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Abbreviation : IL-1
Long Form : interleukin-1 alpha
No. Year Title Co-occurring Abbreviation
2014 Integrin alpha1beta1 differentially regulates cytokine-mediated responses in chondrocytes. TGF-beta1
2009 Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. sGAG
2009 Effects of chloroquine treatment on circulating erythropoietin and inflammatory cytokines in acute Plasmodium falciparum malaria. EPO, INF-gamma, TNF-alpha
2008 Radioprotection of murine gastrointestinal epithelium by interleukin-1alpha involves down-regulation of the apoptotic response. AI, XRT
2006 The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin. HUVEC, PCR
2005 Effects of glucosamine hydrochloride and chondroitin sulphate, alone and in combination, on normal and interleukin-1 conditioned equine articular cartilage explant metabolism. CS, GAG, GU
2005 Serial changes in plasma levels of cytokines in patients with coronary artery disease. ACS, CAD, CRP, IFN, IL-10, IL-6, SA, TNF
2005 Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels. MMP-9, SMC, SV
2004 Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts. 5-ASA, COX
10  2003 Chronic repetitive reaching and grasping results in decreased motor performance and widespread tissue responses in a rat model of MSD. UE
11  2003 Effects of dosage titration of methylprednisolone acetate and triamcinolone acetonide on interleukin-1-conditioned equine articular cartilage explants in vitro. GAG, MPA, TA
12  2003 Non-functional Fas ligand increases the formation of cartilage early in the endochondral bone induction by rhBMP-2. BMP, rh, TNF-alpha
13  2003 Serum cytokine level and production of reactive oxygen species (ROS) by blood neutrophils from a schizophrenic patient with hypersensitivity to neuroleptics. DIC, NMS, ROS, TNF-alpha
14  2003 Substance induced plasticity in noradrenergic innervation of the paraventricular hypothalamic nucleus. CRH, HPA, PVN
15  2002 Decreased tumor blood flow as measured by positron emission tomography in cancer patients treated with interleukin-1 and carboplatin on a phase I trial. PET, PMN
16  2000 Alveolar type II cell abnormalities and peroxide formation in lungs of rats given IL-1 intratracheally. ALI, ATII, BAL, GGT
17  2000 Regional variations in the transport of interleukin-1alpha across the blood-brain barrier in ICR and aging SAMP8 mice. BBB, transport rate
18  2000 Retinoic acid combines with interleukin-1 to promote the degradation of collagen from bovine nasal cartilage: matrix metalloproteinases-1 and -13 are involved in cartilage collagen breakdown. RetA, TIMP
19  1999 In vitro differences between astrocytes of control and wobbler mice spinal cord. ALS, CORT, GFAP, TGF-beta1
20  1999 Inhibition of fibronectin-activated migration of microvascular endothelial cells by interleukin-1alpha, tumour necrosis factor alpha and interferon gamma. EC, FGF, HGF, IFN, TNF, VEGF
21  1999 Troglitazone upregulates nitric oxide synthesis in vascular smooth muscle cells. IFN, NO, PPARgamma, VSMC
22  1998 Cytokine kinetics and other host factors in response to pneumococcal pulmonary infection in mice. BAL, IL-6, LTB4, NO, TNF
23  1998 Ex vivo cytokine expansion of peripheral blood Ph-negative cells in chronic myeloid leukaemia. 5-FU, CML, FLT3L, IL-3, LIF, PB, Ph, SCF, TPO
24  1998 In vitro expression of MMP-2 and MMP-9 in glioma cells following exposure to inflammatory mediators. PMA, TNF-alpha
25  1998 Interleukin 1 alpha (IL-1) and macrophage colony-stimulating factor (M-CSF) accelerate recovery from multiple drug-induced myelosuppression. AdR, M-CSF, MTD
26  1998 Nitric oxide suppresses bFGF- and IL-1-alpha-mediated but not VEGF165-mediated angiogenesis in natively vascularized mammalian tissue. bFGF
27  1998 Selective induction of cell-associated interleukin-1alpha in murine keratinocytes by chemical allergens. ---
28  1997 Antioxidant enzyme activity in murine hematopoietic bone marrow following treatment with interleukin 1 alpha: influence of tumor. LLCa
29  1997 Pyrrolidine dithiocarbamate inhibits cytokine-induced VCAM-1 gene expression in rat cardiac myocytes. IFN, NF-kappaB, VCAM-1
30  1997 Secondary cytokines interact in sequence with interleukin-1alpha (IL-1alpha) with or without macrophage colony-stimulating factor (M-CSF) to further accelerate granulopoietic recovery in myelosuppressed animals. 5-FU, IL-1alpha, M-CSF
31  1997 Subgingival temperature: relation to gingival crevicular fluid enzymes, cytokines, and subgingival plaque micro-organisms. BG, GCF, IFN, MPO, NE, PI
32  1996 A sustained reduction in IkappaB-beta may contribute to persistent NF-kappaB activation in human endothelial cells. EC, PMA, TNF
33  1996 Context-dependent behavioral effects of interleukin-1 in the rhesus monkey (Macaca mulatta). ---
34  1996 Different behaviour of radioiodinated human recombinant interleukin-1 and its receptor antagonist in an animal model of infection. IL-1ra
35  1996 IL-1alpha gene-transfected human melanoma cells increase tumor-cell adhesion to endothelial cells and their retention in the lung of nude mice. CM, EC
36  1996 Interleukin-1 stimulates rapid release of cytokine-induced neutrophil chemoattractant (CINC) in rat lungs. AM, CINC, MPO
37  1996 Synthesis of interleukin-1, interleukin-6, and basic fibroblast growth factor by human cataract lens epithelial cells. bFGF, EGF, LECs, TNF-alpha
38  1996 Tumor necrosis factor induced acute lung leak in rats: less than with interleukin-1. ARDS, CINC, MPO, TNF
39  1996 Tumor necrosis factor-alpha suppresses the regrowth of fractionated irradiated endothelial cells in vitro. ECs, FAA, HUVEC, INF, TNF
40  1995 Bafilomycin A1 inhibits IL-1-stimulated proteoglycan degradation by chondrocytes without affecting stromelysin synthesis. ---
41  1995 Differential effects of interleukin-1 alpha, tumor necrosis factor-alpha, indomethacin, hydrocortisone, and macrophage co-culture on the proliferation of human fibroblasts and peritoneal mesothelial cells. PMC, TNF
42  1995 Lipopolysaccharide (LPS) increases the in vivo oxidation of branched-chain amino acids in the rat: a cytokine-mediated effect. LPS, TNF
43  1995 Permeability of the blood-brain barrier to soluble cytokine receptors. BBB, muIL-1R, TNF
44  1995 Rat fibroblasts synthesize T-kininogen in response to cyclic-AMP, prostaglandin E2 and cytokines. ---
45  1994 Blood-borne interleukin-1 alpha is transported across the endothelial blood-spinal cord barrier of mice. BBB, CNS, HPLC, I-IL
46  1994 Cellular distribution of pulmonary Mn and CuZn superoxide dismutase: effect of hyperoxia and interleukin-1. SOD
47  1994 CGP 47969A: a novel inhibitor of the synthesis of inflammatory cytokines. LPS, TNF
48  1994 Combined activity of interleukin-1 alpha or TNF-alpha and doxorubicin on multidrug resistant cell lines: evidence that TNF and DXR have synergistic antitumor and differentiation-inducing effects. DXR, MDR, TNF
49  1994 Cytokine-induced expression of nitric oxide synthase in C2C12 skeletal muscle myocytes. IFN, iNOS, LPS, NO, NOS, RT-PCR, TNF
50  1994 Developmental expression of cytokine genes in the cortex and hippocampus of the rat central nervous system. CNS, IL-2, IL-6, M-CSF, MCP-1, RT-PCR
51  1994 Induction of cyclooxygenase II in human synovial microvessel endothelial cells by interleukin-1. Inhibition by glucocorticoids. COX, HSE, mRNA
52  1994 Interleukin 1 and tumor necrosis factor production as the initial stimulants of liver ischemia and reperfusion injury. PMNs, TNF
53  1994 Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21ras, Raf-1, and MAP kinase kinase. MAP, MBP
54  1994 Interleukin-1-induced lung neutrophil accumulation and oxygen metabolite-mediated lung leak in rats. DMSO
55  1994 Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1. 8-BrcAMP, PGE2, PKA, PKC, TPA
56  1994 Signal transduction pathway(s) involved in phorbol ester and autocrine induction of interleukin-1 alpha mRNA in murine keratinocytes. PKC, TPA
57  1993 An oligomer targeted against protein kinase C alpha prevents interleukin-1 alpha induction of cyclooxygenase expression in human endothelial cells. COX, PKC
58  1993 Cytokine activation of human macro- and microvessel-derived endothelial cells. ECM, HSE, HUVE, uPA
59  1993 Cytokine modulation of endothelial cell sensitivity to photodynamic therapy. FGF, PDGF, PDT, TGF, TNF
60  1993 Cytokines increase neutral endopeptidase activity in lung fibroblasts. cAMP, NEP, TNF-alpha
61  1993 Interleukin-1 alpha and interleukin-6 act additively to inhibit growth of MCF-7 breast cancer cells in vitro. IL-6, PR, TGF-beta
62  1993 Postinsult treatment with N-acetyl-L-cysteine decreases IL-1-induced neutrophil influx and lung leak in rats. NAC
63  1993 Potentiation of in vivo antitumor effects of recombinant interleukin-1 alpha by gelatin conjugation. i.p
64  1993 Quantitation of cytokine levels in skin graft donor site wound fluid. bFGF, EGF, EIA, ELISA, PDGF, TNF-alpha
65  1993 Release of cell surface proteoglycan from chondrocytes by interleukin-1. sGAG
66  1993 Relevance of tumour necrosis factor-alpha and interleukin-1-alpha in the pathogenesis of hypoxia-related organ failure. TNF
67  1993 Temporal and spatial immunolocalization of cytokines in murine chronic granulomatous tissue. Implications for their role in tissue development and repair processes. bFGF, EGF, PDGF, TGF-beta, TNF-alpha
68  1993 [The role of matrix metalloproteinases for premature rupture of the membranes]. MMPs, PGE2, PROM, TIMP, TNF-alpha
69  1992 Effects of anti-inflammatory drugs and agents that modify intracellular transduction signals or metabolic activities in inflammatory cells on interleukin-1 induced cartilage proteoglycan resorption in vitro. PrGn
70  1992 Effects of recombinant monokines on hepatic pyruvate dehydrogenase, pyruvate dehydrogenase kinase, lipogenesis de novo and plasma triacylglycerols. Abolition by prior fasting. PDHa, TG, TNF
71  1992 IL-6 enhances TNF-alpha- and IL-1-induced increase of Mn superoxide dismutase mRNA and O2 tolerance. IL-6, MnSOD, TNF-alpha
72  1992 Induction of HLA class I mRNA by cytokines in human fibroblasts: comparison of TNF, IL-1 and IFN-beta. IFN-beta, TNF
73  1992 Inhibition of interleukin-1-alpha-induced nitric oxide synthase in vascular smooth muscle and full reversal of interleukin-1-alpha-induced hypotension by N omega-amino-L-arginine. NAA, NMA, NNA, NO
74  1992 Interleukin-1-induced alterations in glomerular proteoglycans: biochemical and tissue autoradiographic aspects. GAG, HSPG
75  1992 Kinetics of pulmonary superoxide dismutase in interleukin-1-induced oxygen-tolerant rats. MnSOD
76  1992 N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage. ---
77  1992 Noradrenergic innervation of the hypothalamus participates in adrenocortical responses to interleukin-1. CS, HPA, NE, PVN
78  1992 Production of both 92- and 72-kDa gelatinases by bone cells. CM, PTH, TNF, TPA
79  1992 Synergistic antiproliferative effects of the combination of interleukin-1 alpha and doxorubicin against human melanoma cells. ---
80  1992 Synergy between recombinant human IL-1 alpha (rHuIL-1) and M-CSF (rHuM-CSF) during the recovery of murine hematopoietic activity in myelosuppressed animals: abbreviated versus chronic administration of rHuM-CSF. 5-FU, CFU-M, M-CSF, rHuIL-1
81  1992 Tumor necrosis factor alpha and interleukin 1 alpha enhance lipopolysaccharide-mediated bovine endothelial cell injury. AMs, EC, LPS, TNF
82  1992 Up-regulated biosynthesis and expression of endothelial cell vitronectin receptor enhances cancer cell adhesion. ---
83  1991 Cytokine administration alters the distribution of activated lymphocytes to the lung. Con A, IL-2, TNF
84  1991 Detectable serum levels of tumor necrosis factor alpha may predict early mortality in elderly institutionalized patients. TNF
85  1991 Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C. LPS, NF-kappaB, PMA
86  1991 Human recombinant interleukin-1 alpha protection against the lethality of endotoxin and experimental sepsis in mice. CLP, TNF
87  1991 Induction of hepatocyte mitosis in intact adult rat by interleukin-1 alpha and interleukin-6. IL-6, PH
88  1991 Influence of staurosporine, nitrendipine and monooleoylglycerol on interleukin-1-induced insulin secretion and phosphoinositide hydrolysis. PI
89  1991 Interleukin 1 alpha stimulates hemopoiesis but not tumor cell proliferation and protects mice from lethal total body irradiation. TBI
90  1991 Interleukin 1 protects rats against oxygen toxicity. Mn-SOD
91  1991 Interleukin-1 alpha and tumor necrosis factor-alpha (TNF alpha) inhibit growth and induce TNF messenger RNA in MCF-7 human breast cancer cells. TNF, TNF-alpha
92  1991 Leukoregulin, a novel cytokine enhances the anti-herpesvirus actions of acyclovir. HSV-1, IFN
93  1991 Marijuana components stimulate human peripheral blood mononuclear cell secretion of interferon-gamma and suppress interleukin-1 alpha in vitro. CBD, IFN, IL-2, PBMC, THC, TNF
94  1991 Mechanism of regulation of prostaglandin production by parathyroid hormone, interleukin-1, and cortisol in cultured mouse parietal bones. AA, PG, PTH
95  1991 Prediction of successful embryo implantation by measuring interleukin-1-alpha and immunosuppressive factor(s) in preimplantation embryo culture fluid. IVF
96  1991 Tumor necrosis factor-alpha and interleukin 1-alpha regulate transferrin receptor in human diploid fibroblasts. Relationship to the induction of ferritin heavy chain. ---
97  1990 Antitumor activity of recombinant human interleukin-1 against heterotransplanted human non-Hodgkin lymphomas in nude mice. ---
98  1990 Effect of plasma from cancer patients on rat skeletal muscle protein degradation and PGE2 release in vitro. ---
99  1990 Effects of androgens on parathyroid hormone and interleukin-1-stimulated prostaglandin production in cultured neonatal mouse calvariae. DHT, PGE2
100  1990 Granulocyte macrophage--colony-stimulating factor (GM-CSF) decreases CD1a expression by human Langerhans cells and increases proliferation in the mixed epidermal cell-lymphocyte reaction (MELR). GM-CSF, LC, MELR, TNF-alpha