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Abbreviation : HDPs
Long Form : host defense peptides
No. Year Title Co-occurring Abbreviation
2022 Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties. AFM, EDS, SEM, SLA, TGA
2022 Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug-resistant infections. AMPs
2022 Brilacidin, a COVID-19 drug candidate, demonstrates broad-spectrum antiviral activity against human coronaviruses OC43, 229E, and NL63 through targeting both the virus and the host cell. HCoVs, HSPGs, SARS-CoV-2
2022 Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics. ---
2022 Design, characterization and structure-function analysis of novel antimicrobial peptides based on the N-terminal CATH-2 fragment. ---
2022 Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors. HDACi
2022 Exploring the impact of the recombinant Escherichia coli strain on defensins antimicrobial activity: BL21 versus Origami strain. GFP, HD5, LAP
2022 High-Throughput Identification of Epigenetic Compounds to Enhance Chicken Host Defense Peptide Gene Expression. HDAC
2022 Host Defence Peptides: A Potent Alternative to Combat Antimicrobial Resistance in the Era of the COVID-19 Pandemic. AMR, WHO
10  2022 Host defense peptide mimicking cyclic peptoid polymers exerting strong activity against drug-resistant bacteria. alpha-NNCAs, DBU
11  2022 Host Defense Peptides at the Ocular Surface: Roles in Health and Major Diseases, and Therapeutic Potentials. ---
12  2022 Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the Burkholderia cepacia Complex. Bcc, CLSM
13  2022 Immune Modulation Ability of Hepcidin from Teleost Fish. AMP, dpi
14  2022 Investigation of the Biocidal Performance of Multi-Functional Resin/Copper Nanocomposites with Superior Mechanical Response in SLA 3D Printing. AFM, EDS, SEM, SLA, TGA, UV
15  2022 Modulation of outer membrane vesicle-based immune responses by cathelicidins. LPS, OMVs, TLR
16  2022 Short Guanidinium-Functionalized Poly(2-oxazoline)s Displaying Potent Therapeutic Efficacy on Drug-Resistant Fungal Infections. POxs
17  2022 SuPepMem: A database of innate immune system peptides and their cell membrane interactions. MD
18  2022 Tibetan Pig-Derived Probiotic Lactobacillus amylovorus SLZX20-1 Improved Intestinal Function via Producing Enzymes and Regulating Intestinal Microflora. C. rodentium, E. coli, L. amylovorus, S. aureus, S. pullorum, S. typhimurium
19  2021 Anti-mycobacterial activity evaluation of designed peptides: cryptic and database filtering based approach. MT
20  2021 Antibiofilm activity of host defence peptides: complexity provides opportunities. ---
21  2021 Antibiofilm peptides: overcoming biofilm-related treatment failure. ---
22  2021 Butyrate and Forskolin Augment Host Defense, Barrier Function, and Disease Resistance Without Eliciting Inflammation. ICER
23  2021 Characterisation of cell membrane interaction mechanisms of antimicrobial peptides by electrical bilayer recording. AMPs
24  2021 Controlling Peptide Function by Directed Assembly Formation: Mechanistic Insights Using Multiscale Modeling on an Antimicrobial Peptide-Drug-Membrane System. AMPs, CG
25  2021 Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption. ---
26  2021 Covalent immobilization of DJK-5 peptide on porous titanium for enhanced antibacterial effects and restrained inflammatory osteoclastogenesis. ---
27  2021 Cytotoxicity and antimicrobial activity of synthetic peptides alone or in combination with conventional antimicrobials against fish pathogenic bacteria. FFC, OTC, RBCs, TAP
28  2021 Dimeric lipo-α/sulfono-γ-AA hybrid peptides as broad-spectrum antibiotic agents. ---
29  2021 Discovery of natural products capable of inducing porcine host defense peptide gene expression using cell-based high throughput screening. ---
30  2021 Effect of PEGylation on Host Defense Peptide Complexation with Bacterial Lipopolysaccharide. LPS, NMR
31  2021 Enzymatically releasable polyethylene glycol - host defense peptide conjugates with improved activity and biocompatibility. MIC, MMPs, MRSA
32  2021 Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies. AMR, CD, FICI, MD, MRSA
33  2021 Evaluation of the effects of chlorhexidine digluconate with and without cBD103 or cCath against multidrug-resistant clinical isolates of Staphylococcus pseudintermedius. cBD103, cCath, CHX, MDR, MDR-SP, MIC
34  2021 Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis. DSS
35  2021 Host Defence Peptides in Diabetes Mellitus Type 2 Patients with Periodontal Disease. A Systematic Review. DM2, PD, SYRCLE
36  2021 Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success. ---
37  2021 Host defense peptides as immunomodulators: The other side of the coin. ---
38  2021 Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action. AMPs, MDR
39  2021 Immunomodulatory Properties of Host Defence Peptides in Skin Wound Healing. AMPs
40  2021 Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B. ---
41  2021 Interplay between membrane active host defense peptides and heme modulates their assemblies and in vitro activity. ---
42  2021 Long-term exposure to particulate matter from air pollution alters airway β-defensin-3 and -4 and cathelicidin host defense peptides production in a murine model. CRAMP, PM
43  2021 Mechanistic Fingerprinting Reveals Kinetic Signatures of Resistance to Daptomycin and Host Defense Peptides in Streptococcus mitis-oralis. CM, DAP-S, S. mitis-oralis
44  2021 Modular Design of Membrane-Active Antibiotics: From Macromolecular Antimicrobials to Small Scorpionlike Peptidomimetics. MRSA
45  2021 Multifaceted MRGPRX2: New insight into the role of mast cells in health and disease. MCs, MRGPRX2
46  2021 Murepavadin, a Small Molecule Host Defense Peptide Mimetic, Activates Mast Cells via MRGPRX2 and MrgprB2. MCs, MRGPRX2
47  2021 Nanodefensin-encased hydrogel with dual bactericidal and pro-regenerative functions for advanced wound therapy. HD5, ND, NDEFgel
48  2021 Outer Membrane Vesicles Protect Gram-Negative Bacteria against Host Defense Peptides. OMVs
49  2021 Platelets immune response against Mycobacterium tuberculosis infection. Mtb, TB
50  2021 Protective Effects of Lactobacillus plantarum Lac16 on Clostridium perfringens Infection-Associated Injury in IPEC-J2 Cells. C. perfringens, L. plantarum, PRRs
51  2021 Role of antimicrobial peptides in atopic dermatitis. AD, AMPs
52  2021 Role of the Staphylococcus aureus Extracellular Loop of GraS in Resistance to Distinct Human Defense Peptides in PMN and Invasive Cardiovascular infections. EL, HA-MRSA, PMB, PMNs
53  2021 SSTP1, a Host Defense Peptide, Exploits the Immunomodulatory IL6 Pathway to Induce Apoptosis in Cancer Cells. HDP
54  2021 The cathelicidin CATH-2 efficiently neutralizes LPS- and E. coli-induced activation of porcine bone marrow derived macrophages. ---
55  2021 γ-AApeptides as a New Class of Peptidomimetics: Design, Synthesis, and Applications. PNAs
56  2020 Aggregation-Induced Emissive and Circularly Polarized Homogeneous Sulfono-gamma-AApeptide Foldamers. AIE, MRSA, TPE
57  2020 Antimicrobial peptides: a promising strategy for lung cancer drug discovery? ACPs, AMPs
58  2020 Antineoplastic Drug-Free Anticancer Strategy Enabled by Host-Defense-Peptides-Mimicking Synthetic Polypeptides. ACPP, DA-ACPP
59  2020 Antiviral Activity of Chicken Cathelicidin B1 Against Influenza A Virus. CATHs, IAV, NA
60  2020 Bioinspired Membrane-Disruptive Macromolecules as Drug-Free Therapeutics. ---
61  2020 Cathelicidin Host Defense Peptides and Inflammatory Signaling: Striking a Balance. ---
62  2020 Cryptic Host Defense Peptides: Multifaceted Activity and Prospects for Medicinal Chemistry. ---
63  2020 Dimeric gamma-AApeptides With Potent and Selective Antibacterial Activity. ---
64  2020 Does an Apple a Day Also Keep the Microbes Away? The Interplay Between Diet, Microbiota, and Host Defense Peptides at the Intestinal Mucosal Barrier. WSD
65  2020 Enhancing the membrane activity of Piscidin 1 through peptide metallation and the presence of oxidized lipid species: Implications for the unification of host defense mechanisms at lipid membranes. OxPLs, PC, PG, UFAs
66  2020 Enzymes as a Reservoir of Host Defence Peptides. ---
67  2020 Evaluation of peptide-rich root extracts of Calliandria portoriscensis (Jacq.) Benth (Mimosaceae) for in vitro antimicrobial activity and brine shrimp lethality. CPr, IC50, LMW, TLC
68  2020 Functional Insights From the Evolutionary Diversification of Big Defensins. PAV
69  2020 Host Defence Cryptides from Human Apolipoproteins: Applications in Medicinal Chemistry. ---
70  2020 Host defense peptide IDR-1002 associated with ciprofloxacin as a new antimicrobial and immunomodulatory strategy for dental pulp revascularization therapy. ---
71  2020 Host Defense Peptides as Templates for Antifungal Drug Development. MDR
72  2020 In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-betaNspe)6-NH2 and Lau-(Lys-betaNspe)6-NH2 Against PMA-Induced Acute Inflammation. PMA
73  2020 Induction of Chicken Host Defense Peptides within Disease-Resistant and -Susceptible Lines. BMCs, CEFs, LPS
74  2020 LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies. HDP, LC, SRM
75  2020 Lipidation of Antimicrobial Peptides as a Design Strategy for Future Alternatives to Antibiotics. ---
76  2020 Molecular and Biological Properties of Snakins: The Foremost Cysteine-Rich Plant Host Defense Peptides. AMPs
77  2020 Molecular characterization, mRNA gene expression, and antimicrobial activity of 2 new cathelicidin genes in goose. ---
78  2020 PMAP-36 reduces the innate immune response induced by Bordetella bronchiseptica-derived outer membrane vesicles. OMPLA, OMVs
79  2020 Profiles of expression pattern and tissue distribution of host defense peptides genes in different chicken (Gallus gallus) breeds related to body weight. ---
80  2020 Reptilian β-defensins: Expanding the repertoire of known crocodylian peptides. ---
81  2020 Review: Examining the Natural Role of Amphibian Antimicrobial Peptide Magainin. AMPs
82  2020 Self-Assembling, Ultrashort Peptide Gels as Antimicrobial Biomaterials. ---
83  2020 Small Molecules with Membrane-Active Antibacterial Activity. ---
84  2020 Sodium Butyrate Protects the Intestinal Barrier by Modulating Intestinal Host Defense Peptide Expression and Gut Microbiota after a Challenge with Deoxynivalenol in Weaned Piglets. DON, DON, SB
85  2020 Strategies in Translating the Therapeutic Potentials of Host Defense Peptides. AMR
86  2020 Synthetic Host Defense Peptides Inhibit Venezuelan Equine Encephalitis Virus Replication and the Associated Inflammatory Response. VEEV
87  2020 The Human Host-Defense Peptide Cathelicidin LL-37 is a Nanomolar Inhibitor of Amyloid Self-Assembly of Islet Amyloid Polypeptide (IAPP). IAPP, T2D
88  2020 The use of host defense peptides in root canal therapy in rats. ---
89  2020 Toward the Discovery of Host-Defense Peptides in Plants. ---
90  2020 Towards Robust Delivery of Antimicrobial Peptides to Combat Bacterial Resistance. AMPs, MDR
91  2020 Transcriptomic and proteomic analyses of the venom and venom glands of Centruroides hirsutipalpus, a dangerous scorpion from Mexico. IGFBPs, NDBPs
92  2020 Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense Peptides. IDR
93  2019 Antibacterial Activity of Polymers: Discussions on the Nature of Amphiphilic Balance. ---
94  2019 Antiviral Activities of Human Host Defense Peptides. ---
95  2019 Bacterial resistance to antimicrobial peptides. AMPs
96  2019 beta-Defensins: Farming the Microbiome for Homeostasis and Health. ---
97  2019 Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action. ---
98  2019 Characterization of a Cathelicidin from the Colubrinae Snake, Sinonatrix annularis. ---
99  2019 Chicken CATH-2 Increases Antigen Presentation Markers on Chicken Monocytes and Macrophages. MRC1
100  2019 Cost-effective production of recombinant peptides in Escherichia coli. AMPs