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Abbreviation : IFN-alpha
Long Form : interferon-alpha
No. Year Title Co-occurring Abbreviation
2019 A Functional Variant in Ubiquitin Conjugating Enzyme E2 L3 Contributes to Hepatitis B Virus Infection and Maintains Covalently Closed Circular DNA Stability by Inducing Degradation of Apolipoprotein B mRNA Editing Enzyme Catalytic Subunit 3A. cccDNA, CHB, HBeAg, HBV, UBE2L3
2019 A Long Noncoding RNA Regulates Hepatitis C Virus Infection Through Interferon Alpha-Inducible Protein 6. gRNA, HCV, ISGs, JAK-STAT, JFH-1, lncRNAs, PHHs, qRT-PCR, RNA-Seq
2019 A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years. SSPE
2019 A longitudinal study assessing depression in hepatitis C: Does gender play a role in the new-onset depression during interferon-alpha treatment? HCV, MDD, SVR
2019 Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3. BCLAF1, HSV-1, ISGF3, ISRE, PRV
2019 Blocking autophagy flux promotes interferon-alpha-mediated apoptosis in head and neck squamous cell carcinoma. ATG5, HNSCC, STAT1
2019 C/EBPbeta is a critical mediator of IFN-alpha-induced exhaustion of chronic myeloid leukemia stem cells. CML
2019 Clinical and positron emission tomography responses to long-term high-dose interferon-alpha treatment among patients with Erdheim-Chester disease. CNS, ECD, FDG-PET, OS, PFS, SUV
2019 Cytokines in the Treatment of Cancer. CPIs, GM-CSF, HD IL-2
10  2019 Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects. IFNAR, IFNs, ISG, PBMCs
11  2019 ER intrabody-mediated inhibition of interferon alpha secretion by mouse macrophages and dendritic cells. ER, ISGs
12  2019 Fib-4 Predicts Early Hematological Adverse Events Induced by Interferon-Based Triple Therapy in Chronic Hepatitis C Virus Patients. FIB4, HCV, SVR
13  2019 HIV-1-Mediated Suppression of IFN-alpha Production Is Associated with Inhibition of IRF-7 Translocation and PI3K/akt Pathway in Plasmacytoid Dendritic Cells. IRF, pDCs
14  2019 Imbalance in the ratio of CpG and polyG contributes to impaired interferon-alpha expression. CpG, HBV
15  2019 Immunopathogenesis of Behcet's Disease. BD, TNF-alpha
16  2019 Induction of interleukin 6 impairs the anti-HBV efficiency of IFN-alpha in human hepatocytes through upregulation of SOCS3. HBV, IL-6, SOCS3
17  2019 Interferon (IFN)-inducible Absent in Melanoma 2 proteins in the negative regulation of the type I IFN response: Implications for lupus nephritis. IFN, LN, SLE
18  2019 Interferon Alpha 2a and 2b in Ophthalmology: A Review. ---
19  2019 Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma. HNSCC, IFNAR1, PDL1, STAT1
20  2019 Interferon-alpha salvage treatment is effective for patients with acute leukemia/myelodysplastic syndrome with unsatisfactory response to minimal residual disease-directed donor lymphocyte infusion after allogeneic hematopoietic stem cell transplantation. DLI, MRD
21  2019 Interferon-alpha versus interleukin-2 in Chinese patients with malignant melanoma: a randomized, controlled, trial. IL-2
22  2019 Interferon-alpha-Induced Changes in NODDI Predispose to the Development of Fatigue. NDI, NODDI, ODI
23  2019 Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-alpha Identifies Antiviral Proteins Enriched in Exosomes. ---
24  2019 Minimal residual disease-directed immunotherapy for high-risk myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation. allo-HSCT, chemo-DLI, MDS, MRD
25  2019 Molecular cloning and transcriptional regulation of Indian peafowl (Pavo cristatus) IFN-alpha gene. ISGs
26  2019 Monitoring Disease Activity in Systemic Lupus Erythematosus With Single-Molecule Array Digital Enzyme-Linked Immunosorbent Assay Quantification of Serum Interferon-alpha. ELISA, SLE, SLEDAI
27  2019 Neuromyelitis optica spectrum disorder occurred after interferon alpha therapy in malignant melanoma. NMOSD
28  2019 Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen. SLE, SNPs
29  2019 On-treatment changes of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein are associated with the regression of liver fibrosis in chronic hepatitis B patients on interferon alpha add-on therapy. AUROC, CHB, M2BP, M2BP, P-I-R
30  2019 PASylated interferon alpha efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice. HBV, ISG, mIFNalpha, PAS
31  2019 Persistent fatigue induced by interferon-alpha: a novel, inflammation-based, proxy model of chronic fatigue syndrome. CFS, HCV, IL, TW
32  2019 Receptor tyrosine kinase MerTK suppresses an allogenic type I IFN response to promote transplant tolerance. ---
33  2019 Rh-IFN-alpha attenuates neuroinflammation and improves neurological function by inhibiting NF-kappaB through JAK1-STAT1/TRAF3 pathway in an experimental GMH rat model. GMH, i.c.v, rh-IFN-alpha, siRNA, TRAF3
34  2019 Upregulation of PITX2 Promotes Letrozole Resistance Via Transcriptional Activation of IFITM1 Signaling in Breast Cancer Cells. BCa, IFITM1
35  2019 Yellow fever virus modulates cytokine mRNA expression and induces activation of caspase 3/7 in the human hepatocarcinoma cell line HepG2. IL, TGF, YFV
36  2019 [Association of baseline alanine aminotransferase levels with therapeutic effects of entecavir and interferon-alpha in patients with chronic hepatitis B]. CHB, ETV
37  2019 [Chronic myeloid leukemia harboring T315I and F317L mutations successfully treated with interferon-alpha and ponatinib]. CML, CP, DAS, PON
38  2018 Activation of innate immunity in primary human cells using a plant virus derived nanoparticle TLR7/8 agonist. CP, PapMV, PBMC, pDCs, ssRNA, VLNP
39  2018 Alcohol attenuates anti-HCV function of IFN-lamda1 through up-regulation of PLASy expression in human hepatic cells. HCV, ISG56, Mx1, P-STAT1
40  2018 Analysis of MLN4924 (pevonedistat) as a potential therapeutic agent in malignant melanoma. ---
41  2018 Antidepressant-like effects of 3-carboxamido seco-nalmefene (3CS-nalmefene), a novel opioid receptor modulator, in a rat IFN-alpha-induced depression model. 3CS-nalmefene, BDNF, FST, HPA, OET
42  2018 Associations between type I interferon and antiphospholipid antibody status differ between ancestral backgrounds. aPL, dsDNA, SLE
43  2018 Astrocytes, an active player in Aicardi-Goutieres syndrome. AGS, ALS, CNS
44  2018 Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers. MDMs
45  2018 Calcium Phosphate Particles as Pulmonary Delivery System for Interferon-alpha in Mice. AUC, CaP, i.t, MRT, PK, VSV
46  2018 CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-alpha. JDM
47  2018 Cellular FLIP long isoform (cFLIPL)-IKKalpha interactions inhibit IRF7 activation, representing a new cellular strategy to inhibit IFNalpha expression. cFLIP, cFLIPL, cFLIPL
48  2018 Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-alpha as an effective therapeutic vaccine adjuvant. CHB, GM-CSF
49  2018 Clinical response to isotretinoin and interferon-alpha of two dogs with cutaneous epitheliotropic T-cell lymphoma: a case report. CETL
50  2018 Comprehensive evaluation of the host responses to infection with differentially virulent classical swine fever virus strains in pigs. CSFV, IL-2, TNF-alpha
51  2018 Current and future directions for the management of hepatitis B. cccDNA, HCC
52  2018 Cytokine profiling in active and quiescent SLE reveals distinct patient subpopulations. BLyS, PCA, SLE
53  2018 Defective Dendritic Cell Cytotoxic Activity of High-Grade Glioma Patients' Results from the Low Expression of Membrane TNFalpha and Can Be Corrected In Vitro by Treatment with Recombinant IL-2 or Exogenic Double-Stranded DNA. DCs, sTNFalpha, tmTNFalpha, TNF-alpha
54  2018 Deficits in temporal order memory induced by interferon-alpha (IFN-alpha) treatment are rescued by aerobic exercise. PFC, PRh
55  2018 Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity. Ab4DeltaORF2, EHV-1, Ig, PBMC
56  2018 Dihydropyrimidine dehydrogenase predicts survival and response to interferon-alpha in hepatocellular carcinoma. DPYD, EMT, HCC, TNM
57  2018 Distinct Regulation of CXCL10 Production by Cytokines in Human Salivary Gland Ductal and Acinar Cells. IFN-gamma, IL, pSS, TNF
58  2018 Effect of central injection of tumor-necrosis factor-like cytokine 1A and interferons on food intake in chicks. i.c.v, i.p, IFN-gamma, IFNs, LPS, TL1A, TNF
59  2018 Effects of preemptive interferon-alpha monotherapy in acute leukemia patients with relapse tendency after allogeneic hematopoietic stem cell transplantation: a case-control study. allo-HSCT, GVHD
60  2018 Evaluation of modified Interferon alpha mRNA constructs for the treatment of non-melanoma skin cancer. IVT, mRNA
61  2018 Excessive interferon-alpha signaling in autoimmunity alters glycosphingolipid processing in B cells. alpha-Gal A, GCS, GSLs
62  2018 Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization. FF, RI, VEGF
63  2018 Genetic variation in IL28B (IFNL3) and response to interferon-alpha treatment in myeloproliferative neoplasms. CR, MPN, PV
64  2018 Hepatitis B virus sensitivity to interferon-alpha in hepatocytes is more associated with cellular interferon response than with viral genotype. dHepaRG, HBV, PHH
65  2018 IFNalpha Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion. DCs, SLE, STING
66  2018 IgE in lupus pathogenesis: Friends or foes? IgE, pDCs, SLE
67  2018 Increased infiltration of CD11 c+/CD123+ dendritic cell subsets and upregulation of TLR/IFN-alpha signaling participate in pathogenesis of oral lichen planus. DC, FCM, OLP, TLRs
68  2018 Inhibition of TPL2 by interferon-alpha suppresses bladder cancer through activation of PDE4D. COX-2, PDE4D, PGE2, Tpl2
69  2018 Interferon alpha as antiviral therapy in chronic active Epstein-Barr virus disease with interstitial pneumonia - case report. allo-HSCT, CT, EBV, IP
70  2018 Interferon alpha gene expression and serum level association with low vitamin D levels in Egyptian female patients with systemic lupus erythematosus. ELISA, PCR, SLE, SLEDAI
71  2018 Interferon-alpha Combined With Herbal Compound "Songyou Yin" Effectively Inhibits the Increased Invasiveness and Metastasis by Insufficient Radiofrequency Ablation of Hepatocellular Carcinoma in an Animal Model. EMT, HCC, RFA, SYY
72  2018 Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma. EGFR, HNSCC, RIG-I, STAT1
73  2018 Interferon-alpha induces negative biases in emotional processing in patients with hepatitis C virus infection: a preliminary study. ---
74  2018 Interferon-alpha Is Effective for Treatment of Minimal Residual Disease in Patients with t(8;21) Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation: Results of a Prospective Registry Study. allo-HSCT, AML, MRD
75  2018 Interferon-alpha Subtypes As an Adjunct Therapeutic Approach for Human Immunodeficiency Virus Functional Cure. HAART, HIV
76  2018 Interferon-alpha Triggers Autoimmune Thyroid Diseases via Lysosomal-Dependent Degradation of Thyroglobulin. AITDs, LC3, Tg
77  2018 Interferon-alpha Up-Regulates the Expression of PD-L1 Molecules on Immune Cells Through STAT3 and p38 Signaling. DC
78  2018 Interferon-alpha-Mediated Activation of T Cells from Healthy and HIV-Infected Individuals Is Suppressed by Delta9-Tetrahydrocannabinol. HIV, IL-7, IL-7Ralpha, THC
79  2018 Long noncoding RNA PVT1 inhibits interferon-alpha mediated therapy for hepatocellular carcinoma cells by interacting with signal transducer and activator of transcription 1. HCC, LncRNA, STAT1
80  2018 Measuring type I interferon using reporter gene assays based on readily available cell lines. ELISAs, IFN, MOI, RGAs, SEAP
81  2018 miR-370 regulates ISG15 expression and influences IFN-alpha sensitivity in hepatocellular carcinoma cells. HCC
82  2018 Neutralizing Anti-Cytokine Autoantibodies Against Interferon-alpha in Immunodysregulation Polyendocrinopathy Enteropathy X-Linked. ACAAs, IPEX, Treg
83  2018 Nutlin sensitizes lung carcinoma cells to interferon-alpha treatment in MDM2-dependent but p53-independent manner. ---
84  2018 Pegylated Interferon-alpha-Induced Natural Killer Cell Activation Is Associated With Human Immunodeficiency Virus-1 DNA Decline in Antiretroviral Therapy-Treated HIV-1/Hepatitis C Virus-Coinfected Patients. HIV-1, NK
85  2018 Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8. pDC, SSc, TLR
86  2018 Porcine Mx1 Protein Inhibits Classical Swine Fever Virus Replication by Targeting Nonstructural Protein NS5B. BiFC, CSFV, GST, huMxA, IFN, poMx1, poMx2, RdRp, siRNA
87  2018 Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques. HIV, i.v, RMs, SIV
88  2018 Regulation of transforming growth factor is involved in the efficacy of combined 5-fluorouracil and interferon alpha-2b therapy of advanced hepatocellular carcinoma. 5-FU, ERK, TGF-beta
89  2018 Resveratrol Promoted Interferon-alpha-Induced Growth Inhibition and Apoptosis of SMMC7721 Cells by Activating the SIRT/STAT1. HCC, STAT1
90  2018 Reversing interferon-alpha neurotoxicity in a HIV-associated neurocognitive disorder mouse model. cART, HAND, ORT
91  2018 Safety, efficacy and pharmacodynamics of vesatolimod (GS-9620) in virally suppressed patients with chronic hepatitis B. AE, CHB, HBeAg, HBsAg, HBV, ISG, PBO
92  2018 Semisynthesis and biological evaluation of a cotylenin A mimic derived from fusicoccin A. CN-A, PPIs
93  2018 Subgroups of Sjogren's syndrome patients categorised by serological profiles: clinical and immunological characteristics. IL, SS, TSLP
94  2018 Targeting mitochondria by anthelmintic drug atovaquone sensitizes renal cell carcinoma to chemotherapy and immunotherapy. 5-FU, RCC
95  2018 The effects of vasoactive intestinal peptide in the rat model of experimental autoimmune neuritis and the implications for treatment of acute inflammatory demyelinating polyradiculoneuropathy or Guillain-Barre syndrome. EAN, FOXP3, VIP
96  2018 The IRF5 rs2004640 (G/T) polymorphism is not a genetic risk factor for systemic lupus erythematosus in population from south India. IRF5, SLE
97  2018 The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor. RBV, ZIKV
98  2018 Therapeutic Effect of Duck Interferon-Alpha Against H5N1 Highly Pathogenic Avian Influenza Virus Infection in Peking Ducks. AIV, rDuIFN-alpha, VSV
99  2018 Transport and delivery of interferon-alpha through epithelial tight junctions via pH-responsive poly(methacrylic acid-grafted-ethylene glycol) nanoparticles. GI
100  2018 Type I Interferon Potentiates IgA Immunity to Respiratory Syncytial Virus Infection During Infancy. NALT, RSV