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Abbreviation : IRF3
Long Form : interferon response factor 3
No. Year Title Co-occurring Abbreviation
2018 Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage. IAV, SAEC, TLR3
2017 Investigations on the molecular mode of action of the novel immunostimulator ZelNate: Activation of the cGAS-STING pathway in mammalian cells. BRD, cGAS, IFI16, STING, TLR9
2016 Non-Canonical Role of IKKalpha in the Regulation of STAT1 Phosphorylation in Antiviral Signaling. IFNs, IKKalpha, ISGs, NF-kappaB, RIG-I, STAT1
2015 HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity. HIV-1, IFN-beta, iNOS, STAT
2015 Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells. NF, PI3K, RV, TLR3
2014 HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1. IFN, IKKepsilon, RLRs, TRAF3
2014 Interferon response factor 3 is crucial to poly-I:C induced NK cell activity and control of B16 melanoma growth. INAM, KO
2014 Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells. CAR, IFN, ISGs, PRR, shRNA
2013 High mobility group Box 1 inhibits human pulmonary artery endothelial cell migration via a Toll-like receptor 4- and interferon response factor 3-dependent mechanism(s). HMGB1, HPAEC
10  2012 Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response. RT-qPCR, shRNA
11  2012 The linker of the interferon response factor 3 transcription factor is not unfolded. IFN-beta
12  2011 Cytoplasmic localized infected cell protein 0 (bICP0) encoded by bovine herpesvirus 1 inhibits beta interferon promoter activity and reduces IRF3 (interferon response factor 3) protein levels. BHV-1, IFN-beta
13  2011 FLIP (Flice-like inhibitory protein) suppresses cytoplasmic double-stranded-RNA-induced apoptosis and NF-kappaB and IRF3-mediated signaling. dsRNA, FADD, FLIP, IFN-beta, LPS, MDA5, MEFs, NF-kappaB, RIG-I, TLR4, TNFR
14  2011 Infection of cultured bovine cells with bovine herpesvirus 1 (BHV-1) or Sendai virus induces different beta interferon subtypes. BHV-1, BK, PRD III
15  2011 Pseudomonas aeruginosa suppresses interferon response to rhinovirus infection in cystic fibrosis but not in normal bronchial epithelial cells. CF, IFNs, MPA, ROS, RV
16  2011 Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide. CLIC, LPS
17  2010 Morphine disrupts interleukin-23 (IL-23)/IL-17-mediated pulmonary mucosal host defense against Streptococcus pneumoniae infection. IL-23, TCR delta
18  2010 Varicella-zoster virus immediate-early protein 62 blocks interferon regulatory factor 3 (IRF3) phosphorylation at key serine residues: a novel mechanism of IRF3 inhibition among herpesviruses. HELF, IE62, IFNs, ISGs, ISRE, VZV
19  2007 A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins. NF-kappaB, TLR4
20  2007 Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells. IP-10, ISG15, NF-kappaB, p.i, RIG-I, RSV, siRNA, STAT, TLR
21  2007 The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity. ---
22  2006 Regulation and function of IKK and IKK-related kinases. LPS, NAK, NF-kappaB, TFs, TNF-alpha
23  2004 Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response. ---
24  2001 Activation of interferon response factor-3 in human cells infected with herpes simplex virus type 1 or human cytomegalovirus. HCMV, HFL, HSV-1, ISGs