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Abbreviation : HP
Long Form : haloperidol
No. Year Title Co-occurring Abbreviation
2019 Catechol-o-methyltransferase inhibitor tolcapone improves learning and memory in naive but not in haloperidol challenged rats. COMT, CR, TCP, TWAA, UCR
2018 Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice. CAF, COX, EPS, NPX, PD, PGs
2017 Antioxidant effects of rice bran oil mitigate repeated haloperidol-induced tardive dyskinesia in male rats. CAT, GPx, MDA, RBO, SOD, TD
2017 Haloperidol undermining gastroparesis symptoms (HUGS) in the emergency department. ED, HUGS, LOS, ME
2016 HALOPERIDOL MODULATES IONIC TRANSPORT OF CHARA CORALLINA CELLS. ---
2016 Hydrogen Bonding: Between Strengthening the Crystal Packing and Improving Solubility of Three Haloperidol Derivatives. DHP, DP
2016 Possible biomarkers modulating haloperidol efficacy and/or tolerability. ---
2014 Facile stripping voltammetric determination of haloperidol using a high performance magnetite/carbon nanotube paste electrode in pharmaceutical and biological samples. SEM
2014 Solid lipid nanoparticles for nose to brain delivery of haloperidol: in vitro drug release and pharmacokinetics evaluation. i.n, SLNs
10  2013 Determination of oxidative stress and activities of antioxidant enzymes in guinea pigs treated with haloperidol. FR, FRAP, GR, GST, SOD
11  2013 Effect of Jobelyn on intruder- and isolation-induced aggressive behavior in mice. 5-HT, FL, JB, MS, PCPA
12  2013 Haloperidol cytotoxicity and its relation to oxidative stress. ---
13  2012 Anti-aggressive activity of methyl jasmonate and the probable mechanism of its action in mice. 5-HT, FL, MJ, PCPA
14  2011 Alpha-phenyl-N-tert-butylnitrone prevents oxidative stress in a haloperidol-induced animal model of tardive dyskinesia: investigating the behavioural and biochemical changes. AIF, PBN, TD, VCMs
15  2011 Structure-activity study to develop cationic lipid-conjugated haloperidol derivatives as a new class of anticancer therapeutics. HP-C8, SR
16  2011 The styrene metabolite, phenylglyoxylic acid, induces striatal-motor toxicity in the rat: influence of dose escalation/reduction over time. PGA, VCM
17  2009 Transdermal delivery of haloperidol by proniosomal formulations with non-ionic surfactants. HLB
18  2008 Potentially adverse interactions between haloperidol and valerian. AST, CAT, DCFH, delta-ALA-D, SOD
19  2007 Effects of haloperidol and its pyridinium metabolite on plasma membrane permeability and fluidity in the rat brain. ---
20  2007 Formulation development of transdermal dosage forms: quantitative structure-activity relationship model for predicting activities of terpenes that enhance drug penetration through human skin. HSPE, MLR, PG, QSAR
21  2007 Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells. ---
22  2007 MIF-1 and its peptidomimetic analogs attenuate haloperidol-induced vacuous chewing movements and modulate apomorphine-induced rotational behavior in 6-hydroxydopamine-lesioned rats. MIF-1, PD, PLG, TD, VCMs
23  2006 Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites. RHP
24  2006 Determination of haloperidol and reduced haloperidol in human serum by liquid chromatography after fluorescence labeling based on the Suzuki coupling reaction. DPA, HPLC, RHP, TDM
25  2006 Iontophoretic transdermal delivery of haloperidol. ---
26  2006 Limonene GP1/PG organogel as a vehicle in transdermal delivery of haloperidol. PG, TDD
27  2004 Electron spin resonance spectroscopy reveals alpha-phenyl-N-tert-butylnitrone spin-traps free radicals in rat striatum and prevents haloperidol-induced vacuous chewing movements in the rat model of human tardive dyskinesia. DA, ESR, PBN, TD, VCM
28  2003 Effect of Withania somnifera root extract on haloperidol-induced orofacial dyskinesia: possible mechanisms of action. SOD, VCMs
29  2003 Haloperidol, but not clozapine, produces dramatic catalepsy in delta9-THC-treated rats: possible clinical implications. CLOZ, Delta9-THC
30  2003 Haloperidol-induced dyskinesia is associated with striatal NO synthase suppression: reversal with olanzapine. cGMP, DA, NO, OLZ, TD, VCMs
31  2003 Oxide terpenes as human skin penetration enhancers of haloperidol from ethanol and propylene glycol and their modes of action on stratum corneum. PG
32  2002 Metabolic studies on haloperidol and its tetrahydropyridinyl dehydration product (HPTP) in C57BL/6 mouse brain preparations. HPTP
33  2002 Terpenes in ethanol: haloperidol permeation and partition through human skin and stratum corneum changes. DSC, FT-IR, MP, SC
34  2002 Terpenes in propylene glycol as skin-penetration enhancers: permeation and partition of haloperidol, Fourier transform infrared spectroscopy, and differential scanning calorimetry. PG, SC
35  2001 Analysis of the metabolism of haloperidol and its neurotoxic pyridinium metabolite in patients with drug-induced parkinsonism. ESRS
36  2001 Effects of dopamine and dopamine-active compounds on oxytocin and vasopressin production in rat neurohypophyseal tissue cultures. APM, CPZ, DA, NH, OT, PLG, SP, VP
37  2000 Analysis of the metabolism of haloperidol (HP) and its neurotoxic pyridinium metabolite (HPP+) in patients with drug-induced parkinsonism. ---
38  2000 Haloperidol-induced neurotoxicity--possible implications for tardive dyskinesia. NAC, TD
39  1999 Determination of 1-methyl-1,2,3,4-tetrahydroisoquinoline in mouse brain after treatment with haloperidol by gas chromatography-selected ion monitoring. 1MeTIQ
40  1999 Enzyme-catalyzed bioactivation of cyclic tertiary amines to form potential neurotoxins. MPTP, RHP
41  1999 p-Fluorophenylglycine in the urine of baboons treated with HPTP, the tetrahydropyridine analog of haloperidol. alpha-PG, DA, p-FBPA, p-FPA, p-FPG, p-FPGA, TD
42  1999 Role of CYP3A in haloperidol N-dealkylation and pharmacokinetics in rats. FBPA, TAO
43  1999 Trace analysis of haloperidol and its chiral metabolite in plasma by capillary electrophoresis. ---
44  1998 Chirality of reduced haloperidol in humans. RHP
45  1998 Effects of haloperidol metabolites on neurotransmitter uptake and release: possible role in neurotoxicity and tardive dyskinesia. HPTP
46  1998 Haloperidol potentiates the EEG slowing of MK-801 despite blocking its motor effects: implications for the PCP model of schizophrenia. ---
47  1998 Induction of NF-kappaB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: suppression of NF-kappaB and neuroprotection by antioxidants. ---
48  1998 Induction of reactive oxygen species in neurons by haloperidol. ROS
49  1998 The thymolytic effect of cocaine and monoaminergic drugs in the mouse. AM, CC, DA, EN
50  1998 [Pharmacokinetics of haloperidol in patients on hemodialysis]. HD
51  1997 Metabolism of haloperidol to pyridinium species in patients receiving high doses intravenously: is HPTP an intermediate? ---
52  1997 Two pyridinium metabolites of haloperidol are present in the brain of patients at post-mortem. ---
53  1996 Dopamine receptor binding of 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)- 4-oxobutyl]-1,2,3,6-tetrahydropyridine (HPTP), an intermediate metabolite of haloperidol. ---
54  1996 Effect of a pyridinium metabolite derived from haloperidol on the activities of striatal tyrosine hydroxylase in freely moving rats. 5-HIAA, DOPA, TH
55  1996 Haloperidol and its tetrahydropyridine derivative (HPTP) are metabolized to potentially neurotoxic pyridinium species in the baboon. HPTP, RHPTP
56  1996 Haloperidol inhibits neuronal nitric oxide synthase activity by preventing electron transfer. nNOS
57  1996 Long-term treatment with the tetrahydropyridine analog (HPTP) of haloperidol influences dopamine ligand binding in baboon brain. An [123I]iodobenzamide (IBZM) SPECT study. HPTP, IBZM, MPTP, SPECT
58  1996 Significantly higher plasma haloperidol level during cotreatment with carbamazepine may herald cardiac change. CBZ, QTc
59  1996 Studies on the conversion of haloperidol and its tetrahydropyridine dehydration product to potentially neurotoxic pyridinium metabolites by human liver microsomes. ---
60  1995 Studies on the metabolism of haloperidol (HP): the role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following ip administration of HP. ---
61  1995 The drug-drug interaction effects of haloperidol on plasma carbamazepine levels. CBZ
62  1994 1-Methyl-4-phenylpyridinium-like neurotoxicity of a pyridinium metabolite derived from haloperidol: cell culture and neurotransmitter uptake studies. ---
63  1994 Metabolic studies on haloperidol and its tetrahydropyridine analog in C57BL/6 mice. API, HPTP, MPTP, RHP
64  1994 Nonlinear relationship between circulating concentrations of reduced haloperidol and haloperidol: evaluation of possible mechanisms. ---
65  1993 The role of brain dopamine in response initiation: effects of haloperidol and regionally specific dopamine depletions on the local rate of instrumental responding. FR5, IRT
66  1993 Vacuous jaw movements induced by sub-chronic administration of haloperidol: interactions with scopolamine. ---
67  1992 Determination of the pyridinium metabolite derived from haloperidol in brain tissue, plasma and urine by high-performance liquid chromatography with fluorescence detection. ---
68  1992 Stereospecific reduction of haloperidol in human tissues. RHP
69  1991 Haloperidol and nucleus accumbens dopamine depletion suppress lever pressing for food but increase free food consumption in a novel food choice procedure. ---
70  1991 The measurement of haloperidol and reduced haloperidol in neonatal hair as an index of placental transfer of maternal haloperidol. RHP
71  1990 Ethanol reduces tolerance, sensitization, and up-regulation of D2-receptors after subchronic haloperidol. EtOH
72  1989 Carbamazepine compared to haloperidol in acute mania. CBZ, EPS
73  1987 In vitro evaluation of radioiodinated butyrophenones as radiotracer for dopamine receptor study. 2'-IHP, 2'-ISP, 2'-ITP, 4-ISP, SP
74  1986 Different effects of haloperidol and extinction on instrumental behaviours. ---
75  1985 The effect of dopamine receptor agonist treatment on haloperidol-induced supersensitivity in mice. DA
76  1979 Effects of two neuroleptic drugs on focal somatoparietal rhythms in free awake cats. CPZ
77  1978 The effect of agents stimulating dopaminergic system on incorporation of exogenous adenine into striate body slices of the rat. AMD, APM, DA, DMAD
78  1978 The effect of drugs stimulating central dopaminergic system on transformation of exogenous adenine into c-AMP. AMD, APM, DA, DMAD
79  1977 The effect of apomorphine, amantadine and dimethylaminoadamantane on the level of cyclic AMP in the rat striatum. AMD, APM, cAMP, DA, DMAD