination with standard diuretics. EPI, NTR, SHR, VEH
84  2018 Probenecid Pre-treatment Downregulates the Kidney Cl-/HCO3- Exchanger (Pendrin) and Potentiates Hydrochlorothiazide-Induced Diuresis. Uvol
85  2018 Recurrent Hydrochlorothiazide-Induced Acute Respiratory Distress Syndrome Treated With Extracorporeal Membrane Oxygenation. ARDS, ECMO, vv-ECMO
86  2018 Renal sodium and magnesium reabsorption are not coupled in a mouse model of Gordon syndrome. CA-SPAK, DCT, NCC
87  2018 Simultaneous quantification of amiloride and hydrochlorothiazide in human plasma by liquid chromatography-tandem mass spectrometry. AMI
88  2018 Spironolactone is superior to hydrochlorothiazide for blood pressure control and arterial stiffness improvement: A prospective study. BP, cfPWV
89  2018 Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide. BP, GERA, PEAR
90  2018 The Impact of Thiazides and Potassium Citrate on Bone Mineral Density Evaluated by CT Scan in Stone Formers. BMD, NCCT
91  2017 A phase III, open-label, multicenter study to evaluate the safety and efficacy of long-term triple combination therapy with azilsartan, amlodipine, and hydrochlorothiazide in patients with essential hypertension. AEs, AML, AZL, BP
92  2017 A pilot study evaluating biomarker development for drug-induced chronic eczematous eruptions of aging individuals. CCB, CEEA
93  2017 A randomized controlled trial of the effects of hydrochlorothiazide on overactive bladder and idiopathic hypercalciuria. ---
94  2017 Ablation of the Cl-/HCO3- Exchanger Pendrin Enhances Hydrochlorothiazide-Induced Diuresis. ---
95  2017 Activation of human smooth muscle BK channels by hydrochlorothiazide requires cell integrity and the presence of BK beta1 subunit. SMCs
96  2017 Amplified nanostructure electrochemical sensor for simultaneous determination of captopril, acetaminophen, tyrosine and hydrochlorothiazide. AC, CA, DPID, SEM, TY, XRD
97  2017 Applying the methodology of Design of Experiments to stability studies: a Partial Least Squares approach for evaluation of drug stability. ---
98  2017 Chitosan microencapsulation of the dispersed phase of an O/W nanoemulsion to hydrochlorothiazide delivery. ---
99  2017 Comparison of efficacy and safety between benidipine and hydrochlorothiazide in fosinopril-treated hypertensive patients with chronic kidney disease: protocol for a randomised controlled trial. BP, CKD, eGFR
100  2017 Diuretic, natriuretic and potassium-sparing effect of nothofagin isolated from Leandra dasytricha (A. Gray) Cogn. leaves in normotensive and hypertensive rats. EALD, NOT, SHR