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Abbreviation : HP
Long Form : 6-hydroxymethyl-7,8-dihydropterin
No. Year Title Co-occurring Abbreviation
2016 A Network of Conformational Transitions Revealed by Molecular Dynamics Simulations of the Binary Complex of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase with MgATP. HPPK
2009 Dynamics of the conformational transitions in the assembling of the Michaelis complex of a bisubstrate enzyme: a (15)N relaxation study of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. HPPK
2007 Mechanism of dihydroneopterin aldolase. NMR, equilibrium and transient kinetic studies of the Staphylococcus aureus and Escherichia coli enzymes. DHMP, DHNA, DHNP
2007 Structural basis for the aldolase and epimerase activities of Staphylococcus aureus dihydroneopterin aldolase. DHMP, DHNA, DHNP, SaDHNA
2007 Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics. CDC, EcHPPK, HPPK, YpHPPK
2006 Mechanism of dihydroneopterin aldolase: a molecular dynamics study of the apo enzyme and its product complex. DHNA
2006 Mechanism of dihydroneopterin aldolase: functional roles of the conserved active site glutamate and lysine residues. DHNA, DHNP, EcDHNA, HPO, SaDHNA
2006 Mechanism of the conformational transitions in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by NMR spectroscopy. DMHP, HPPK
2005 Is the critical role of loop 3 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase in catalysis due to loop-3 residues arginine-84 and tryptophan-89? Site-directed mutagenesis, biochemical, and crystallographic studies. HPPK
10  2004 Essential roles of a dynamic loop in the catalysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. HPPK
11  2004 Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. HPPK, HPPP
12  2003 Catalytic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: site-directed mutagenesis and biochemical studies. HPPK
13  2003 Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: crystallographic studies. HPPK
14  2001 Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies. HPPK
15  2001 Structure and dynamics of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. HPPK
16  2000 Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution. HPPK
17  1999 Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents. HPPK