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Abbreviation : HEK
Long Form : human embryonic kidney
No. Year Title Co-occurring Abbreviation
2019 -254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-kappaB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children. ChIP-PCR, NF-kappaB, SNP, SRNS, TNF-alpha, TRPC6
2019 A High-Throughput System for Transient and Stable Protein Production in Mammalian Cells. CHO, PEPP
2019 Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G. AC6, AC6, ACs, GPCR, PTH, PTHR
2019 Analysis of Circular RNA Expression Profile in HEK 293T Cells Exposed to Ionizing Radiation. circRNAs, EGFR, IR, mTOR
2019 Calcium Imaging of Store-Operated Calcium (Ca2+) Entry (SOCE) in HEK293 Cells Using Fura-2. PM, STIM1
2019 Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal. CB2, CFA, PSNL
2019 Characterization of a third ghrelin receptor, GHS-R3a, in channel catfish reveals novel expression patterns and a high affinity for homologous ligand. ---
2019 Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism. OATP, WT
2019 Chk1 Inhibitor MK-8776 Restores the Sensitivity of Chemotherapeutics in P-glycoprotein Overexpressing Cancer Cells. ABC, Chk, MDR, P-gp
10  2019 Cross-linking, Immunoprecipitation and Proteomic Analysis to Identify Interacting Proteins in Cultured Cells. ER
11  2019 Development of alpha4 integrin DNA aptamer as a potential therapeutic tool for multiple sclerosis. SELEX
12  2019 Development of an alternating tangential flow (ATF) perfusion-based transient gene expression (TGE) bioprocess for universal influenza vaccine. ATF, TGE
13  2019 Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT). DA, DAT, MXE, SSRI, WT
14  2019 DNA profiling and in vitro cytotoxicity studies of tetrazolo[1,5-a]pyrimidine-based copper(II) complexes. CT-DNA, PBMC
15  2019 ETAR and protein kinase A pathway mediate ET-1 sensitization of TRPA1 channel: A molecular mechanism of ET-1-induced mechanical hyperalgesia. DRG, ET-1, ETAR, PKA, TRPA1
16  2019 Evaluation of cytotoxic potential, oral toxicity, genotoxicity, and mutagenicity of organic extracts of Pityrocarpa moniliformis. i.p, MN, TLC
17  2019 Exopolysaccharides synthesized by Bifidobacterium animalis subsp. lactis interact with TLR4 in intestinal epithelial cells. ---
18  2019 Exosomes Expressing Thyrotropin Receptor Attenuate Autoantibody-Mediated Stimulation of Cyclic Adenosine Monophosphate Production. cAMP, GD
19  2019 Genetically encoded FRET-based optical sensor for Hg2+ detection and intracellular imaging in living cells. E. coli, ECFP, MerFS
20  2019 High specificity of widely used phospho-tau antibodies validated using a quantitative whole-cell based assay. ---
21  2019 Human G protein-coupled receptor 30 is N-glycosylated and N-terminal domain asparagine 44 is required for receptor structure and activity. Ab, ER, ERK, GPCR, GPER, GPR30, N-domain, PM
22  2019 Immunity in Gilles de la Tourette-Syndrome: Results From a Cerebrospinal Fluid Study. CSF, GTS, MRI, OCB, rat
23  2019 Investigation of lipidomic perturbations in oxidatively stressed subcellular organelles and exosomes by asymmetrical flow field-flow fractionation and nanoflow ultrahigh performance liquid chromatography-tandem mass spectrometry. H2O2, OS, TG
24  2019 Label-Free Surface Protein Profiling of Extracellular Vesicles by an Electrokinetic Sensor. EGFR, NSCLC, sEVs
25  2019 LncRNA-H19 inhibits apoptosis of acute myeloid leukemia cells via targeting miR-29a-3p. AML, CCK-8, LEF-1, lncRNA, miR, TCF
26  2019 Mesenchymal Stem Cells Reduce Corneal Fibrosis and Inflammation Via Extracellular Vesicle-Mediated Delivery of miRNA. CSSC, EVs, miRNA
27  2019 Mink Enteritis Virus Infection Induces Mitochondrion-mediated Apoptosis by the Viral Nonstructural Protein 1. MEV, MEVB
28  2019 miR-545 promoted enterovirus 71 replication via directly targeting phosphatase and tensin homolog and tumor necrosis factor receptor-associated factor 6. EV71, miRNAs, mRNA, PTEN, RD, TRAF6
29  2019 Molecular signatures of cytotoxic effects in human embryonic kidney 293 cells treated with single and mixture of ochratoxin A and citrinin. CCNG1, CTN, DEGs, OTA, PDCD10
30  2019 Multiple mechanisms underlie increased cardiac late sodium current. CHO, hiPSC-CMs, PI3K
31  2019 Mutations in NaV1.5 Reveal Calcium-Calmodulin Regulation of Sodium Channel. CaM
32  2019 Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG. AQP4-IgG, NMOSD
33  2019 Nephroprotective activity of Combretum micranthum G. Don in cisplatin induced nephrotoxicity in rats: In-vitro, in-vivo and in-silico experiments. CM, CP, NF-kappaB, sEH
34  2019 New Insights Into the Role of Follicle-Stimulating Hormone in Sex Differentiation of the Protogynous Orange-Spotted Grouper, Epinephelus coioides. FSH
35  2019 Overview of a High-Throughput Pipeline for Streamlining the Production of Recombinant Proteins. OPPF
36  2019 Pharmacological characterization of the aminorex analogs 4-MAR, 4,4'-DMAR, and 3,4-DMAR. 3,4-DMAR, direx, 4,4'-DMAR, 4-MAR, DA, MDMA, NE, NPS
37  2019 Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP. AKT, MEF, PD, PINK1, Ser473
38  2019 Preparation and Characterization of Erythrocyte Membrane-Camouflaged Berberine Hydrochloride-Loaded Gelatin Nanoparticles. BH, RBGPs
39  2019 Purification and Characterization of Human Niemann-Pick C1 Protein. LDL, NPC1, NPC2
40  2019 Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins. BCRP, DABE, DDI, MATE, MATE1, P-gp
41  2019 SUMOylating Two Distinct Sites on the A-type Potassium Channel, Kv4.2, Increases Surface Expression and Decreases Current Amplitude. DPPL, KChIP, SUMO
42  2019 Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins. CHO
43  2019 Water channel activity of putative aquaporin-6 present in Aedes aegypti. AaAQP6, AQPs
44  2018 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in human cells. 5fC, DPCs
45  2018 A Polysaccharide Purified from Morchella conica Pers. Prevents Oxidative Stress Induced by H₂O₂ in Human Embryonic Kidney (HEK) 293T Cells. DPPH, MMP, MTT, NMCP-2, ROS
46  2018 A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2. ---
47  2018 An in Vitro Assay of hERG K + Channel Potency for a New EGFR Inhibitor FHND004. EGFR, hERG, LQTS, NSCLC, WT
48  2018 Anticardiolipin (aCL) in sera from periodontitis subjects activate Toll-like receptor 4 (TLR4). aCL, aCL, APS, beta2GPI, TLR's, TLR4
49  2018 Artificial Rod and Cone Photoreceptors with Human-Like Spectral Sensitivities. RHO
50  2018 Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation. LRRtm2
51  2018 Chaperone Activity and Dimerization Properties of Hsp90alpha and Hsp90beta in Glucocorticoid Receptor Activation by the Multiprotein Hsp90/Hsp70-Dependent Chaperone Machinery. GR, Hsp90
52  2018 Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques. Ig
53  2018 Cholesterol modulates the binding properties of human relaxin family peptide receptor 3 with its ligands. RXFP3
54  2018 Combining Optical Approaches with Human Inducible Pluripotent Stem Cells in G Protein-Coupled Receptor Drug Screening and Development. GPCRs, iPSC
55  2018 Conformationally rigid derivatives of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors. OTR, V1aR
56  2018 Construction and characterization of human embryonic kidney-(HEK)-293T cell overexpressing truncated alpha4 integrin. PCR, TITGA-4
57  2018 Dandelion Root Extract Induces Intracellular Ca2+ Increases in HEK293 Cells. DRE, ER, FRET, GFP, PH, PLC
58  2018 Dexmedetomidine relieves neuropathic pain by inhibiting hyperpolarization-activated cyclic nucleotide-gated currents in dorsal root ganglia neurons. CCI, DEX, DRG, HCN, NP
59  2018 Direct evidence for high affinity blockade of NaV1.6 channel subtype by huwentoxin-IV spider peptide, using multiscale functional approaches. HwTx-IV, TTX
60  2018 Effects of Landiolol in Lipopolysaccharide-Induced Acute Kidney Injury in Rats and In Vitro. AKI, LPS
61  2018 Fluorescence Imaging of Huntingtin mRNA Knockdown. HD, HTT, PNA
62  2018 Functional confirmation that the R1488* variant in SCN9A results in complete loss-of-function of Nav1.7. CIP
63  2018 G protein pathway suppressor 2 enhanced the renal large-conductance Ca2+-activated potassium channel expression via inhibiting ERK1/2 signaling pathway. GPS2, Po
64  2018 Genetic and functional analysis of the RYR1 mutation p.Thr84Met revealed a susceptibility to malignant hyperthermia. 4-CmC
65  2018 Genetic and functional characters of GRN p.T487I mutation in Taiwanese patients with atypical parkinsonian disorders. FTD, GRN
66  2018 Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies. GS, mAb, MSX, rHEK293E
67  2018 Glycoengineering of Mammalian Expression Systems on a Cellular Level. CHO
68  2018 Heterologous expression of three antigenic proteins from Angiostrongylus cantonensis: ES-7, Lec-5, and 14-3-3 in mammalian cells. CHO, EoM, NHS
69  2018 High-throughput metabolism-induced toxicity assays demonstrated on a 384-pillar plate. DMEs, EPA, HTS
70  2018 Involvement of Toll-like receptor 2 on human corneal epithelium during an infection of Pythium insidiosum. HCECs, MDMs, SEAP, TLR
71  2018 Kir2 inward rectification-controlled precise and dynamic balances between Kir2 and HCN currents initiate pacemaking activity. HCN2, Kir2.1
72  2018 Ligation of free HMGB1 to TLR2 in the absence of ligand is negatively regulated by the C-terminal tail domain. HMGB1, PBMCs, PGN, TLRs
73  2018 Linear Energy Transfer Modulates Radiation-Induced NF-kappa B Activation and Expression of its Downstream Target Genes. LET, NF-kappaB, RBE, RT-qPCR, UVA
74  2018 Mitochondria are physiologically maintained at close to 50 C. RC
75  2018 Molecularly imprinted polymers synthesized via template immobilization on fumed silica nanoparticles for the enrichment of phosphopeptides. MIPs, muMISPE, PTM
76  2018 Mu-Opioid Receptor Agonist Induces Kir3 Currents in Mouse Peripheral Sensory Neurons - Effects of Nerve Injury. CCI, DRG, MOR
77  2018 Nanoluciferase Reporter Gene System Directed by Tandemly Repeated Pseudo-Palindromic NFAT-Response Elements Facilitates Analysis of Biological Endpoint Effects of Cellular Ca2+ Mobilization. NanoLuc, RE, RLA, SOCE
78  2018 Natural and synthetic flavonoids, novel blockers of the volume-regulated anion channels, inhibit endothelial cell proliferation. BrdU, HUVEC, VRACs
79  2018 Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner. ---
80  2018 Non-Covalent Associates of siRNAs and AuNPs Enveloped with Lipid Layer and Doped with Amphiphilic Peptide for Efficient siRNA Delivery. DLS, GFP, TEM
81  2018 Oligomerization and Catalytic Parameters of Human UDP-Glucuronosyltransferase 1A10: Expression and Characterization of the Recombinant Protein. CHO, UGT
82  2018 Ondansetron blocks wild-type and p.F503L variant small-conductance Ca2+-activated K+ channels. diLQTS, KCNN, WT
83  2018 Pharmacokinetic-based prediction of real-life dosing of extended half-life clotting factor concentrates on hemophilia. ABRs, CFCs, CMs, EHL, Fc, Ig, PK, rF
84  2018 Phloretin as a Potent Natural TLR2/1 Inhibitor Suppresses TLR2-Induced Inflammation. IL, TLR2, TNF
85  2018 Protein kinase C epsilon mediates the inhibition of angiotensin II on the slowly activating delayed-rectifier potassium current through channel phosphorylation. Ang II, PKC, PMA
86  2018 Receptor-specific crosstalk between prostanoid E receptor 3 and bombesin receptor subtype 3. BRS-3, CHO, PGE2
87  2018 Recombinant Human Lysyl Oxidase-like 2 Secreted from Human Embryonic Kidney Cells Displays Complex and Acidic Glycans at All Three N-Linked Glycosylation Sites. hLOXL2
88  2018 Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer. IGF, IGFBPs, PAPP-A
89  2018 Selective plane illumination microscopy (SPIM) with time-domain fluorescence lifetime imaging microscopy (FLIM) for volumetric measurement of cleared mouse brain samples. FLIM, GFP, SPIM, SPIM-FLIM
90  2018 Stimulatory TSH-Receptor Antibodies and Oxidative Stress in Graves Disease. 4-HNE, GD, NOX2, ROS, TSHR
91  2018 Structure-based design of some isonicotinic acid hydrazide analogues as potential antitubercular agents. INH
92  2018 The Intracellular Cleavage Product of the NG2 Proteoglycan Modulates Translation and Cell-Cycle Kinetics via Effects on mTORC1/FMRP Signaling. CTF, FXS, ICD, OPCs
93  2018 The Phenotypic Effects of Exosomes Secreted from Distinct Cellular Sources: a Comparative Study Based on miRNA Composition. ---
94  2018 The role of unfolded protein response and ER-phagy in quantum dots-induced nephrotoxicity: an in vitro and in vivo study. CdTe, ER, QDs, UPR
95  2018 The Soluble Form of Toll-Like Receptor 2 Is Elevated in Serum of Multiple Sclerosis Patients: A Novel Potential Disease Biomarker. APR, CRP, EAE, HC, MS, RRMS, sTLR2, Th17, TLR, UTI
96  2018 TM9SF4 levels determine sorting of transmembrane domains in the early secretory pathway. ER, TMDs
97  2018 Triphenylstannyl((arylimino)methyl)benzoates with selective potency that induce G1 and G2/M cell cycle arrest and trigger apoptosis via ROS in human cervical cancer cells. ---
98  2018 Tritium-labeled agonists as tools for studying adenosine A2B receptors. A2BARs, CADO, CHO
99  2017 (E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its dual inhibitory effects on XOD and URAT1. BDEO, URAT1, XOD
100  2017 A High-Throughput Screening Assay for NKCC1 Cotransporter Using Nonradioactive Rubidium Flux Technology. HTS