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Abbreviation : IL-12
Long Form : interleukin-12
No. Year Title Co-occurring Abbreviation
2022 A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses. DC, IFN-gamma, IL-2
2022 A Single Nucleotide Polymorphism in SH2B3/LNK Promotes Hypertension Development and Renal Damage. Ang II, Arg, BP, IFNG, SH2B3, Trp
2022 A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors. TILs
2022 A2A Receptor Contributes to Tumor Progression in P2X7 Null Mice. A2AR, IFN-gamma, IL-17, IL-1beta, IL-6, P2X7R, TGF-beta, TNF-alpha, VEGF
2022 Activation-induced pyroptosis contributes to the loss of MAIT cells in chronic HIV-1 infected patients. cART, HIV-1, MAIT
2022 Antileishmanial activity, cytotoxicity and cellular response of amphotericin B in combination with crotamine derived from Crotalus durissus terrificus venom using in vitro and in silico approaches. AmB, CTA, ELISA, LDH, NO, TNF-alpha
2022 Assessment of IL-12, mRNA expression, vitamin-D level, and their correlation among the Mycobacterium tuberculosis cases. TB, TB, Th1
2022 Association of Inflammatory Cytokines With Non-Alcoholic Fatty Liver Disease. CIs, CRP, HRs, ICAM-1, IFN-gamma, IGF-II, IL-10, IL-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, MCP-1, NAFLD, NASH, ORs, TGF-beta, TNF-alpha
2022 Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway. AR, ARCR, ARCR, AS, CR, IFN-gamma, MMP-9
10  2022 Bifidobacterium animalis KV9 and Lactobacillus vaginalis FN3 alleviated β-lactoglobulin-induced allergy by modulating dendritic cells in mice. beta-LG, beta-LG-sIgE, DCs, IL-4, TLR4
11  2022 Biogenesis and engineering of interleukin 12 family cytokines. ---
12  2022 Borrelia burgdorferi Is a Poor Inducer of Gamma Interferon: Amplification Induced by Interleukin-12. IFN-gamma, LB, PBMCs
13  2022 Cancer immunotherapy using artificial adjuvant vector cells to deliver NY-ESO-1 antigen to dendritic cells in situ. DCs, iNKT, NK
14  2022 Captopril Combined with Furosemide or Hydrochlorothiazide Affects Macrophage Functions in Mouse Contact Hypersensitivity Response. NO, ROIs
15  2022 Cell membrane-anchored and tumor-targeted IL-12 (attIL12)-T cell therapy for eliminating large and heterogeneous solid tumors. aIL-12, attIL12, TCR-T, ttIL12
16  2022 Cell surface-tethered IL-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy. ---
17  2022 Changes in Histological Structure, Interleukin 12, Smooth Muscle Actin and Nitric Oxide Synthase 1. and 3. Expression in the Liver of Running and Non-Running Wistar Rats Supplemented with Bee Pollen or Whey Protein. alpha-SMA, eNOS
18  2022 Characterization of disulfide bridges pattern of recombinant human interleukin 12 fusion protein p40 subunit and identification and quantification of cysteinylated free cysteine 252. MS
19  2022 Combination of thermal ablation by focused ultrasound, pFAR4-IL-12 transfection and lipidic adjuvant provide a distal immune response. HIFU, IFN-gamma, pFAR4, TLR2, TNF-alpha
20  2022 CSF TNF and osteopontin levels correlate with the response to dimethyl fumarate in early multiple sclerosis. CLs, CSF, DMF, DMTs, IFN, MRI, MS, OR, RRMS, TNF, WM
21  2022 Cytotoxic T Lymphocyte Activation Signals Modulate Cytoskeletal Dynamics and Mechanical Force Generation. APCs, CTLs, IS, TIRF
22  2022 Diagnostic and Prognostic Biomarkers of Coronavirus Disease 2019 in Children. COVID-19, IL-1beta, IP-10
23  2022 Disrupting Interleukin 12 Improves Microvascular Endothelial Function in Type 2 Diabetes Through ER Stress CHOP and Oxidative Stress Mechanisms. ER, GTT
24  2022 Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation. IFNbeta, LPS, SARS-CoV-2
25  2022 Effect of Qingfei Huaxian Decoction combined with prednisone acetate on serum inflammatory factors and pulmonary function of patients with idiopathic pulmonary fibrosis. FEV1, FVC, HA, IL-18, IL-6, IPF, LN
26  2022 Effects of Astragalus Polysaccharides on CD8+ Tissue-Resident Memory T Cells in Mice with Herpes Simplex. APS, GO, IFN-gamma, KEGG
27  2022 Elevated Retinol Binding Protein 3 Concentrations Are Associated With Decreased Vitreous Inflammatory Cytokines, VEGF, and Progression of Diabetic Retinopathy. DR, PDR, RBP3, TNF-alpha, VEGF
28  2022 Engineered Mesenchymal Stem Cells as a Biotherapy Platform for Targeted Photodynamic Immunotherapy of Breast Cancer. MB, pIL12
29  2022 Evaluation of an ImmunoPET Tracer for IL-12 in a Preclinical Model of Inflammatory Immune Responses. LPS, PET
30  2022 Functional insights into Brucella transcriptional regulator ArsR. IFN-gamma, IL-18, TNF-alpha
31  2022 Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells. ASOs, NF-kappaB, NSCs, STAT3
32  2022 Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia. AML, HCT, ML, NK, RIC
33  2022 Identification and functional characterization of interleukin-12 receptor beta 1 and 2 in grass carp (Ctenopharyngodon idella). gcIl-12rbeta1, IL-12Rbeta1, rgcIl-12
34  2022 IL12 immune therapy clinical trial review: Novel strategies for avoiding CRS-associated cytokines. attIL12-T
35  2022 Immunostimulatory effects of Nannochloropsis oculata supplementation on Barki rams growth performance, antioxidant assay, and immunological status. gamma-IF, IL-6, LTT, MDA, TAC, TNF-alpha
36  2022 Interleukin-12 as an in situ cancer vaccine component: a review. ---
37  2022 Interleukin-12 Plasmid DNA Delivery by N-[(2-Hydroxy-3-trimethylammonium)propyl]chitosan-Based Nanoparticles. CS, HTCS
38  2022 Interplay between plasmacytoid dendritic cells and tumor-specific T cells in peripheral blood influences long-term survival in non-small cell lung carcinoma. OS, pDCs
39  2022 Intranasal Delivery of Thermostable Subunit Vaccine for Cross-Reactive Mucosal and Systemic Antibody Responses Against SARS-CoV-2. ACE2, CS, RBD
40  2022 Listeria Meningitis in a Patient With Plaque Psoriasis on Ustekinumab Therapy. IL-23
41  2022 Localized Nano-mediated Interleukin-12 Gene Therapy: Promising Candidate for Cancer Immunotherapeutics. ---
42  2022 Loss of YTHDF1 in gastric tumors restores sensitivity to antitumor immunity by recruiting mature dendritic cells. DCs, GC, IFN-gamma
43  2022 Maintenance and gene electrotransfer efficiency of antibiotic resistance gene-free plasmids encoding mouse, canine and human interleukin-12 orthologues. ---
44  2022 Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker. ---
45  2022 Metformin modulate immune fitness in hepatocellular carcinoma: Molecular and cellular approach. CTLA-4, FoxP3, HCC, IFN-gamma, MDSCs, PD-1, TGF-beta
46  2022 Metronidazole, acyclovir and tetrahydrobiopterin may be promising to treat COVID-19 patients, through interaction with interleukin-12. ACV, MTZ, THB
47  2022 Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways. ATP, IFN, IL23, JAK, JH1, JH2, TYK2
48  2022 Oral administration of Lactiplantibacillus plantarum NR16 isolated from Kimchi ameliorates murine allergic rhinitis. AR, IFN-gamma, Th2
49  2022 Phytochemical Analysis and Immunomodulatory Potential on Diabetic-Infected Tuberculosis by Fruit Etlingera rubroloba A.D. Poulsen. DM
50  2022 Pilot Study on the Impact of a Home-Based Exercise Program on Inflammatory Cytokines and Quality of Life in Men with Prostate Cancer Under Active Surveillance. 6MWT, IL-1alpha, IL-5, IL-6, INF-gamma, TNF-alpha, VEGF
51  2022 Preclinical and clinical studies of bintrafusp alfa, a novel bifunctional anti-PD-L1/TGFβRII agent: Current status. FDA, HPV, ORR, TME
52  2022 Refractory Mycobacterium genavense infection secondary to thymoma-associated endogenous IL-12 inhibitor. IFN-gamma, MG
53  2022 Removal of the Erns RNase Activity and of the 3' Untranslated Region Polyuridine Insertion in a Low-Virulence Classical Swine Fever Virus Triggers a Cytokine Storm and Lethal Disease. CSF, CSFV, PdR, UTR
54  2022 Structural Insights from Molecular Modeling of Isoindolin-1-One Derivatives as PI3Kγ Inhibitors against Gastric Carcinoma. CoMFA, CoMSIA, GC, GPCRs, MD, PI3Kgamma, SAR, TAM, TNF-alpha
55  2022 Systemically targeted cancer immunotherapy and gene delivery using transmorphic particles. TNF-alpha, TPA
56  2022 Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models. GBM, IFN-alpha, TME
57  2022 The Diagnostic Value of Combined Detection of Serum Lp-PLA2 and Hcy and Color Doppler in Elderly Patients with Acute Coronary Syndrome and Effect on Endothelial Function. ACS, AST, Hcy, IL-13, IL-2, Lp-PLA2, ROC
58  2022 The Role of Vitamin D for Modulating the T Helper 1 Immune Response After the Coronavac Vaccination. COVID-19, IFN-gamma, SARS-CoV-2, Th1
59  2022 Therapeutic efficacies of two newly isolated Edwardsiella phages against Edwardsiella piscicida infection. IL-1beta, IL-6, MDR, TNF-alpha
60  2022 TNF blockade enhances the efficacy of myxoma virus-based oncolytic virotherapy. OV, TNF
61  2022 Toxoplasma gondii infection possibly reverses host immunosuppression to restrain tumor growth. DCs, GRAs, IFN-gamma, ROPs
62  2022 Transdermal delivery of interleukin-12 gene targeting dendritic cells enhances the anti-tumour effect of programmed cell death protein 1 monoclonal antibody. DCs, MC, TCI
63  2022 Treatment of skin tumors with intratumoral interleukin 12 gene electrotransfer in the head and neck region: a first-in-human clinical trial protocol. GET
64  2022 TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation. OPTN, TRIM14
65  2021 2-Amino-3-methylimidazo[4,5-f]quinoline induced oxidative stress and inflammation via TLR4/MAPK and TLR4/NF-κB signaling pathway in zebrafish (Danio rerio) livers. AST, CAT, GSH-Px, GST, IL-1beta, IL-6, MDA, ROS, SOD, TNF-alpha
66  2021 A Novel Combined DNA Vaccine Encoding Toxoplasma gondii SAG1 and ROP18 Provokes Protective Immunity Against a Lethal Challenge in Mice. INF-gamma, ROP18, SAG1, T. gondii
67  2021 A uracil auxotroph Toxoplasma gondii exerting immunomodulation to inhibit breast cancer growth and metastasis. RH-Deltaompdc, TME, TNBC
68  2021 Activating a collaborative innate-adaptive immune response to control metastasis. IFN, iNOS, MPLA, TAMs, TNF-alpha
69  2021 Active Hexose-Correlated Compound Restores Gene Expression and Protein Secretion of Protective Cytokines of Immune Cells in a Murine Stress Model during Chlamydia muridarum Genital Infection. AHCC, BMDCs, IFN-gamma
70  2021 Ambroxol Treatment Suppresses the Proliferation of Chlamydia pneumoniae in Murine Lungs. Ax, IFN-gamma, IFUs, SP
71  2021 Anti-HBV Activities of Polysaccharides from Thais clavigera (Kuster) by In Vitro and In Vivo Study. HBV, HBV-Tg, IFN-gamma, IL-4, TAF
72  2021 Association Between Interleukin-12 and Sarcopenia. GEO, OR, TGF-beta
73  2021 Association of interleukin-12B rs6887695 with susceptibility to allergic rhinitis. AR, PCR-RFLP, SNPs
74  2021 Benzo[a]pyrene immunogenetics and immune archetype reprogramming of lung. BaP, CTLA-4, FoxP3, IFN-gamma, MDSCs, PD-1, TGF-beta
75  2021 Calcium sensing receptor hyperactivation through viral envelop protein E of SARS CoV2: A novel target for cardio-renal damage in COVID-19 infection. CaSR, CoVs, IFNgamma
76  2021 Coinfection of porcine deltacoronavirus and porcine epidemic diarrhea virus increases disease severity, cell trophism and earlier upregulation of IFN-alpha and IL12. IFN-alpha, PDCoV, PEDV, VH
77  2021 Combined immunotherapy with controlled interleukin-12 gene therapy and immune checkpoint blockade in recurrent glioblastoma: An open-label, multi-institutional phase I trial. mOS, rGBM, VDX
78  2021 Contribution of Interleukin-12A Genotypes to Breast Cancer Risk. ---
79  2021 Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer: A meta-analysis. CA, CEA, CIK, DC-CIK, EC, IL-2, RCTs, TNF-alpha
80  2021 Diospyros Peregrina Fruit Preparation Mediated Immunomodulation of Lymphocytes Isolated From The Blood of Breast Cancer Patients. BRCA1, DFP, IFNG, IL-4, NO, STAT1, TBX21, Th
81  2021 Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant. AML, DLIs, HCT, ML, NK, YA
82  2021 Effects of Yupingfeng nasal drops on serum cytokines, histopathology and eosinophil cationic protein in nasal mucosa of rats with allergic rhinitis. AR, ECP, IL-4, INF-gamma, OVA, SD, Th1, Th2, YPF
83  2021 Electroacupuncture interventions alleviates myocardial ischemia reperfusion injury through regulating gut microbiota in rats. EA, ELISA, HE, IL-6, LPS, MIRI, TLR4
84  2021 Enhancement of doxorubicin anti-cancer activity by vascular targeting using IsoDGR/cytokine-coated nanogold. TNF
85  2021 Evaluation of the efficiency of modified PAMAM dendrimer with low molecular weight protamine peptide to deliver IL-12 plasmid into stem cells as cancer therapy vehicles. MSCs, PAMAM
86  2021 FTZ Ameliorates Diabetic Cardiomyopathy by Inhibiting Inflammation and Cardiac Fibrosis in the Streptozotocin-Induced Model. Ccr2, CON, DCM, FTZ
87  2021 Gemini Cationic Lipid-Type Nanovectors Suitable for the Transfection of Therapeutic Plasmid DNA Encoding for Pro-Inflammatory Cytokine Interleukin-12. GCLs
88  2021 Helicobacter-stimulated IL-10-producing B cells suppress differentiation of lipopolysaccharide/Helicobacter felis-activated stimulatory dendritic cells. BMDCs, DCs, H. felis, IL-10, IL-6, LPS, TNF-alpha
89  2021 Human IL-15 Inhibits NK Cells Specific for Human NK-92 Cells. NK, PBMCs
90  2021 Identification and Characterization of Rift Valley Fever Virus-Specific T Cells Reveals a Dependence on CD40/CD40L Interactions for Prevention of Encephalitis. MHC-II, RVFV
91  2021 IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation. IF, KO, scRNA-seq
92  2021 Immunogenicity of Whole Mycobacterium intracellulare Proteins and Fingding on the Cross-Reactive Proteins between M. intracellulare and M. tuberculosis. IFN-gamma, IL-2, IL-6
93  2021 Immunology of IL-12: An update on functional activities and implications for disease. IFN-gamma, IL-12R, NK, STAT4, Th1
94  2021 Immunomodulatory effects of Andrographis paniculata extract in healthy adults - An open-label study. IFN-gamma, IL-2, IL-4, SAPE, TNF-alpha
95  2021 Integrating disulfides into a polyethylenimine gene carrier selectively boosts significant transfection activity in lung tissue enabling robust IL-12 gene therapy against metastatic lung cancers. ---
96  2021 Interleukin 12p40 Deficiency Promotes Abdominal Aortic Aneurysm by Activating CCN2/MMP2 Pathways. AAA, ALK-1, CCN2, Cd-40L, DKO, IL-12p40, Il17e
97  2021 Intratumoral expression of IL-12 from lentiviral or RNA vectors acts synergistically with TLR4 agonist (GLA) to generate anti-tumor immunological memory. GLA-SE
98  2021 Linarin Protects the Kidney against Ischemia/Reperfusion Injury via the Inhibition of Bioactive ETS2/IL-12. AKI, IRI, LIN, PPI, siRNA
99  2021 Lipopolysaccharide-induced inflammation in human peritoneal mesothelial cells is controlled by ERK1/2-CDK5-PPARγ axis. CDK, Cdk5, ELISA, IL-1beta, IL-6, LPS, PPAR
100  2021 Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma. ---