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Abbreviation : IRSp53
Long Form : insulin receptor substrate p53
No. Year Title Co-occurring Abbreviation
2017 Chronic methylphenidate regulates genes and proteins mediating neuroplasticity in the juvenile rat brain. ADHD, Arc, Arp2, Cdc42, MPH
2016 Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures. MIM, MTSS1, PIPs, WH2
2014 SH2B1 increases the numbers of IRSp53-induced filopodia. ---
2013 The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics. EBP50, PDZ
2012 Insulin receptor substrate protein 53kDa (IRSp53) is a negative regulator of myogenic differentiation. MIM
2012 LIN7 regulates the filopodium- and neurite-promoting activity of IRSp53. ---
2012 LIN7-IRSp53: A novel pathway for filopodia and neurite formation? mDia
2010 Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1). FRET, TIAM1
2010 WAVE2 targeting to phosphatidylinositol 3,4,5-triphosphate mediated by insulin receptor substrate p53 through a complex with WAVE2. IGF-I, IGF-IR, PI 3-kinase, siRNAs
10  2009 LIN7 mediates the recruitment of IRSp53 to tight junctions. IRSp53Delta5, LIN7, MDCK, TJ
11  2009 The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. KO, PSD
12  2008 Insulin receptor substrate protein 53 (IRSp53) as a binding partner of antimetastasis molecule NESH, a member of Abelson interactor protein family. ---
13  2008 Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2. Abi1, CSF-1, IRSp53DeltaSH3, RNAi, WASP
14  2005 NMDA receptor-dependent synaptic translocation of insulin receptor substrate p53 via protein kinase C signaling. PSD
15  2005 Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases. PSD, SH3
16  2005 WAVE/Scars in platelets. SH3, WASP
17  2004 Insulin receptor substrate of 53 kDa links postsynaptic shank to PSD-95. ---
18  2004 Standardized quantitative in situ hybridization using radioactive oligonucleotide probes for detecting relative levels of mRNA transcripts verified by real-time PCR. SQuISH
19  2003 MALS is a binding partner of IRSp53 at cell-cell contacts. ---
20  2003 Novel espin actin-bundling proteins are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53. PCs, PSD, SH3
21  2002 Novel isoform of insulin receptor substrate p53/p58 is generated by alternative splicing in the CRIB/SH3-binding region. ---
22  1999 [Cloning and characterization of cDNA for DRPLA interacting protein]. DRPLA