| 1 |
2020 |
Iron metabolic pathways in the processes of sponge plasticity. |
ADGB, IRP1, NGB |
| 2 |
2019 |
Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET. |
AGBE, IRP1, mRNAs |
| 3 |
2019 |
Regulation of cellular iron metabolism: Iron-dependent degradation of IRP by SCFFBXL5 ubiquitin ligase. |
--- |
| 4 |
2019 |
Relevance of the iron-responsive element (IRE) pseudotriloop structure for IRP1/2 binding and validation of IRE-like structures using the yeast three-hybrid system. |
ALAS2, EPAS1, FTL, IRE, IRPs, UTRs |
| 5 |
2018 |
Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin. |
5'-UTRs, APP, H-Ferritin, IC-ICP-MS, Mn, PD |
| 6 |
2018 |
Methods for Studying Iron Regulatory Protein 1: An Important Protein in Human Iron Metabolism. |
--- |
| 7 |
2018 |
Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3'-IRE stem-loops. |
3'-UTR, IRPs, TfR1 |
| 8 |
2018 |
The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia. |
DMT1, HIF-1alpha, HREs, IRP1, LDH |
| 9 |
2017 |
A drastic superoxide-dependent oxidative stress is prerequisite for the down-regulation of IRP1: Insights from studies on SOD1-deficient mice and macrophages treated with paraquat. |
IRP1, SOD1 |
| 10 |
2017 |
Effect of iron on cholesterol 7alpha-hydroxylase expression in alcohol-induced hepatic steatosis in mice. |
AFLD, CYP7A1, IRPs, UTRs |
| 11 |
2016 |
EGFR regulates iron homeostasis to promote cancer growth through redistribution of transferrin receptor 1. |
EGFR, IRPs, TfR1 |
| 12 |
2016 |
Transferrin receptor mRNA interactions contributing to iron homeostasis. |
IRPs |
| 13 |
2015 |
Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins. |
IRPs |
| 14 |
2015 |
Iron Regulatory Protein 1 Suppresses Hypoxia-Induced Iron Uptake Proteins Expression and Decreases Iron Levels in HepG2 Cells. |
DMT1, HIF-1, HREs, IRP1, LDH, LIP, UTR |
| 15 |
2015 |
SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1. |
IRPs |
| 16 |
2014 |
Electrophoretic mobility shift assay (EMSA) for the study of RNA-protein interactions: the IRE/IRP example. |
EMSA, UTRs |
| 17 |
2014 |
Hypoxia induced changes in expression of proteins involved in iron uptake and storage in cultured lens epithelial cells. |
HIF, HRE, IRP, LEC, ROS, TfR |
| 18 |
2014 |
Involvement of the iron regulatory protein from Eisenia andrei earthworms in the regulation of cellular iron homeostasis. |
IRPs, UTR |
| 19 |
2014 |
The IRP/IRE system in vivo: insights from mouse models. |
ALAS2, HIF2alpha, TfR1 |
| 20 |
2014 |
The physiological functions of iron regulatory proteins in iron homeostasis - an update. |
IRPs |
| 21 |
2013 |
Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function. |
IRP, IRP1 |
| 22 |
2012 |
Accommodating variety in iron-responsive elements: Crystal structure of transferrin receptor 1 B IRE bound to iron regulatory protein 1. |
Ftn H, IRPs |
| 23 |
2012 |
Mammalian iron metabolism and its control by iron regulatory proteins. |
--- |
| 24 |
2012 |
The bifunctional role of aconitase in Streptomyces viridochromogenes Tu494. |
IRPs |
| 25 |
2011 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin impairs iron homeostasis by modulating iron-related proteins expression and increasing the labile iron pool in mammalian cells. |
LIP, TCDD, TfR1 |
| 26 |
2011 |
Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide. |
Ft, IRPs |
| 27 |
2011 |
Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins. |
IRPs |
| 28 |
2011 |
Redox control of iron regulatory protein 2 stability. |
IRP2 |
| 29 |
2011 |
Two covariance models for iron-responsive elements. |
IRPs, UTRs |
| 30 |
2010 |
Iron regulatory proteins: from molecular mechanisms to drug development. |
IRPs |
| 31 |
2010 |
Multiple determinants within iron-responsive elements dictate iron regulatory protein binding and regulatory hierarchy. |
IRPs |
| 32 |
2009 |
Chlamydia trachomatis alters iron-regulatory protein-1 binding capacity and modulates cellular iron homeostasis in HeLa-229 cells. |
CT, IRP, TfR |
| 33 |
2009 |
Responsiveness of Trichomonas vaginalis to iron concentrations: evidence for a post-transcriptional iron regulation by an IRE/IRP-like system. |
UTRs |
| 34 |
2008 |
An iron responsive element-like stem-loop regulates alpha-hemoglobin-stabilizing protein mRNA. |
AHSP, IRPs, UTR |
| 35 |
2008 |
HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells. |
aa, HEK293, HOIL-1, IRP2 |
| 36 |
2008 |
Insights on regulation and function of the iron regulatory protein 1 (IRP1). |
ICS, IRP1 |
| 37 |
2008 |
Interaction of anthracyclines with iron responsive element mRNAs. |
IRPs |
| 38 |
2008 |
Iron-independent phosphorylation of iron regulatory protein 2 regulates ferritin during the cell cycle. |
IRP2 |
| 39 |
2008 |
Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice. |
TfR1 |
| 40 |
2008 |
The functional duality of iron regulatory protein 1. |
--- |
| 41 |
2007 |
Excess capacity of the iron regulatory protein system. |
TfR1 |
| 42 |
2007 |
Iron-dependent RNA-binding activity of Mycobacterium tuberculosis aconitase. |
ACN, ideR, IRPs, TCA, UTRs |
| 43 |
2007 |
Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation. |
DMT1, EMSA, EPO, IGF-I, IRP, SCF, TfR |
| 44 |
2007 |
Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts. |
IRP1, TfR1 |
| 45 |
2006 |
Crystal structure of human iron regulatory protein 1 as cytosolic aconitase. |
IRPs |
| 46 |
2006 |
Crystallization and preliminary X-ray diffraction analysis of iron regulatory protein 1 in complex with ferritin IRE RNA. |
IRP1 |
| 47 |
2006 |
Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy. |
IRPs |
| 48 |
2006 |
Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide. |
SNP, TfR |
| 49 |
2006 |
Of two cytosolic aconitases expressed in Drosophila, only one functions as an iron-regulatory protein. |
--- |
| 50 |
2006 |
Role of HIF-1 in iron regulation: potential therapeutic strategy for neurodegenerative disorders. |
HIF, HO-1, HREs, IRPs, TfR |
| 51 |
2006 |
Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA. |
IRP1, mRNAs |
| 52 |
2006 |
The role of iron regulatory proteins in mammalian iron homeostasis and disease. |
--- |
| 53 |
2006 |
[The role of iron regulatory proteins (IRPs) in the regulation of systemic iron homeostasis: lessons from studies on IRP1 and IRP2 knock out mice]. |
IRPs, UTR |
| 54 |
2005 |
Divalent metal transporter 1. |
DMT1 |
| 55 |
2005 |
Increased IRP1 activity in Friedreich ataxia. |
FRDA, ISC |
| 56 |
2004 |
A characterization of the activities of iron regulatory protein 1 in various farm animal species. |
IRP1 |
| 57 |
2004 |
Crassostrea gigas ferritin: cDNA sequence analysis for two heavy chain type subunits and protein purification. |
cDNA, EST, RACE, UTRs |
| 58 |
2004 |
Detection of intracellular iron by its regulatory effect. |
IRPs, NGAL |
| 59 |
2004 |
Iron metabolism and the IRE/IRP regulatory system: an update. |
--- |
| 60 |
2003 |
A high-capacity RNA affinity column for the purification of human IRP1 and IRP2 overexpressed in Pichia pastoris. |
--- |
| 61 |
2003 |
A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation. |
IRP1 |
| 62 |
2003 |
Effects of iron regulatory protein regulation on iron homeostasis during hypoxia. |
DMT1, Ft, mAco, TfR, UTR |
| 63 |
2003 |
Identification of two novel mutations in the 5'-untranslated region of H-ferritin using denaturing high performance liquid chromatography scanning. |
5'UTR, HPLC |
| 64 |
2003 |
Nitric oxide and peroxynitrite promote complete disruption of the [4Fe-4S] cluster of recombinant human iron regulatory protein 1. |
IRP1, SOD |
| 65 |
2003 |
Role of nitric oxide in cellular iron metabolism. |
IFN-gamma, LPS, TfR, UTR |
| 66 |
2002 |
An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript. |
5'-UTR, APP, IRP |
| 67 |
2002 |
Cloning and molecular characterization of two mosquito iron regulatory proteins. |
IRPs |
| 68 |
2002 |
Conditional derepression of ferritin synthesis in cells expressing a constitutive IRP1 mutant. |
IRP1 |
| 69 |
2002 |
Down-regulation of liver iron-regulatory protein 1 in haemochromatosis. |
HH, IRPs |
| 70 |
2002 |
Erythroblast iron metabolism in sideroblastic and sideropenic states. |
ACD, IDA, IRPs, sTfR, TfR |
| 71 |
2002 |
Hereditary hyperferritinaemia/ cataract syndrome. |
HHCS, IRPs, UTRs |
| 72 |
2002 |
Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level. |
DFO, IRPs, TfR, TfR2, UTR |
| 73 |
2002 |
Nitric oxide-mediated modulation of iron regulatory proteins: implication for cellular iron homeostasis. |
IFN-gamma, LPS, TfR, UTR |
| 74 |
2002 |
Nitrogen monoxide-mediated control of ferritin synthesis: implications for macrophage iron homeostasis. |
NO, SNP |
| 75 |
2002 |
Pathogenesis of hyperferritinemia cataract syndrome. |
HHCS, IRE, UTRs |
| 76 |
2002 |
Recycling of RNA binding iron regulatory protein 1 into an aconitase after nitric oxide removal depends on mitochondrial ATP. |
IRPs, NO |
| 77 |
2002 |
The Brome mosaic virus subgenomic promoter hairpin is structurally similar to the iron-responsive element and functionally equivalent to the minus-strand core promoter stem-loop C. |
BMV, RdRp, sg |
| 78 |
2001 |
Iron: deficiencies and requirements. |
IRPs |
| 79 |
2001 |
IRP1 activation by extracellular oxidative stress in the perfused rat liver. |
--- |
| 80 |
2001 |
Modulation of cellular iron metabolism by hydrogen peroxide. Effects of H2O2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts. |
IRP, TfR |
| 81 |
2001 |
Regulation of the 75-kDa subunit of mitochondrial complex I by iron. |
--- |
| 82 |
2001 |
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. |
IRPs, TFRC |
| 83 |
2001 |
The intracellular location of iron regulatory proteins is altered as a function of iron status in cell cultures and rat brain. |
IRPs |
| 84 |
2000 |
Internal loop/bulge and hairpin loop of the iron-responsive element of ferritin mRNA contribute to maximal iron regulatory protein 2 binding and translational regulation in the iso-iron-responsive element/iso-iron regulatory protein family. |
HL, IL/B, IRPs |
| 85 |
2000 |
Iron regulatory proteins in pathobiology. |
--- |
| 86 |
2000 |
Nitrogen monoxide activates iron regulatory protein 1 RNA-binding activity by two possible mechanisms: effect on the [4Fe-4S] cluster and iron mobilization from cells. |
DFO, IRP1, NO, SNAP, SNP, SPER-NO, UTR |
| 87 |
2000 |
Overexpression of the ferritin iron-responsive element decreases the labile iron pool and abolishes the regulation of iron absorption by intestinal epithelial (Caco-2) cells. |
IRPs |
| 88 |
2000 |
The cellular mechanisms of body iron homeostasis. |
IRPs |
| 89 |
2000 |
Thyrotropin-releasing hormone and epidermal growth factor regulate iron-regulatory protein binding in pituitary cells via protein kinase C-dependent and -independent signaling pathways. |
EGF, MAPK, PKC, TRH |
| 90 |
1999 |
Bacillus subtilis aconitase is an RNA-binding protein. |
--- |
| 91 |
1999 |
Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2. |
NO, SNP, TfR |
| 92 |
1999 |
Human cytoplasmic aconitase (Iron regulatory protein 1) is converted into its [3Fe-4S] form by hydrogen peroxide in vitro but is not activated for iron-responsive element binding. |
IRP1 |
| 93 |
1999 |
Identification of RNA-binding surfaces in iron regulatory protein-1. |
--- |
| 94 |
1999 |
Inactivation of both RNA binding and aconitase activities of iron regulatory protein-1 by quinone-induced oxidative stress. |
IRP-1, MSB |
| 95 |
1999 |
Increased placental iron regulatory protein-1 expression in diabetic pregnancies complicated by fetal iron deficiency. |
TfR |
| 96 |
1999 |
Iron-dependent regulation of transferrin receptor expression in Trypanosoma brucei. |
ESAG6, IRPs, TbACO, UTR |
| 97 |
1999 |
Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation. |
IRPs, TfR |
| 98 |
1999 |
Molecular cloning of mouse glycolate oxidase. High evolutionary conservation and presence of an iron-responsive element-like sequence in the mRNA. |
GOX, IRPs, UTR |
| 99 |
1999 |
Organization of the ferritin genes in Drosophila melanogaster. |
BDGP, HCH, IRP, LCH, MREs, PCR |
| 100 |
1999 |
Phylogenetic analysis of the 5-aminolevulinate synthase gene. |
ALS, HRMs |
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