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Abbreviation : IL-1
Long Form : interleukin-1beta
No. Year Title Co-occurring Abbreviation
2019 Corticosterone and progesterone differentially regulate HPA axis and neuroimmune responses to stress in male rats. CORT, PROG, PVN
2019 Imaging findings of sterile pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome: differential diagnosis and review of the literature. PAPA
2019 RelB acts as a molecular switch driving chronic inflammation in glioblastoma multiforme. GBM, OSM, SIRT1, YY1
2016 Sleep and immunomodulatory responses to systemic lipopolysaccharide in mice selectively expressing interleukin-1 receptor 1 on neurons or astrocytes. IL-1R1, LPS, NREMS, REMS
2015 Acute increases in intramuscular inflammatory cytokines are necessary for the development of mechanical hypersensitivity in a mouse model of musculoskeletal sensitization. NF-kappaB, TNF
2015 Alteration in peripheral blood concentration of certain pro-inflammatory cytokines in cows developing retention of fetal membranes. IL-6, IL-8, RFM, TNF-alpha
2015 Antipyretic and anti-inflammatory activities of Thais luteostoma extracts and underlying mechanisms. cAMP, IL-2, IL-6, PGE2, TLSH
2015 Selective contributions of neuronal and astroglial interleukin-1 receptor 1 to the regulation of sleep. CNS, EEG, IL-1R1, NREMS, REMS, WT
2014 Chromatin immunoprecipitation analysis of bortezomib-mediated inhibition of NFkappaB recruitment to IL-1beta and TNFalpha gene promoters in human macrophages. BZ, ChIP, TNF
10  2014 The inflamed axis: the interaction between stress, hormones, and the expression of inflammatory-related genes within key structures comprising the hypothalamic-pituitary-adrenal axis. HPA
11  2014 The role of oxidative stress and inflammatory response in high-fat diet induced peripheral neuropathy. GPx, HDL, IL-6, MDA, NO, PON1, SOD, TGF-beta, TNF-alpha
12  2013 Crosstalk between mesenchymal stem cells and endothelial cells leads to downregulation of cytokine-induced leukocyte recruitment. EC, MSC, TNF
13  2013 Interleukin-1beta and tumor necrosis factor-alpha: reliable targets for protective therapies in Parkinson's Disease? PD, SN, TNF
14  2012 Analysing the role of UVB-induced translational inhibition and PP2Ac deactivation in NF-kappaB signalling using a minimal mathematical model. NF-kappaB, UVB
15  2012 Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor gamma expression in human osteoarthritic chondrocytes. ChIP, CHX, OA, PPAR, RT-PCR, siRNA, Sp1
16  2012 Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2. LMP2
17  2012 Sterile inflammatory response in acute pancreatitis. DAMPs, TLR
18  2010 MMP-mediated collagen breakdown induced by activated protein C in equine cartilage is reduced by corticosteroids. APC, GAG, MMP, MPA, OA, TNF-alpha
19  2010 Neutrophil elastase activity and concentrations of interleukin 1-beta in crevicular fluid after immediate replacement and immediate loading of implants. ---
20  2010 Screening of five essential oils for identification of potential inhibitors of IL-1-induced Nf-kappaB activation and NO production in human chondrocytes: characterization of the inhibitory activity of alpha-pinene. NO
21  2009 Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress. ---
22  2008 Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes. BA, COX, EMSA, HDAC, iNOS, NF, NO, OA, RT-PCR, TNF-alpha, TSA
23  2008 Long-chain polyunsaturated fatty acids modulate interleukin-1beta-induced changes in behavior, monoaminergic neurotransmitters, and brain inflammation in rats. AA, DA, EPA, GLA, NA, PG
24  2008 Nitric oxide synthase isoforms and NF-kappaB activity in normal and osteoarthritic human chondrocytes: regulation by inducible nitric oxide. NO, OA
25  2008 Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteins. NO
26  2008 Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge. BBB, beta-ADRs, E. coli
27  2007 Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression. EORP
28  2007 Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120. i.t, IL-6, TNF
29  2006 Alkali-soluble polysaccharides of Rhizoclonium riparium alga induce IL-1 gene expression via protein kinase signaling pathways. ERK, JNK
30  2006 LTA and LPS mediated activation of protein kinases in the regulation of inflammatory cytokines expression in macrophages. LPS, LTA, TNF
31  2006 The comparison of changes in behavior, neurochemistry, endocrine, and immune functions after different routes, doses and durations of administrations of IL-1beta in rats. i.c.v, i.p
32  2005 Endogenous prostaglandin D(2) synthesis decreases vascular cell adhesion molecule-1 expression in human umbilical vein endothelial cells. HUVEC, VCAM
33  2005 Interleukin 1beta enhances non-rapid eye movement sleep and increases c-Fos protein expression in the median preoptic nucleus of the hypothalamus. IR, MnPN, NREM, POA, VLPO
34  2004 A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. IL-1ra
35  2004 Corticotropin-releasing factor and interleukin-1beta are involved in the electroacupuncture-induced analgesic effect on inflammatory pain elicited by carrageenan. CRF, EA, EAA, i.pl, i.v, PPT
36  2004 Interleukin-1beta modulates state-dependent discharge activity of preoptic area and basal forebrain neurons: role in sleep regulation. BF, non-REM, POA, RA
37  2004 Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain. BBB, CNS
38  2003 Effect of tumour necrosis factor-alpha and interleukin 1beta on endothelium-dependent relaxation in rat mesenteric resistance arteries in vitro. ACh, BK, EDHF, HIS, L-NAME, L-NMMA, PE, SNP, SOD, TNF
39  2003 Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. HMGB1, i.c.v, TNF
40  2003 Hydrogen peroxide mediates interleukin-1beta-induced AP-1 activation in articular chondrocytes: implications for the regulation of iNOS expression. AP-1, iNOS, ROS
41  2002 Endogenous prostaglandin D2 synthesis reduces an increase in plasminogen activator inhibitor-1 following interleukin stimulation in bovine endothelial cells. EC, PAI, PGD2
42  2002 Interferon gamma antagonizes interleukin-1beta-induced cyclooxygenase-2 expression and prostaglandin E(2) production in human myometrial cells. COX-2, DMEM, FCS, IFN-gamma, IkappaB, NF-kappaB, TNF-alpha
43  2002 Role of mitogen-activated protein kinases and tyrosine kinases on IL-1-Induced NF-kappaB activation and iNOS expression in bovine articular chondrocytes. iNOS, MAPK, NO, PTK
44  2002 Role of nitric oxide in the activation of NF-kappaB, AP-1 and NOS II expression in articular chondrocytes. AP-1, NF-kappaB, NO, SNAP
45  2002 Statin enhances cytokine-mediated induction of nitric oxide synthesis in vascular smooth muscle cells. GTPCH, IFN, iNOS, NF, NO, VSMC
46  2001 A single administration of interleukin-1 or amphetamine induces long-lasting increases in evoked noradrenaline release in the hypothalamus and sensitization of ACTH and corticosterone responses in rats. ACTH, AVP, CRH, HPA, PVN
47  2001 Diphenyleneiodonium inhibits NF-kappaB activation and iNOS expression induced by IL-1beta: involvement of reactive oxygen species. DPI, iNOS, NF-kappaB, NO, ROS
48  2001 Effect of inflammatory cytokines on the metabolism of low-density lipoproteins by human vascular endothelial cells. AcLDL, BAECs, HuECs, TNF
49  2001 Effect of non-surgical periodontal therapy on C-telopeptide pyridinoline cross-links (ICTP) and interleukin-1 levels. BOP, CAL, ELISA, GCF, PD, RIA
50  2001 Interleukin-1beta-induced prostaglandin E2 production in human myometrial cells: role of a pertussis toxin-sensitive component. Cox-2, HMC, MAPK, NF-kappaB, PG, PTX
51  2001 Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines. HIV-1, TNF-alpha
52  2001 The role of cytokines in physiological sleep regulation. GFs, NREMS, TNF
53  2000 Changes of cytokine profiles during peritonitis in patients on continuous ambulatory peritoneal dialysis. CAPD, cDNA, FGF, PDE, TGF-beta
54  2000 Expression of IL-10 and GM-CSF in Blood Monocytes and Alveolar Macrophages. AMs, GM-CSF, IFN-gamma, PBMs, RANTES
55  2000 Inhibition by deacetylase inhibitors of IL-1-dependent induction of haptoglobin involves CCAAT/Enhancer-binding protein isoforms in intestinal epithelial cells. APR, TSA
56  2000 Interleukin-1beta-induced expression of monocyte chemotactic protein-1 in the rabbit retina: an in situ and immunohistochemical study. MCP-1, pi
57  2000 Islet protein expression changes during diabetes development in islet syngrafts in BB-DP rats and during rejection of BB-DP islet allografts. WK
58  2000 Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy. CFU, E. coli, ELISA
59  2000 Transcriptional regulation of cyclooxygenase-2 in the human microvascular endothelial cell line, HMEC-1: control by the combinatorial actions of AP2, NF-IL-6 and CRE elements. COX-2, EMSA
60  1999 An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta. NF-kappaB, TNF
61  1999 IL-1beta induces serine protease inhibitor 3 (SPI-3) gene expression in rat pancreatic beta-cells. Detection by differential display of messenger RNA. DDRT-PCR, iNOS, SPI-3
62  1999 Interleukin-1beta-induced release of matrix proteins into culture media causes inhibition of mineralization of nodules formed by periodontal ligament cells in vitro. AA, ALP, BSP, DEX, DMEM, FBS, GP, OC, OPN, PDL, SPARC
63  1999 Role of ceramide in lipopolysaccharide (LPS)-induced signaling. LPS increases ceramide rather than acting as a structural homolog. ERKs, JNK, LPS, TNF
64  1999 The influence of interleukin-1 receptor antagonist transgene on spiral ganglion neurons. IL-1ra
65  1998 An accessory role for ceramide in interleukin-1beta induced prostaglandin synthesis. COX-1, COX-2, cPLA2, PGE2
66  1998 Area postrema removal abolishes stimulatory effects of intravenous interleukin-1beta on hypothalamic-pituitary-adrenal axis activity and c-fos mRNA in the hypothalamic paraventricular nucleus. ACTH, AP, i.v, NTS, PVN
67  1998 Bone mineral density in prepubertal children with beta-thalassemia: correlation with growth and hormonal data. BMI, CSS, GH, HSDS, IGF-I, IGFBP-3, PTH, TNF-alpha
68  1998 Cytokine mRNA expression in whole blood samples from dogs with natural canine distemper virus infection. CDV, IFN, IL-12, IL-6, IL-8, RT-PCR, TNF
69  1998 Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets. HSP70, IkappaB, NF-kappaB
70  1998 LPS-induced cytokine production and expression of beta2-integrins and CD14 by peripheral blood mononuclear cells of patients with homozygous familial hypercholesterolemia. FH, TNF
71  1998 Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes. bFGF, iNOS, MMPs, NO
72  1998 Temporal and spatial patterns of c-fos mRNA induced by intravenous interleukin-1: a cascade of non-neuronal cellular activation at the blood-brain barrier. GFAP
73  1997 Corticosteroids alter hematopoiesis in vitro by enhancing human monocyte secretion of granulocyte colony-stimulating factor. BM, CFU-GM, GM-CSF, HCS, TNF
74  1997 Cytokine treatment of endothelial cells increases glycoprotein Ib alpha-dependent adhesion to von Willebrand factor. EC, GPIbalpha, HUVEC, IFN-gamma, MoAb, TNF-alpha, vWF, WT-vWF
75  1997 Effect of azelastine on PGE2 production in fibroblasts in normal skin. The possibility of inhibition of inducible cyclooxygenase by azelastine. PGE2
76  1997 Exposure to alcohol in utero blunts splenic sympathetic neural response to endotoxin and interleukin-1beta in the rat. FAE, NE
77  1997 Human lung mononuclear cells induce nitric oxide synthase in murine airway epithelial cells in vitro: role of TNFalpha and IL-1beta. iNOS, M-CM, NO, TNF
78  1997 In-vitro modulation of plasminogen activator activity, prostaglandin E and nitric oxide production by interleukin-1 in pregnant mare serum gonadotrophin-primed theca-interstitial cells. NO, PA, PGE, PMSG, T-I, TGF
79  1997 Modulation of glutathione S-transferase subunits A2, M1, and P1 expression by interleukin-1beta in rat hepatocytes in primary culture. GSTs
80  1997 Oxidative stress increases hepatocyte iNOS gene transcription and promoter activity. iNOS
81  1997 Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells. LO, VSMC
82  1997 Sensitization of human umbilical vein endothelial cells to Shiga toxin: involvement of protein kinase C and NF-kappaB. AMG, HUVEC, LPS, PKC, PMA, TNF, TPCK
83  1997 Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB. IVGF, MnSOD, TNF, TNFRE
84  1996 Expression of corticotropin-releasing factor in inflamed tissue is required for intrinsic peripheral opioid analgesia. CRF, CWS
85  1996 Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1. ARDS, BAL, TNF
86  1996 Regulation of nerve growth factor mRNA by interleukin-1 in rat hippocampal astrocytes is mediated by NFkappaB. ---
87  1996 Transcriptional downregulation of stromelysin by tetracycline. AP-1
88  1992 Endotoxin or cytokines attenuate ozone-induced DNA synthesis in rat nasal transitional epithelium. i.p, NTE, TNF