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Abbreviation : IL-5
Long Form : interleukin-5
No. Year Title Co-occurring Abbreviation
2020 Citrus flavonoids suppress IL-5 and ROS through distinct pathways in PMA/ionomycin-induced EL-4 cells. ---
2020 Correlation of Nasal Fluid Biomarkers and Symptoms in Patients with Persistent Allergic Rhinitis. ARIA, CC16, ELISA, NALF, PAR, TNSS
2020 Distinct immune phenotypes in infants developing asthma during childhood. ---
2020 Effects of interferon and glatiramer acetate on cytokine patterns in multiple sclerosis patients. GA, IFN-gamma, MS, RR, TGF-beta
2020 PD-1 expression affects cytokine production by ILC2 and is influenced by peroxisome proliferator-activated receptor-gamma. ILCs, PPARgamma
2020 Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis. EGPA
2020 Potential anti-inflammatory and immunomodulatory effects of carvacrol against ovalbumin-induced asthma in rats. AEC, BALF, DEXA, IFN-gamma, IgE, IL-13, IL-4, iNOS, MDA, OVA, SOD, TNF-alpha
2020 The Current State of Biologic Therapies for Treatment of Refractory Asthma. FDA, IgE
2020 [Effect of Huai Qi Huang on asthma in rats and the mechanism research]. BALF, HQH, IgE, IL-10, IL-3, IL-4, INF-gamma
10  2019 Active vaccination against interleukin-5 as long-term treatment for insect-bite hypersensitivity in horses. eIL-5, IBH, VLP
11  2019 Application of Inflammatory Markers in Induced Sputum in Stable Chronic Obstructive Pulmonary Disease Patients with Positive Bronchodilation Tests. BD, COPD, ECP, MPO
12  2019 Chemokines and Growth Factors Produced by Lymphocytes in the Incompetent Great Saphenous Vein. CVD, FGF, G-CSF, GFs, GM-CSF, GSV, IL-8, MCP-1, MIP-1A and MIP-1B, PDGF-BB, PHA, VEGF
13  2019 Chronic, Active Inflammation in Patients With Failed Total Knee Replacements Undergoing Revision Surgery. GM-CSF, OA, SF, TKA
14  2019 Correlation of mucus inflammatory proteins and olfaction in chronic rhinosinusitis. CCL2, CRS, CRSsNP, CRSwNP, CT, CXCL5, IgE, OC, TDI, TNF-alpha
15  2019 Cyanidin-3-O-beta-glucoside attenuates allergic airway inflammation by modulating the IL-4Ralpha-STAT6 signaling pathway in a murine asthma model. BALF, Cy3G, IL-13, IL-4, IL-4Ralpha, OVA, STAT6, Th2
16  2019 Effectiveness and safety of mepolizumab in severe refractory eosinophilic asthma: results in clinical practice. OCS
17  2019 Effects of catalpol on bronchial asthma and its relationship with cytokines. BALF, IFN-gamma, IL-4
18  2019 Effects of miR-26a/miR-146a/miR-31 on airway inflammation of asthma mice and asthma children. ELISA, miR-26a, RT-PCR, TNF-alpha
19  2019 Efficacy and safety of mepolizumab in a real-world cohort of patients with severe eosinophilic asthma. OCS
20  2019 Efficacy and steroid-sparing effect of benralizumab: has it an advantage over its competitors? HRQoL, OCS
21  2019 Evaluation of Immunogenic Effect of Toxoplasma gondii Recombinant SAG-1 Antigen with Propranolol as Adjuvant in BALB/c Mice. IFN-gamma, rSAG-1, TLA
22  2019 Genome-Wide Scan Identifies Selection Signatures in Chinese Wagyu Cattle Using a High-Density SNP Array. ADAM12, ALAS1, CAPN1, FAM110A, FGF14, GO, GRIK2, HSD17B7, IGF2R, LHX6, NOS1AP, PAX6, PRDM9, QTL, RORA, RPAP3, RXFP4, SMIM13, SNX29, TAFA1, TLR9, WDR7, ZIM2
23  2019 Higher Binding Affinity and in vitro Potency of Reslizumab for Interleukin-5 Compared With Mepolizumab. ---
24  2019 IL-5 Exposure in utero Increases Lung Nerve Density and Causes Airway Reactivity in Adult Offspring. ---
25  2019 Inhibitory effects of catalpol coordinated with budesonide and their relationship with cytokines and Interleukin-13 expression. BALF, BUD, IFN-gamma, IL-13, IL-4
26  2019 Interleukin-5 in the Pathophysiology of Severe Asthma. ---
27  2019 Maternal deprivation increases microglial activation and neuroinflammatory markers in the prefrontal cortex and hippocampus of infant rats. CD11B, INF-gamma, MD, MIP, PFC, PND, TLR
28  2019 Mepolizumab for the treatment of eosinophilic granulomatosis with polyangiitis. ANCA, EGPA
29  2019 Mepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease. ---
30  2019 Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma. GINA, IgE, IL-4Ralpha, IL-5R, OCS
31  2019 Protective effects of betulinic acid on intestinal mucosal injury induced by cyclophosphamide in mice. BA, CYP, MDA, MIP-1alpha, MIP-1beta, RANTES, SOD, TNF-alpha, ZO-1
32  2019 Protective effects of betulinic acid on intestinal mucosal injury induced by cyclophosphamide in mice. BA, CYP, MDA, RANTES, SOD, TNF-alpha, ZO-1
33  2019 Pulegone inhibits inflammation via suppression of NLRP3 inflammasome and reducing cytokine production in mice. GM-CSF, IFN-gamma, IL-18, IL-1beta, LPS, M-CSF, MCP-1, MIP-1beta, NLRP3, TNF-alpha
34  2019 Real-life rapidity of benralizumab effects in patients with severe allergic eosinophilic asthma: Assessment of blood eosinophils, symptom control, lung function and oral corticosteroid intake after the first drug dose. ACT, ADCC, FEV1, OCS, PEF
35  2019 Role of coaggregation in the pathogenicity and prolonged colonisation of Vibrio cholerae. AI-2, IL-10
36  2019 Safety and Efficacy of Mepolizumab in Patients with Eosinophilic Granulomatosis with Polyangiitis. EGPA
37  2019 Selection and characterization of single-stranded DNA aptamers against interleukin-5. SELEX
38  2019 Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic Asthma: A Short Report. FeNO, IL-25, SNEA, TSLP
39  2019 Single-cell Analysis of CAR-T Cell Activation Reveals A Mixed TH1/TH2 Response Independent of Differentiation. CAR, GM-CSF, Th
40  2019 Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121. ---
41  2019 The ethanol extract of Involcucrum castaneae ameliorated ovalbumin-induced airway inflammation and smooth muscle thickening in guinea pigs. BALF, EEIC, ELISA, EOS, IC, IFN-gamma, IgE, NGF, OVA, PB, RT-PCR
42  2019 The relationship between inflammatory markers and spirometric parameters in ACOS, Asthma, and COPD. COPD, CysLTs, PGD2, PGE2
43  2019 Toll-like receptor 4 activation on human amniotic epithelial cells is a risk factor for pregnancy loss. hAECs, LPS, PGE2, TGF-beta1, TLRs, TNF-alpha
44  2019 Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program. EoPs, GMP, HSCs, Trib1
45  2019 World Health Organization-defined eosinophilic disorders: 2019 update on diagnosis, risk stratification, and management. CEL, NOS, HES
46  2019 [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. ---
47  2019 [Expression of immunological and inflammatory biomarkers in chronic rhinosinusitis with nasal polyps and its predictive value for recurrence]. CRSwNP, ECP/MPO, ROC, TIMP1
48  2019 [Levels of airway inflammatory mediators in peripheral blood in infants and young children with wheezing]. EOS, IL-13, IL-2, IL-4, TGF-beta1, Th1, Th2, tIgE
49  2019 [The protective effect of interleukin-5 in septic mice]. BUN, cTnI, SCr, TNF-alpha
50  2018 Activation state of circulating eosinophils in nasal polyposis. CRSwNP, MFI
51  2018 Anti-IL-5 and IL-5Ra: Efficacy and Safety of New Therapeutic Strategies in Severe Uncontrolled Asthma. ---
52  2018 Anti-IL-5 therapy in patients with severe eosinophilic asthma - clinical efficacy and possible criteria for treatment response. ---
53  2018 Benralizumab for the add-on maintenance treatment of patients with severe asthma aged 12years and older with an eosinophilic phenotype. ---
54  2018 Benralizumab: From the Basic Mechanism of Action to the Potential Use in the Biological Therapy of Severe Eosinophilic Asthma. FDA, Th2
55  2018 Bone marrow type 2 innate lymphoid cells: a local source of interleukin-5 in interleukin-33-driven eosinophilia. ---
56  2018 Characterisation of the porcine cytokines which activate the CD131betac common sub-unit, for potential immune-augmentation. 5-FU, BM, GM-CSF, HSC, IL-3, IM, po, rPo
57  2018 Characterizing the course of suicidal ideation response to ketamine. MDD, SI
58  2018 Efficacy, adverse events, and inter-drug comparison of mepolizumab and reslizumab anti-IL-5 treatments of severe asthma - a systematic review and meta-analysis. MCID, OCS
59  2018 EPO modified MSCs can inhibit asthmatic airway remodeling in an animal model. BALF, EPO, IL-13, IL-4, MSCs, p38 MAPK, TAK1, TGF-beta1
60  2018 Expressions of Eotaxin-3, Interleukin-5, and Eosinophil-Derived Neurotoxin in Chronic Subdural Hematoma Fluids. CSDHs, CSF, EDN
61  2018 Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement. CRSwNP
62  2018 Host- and Helminth-Derived Endocannabinoids That Have Effects on Host Immunity Are Generated during Infection. 2-AG, AEA, OEA
63  2018 Human Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Atopic Dermatitis by Regulating the Expression of MIP-2, miR-122a-SOCS1 Axis, and Th1/Th2 Responses. AD, ADMSCs, CD163, HDAC3, iNOS, MCs, MIP-1ss, SOCS1, Th1, Th2, Treg
64  2018 Identification of Adult Mesodermal Progenitor Cells and Hierarchy in Atherosclerotic Vascular Calcification. BM, IL-1beta
65  2018 IFN-gamma and IL-5 whole blood response directed against mycolactone polyketide synthase domains in patients with Mycobacterium ulcerans infection. ACP3, Ag85A, IFN-gamma, KS C, PKS, RPMI
66  2018 Interleukin-5 suppresses Vascular Endothelial Growth Factor-induced angiogenesis through STAT5 signaling. HMVEC-L, KD
67  2018 Membrane Vesicles Derived from Bordetella bronchiseptica: Active Constituent of a New Vaccine against Infections Caused by This Pathogen. OmpC, OMVs
68  2018 Mepolizumab for the treatment of eosinophilic granulomatosis with polyangiitis. ANCA, EGPA
69  2018 Real-life evaluation of the clinical, functional, and hematological effects of mepolizumab in patients with severe eosinophilic asthma: Results of a single-centre observational study. ACT
70  2018 RORalpha-expressing T regulatory cells restrain allergic skin inflammation. DR3, RORalpha, Th2, TL1A, TNF
71  2018 Targeting the Interleukin-5 Pathway for Treatment of Eosinophilic Conditions Other than Asthma. IL-5Ralpha
72  2018 The Prospects of an Active Vaccine Against Asthma Targeting IL-5. mAbs
73  2018 TSLP signaling in CD4+ T cells programs a pathogenic T helper 2 cell state. Th2, TSLP
74  2017 Anti-IL5 therapies for asthma. ACQ, AQLQ, HRQoL, ICS, IL-5R, SGRQ
75  2017 Anti-Interleukin 5 (IL-5) and IL-5Ra Biological Drugs: Efficacy, Safety, and Future Perspectives in Severe Eosinophilic Asthma. IL-5Ra
76  2017 Bach2 Controls Homeostasis of Eosinophils by Restricting the Type-2 Helper Function of T Cells. WT
77  2017 Benralizumab for the treatment of asthma. ---
78  2017 Cytokine Profiles in Malawian Children Presenting with Uncomplicated Malaria, Severe Malarial Anemia, and Cerebral Malaria. CM, IFN-gamma, SMA, TNF-alpha, UCM
79  2017 Cytokines affecting CD4+T regulatory cells in transplant tolerance. III. Interleukin-5 (IL-5) promotes survival of alloantigen-specific CD4+ T regulatory cells. IL-5Ralpha, rIL-5
80  2017 Eosinophil Cationic Protein in Patients with Differentiated Thyroid Cancer Treated with Radioactive Iodine 131. DTC, ECP, ELISA, FIA, HT, IL-13, IL-4, Th2
81  2017 Genipin inhibits allergic responses in ovalbumin-induced asthmatic mice. AHR, BALF, Ig, OVA
82  2017 IL-5 blocks apoptosis and tau hyperphosphorylation induced by Abeta25-35 peptide in PC12 cells. AD, NFTs
83  2017 IL33 and IL1RL1 variants are associated with asthma and atopy in a Brazilian population. eQTL, IL-13, IL-33, IL-4, sIgE, SPT, sST2
84  2017 Inhibition of interleukin-5 induced false positive anti-drug antibody responses against mepolizumab through the use of a competitive blocking antibody. ADA
85  2017 Integrated Cellular and Plasma Proteomics of Contrasting B-cell Cancers Reveals Common, Unique and Systemic Signatures. BL, CLL
86  2017 Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. AP-1, LTs, NF-kappaB, NFAT, TCR, Th2 cells
87  2017 Pharmacokinetic/pharmacodynamic drug evaluation of benralizumab for the treatment of asthma. hmAbs
88  2017 PPAR-gamma promotes type 2 immune responses in allergy and nematode infection. PPARgamma, Th2
89  2017 Proteomics of Eosinophil Activation. ---
90  2017 Reslizumab and Eosinophilic Asthma: One Step Closer to Precision Medicine? ---
91  2017 Reslizumab in Eosinophilic Asthma: A Review. ---
92  2017 Reslizumab in the treatment of inadequately controlled asthma in adults and adolescents with elevated blood eosinophils: clinical trial evidence and future prospects. ---
93  2017 Targeting Interleukin-5 in Patients With Severe Eosinophilic Asthma: A Clinical Review. ---
94  2017 The safety of mepolizumab for the treatment of asthma. ---
95  2017 World Health Organization-defined eosinophilic disorders: 2017 update on diagnosis, risk stratification, and management. CEL, NOS, HES
96  2017 [Effect of heat shock factor 1 on airway hyperresponsiveness and airway inflammation in mice with allergic asthma]. BALF, HMGB1, HSF1, IFN-gamma, IL-13, IL-4, OVA, p-JNK
97  2017 [Immunogenicity of recombinant analog of antitumor protein lactaptin]. KC, MIP-1
98  2017 [Therapeutic effects of histone deacetylase inhibitor givinostat on air inflammation and high airway resistance in a murine asthma model]. AHR, alpha-SMA, BALF, HDACi, IFN-gamma, IHC, IL-4, TGF-beta1
99  2016 Anti-arthritogenic effect of Saponin-1 by alteration of Th1/Th2 cytokine paradigm in arthritic mice. IFN-gamma, IL-2, IL-4, SAP-1
100  2016 Chromones: A Promising Ring System for New Anti-inflammatory Drugs. 5-LOX, COX