1 |
2022 |
Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties. |
AFM, EDS, SEM, SLA, TGA |
2 |
2022 |
Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug-resistant infections. |
AMPs |
3 |
2022 |
Brilacidin, a COVID-19 drug candidate, demonstrates broad-spectrum antiviral activity against human coronaviruses OC43, 229E, and NL63 through targeting both the virus and the host cell. |
HCoVs, HSPGs, SARS-CoV-2 |
4 |
2022 |
Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics. |
--- |
5 |
2022 |
Design, characterization and structure-function analysis of novel antimicrobial peptides based on the N-terminal CATH-2 fragment. |
--- |
6 |
2022 |
Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors. |
HDACi |
7 |
2022 |
Exploring the impact of the recombinant Escherichia coli strain on defensins antimicrobial activity: BL21 versus Origami strain. |
GFP, HD5, LAP |
8 |
2022 |
High-Throughput Identification of Epigenetic Compounds to Enhance Chicken Host Defense Peptide Gene Expression. |
HDAC |
9 |
2022 |
Host Defence Peptides: A Potent Alternative to Combat Antimicrobial Resistance in the Era of the COVID-19 Pandemic. |
AMR, WHO |
10 |
2022 |
Host defense peptide mimicking cyclic peptoid polymers exerting strong activity against drug-resistant bacteria. |
alpha-NNCAs, DBU |
11 |
2022 |
Host Defense Peptides at the Ocular Surface: Roles in Health and Major Diseases, and Therapeutic Potentials. |
--- |
12 |
2022 |
Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the Burkholderia cepacia Complex. |
Bcc, CLSM |
13 |
2022 |
Immune Modulation Ability of Hepcidin from Teleost Fish. |
AMP, dpi |
14 |
2022 |
Investigation of the Biocidal Performance of Multi-Functional Resin/Copper Nanocomposites with Superior Mechanical Response in SLA 3D Printing. |
AFM, EDS, SEM, SLA, TGA, UV |
15 |
2022 |
Modulation of outer membrane vesicle-based immune responses by cathelicidins. |
LPS, OMVs, TLR |
16 |
2022 |
Short Guanidinium-Functionalized Poly(2-oxazoline)s Displaying Potent Therapeutic Efficacy on Drug-Resistant Fungal Infections. |
POxs |
17 |
2022 |
SuPepMem: A database of innate immune system peptides and their cell membrane interactions. |
MD |
18 |
2022 |
Tibetan Pig-Derived Probiotic Lactobacillus amylovorus SLZX20-1 Improved Intestinal Function via Producing Enzymes and Regulating Intestinal Microflora. |
C. rodentium, E. coli, L. amylovorus, S. aureus, S. pullorum, S. typhimurium |
19 |
2021 |
Anti-mycobacterial activity evaluation of designed peptides: cryptic and database filtering based approach. |
MT |
20 |
2021 |
Antibiofilm activity of host defence peptides: complexity provides opportunities. |
--- |
21 |
2021 |
Antibiofilm peptides: overcoming biofilm-related treatment failure. |
--- |
22 |
2021 |
Butyrate and Forskolin Augment Host Defense, Barrier Function, and Disease Resistance Without Eliciting Inflammation. |
ICER |
23 |
2021 |
Characterisation of cell membrane interaction mechanisms of antimicrobial peptides by electrical bilayer recording. |
AMPs |
24 |
2021 |
Controlling Peptide Function by Directed Assembly Formation: Mechanistic Insights Using Multiscale Modeling on an Antimicrobial Peptide-Drug-Membrane System. |
AMPs, CG |
25 |
2021 |
Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption. |
--- |
26 |
2021 |
Covalent immobilization of DJK-5 peptide on porous titanium for enhanced antibacterial effects and restrained inflammatory osteoclastogenesis. |
--- |
27 |
2021 |
Cytotoxicity and antimicrobial activity of synthetic peptides alone or in combination with conventional antimicrobials against fish pathogenic bacteria. |
FFC, OTC, RBCs, TAP |
28 |
2021 |
Dimeric lipo-α/sulfono-γ-AA hybrid peptides as broad-spectrum antibiotic agents. |
--- |
29 |
2021 |
Discovery of natural products capable of inducing porcine host defense peptide gene expression using cell-based high throughput screening. |
--- |
30 |
2021 |
Effect of PEGylation on Host Defense Peptide Complexation with Bacterial Lipopolysaccharide. |
LPS, NMR |
31 |
2021 |
Enzymatically releasable polyethylene glycol - host defense peptide conjugates with improved activity and biocompatibility. |
MIC, MMPs, MRSA |
32 |
2021 |
Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies. |
AMR, CD, FICI, MD, MRSA |
33 |
2021 |
Evaluation of the effects of chlorhexidine digluconate with and without cBD103 or cCath against multidrug-resistant clinical isolates of Staphylococcus pseudintermedius. |
cBD103, cCath, CHX, MDR, MDR-SP, MIC |
34 |
2021 |
Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis. |
DSS |
35 |
2021 |
Host Defence Peptides in Diabetes Mellitus Type 2 Patients with Periodontal Disease. A Systematic Review. |
DM2, PD, SYRCLE |
36 |
2021 |
Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success. |
--- |
37 |
2021 |
Host defense peptides as immunomodulators: The other side of the coin. |
--- |
38 |
2021 |
Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action. |
AMPs, MDR |
39 |
2021 |
Immunomodulatory Properties of Host Defence Peptides in Skin Wound Healing. |
AMPs |
40 |
2021 |
Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B. |
--- |
41 |
2021 |
Interplay between membrane active host defense peptides and heme modulates their assemblies and in vitro activity. |
--- |
42 |
2021 |
Long-term exposure to particulate matter from air pollution alters airway β-defensin-3 and -4 and cathelicidin host defense peptides production in a murine model. |
CRAMP, PM |
43 |
2021 |
Mechanistic Fingerprinting Reveals Kinetic Signatures of Resistance to Daptomycin and Host Defense Peptides in Streptococcus mitis-oralis. |
CM, DAP-S, S. mitis-oralis |
44 |
2021 |
Modular Design of Membrane-Active Antibiotics: From Macromolecular Antimicrobials to Small Scorpionlike Peptidomimetics. |
MRSA |
45 |
2021 |
Multifaceted MRGPRX2: New insight into the role of mast cells in health and disease. |
MCs, MRGPRX2 |
46 |
2021 |
Murepavadin, a Small Molecule Host Defense Peptide Mimetic, Activates Mast Cells via MRGPRX2 and MrgprB2. |
MCs, MRGPRX2 |
47 |
2021 |
Nanodefensin-encased hydrogel with dual bactericidal and pro-regenerative functions for advanced wound therapy. |
HD5, ND, NDEFgel |
48 |
2021 |
Outer Membrane Vesicles Protect Gram-Negative Bacteria against Host Defense Peptides. |
OMVs |
49 |
2021 |
Platelets immune response against Mycobacterium tuberculosis infection. |
Mtb, TB |
50 |
2021 |
Protective Effects of Lactobacillus plantarum Lac16 on Clostridium perfringens Infection-Associated Injury in IPEC-J2 Cells. |
C. perfringens, L. plantarum, PRRs |
51 |
2021 |
Role of antimicrobial peptides in atopic dermatitis. |
AD, AMPs |
52 |
2021 |
Role of the Staphylococcus aureus Extracellular Loop of GraS in Resistance to Distinct Human Defense Peptides in PMN and Invasive Cardiovascular infections. |
EL, HA-MRSA, PMB, PMNs |
53 |
2021 |
SSTP1, a Host Defense Peptide, Exploits the Immunomodulatory IL6 Pathway to Induce Apoptosis in Cancer Cells. |
HDP |
54 |
2021 |
The cathelicidin CATH-2 efficiently neutralizes LPS- and E. coli-induced activation of porcine bone marrow derived macrophages. |
--- |
55 |
2021 |
γ-AApeptides as a New Class of Peptidomimetics: Design, Synthesis, and Applications. |
PNAs |
56 |
2020 |
Aggregation-Induced Emissive and Circularly Polarized Homogeneous Sulfono-gamma-AApeptide Foldamers. |
AIE, MRSA, TPE |
57 |
2020 |
Antimicrobial peptides: a promising strategy for lung cancer drug discovery? |
ACPs, AMPs |
58 |
2020 |
Antineoplastic Drug-Free Anticancer Strategy Enabled by Host-Defense-Peptides-Mimicking Synthetic Polypeptides. |
ACPP, DA-ACPP |
59 |
2020 |
Antiviral Activity of Chicken Cathelicidin B1 Against Influenza A Virus. |
CATHs, IAV, NA |
60 |
2020 |
Bioinspired Membrane-Disruptive Macromolecules as Drug-Free Therapeutics. |
--- |
61 |
2020 |
Cathelicidin Host Defense Peptides and Inflammatory Signaling: Striking a Balance. |
--- |
62 |
2020 |
Cryptic Host Defense Peptides: Multifaceted Activity and Prospects for Medicinal Chemistry. |
--- |
63 |
2020 |
Dimeric gamma-AApeptides With Potent and Selective Antibacterial Activity. |
--- |
64 |
2020 |
Does an Apple a Day Also Keep the Microbes Away? The Interplay Between Diet, Microbiota, and Host Defense Peptides at the Intestinal Mucosal Barrier. |
WSD |
65 |
2020 |
Enhancing the membrane activity of Piscidin 1 through peptide metallation and the presence of oxidized lipid species: Implications for the unification of host defense mechanisms at lipid membranes. |
OxPLs, PC, PG, UFAs |
66 |
2020 |
Enzymes as a Reservoir of Host Defence Peptides. |
--- |
67 |
2020 |
Evaluation of peptide-rich root extracts of Calliandria portoriscensis (Jacq.) Benth (Mimosaceae) for in vitro antimicrobial activity and brine shrimp lethality. |
CPr, IC50, LMW, TLC |
68 |
2020 |
Functional Insights From the Evolutionary Diversification of Big Defensins. |
PAV |
69 |
2020 |
Host Defence Cryptides from Human Apolipoproteins: Applications in Medicinal Chemistry. |
--- |
70 |
2020 |
Host defense peptide IDR-1002 associated with ciprofloxacin as a new antimicrobial and immunomodulatory strategy for dental pulp revascularization therapy. |
--- |
71 |
2020 |
Host Defense Peptides as Templates for Antifungal Drug Development. |
MDR |
72 |
2020 |
In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-betaNspe)6-NH2 and Lau-(Lys-betaNspe)6-NH2 Against PMA-Induced Acute Inflammation. |
PMA |
73 |
2020 |
Induction of Chicken Host Defense Peptides within Disease-Resistant and -Susceptible Lines. |
BMCs, CEFs, LPS |
74 |
2020 |
LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies. |
HDP, LC, SRM |
75 |
2020 |
Lipidation of Antimicrobial Peptides as a Design Strategy for Future Alternatives to Antibiotics. |
--- |
76 |
2020 |
Molecular and Biological Properties of Snakins: The Foremost Cysteine-Rich Plant Host Defense Peptides. |
AMPs |
77 |
2020 |
Molecular characterization, mRNA gene expression, and antimicrobial activity of 2 new cathelicidin genes in goose. |
--- |
78 |
2020 |
PMAP-36 reduces the innate immune response induced by Bordetella bronchiseptica-derived outer membrane vesicles. |
OMPLA, OMVs |
79 |
2020 |
Profiles of expression pattern and tissue distribution of host defense peptides genes in different chicken (Gallus gallus) breeds related to body weight. |
--- |
80 |
2020 |
Reptilian β-defensins: Expanding the repertoire of known crocodylian peptides. |
--- |
81 |
2020 |
Review: Examining the Natural Role of Amphibian Antimicrobial Peptide Magainin. |
AMPs |
82 |
2020 |
Self-Assembling, Ultrashort Peptide Gels as Antimicrobial Biomaterials. |
--- |
83 |
2020 |
Small Molecules with Membrane-Active Antibacterial Activity. |
--- |
84 |
2020 |
Sodium Butyrate Protects the Intestinal Barrier by Modulating Intestinal Host Defense Peptide Expression and Gut Microbiota after a Challenge with Deoxynivalenol in Weaned Piglets. |
DON, DON, SB |
85 |
2020 |
Strategies in Translating the Therapeutic Potentials of Host Defense Peptides. |
AMR |
86 |
2020 |
Synthetic Host Defense Peptides Inhibit Venezuelan Equine Encephalitis Virus Replication and the Associated Inflammatory Response. |
VEEV |
87 |
2020 |
The Human Host-Defense Peptide Cathelicidin LL-37 is a Nanomolar Inhibitor of Amyloid Self-Assembly of Islet Amyloid Polypeptide (IAPP). |
IAPP, T2D |
88 |
2020 |
The use of host defense peptides in root canal therapy in rats. |
--- |
89 |
2020 |
Toward the Discovery of Host-Defense Peptides in Plants. |
--- |
90 |
2020 |
Towards Robust Delivery of Antimicrobial Peptides to Combat Bacterial Resistance. |
AMPs, MDR |
91 |
2020 |
Transcriptomic and proteomic analyses of the venom and venom glands of Centruroides hirsutipalpus, a dangerous scorpion from Mexico. |
IGFBPs, NDBPs |
92 |
2020 |
Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense Peptides. |
IDR |
93 |
2019 |
Antibacterial Activity of Polymers: Discussions on the Nature of Amphiphilic Balance. |
--- |
94 |
2019 |
Antiviral Activities of Human Host Defense Peptides. |
--- |
95 |
2019 |
Bacterial resistance to antimicrobial peptides. |
AMPs |
96 |
2019 |
beta-Defensins: Farming the Microbiome for Homeostasis and Health. |
--- |
97 |
2019 |
Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action. |
--- |
98 |
2019 |
Characterization of a Cathelicidin from the Colubrinae Snake, Sinonatrix annularis. |
--- |
99 |
2019 |
Chicken CATH-2 Increases Antigen Presentation Markers on Chicken Monocytes and Macrophages. |
MRC1 |
100 |
2019 |
Cost-effective production of recombinant peptides in Escherichia coli. |
AMPs |