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Abbreviation : HGFA
Long Form : hepatocyte growth factor activator
No. Year Title Co-occurring Abbreviation
2019 Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology. kbt, PS-SCL, SAR, TTSPs
2018 Circulating healing (CH) cells expressing BST2 are functionally activated by the injury-regulated systemic factor HGFA. BM, BST2, CH
2018 The impaired proteases and anti-proteases balance in Idiopathic Pulmonary Fibrosis. HAI, HAT, IPF, MMPs, PAI, PARs, PN, TIMPs
2017 HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert. FAPs, HGF, MuSCs
2017 Serum Glycoproteome Profiles for Distinguishing Intestinal Fibrosis from Inflammation in Crohn's Disease. CD, COMP
2015 Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma. HGF-MET
2015 Hepatocyte growth factor activator is a potential target proteinase for Kazal-type inhibitor in turkey (Meleagris gallopavo) seminal plasma. ---
2015 Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets. SAR, TTSPs
2014 Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer. RTKs, SPPS
10  2014 [Mechanism of bone marrow-derived mesenchymal stem cell-promoted apoptosis of hepatic stellate cells]. BMSC, HGF, HSCs
11  2012 Allosteric antibody inhibition of human hepsin protease. ---
12  2012 Hepatocyte growth factor activator inhibitor type 1 inhibits protease activity and proteolytic activation of human airway trypsin-like protease. HAI-1, HAT
13  2012 [Activation of hepatocyte growth factor-induced apoptosis in hepatic stellate cells]. BMSCs, ELISA, HGF, HGF, HSCs, PI, SMA
14  2011 Proteolytic activation of pro-macrophage-stimulating protein by hepsin. MSP
15  2010 Hepatocyte growth factor activator (HGFA). ---
16  2010 Hepatocyte growth factor activator (HGFA): a serine protease that links tissue injury to activation of hepatocyte growth factor. HGF
17  2010 Hepatocyte growth factor activator (HGFA): its regulation by protein C inhibitor. APC, hPCI-Tg, PCI
18  2010 Hepatocyte growth factor activator (HGFA): molecular structure and interactions with HGFA inhibitor-1 (HAI-1). HAI-1, KD1
19  2010 Hepatocyte growth factor activator (HGFA): pathophysiological functions in vivo. ---
20  2009 Hepatocyte growth factor activator is a serum activator of single-chain precursor macrophage-stimulating protein. MSP
21  2009 Unraveling the allosteric mechanism of serine protease inhibition by an antibody. ---
22  2008 Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases. KLKs
23  2008 Elevated serum concentrations of activated hepatocyte growth factor activator in patients with multiple myeloma. HGF
24  2008 Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer. HGF, HIF-1alpha
25  2008 Protein C inhibitor regulates hepatocyte growth factor activator-mediated liver regeneration in mice. APC, hPCI-Tg, NPCs, PCI, WT
26  2007 Structural insight into distinct mechanisms of protease inhibition by antibodies. ---
27  2006 Expression of hepatocyte growth factor activator inhibitor type 1 in endothelial cells. HAI-1, HGF/SF
28  2006 Serum hepatocyte growth factor activator inhibitor type I (HAI-I) and type 2 (HAI-2) in prostate cancer. BPH, HAI-1, HAI-I
29  2005 Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B. HAI-1B, HGF
30  2005 Serum hepatocyte growth factor activator (HGFA) in benign prostatic hyperplasia and prostate cancer. BPH, HGF
31  2005 [Effect of HAI-1 over-expression on in vitro growth and migration/motility of SW620 cells]. HAI-1
32  2004 Paradoxically enhanced immunoreactivity of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in cancer cells at the invasion front. HAI-1
33  2004 Regeneration of injured intestinal mucosa is impaired in hepatocyte growth factor activator-deficient mice. DSS, HGF
34  2004 [Hepatocyte growth factor (HGF) and its therapeutic applications]. HGF, SF
35  2003 Immunohistochemical localization of hepatocyte growth factor activator (HGFA) in developing mouse liver tissues. Heterogeneous distribution of HGFA protein. HGF, IHC
36  2002 Expression of a hepatocyte growth-factor activator protein in turkey (Meleagris gallopavo) deferent duct epithelial cells. ---
37  2002 Mouse hepatocyte growth factor (HGF) activator inhibitor type 2 lacking the first Kunitz domain potently inhibits the HGF activator. HAI-2, HGF
38  2002 Roles of hepatocyte growth factor activator (HGFA) and its inhibitor HAI-1 in the regeneration of injured gastrointestinal mucosa. HAI-1, HGF, SF
39  2001 Expression of hepatocyte growth factor activator and hepatocyte growth factor activator inhibitor type 1 in human hepatocellular carcinoma. HAI-1, HCC
40  2001 Identification of the substrates for plasma hyaluronan binding protein. PHBP, SDS-PAGE, uPA
41  2000 Genomic structure and chromosomal localization of the human hepatocyte growth factor activator inhibitor type 1 and 2 genes. BAC, HAI-1, KDs, LDL
42  2000 Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment. HAI-1, PB
43  2000 Mouse hepatocyte growth factor activator gene: its expression not only in the liver but also in the gastrointestinal tract. HGF
44  1999 Hepatocyte growth factor activator inhibitor type 2 lacking the first Kunitz-type serine proteinase inhibitor domain is a predominant product in mouse but not in human. dbEST, HAI-2, mHAI-2, RT-PCR
45  1998 Hepatocyte growth factor activator: a possible regulator of morphogenesis during fetal development of the rat gastrointestinal tract. HGF
46  1998 Structural organization and chromosomal localization of the human hepatocyte growth factor activator gene--phylogenetic and functional relationship with blood coagulation factor XII, urokinase, and tissue-type plasminogen activator. FXII
47  1997 Cloning of the cDNA for a mouse homologue of human PHBP: a novel hyaluronan-binding protein. PHBP
48  1997 Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation. cDNA, HGF, mRNA
49  1996 Purification and characterization of a novel hyaluronan-binding protein (PHBP) from human plasma: it has three EGF, a kringle and a serine protease domain, similar to hepatocyte growth factor activator. EGF, PHBP