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[Related PubMed/MEDLINE]
Total Number of Papers: 748
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| Abbreviation |
: HSV-TK |
| Long Form |
: herpes simplex virus thymidine kinase |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2022 |
Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases. |
GCV, NSCLC, SHED |
| 2 |
2022 |
Hypoxia-directed tumor targeting of CRISPR-Cas9 and HSV-TK suicide gene therapy using lipid nanoparticles. |
CMV, HIF-1, HRE, LNPs |
| 3 |
2022 |
Improving the Safety of Mesenchymal Stem Cell-Based Ex Vivo Therapy Using Herpes Simplex Virus Thymidine Kinase. |
GCV, MSCs, SAEs, VGCV |
| 4 |
2022 |
In vitro assessment of an engineered tBID-based safety switch system in human T lymphocytes. |
iCasp9, TMP |
| 5 |
2022 |
Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth. |
GCV, SHED, SHEDTK |
| 6 |
2022 |
Preclinical gene therapy in glioblastoma multiforme: Using olfactory ensheathing cells containing a suicide gene. |
GBM, GCV, OEC-tks, OECs |
| 7 |
2022 |
Selective Depletion of Adult GFAP-Expressing Tanycytes Leads to Hypogonadotropic Hypogonadism in Males. |
GCV, GFAP, GnRH, NSPCs, SGZ, SVZ |
| 8 |
2022 |
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells. |
GCV |
| 9 |
2021 |
An AAV gene therapy computes over multiple cellular inputs to enable precise targeting of multifocal hepatocellular carcinoma in mice. |
AAV |
| 10 |
2021 |
An Efficient Strategy for Obtaining Mutants by Targeted Gene Deletion in Ophiostoma novo-ulmi. |
DED, HR, NHEJ, TFs, WT |
| 11 |
2021 |
Cytopathic effects and local immune responses in repeated neoadjuvant HSV-tk + ganciclovir gene therapy for prostate cancer. |
GCV, GT, LI, PCa, ssDNA |
| 12 |
2021 |
Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B. |
HBV, iC9, S-CAR, TCR |
| 13 |
2021 |
Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons. |
ImmTAC, TCRs |
| 14 |
2021 |
Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP). |
ABC, BCRP, GCV, MRPs, MTX |
| 15 |
2021 |
Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy. |
GCV, GM-CSF, iCasp9, iPSCs |
| 16 |
2021 |
Intracerebral Administration of Autologous Mesenchymal Stem Cells as HSV-TK Gene Vehicle for Treatment of Glioblastoma Multiform: Safety and Feasibility Assessment. |
GBM, MSCs, OS, PFS |
| 17 |
2021 |
Iron Oxide Nanoparticles Promote Cx43-Overexpression of Mesenchymal Stem Cells for Efficient Suicide Gene Therapy during Glioma Treatment. |
Cx43, GCV, GJIC, MFIONs, MSCs |
| 18 |
2021 |
Neural Progenitor Cells Expressing Herpes Simplex Virus-Thymidine Kinase for Ablation Have Differential Chemosensitivity to Brivudine and Ganciclovir. |
BVDU, GCV, NPC, SCI |
| 19 |
2021 |
Poly(ethylene glycol)-Poly(beta-amino ester)-Based Nanoparticles for Suicide Gene Therapy Enhance Brain Penetration and Extend Survival in a Preclinical Human Glioblastoma Orthotopic Xenograft Model. |
ePBAE, GBM, NPs, PEG-PBAE |
| 20 |
2021 |
Polymeric Nanovectors Incorporated with Ganciclovir and HSV-tk Encoding Plasmid for Gene-Directed Enzyme Prodrug Therapy. |
epsilon-CL, GCV, GCV-PCL, GDEPT |
| 21 |
2020 |
A human Myogenin promoter modified to be highly active in alveolar rhabdomyosarcoma drives an effective suicide gene therapy. |
ARMS |
| 22 |
2020 |
Complete regression of metastatic de-differentiated liposarcoma with engineered mesenchymal stromal cells with dTRAIL and HSV-TK. |
DDLPS, dTRAIL, GCV, MSC, PDCs |
| 23 |
2020 |
Demonstration of anti-tumour bystander killing with prodrug-preloaded suicide gene-engineered tumour cells: a potential improvement for cancer therapeutics. |
GCV |
| 24 |
2020 |
Engineering and Characterization of Oncolytic Vaccinia Virus Expressing Truncated Herpes Simplex Virus Thymidine Kinase. |
OVV |
| 25 |
2020 |
Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect. |
GCV, hiPSCs |
| 26 |
2020 |
Implication of in vivo circulating fibrocytes ablation in experimental pulmonary hypertension murine model. |
alpha-SMA, CF, PH |
| 27 |
2020 |
Improvement of the dP-nucleoside-mediated herpes simplex virus thymidine kinase negative-selection system by manipulating dP metabolism genes. |
--- |
| 28 |
2020 |
Selective Elimination of NG2-Expressing Hair Follicle Stem Cells Exacerbates the Sensitization Phase of Contact Dermatitis in a Transgenic Rat Model. |
GCV, HFSCs, Tg |
| 29 |
2020 |
Suicide Gene Therapy Mediated with Exosomes Produced by Mesenchymal Stem/Stromal Cells Stably Transduced with HSV Thymidine Kinase. |
GCV, MSCs |
| 30 |
2019 |
Cell-based interferon gene therapy using proliferation-controllable, interferon-releasing mesenchymal stem cells. |
IFN-gamma |
| 31 |
2019 |
Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice. |
FC, TAA |
| 32 |
2019 |
Epithelial ovarian cancer: feasibility of image-guided intratumoral radiofrequency hyperthermia-enhanced direct gene therapy. |
PBS, RFH |
| 33 |
2019 |
Human embryonic stem cell-derived cardiomyocyte therapy in mouse permanent ischemia and ischemia-reperfusion models. |
ESC-CM, ESC-Rep-CMs, Fluc, GFP, IR, LAD, LVEF, LVFS, PI |
| 34 |
2019 |
Human Genomic Safe Harbors and the Suicide Gene-Based Safeguard System for iPSC-Based Cell Therapy. |
GSHs, hiPSCs |
| 35 |
2019 |
Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma. |
EGFR, GBM, GCV, GFP, valGCV |
| 36 |
2019 |
Nonviral polymeric nanoparticles for gene therapy in pediatric CNS malignancies. |
AT/RT, MB, PBAE |
| 37 |
2019 |
Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells. |
LV, LV-TK |
| 38 |
2019 |
Rapid Regulation of Human Mesenchymal Stem Cell Proliferation Using Inducible Caspase-9 Suicide Gene for Safe Cell-Based Therapy. |
GCV, iC9, Nluc |
| 39 |
2019 |
Suicide Gene Therapy Against Malignant Gliomas by the Local Delivery of Genetically Engineered Umbilical Cord Mesenchymal Stem Cells as Cellular Vehicles. |
GBM, GCV, MSCs |
| 40 |
2019 |
Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies. |
AAVP, GCV, TNF |
| 41 |
2018 |
A Herpes Simplex Virus Thymidine Kinase-Induced Mouse Model of Hepatocellular Carcinoma Associated with Up-Regulated Immune-Inflammatory-Related Signals. |
GCV, GO, GSEA, HCC |
| 42 |
2018 |
Cancer Suicide Gene Therapy with TK.007. |
GCV, SGT |
| 43 |
2018 |
Cholangiocarcinoma: molecular imaging-guided radiofrequency hyperthermia-enhanced intratumoral herpes simplex virus thymidine kinase gene therapy. |
CBD, GCV, GFP, RFH |
| 44 |
2018 |
Engineering functional BMP-2 expressing teratoma-derived fibroblasts for enhancing osteogenesis. |
ALP, BMP-2, GCV, TDF |
| 45 |
2018 |
Graphene oxide-hydroxyapatite nanocomposites effectively deliver HSV-TK suicide gene to inhibit human breast cancer growth. |
GO-HAp |
| 46 |
2018 |
Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy. |
MSC, TRAIL |
| 47 |
2018 |
Introduction of Exogenous HSV-TK Suicide Gene Increases Safety of Keratinocyte-Derived Induced Pluripotent Stem Cells by Providing Genetic "Emergency Exit" Switch. |
ES, GCV, iPS |
| 48 |
2018 |
Linking a cell-division gene and a suicide gene to define and improve cell therapy safety. |
--- |
| 49 |
2018 |
New Plasmids for Fusarium Transformation Allowing Positive-Negative Selection and Efficient Cre-loxP Mediated Marker Recycling. |
FdU, PKI |
| 50 |
2018 |
Noninvasive and Local Delivery of Adenoviral-Mediated Herpes Simplex Virus Thymidine Kinase to Treat Glioma Through Focused Ultrasound-Induced Blood-Brain Barrier Opening in Rats. |
Ad-EGFP, BBB, FUS, GCV |
| 51 |
2018 |
Orthotopic hepatic cancer: radiofrequency hyperthermia-enhanced intratumoral herpes simplex virus-thymidine kinase gene therapy. |
GCV, PBS, RFH |
| 52 |
2018 |
Osteonectin Promoter-Mediated Suicide Gene Therapy of Prostate Cancer. |
GCV |
| 53 |
2018 |
Regulation of proliferation and functioning of transplanted cells by using herpes simplex virus thymidine kinase gene in mice. |
GCV |
| 54 |
2018 |
Suicide Gene Therapy for Oral Squamous Cell Carcinoma. |
GCV |
| 55 |
2017 |
A Modified Adenovirus Vector-Mediated Antibody Screening Method Identifies EphA2 as a Cancer Target. |
GCV, mAbs |
| 56 |
2017 |
A Safety Checkpoint to Eliminate Cancer Risk of the Immune Evasive Cells Derived from Human Embryonic Stem Cells. |
hESCs, hu-mice |
| 57 |
2017 |
Engineering of Systematic Elimination of a Targeted Chromosome in Human Cells. |
GCV |
| 58 |
2017 |
Genetic studies in mice directly link oocytes produced during adulthood to ovarian function and natural fertility. |
GCV, OSCs, Stra8 |
| 59 |
2017 |
Genetically Engineered Multilineage-Differentiating Stress-Enduring Cells as Cellular Vehicles against Malignant Gliomas. |
GCV, Muse |
| 60 |
2017 |
HSVtk/GCV system on hepatoma carcinoma cells: Construction of the plasmid pcDNA3.1‑pAFP-TK and targeted killing effect. |
AFP, GCV |
| 61 |
2017 |
Regulation of HSVtk gene by endogenous microRNA-122a in liver cell lines as suicide gene therapy. |
Ad, GCV |
| 62 |
2017 |
Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene. |
GCV |
| 63 |
2017 |
STAT3/NF-kappaB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer. |
CSCs, TNBC |
| 64 |
2016 |
A non-viral suicide gene delivery system traversing the blood brain barrier for non-invasive glioma targeting treatment. |
BBB, GBM, PEG, PPA NPs |
| 65 |
2016 |
A Positive Selection for Nucleoside Kinases in E. coli. |
AZT |
| 66 |
2016 |
Antitumor activity of combined endostatin and thymidine kinase gene therapy in C6 glioma models. |
ES, GCV, HUVECs, IRES, MVD |
| 67 |
2016 |
Combined delivery of temozolomide and the thymidine kinase gene for treatment of glioblastoma. |
R7L10, TMZ |
| 68 |
2016 |
Development of a cancer-marker activated enzymatic switch from the herpes simplex virus thymidine kinase. |
AZT, C-TAD, GDEPT, TICKLE |
| 69 |
2016 |
Elimination of proliferating cells from CNS grafts using a Ki67 promoter-driven thymidine kinase. |
NPC, PSC |
| 70 |
2016 |
Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene. |
GCV, hPSCs, iPSCs |
| 71 |
2016 |
Exogenous p53 and ASPP2 expression enhances rAdV-TK/ GCV-induced death in hepatocellular carcinoma cells lacking functional p53. |
GCV, HCC, rAdv |
| 72 |
2016 |
Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma. |
APOE, HCC, PEPCK, PRT, Rz |
| 73 |
2016 |
Repression of telomerase gene promoter requires human-specific genomic context and is mediated by multiple HDAC1-containing corepressor complexes. |
BAC, HDAC, hTERT, NuRD |
| 74 |
2016 |
Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase. |
ENBT1, GCV, GFP, HeLa, MDCKII |
| 75 |
2016 |
Screening glioma stem cells in U251 cells based on the P1 promoter of the CD133 gene. |
CD, GSCs |
| 76 |
2016 |
Suppression of neointima formation by targeting beta-catenin/TCF pathway. |
GCV, TCF |
| 77 |
2016 |
Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer. |
AAVP, AVPC, PDX |
| 78 |
2016 |
The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction. |
i.e. intravenous |
| 79 |
2016 |
Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes. |
AAVP, IBC |
| 80 |
2016 |
Tumor-specific promoter-driven adenoviral therapy for insulinoma. |
INSM1, NE, NRSEs |
| 81 |
2015 |
A GSDMB enhancer-driven HSV thymidine kinase-expressing vector for controlling occult peritoneal dissemination of gastric cancer cells. |
GC, PD |
| 82 |
2015 |
A New Approach in Gene Therapy of Glioblastoma Multiforme: Human Olfactory Ensheathing Cells as a Novel Carrier for Suicide Gene Delivery. |
GBM, MAP2, OECs, S100beta |
| 83 |
2015 |
Combined antitumor gene therapy with herpes simplex virus-thymidine kinase and short hairpin RNA specific for mammalian target of rapamycin. |
GCV, mTOR, rAAV, shRNA |
| 84 |
2015 |
Combined enzyme/prodrug treatment by genetically engineered AT-MSC exerts synergy and inhibits growth of MDA-MB-231 induced lung metastases. |
5-FC, AT-MSC, CD, GCV, MSC |
| 85 |
2015 |
Enhanced central memory cluster of differentiation 8+ and tumor antigen-specific T cells in prostate cancer patients receiving repeated in situ adenovirus-mediated suicide gene therapy. |
CM, GCV, IFN |
| 86 |
2015 |
Evidence for transcriptional interference in a dual-luciferase reporter system. |
3'UTR, CMV, EZH2, SV40 |
| 87 |
2015 |
Improving the safety of cell therapy with the TK-suicide gene. |
GVHD, GVT, HSCT |
| 88 |
2015 |
Liquid-based iterative recombineering method tolerant to counter-selection escapes. |
--- |
| 89 |
2015 |
Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo. |
CED, GCV, PBAE |
| 90 |
2015 |
Rapid and liquid-based selection of genetic switches using nucleoside kinase fused with aminoglycoside phosphotransferase. |
aph |
| 91 |
2015 |
Tumor Restrictive Suicide Gene Therapy for Glioma Controlled by the FOS Promoter. |
--- |
| 92 |
2014 |
2,3-Dihydroxy-quinoxaline induces ATPase activity of Herpes Simplex Virus thymidine kinase. |
--- |
| 93 |
2014 |
A fiber-modified adenovirus co-expressing HSV-TK and Coli.NTR enhances antitumor activities in breast cancer cells. |
Ad5, CAR, Coli.NTR |
| 94 |
2014 |
A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model. |
hTERT, IL |
| 95 |
2014 |
An autologous in situ tumor vaccination approach for hepatocellular carcinoma. 1. Flt3 ligand gene transfer increases antitumor effects of a radio-inducible suicide gene therapy in an ectopic tumor model. |
Adeno-Flt3L, DC, HCC, PFU, RT |
| 96 |
2014 |
Brain pharmacokinetics of ganciclovir in rats with orthotopic BT4C glioma. |
ECF, GCV |
| 97 |
2014 |
Inhibitory effects of the ultrasound-targeted microbubble destruction-mediated herpes simplex virus-thymidine kinase/ganciclovir system on ovarian cancer in mice. |
GCV, MBs, OC, US, UTMD |
| 98 |
2014 |
Prognostic utility of gene therapy with herpes simplex virus thymidine kinase for patients with high-grade malignant gliomas: a systematic review and meta analysis. |
GBM, HGGs, HR, MST, OR, OS |
| 99 |
2014 |
Suicide HSVtk gene delivery by neurotensin-polyplex nanoparticles via the bloodstream and GCV Treatment specifically inhibit the growth of human MDA-MB-231 triple negative breast cancer tumors xenografted in athymic mice. |
GCV, GFP, NTS, NTSR1, TNBC |
| 100 |
2014 |
Targeted expression of suicide gene by tissue-specific promoter and microRNA regulation for cancer gene therapy. |
EGP2-TK, EpCAM, Rb |
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