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Abbreviation : IL-5
Long Form : interleukin-5
No. Year Title Co-occurring Abbreviation
2020 A Comprehensive Evaluation of Mepolizumab Effectiveness in a Real-Life Setting. ---
2020 A randomized, placebo-controlled, double-blind pilot study of single-dose humanized anti-IL5 antibody (reslizumab) for the reduction of eosinophilia following diethylcarbamazine treatment of Loa loa infection. AEC, DEC, mf
2020 Altered plasma cytokine levels in acute and chronic central serous chorioretinopathy. CSC, CT, IL-6, TNF-alpha, VEGF
2020 Beliefs and preferences regarding biological treatments for severe asthma. INESNET
2020 Benralizumab as a steroid-sparing treatment option in eosinophilic granulomatosis with polyangiitis. EGPA, IL-5R
2020 Citrus flavonoids suppress IL-5 and ROS through distinct pathways in PMA/ionomycin-induced EL-4 cells. ---
2020 Correlation of mucus inflammatory proteins and olfaction in chronic rhinosinusitis. CCL2, CRS, CRSsNP, CRSwNP, CT, CXCL5, IgE, OC, TDI, TNF-alpha
2020 Correlation of Nasal Fluid Biomarkers and Symptoms in Patients with Persistent Allergic Rhinitis. ARIA, CC16, ELISA, NALF, PAR, TNSS
2020 Customizable Multiplex Antibody Array Immunoassays with Attomolar Sensitivities. ELISA, IL-10, IL-22, IL-6, TNF-alpha
10  2020 Distinct immune phenotypes in infants developing asthma during childhood. ---
11  2020 Effectiveness and safety of benralizumab for severe asthma in clinical practice (J-BEST): a prospective study. ACT, AQLQ, FeNO, FEV1, OCS
12  2020 Effects of interferon and glatiramer acetate on cytokine patterns in multiple sclerosis patients. GA, IFN-gamma, MS, RR, TGF-beta
13  2020 Evaluation of C-C Chemokine Ligand 5 (CCL5) Chemokine, Interleukin 5 (IL-5) Cytokine, and Eosinophil Counts as Potential Biomarkers in Saudi Patients with Chronic Asthma During Sandstorms. CCL5, ELISA, IgE
14  2020 Identification of serum biomarker panel to differentiate malignant from benign thyroid nodules using multiplex bead assay. AUC, EGF, HGF, IL-8, VDRP
15  2020 Immune Response in Young Thoroughbred Racehorses under Training. Hct, IFN-gamma, IL-1beta, IL-2, IL-3, IL-4, IL-6, IL-8, MCH, MCHC, MCV, RDW-SD, TGF-beta, TNF-alpha
16  2020 Interleukin-5 deletion promotes sepsis-induced M1 macrophage differentiation, deteriorates cardiac dysfunction, and exacerbates cardiac injury via the NF-kappaB p65 pathway in mice. LPS, NF-kappaB
17  2020 Interleukin-5-producing malignant pleural mesothelioma with eosinophilic pleural effusion. ---
18  2020 Longitudinal analyses reveal immunological misfiring in severe COVID-19. COVID-19
19  2020 Massive atelectasis by mucoid impaction in an asthma patient during treatment with anti-interleukin-5 receptor antibody. ---
20  2020 Mepolizumab: an alternative therapy for idiopathic chronic eosinophilic pneumonia with glucocorticoid intolerance. ICEP
21  2020 Mesenchymal PGD2 activates an ILC2-Treg axis to promote proliferation of normal and malignant HSPCs. AML, COX, HSPCs, MSCs, PGs
22  2020 Nicotinamide inhibits melanoma in vitro and in vivo. ATP, IFN, IFN-gamma, IL-10, IL-3, NAM, RANTES, ROS
23  2020 Particle depletion of diesel exhaust restores allergen-induced lung-protective surfactant protein D in human lungs. BAL, CC16, DE, PDDE, SP-D
24  2020 PD-1 expression affects cytokine production by ILC2 and is influenced by peroxisome proliferator-activated receptor-gamma. ILCs, PPARgamma
25  2020 Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis. EGPA
26  2020 Potential anti-inflammatory and immunomodulatory effects of carvacrol against ovalbumin-induced asthma in rats. AEC, BALF, DEXA, IFN-gamma, IgE, IL-13, IL-4, iNOS, MDA, OVA, SOD, TNF-alpha
27  2020 Real-Life effects of benralizumab on exacerbation number and lung hyperinflation in atopic patients with severe eosinophilic asthma. ---
28  2020 Real-life experience with benralizumab during 6 months. ACT
29  2020 Selective AhR knockout in langerin-expressing cells abates Langerhans cells and polarizes Th2/Tr1 in epicutaneous protein sensitization. AhR, DC, IgE, IL-13, LC, LN, Th2, Tr1
30  2020 Significant improvement in lung function and asthma control after benralizumab treatment for severe refractory eosinophilic asthma. ACQ, CRSwNP, OCS, SRA, TSLP
31  2020 Surface-modified mesoporous nanofibers for microfluidic immunosensor with an ultra-sensitivity and high signal-to-noise ratio. OPA, PEO-PPO-PEO
32  2020 The Current State of Biologic Therapies for Treatment of Refractory Asthma. FDA, IgE
33  2020 Usefulness of lymphocyte transformation test and in vitro cytokine release in differentiating between independent and cross-reacting nickel/palladium allergy. LTT, Ni, Pd, PT
34  2020 Zoledronic Acid Abrogates Restraint Stress-Induced Macrophage Infiltration, PDGF-AA Expression, and Ovarian Cancer Growth. GM-CSF, MIF, PDGF-AA, TfR, VEGF
35  2020 [Effect of Huai Qi Huang on asthma in rats and the mechanism research]. BALF, HQH, IgE, IL-10, IL-3, IL-4, INF-gamma
36  2019 Active vaccination against interleukin-5 as long-term treatment for insect-bite hypersensitivity in horses. eIL-5, IBH, VLP
37  2019 Application of Inflammatory Markers in Induced Sputum in Stable Chronic Obstructive Pulmonary Disease Patients with Positive Bronchodilation Tests. BD, COPD, ECP, MPO
38  2019 Chemokines and Growth Factors Produced by Lymphocytes in the Incompetent Great Saphenous Vein. CVD, FGF, G-CSF, GFs, GM-CSF, GSV, IL-8, MCP-1, MIP-1A and MIP-1B, PDGF-BB, PHA, VEGF
39  2019 Chronic, Active Inflammation in Patients With Failed Total Knee Replacements Undergoing Revision Surgery. GM-CSF, OA, SF, TKA
40  2019 Cyanidin-3-O-beta-glucoside attenuates allergic airway inflammation by modulating the IL-4Ralpha-STAT6 signaling pathway in a murine asthma model. BALF, Cy-3-g, IL-13, IL-4, IL-4Ralpha, OVA, STAT6, Th2
41  2019 Effectiveness and safety of mepolizumab in severe refractory eosinophilic asthma: results in clinical practice. OCS
42  2019 Effects of catalpol on bronchial asthma and its relationship with cytokines. BALF, IFN-gamma, IL-4
43  2019 Effects of miR-26a/miR-146a/miR-31 on airway inflammation of asthma mice and asthma children. ELISA, miR-26a, RT-PCR, TNF-alpha
44  2019 Efficacy and safety of mepolizumab in a real-world cohort of patients with severe eosinophilic asthma. OCS
45  2019 Efficacy and steroid-sparing effect of benralizumab: has it an advantage over its competitors? HRQoL, OCS
46  2019 Evaluation of Immunogenic Effect of Toxoplasma gondii Recombinant SAG-1 Antigen with Propranolol as Adjuvant in BALB/c Mice. IFN-gamma, rSAG-1, TLA
47  2019 Genome-Wide Scan Identifies Selection Signatures in Chinese Wagyu Cattle Using a High-Density SNP Array. ADAM12, ALAS1, CAPN1, FAM110A, FGF14, GO, GRIK2, HSD17B7, IGF2R, LHX6, NOS1AP, PAX6, PRDM9, QTL, RORA, RPAP3, RXFP4, SMIM13, SNX29, TAFA1, TLR9, WDR7, ZIM2
48  2019 Higher Binding Affinity and in vitro Potency of Reslizumab for Interleukin-5 Compared With Mepolizumab. ---
49  2019 IL-5 Exposure In Utero Increases Lung Nerve Density and Airway Reactivity in Adult Offspring. ---
50  2019 Inhibitory effects of catalpol coordinated with budesonide and their relationship with cytokines and Interleukin-13 expression. BALF, BUD, IFN-gamma, IL-13, IL-4
51  2019 Interleukin-5 in the Pathophysiology of Severe Asthma. ---
52  2019 Maternal deprivation increases microglial activation and neuroinflammatory markers in the prefrontal cortex and hippocampus of infant rats. CD11B, INF-gamma, MD, MIP, PFC, PND, TLR
53  2019 Mepolizumab for the treatment of eosinophilic granulomatosis with polyangiitis. ANCA, EGPA
54  2019 Mepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease. ---
55  2019 Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma. GINA, IgE, IL-4Ralpha, IL-5R, OCS
56  2019 Protective effects of betulinic acid on intestinal mucosal injury induced by cyclophosphamide in mice. BA, CYP, MDA, MIP-1alpha, MIP-1beta, RANTES, SOD, TNF-alpha, ZO-1
57  2019 Protective effects of betulinic acid on intestinal mucosal injury induced by cyclophosphamide in mice. BA, CYP, MDA, RANTES, SOD, TNF-alpha, ZO-1
58  2019 Pulegone inhibits inflammation via suppression of NLRP3 inflammasome and reducing cytokine production in mice. GM-CSF, IFN-gamma, IL-18, IL-1beta, LPS, M-CSF, MCP-1, MIP-1beta, NLRP3, TNF-alpha
59  2019 Real-life rapidity of benralizumab effects in patients with severe allergic eosinophilic asthma: Assessment of blood eosinophils, symptom control, lung function and oral corticosteroid intake after the first drug dose. ACT, ADCC, FEV1, OCS, PEF
60  2019 Role of coaggregation in the pathogenicity and prolonged colonisation of Vibrio cholerae. AI-2, IL-10
61  2019 Safety and Efficacy of Mepolizumab in Patients with Eosinophilic Granulomatosis with Polyangiitis. EGPA
62  2019 Selection and characterization of single-stranded DNA aptamers against interleukin-5. SELEX
63  2019 Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic Asthma: A Short Report. FeNO, IL-25, SNEA, TSLP
64  2019 Single-cell Analysis of CAR-T Cell Activation Reveals A Mixed TH1/TH2 Response Independent of Differentiation. CAR, GM-CSF, Th
65  2019 Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121. ---
66  2019 The ethanol extract of Involcucrum castaneae ameliorated ovalbumin-induced airway inflammation and smooth muscle thickening in guinea pigs. BALF, EEIC, ELISA, EOS, IC, IFN-gamma, IgE, NGF, OVA, PB, RT-PCR
67  2019 The relationship between inflammatory markers and spirometric parameters in ACOS, Asthma, and COPD. COPD, CysLTs, PGD2, PGE2
68  2019 Toll-like receptor 4 activation on human amniotic epithelial cells is a risk factor for pregnancy loss. hAECs, LPS, PGE2, TGF-beta1, TLRs, TNF-alpha
69  2019 Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program. EoPs, GMP, HSCs, Trib1
70  2019 World Health Organization-defined eosinophilic disorders: 2019 update on diagnosis, risk stratification, and management. CEL, NOS, HES
71  2019 [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. ---
72  2019 [Clinical and economic analysis of Reslizumab use in the treatment of patients with severe allergic eosinophilic asthma]. mAb
73  2019 [Expression of immunological and inflammatory biomarkers in chronic rhinosinusitis with nasal polyps and its predictive value for recurrence]. CRSwNP, ECP/MPO, ROC, TIMP1
74  2019 [Levels of airway inflammatory mediators in peripheral blood in infants and young children with wheezing]. EOS, IL-13, IL-2, IL-4, TGF-beta1, Th1, Th2, tIgE
75  2019 [The protective effect of interleukin-5 in septic mice]. BUN, cTnI, SCr, TNF-alpha
76  2018 Activation state of circulating eosinophils in nasal polyposis. CRSwNP, MFI
77  2018 Anti-IL-5 and IL-5Ra: Efficacy and Safety of New Therapeutic Strategies in Severe Uncontrolled Asthma. ---
78  2018 Anti-IL-5 therapy in patients with severe eosinophilic asthma - clinical efficacy and possible criteria for treatment response. ---
79  2018 Benralizumab for the add-on maintenance treatment of patients with severe asthma aged 12years and older with an eosinophilic phenotype. ---
80  2018 Benralizumab: From the Basic Mechanism of Action to the Potential Use in the Biological Therapy of Severe Eosinophilic Asthma. FDA, Th2
81  2018 Bone marrow type 2 innate lymphoid cells: a local source of interleukin-5 in interleukin-33-driven eosinophilia. ---
82  2018 Characterisation of the porcine cytokines which activate the CD131betac common sub-unit, for potential immune-augmentation. 5-FU, BM, GM-CSF, HSC, IL-3, IM, po, rPo
83  2018 Characterizing the course of suicidal ideation response to ketamine. MDD, SI
84  2018 Efficacy, adverse events, and inter-drug comparison of mepolizumab and reslizumab anti-IL-5 treatments of severe asthma - a systematic review and meta-analysis. MCID, OCS
85  2018 EPO modified MSCs can inhibit asthmatic airway remodeling in an animal model. BALF, EPO, IL-13, IL-4, MSCs, p38 MAPK, TAK1, TGF-beta1
86  2018 Expressions of Eotaxin-3, Interleukin-5, and Eosinophil-Derived Neurotoxin in Chronic Subdural Hematoma Fluids. CSDHs, CSF, EDN
87  2018 Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement. CRSwNP
88  2018 Host- and Helminth-Derived Endocannabinoids That Have Effects on Host Immunity Are Generated during Infection. 2-AG, AEA, OEA
89  2018 Human Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Atopic Dermatitis by Regulating the Expression of MIP-2, miR-122a-SOCS1 Axis, and Th1/Th2 Responses. AD, AD-MSCs, CD163, HDAC3, iNOS, MCs, MIP-1ss, SOCS1, Th1, Th2, Treg
90  2018 Identification of Adult Mesodermal Progenitor Cells and Hierarchy in Atherosclerotic Vascular Calcification. BM, IL-1beta
91  2018 IFN-gamma and IL-5 whole blood response directed against mycolactone polyketide synthase domains in patients with Mycobacterium ulcerans infection. ACP3, Ag85A, IFN-gamma, KS C, PKS, RPMI
92  2018 Interleukin-5 suppresses Vascular Endothelial Growth Factor-induced angiogenesis through STAT5 signaling. HMVEC-L, KD
93  2018 Membrane Vesicles Derived from Bordetella bronchiseptica: Active Constituent of a New Vaccine against Infections Caused by This Pathogen. OmpC, OMVs
94  2018 Mepolizumab for the treatment of eosinophilic granulomatosis with polyangiitis. ANCA, EGPA
95  2018 Real-life evaluation of the clinical, functional, and hematological effects of mepolizumab in patients with severe eosinophilic asthma: Results of a single-centre observational study. ACT
96  2018 RORalpha-expressing T regulatory cells restrain allergic skin inflammation. DR3, RORalpha, Th2, TL1A, TNF
97  2018 Targeting the Interleukin-5 Pathway for Treatment of Eosinophilic Conditions Other than Asthma. IL-5Ralpha
98  2018 The Prospects of an Active Vaccine Against Asthma Targeting IL-5. mAbs
99  2018 TSLP signaling in CD4+ T cells programs a pathogenic T helper 2 cell state. Th2, TSLP
100  2017 Anti-IL5 therapies for asthma. ACQ, AQLQ, HRQoL, ICS, IL-5R, SGRQ