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Abbreviation : L-NAME
Long Form : NG-nitro-L-arginine methyl ester
No. Year Title Co-occurring Abbreviation
2020 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats. ACE, Ang II, AT1R, BP, sEH, TPPU
2020 A Novel Mechanism Underlying Multi-walled Carbon Nanotube-Triggered Tomato Lateral Root Formation: the Involvement of Nitric Oxide. EPR, LR, LSCM, MWCNTs, NO, NOS, NR
2020 A novel selective PPARalpha modulator, pemafibrate promotes ischemia-induced revascularization through the eNOS-dependent mechanisms. Ad-FGF21, eNOS, FGF, WT
2020 An Insight on the Role of Nitric Oxide in Yeast Apoptosis of Curcumin-Treated Candida albicans. NO, NOS
2020 Angiotensin converting enzyme inhibitor potentiates the hypoglycaemic effect of NG-nitro-L-arginine methyl ester (L-NAME) in rats. ACE, NO, NOS
2020 Anti-lipidemic Effect of Fractions of Peristrophe bivalvis Leaf in NG-nitro-L-arginine Methyl Ester (L-NAME) Treated Rats. HAF, HDF, HDL-C, HEF, HHF, LDL-C, NO, PB
2020 Anticonvulsant Activity of Essential Oil From Leaves of Zhumeria majdae (Rech.) in Mice: The Role of GABAA Neurotransmission and the Nitric Oxide Pathway. GABA, HLTEs, i.p, i.v, MES, NO, PTZ
2020 Antihypertensive effect of Phragmanthera incana (Schum) Balle on NG-nitro-L-Arginine methyl ester (L-NAME) induced hypertensive rats. GC-MS, IL-6, PILEE
2020 Antihypertensive potential of cis-[Ru(bpy)2(ImN)(NO)]3+, a ruthenium-based nitric oxide donor. HRV, ODQ
10  2020 Antihypertensive power of Naringenin is mediated via attenuation of mineralocorticoid receptor (MCR)/ angiotensin converting enzyme (ACE)/ kidney injury molecule (Kim-1) signaling pathway. ACE, MCR
11  2020 Antioxidant and vasorelaxant effects of aqueous extract of large cardamom in L-NAME induced hypertensive rats. AELC
12  2020 Aqueous extract of oakmoss produces antihypertensive activity in L-NAME-induced hypertensive rats through sGC-cGMP pathway. ---
13  2020 Astragaloside IV ameliorates preeclampsia-induced oxidative stress through Nrf2/HO-1 pathway in a rat model. HO-1, Nrf2, PE
14  2020 Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway. IL-1beta, NOS, TNF-alpha
15  2020 Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1alpha S-Nitrosylation and Transcriptional Activity in Hypoxia. BEC, Cav-1, HIF-1alpha, NOS
16  2020 Chronic aerobic exercise associated to low-dose L-NAME improves contractility without changing calcium handling in rat cardiomyocytes. EX, ExL, LV, NO, SBP
17  2020 Circ_0063517 acts as ceRNA, targeting the miR-31-5p-ETBR axis to regulate angiogenesis of vascular endothelial cells in preeclampsia. circRNAs, ETBR, PE, RIP
18  2020 Cobalt-Induced Hypercontraction is Mediated by Generationof Reactive Oxygen Species and Influx of Calcium in Isolated RatAorta. NO, PE, ROS, SOCC
19  2020 Comparative transcriptome combined with metabolome analyses revealed key factors involved in nitric oxide (NO)-regulated cadmium stress adaptation in tall fescue. Cd, cPTIO, NO, SNP
20  2020 Contribution of Baroreflex Afferent Pathway to NPY-Mediated Regulation of Blood Pressure in Rats. alpha-MSH, BP, HFD, NG, NPY, NTS, SHRs
21  2020 Crotonaldehyde-induced vascular relaxation and toxicity: Role of endothelium and transient receptor potential ankyrin-1 (TRPA1). AITC, CR, GC, PE, TRPA1
22  2020 Delta- and mu-opioid pathways are involved in the analgesic effect of Ocimum basilicum L in mice. BEO, GNTI, NAL, NO, NTD
23  2020 Disparate Effect of Antioxidant Supplements on the Basal Tone and Vascular Remodeling of the Aorta in Hypertensive Rats. MP, NO, SNP, Vit C
24  2020 Effect of Aqueous and Ethyl Acetate Fractions of Ziziphus jujuba Mill Extract on Cardiovascular Responses in Hypertensive Rats. HR, HTN, MAP, SBP, SNP, ZJ
25  2020 Effects of Agmatine on Contrast-Induced Nephropathy in Rats and Rabbits. CIN
26  2020 Effects of caffeine and caffeic acid on selected biochemical parameters in L-NAME-induced hypertensive rats. ACE, MDA, NOx
27  2020 Effects of Chaihu-Shugan-San on Small Intestinal Interstitial Cells of Cajal in Mice. CSS, GI, ICCs, ITR, NO, TRPV1
28  2020 Effects of NO/cGMP inhibitors in a rat model of anaphylactoid shock. GC, IC, MB, NO, SBP
29  2020 Effects of oxidative stress on liver, brain and spinal cord of rats using L-NAME and treated with hydroxyurea. A model of sickle cell complication. TBARS
30  2020 Endothelium-dependent vasodilatory effect of Smilax china Linn. water extract via PI3K/Akt signaling. PE, SCLWE
31  2020 Ephx2-gene deletion affects acetylcholine-induced relaxation in angiotensin-II infused mice: role of nitric oxide and CYP-epoxygenases. ACh
32  2020 Exogenous hydrogen sulfide alleviates surgery-induced neuroinflammatory cognitive impairment in adult mice by inhibiting NO signaling. IHC, IL-1beta, iNOS, MDA, MWM, NO, OFT, SOD, TNF-alpha, TUNEL, WB
33  2020 H2S induces NO in the regulation of AsA-GSH cycle in wheat seedlings by water stress. AOA, MDA, NO, SNP
34  2020 Hypotensive activity of Campomanesia xanthocarpa leaf extract: beyond angiotensin II type 1 receptor blockage. CXLE
35  2020 Increased endothelial nitric oxide production after low level lead exposure in rats involves activation of angiotensin II receptors and PI3K/Akt pathway. NO, PI3K
36  2020 Involvement of the nitric oxide signaling in modulation of naringin against intranasal manganese and intracerbroventricular beta-amyloid induced neurotoxicity in rats. AChE, AD, i.c.v
37  2020 Ivabradine Ameliorates Kidney Fibrosis in L-NAME-Induced Hypertension. HR, SBP
38  2020 Juglone as antihypertensive agent acts through multiple vascular mechanisms. CRCs, MAP
39  2020 l-arginine Supplementation Increased Only Endothelium-Dependent Relaxation in Sprague-Dawley Rats Fed a High-Salt Diet by Enhancing Abdominal Aorta Endothelial Nitric Oxide Synthase Gene Expression. eNOS
40  2020 Lipofundin MCT/LCT Inhibits Levcromakalim-Induced Vasodilation by Inhibiting Endothelial Nitric Oxide Release. ---
41  2020 Liposomal and Non-Liposomal Formulations of Vitamin C: Comparison of the Antihypertensive and Vascular Modifying Activity in Renovascular Hypertensive Rats. ACh, HR, HTN, NO, PE, SBP, Sham-veh, SNP
42  2020 Lobularia maritima (L.) Desv. Aerial Parts Methanolic Extract: In Vitro Screening of Biological Activity. DPPH, GC-MS, HPLC-DAD, HPLC-HRMS, LPS
43  2020 Macrophage neuronal nitric oxide synthase (NOS1) controls the inflammatory response and foam cell formation in atherosclerosis. NO, NOS1, oxLDLs, SR
44  2020 Melatonin attenuates hypertension and oxidative stress in a rat model of L-NAME-induced gestational hypertension. GD
45  2020 Naringin protects against Bisphenol-A induced oculopathy as implication of cataract in hypertensive rat model. NRG, PDE-51
46  2020 Naringin regulates erectile dysfunction by abolition of apoptosis and inflammation through NOS/cGMP/PKG signalling pathway on exposure to Bisphenol-A in hypertensive rat model. BPA, NRG, PDE-51
47  2020 Nicorandil, a KATP Channel Opener, Attenuates Ischemia-Reperfusion Injury in Isolated Rat Lungs. IR
48  2020 Nitric oxide effects on Rhodnius prolixus's immune responses, gut microbiota and Trypanosoma cruzi development. NO, NOS, RNS
49  2020 Nitric oxide plays a crucial role in midgut immunity under microsporidian infection in Antheraea pernyi. AMPs, NO, SNP
50  2020 Nitric oxide regulates the firing rate of neuronal subtypes in the guinea pig ventral cochlear nucleus. nNOS, NO, SNOG, VCN
51  2020 Nitric oxide synthase inhibitor L-NG-nitroarginine methyl ester (L-NAME) attenuates remobilization-induced joint inflammation. NO
52  2020 Nitric oxide synthase mediates cerebellar dysfunction in mice exposed to repetitive blast-induced mild traumatic brain injury. BBB, ICAM-1, NOS
53  2020 Nitric oxide, a communicator between tumor cells and endothelial cells, mediates the anti-tumor effects of Marsdenia Tenacissima Extract (MTE). ECs, eNOS, MTE, NO, NOS, NSCLC, PLMCs
54  2020 Nitric oxide-mediated inhibition of phenylephrine-induced contraction in response to hypothermia is partially modulated by endothelial Rho-kinase. eNOS, NO
55  2020 Novel Insights into the Mode of Action of Vasorelaxant Synthetic Polyoxygenated Chalcones. CVDs, ERalpha, ERalphaKO, NO, SAR, WT
56  2020 Oligodendrocytes Death Induced Sensorimotor and Cognitive Deficit in N-nitro-L-arginine methyl Rat Model of Pre-eclampsia. GD, PE, PND
57  2020 Pharmacological evaluation underlying the antinociceptive activity of two new hybrids NSAIDs tetrahydropyran derivatives. ---
58  2020 Possible Involvement of Nitric Oxide in the Antipruritic Effect of Metformin on Chloroquine-Induced Scratching in Mice. CQ, i.p, ID, nNOS, NO, NOS
59  2020 Preeclampsia as predisposing factor for hypertensive retinopathy: Participation by the RAAS and angiogenic factors. PE, PEDF, RAAS, VEGF
60  2020 Regulation of T Cell Function by Reactive Nitrogen and Oxygen Species in Collagen-Induced Arthritis. APCs, CII, RNS, ROS
61  2020 Retinoprotective Effect of Wild Olive (Acebuche) Oil-Enriched Diet against Ocular Oxidative Stress Induced by Arterial Hypertension. EVOO, NADPH, NOX
62  2020 Role of Arginase in Selective Impairment of Endothelium-Dependent Nitric Oxide Synthase-Mediated Dilation of Retinal Arterioles during Early Diabetes. COX, NOS
63  2020 Role of beta-Caryophyllene in the Antinociceptive and Anti-Inflammatory Effects of Tagetes lucida Cav. Essential Oil. TLEO
64  2020 Semi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities. HR, LVEDP, MAP
65  2020 Senecio serratuloides extract prevents the development of hypertension, oxidative stress and dyslipidemia in nitric oxide-deficient rats. ---
66  2020 Sex differences in progesterone-induced relaxation in the coronary bed from normotensive rats. CPP, NO
67  2020 Stimulation of the endogenous hydrogen sulfide synthesis suppresses oxidative-nitrosative stress and restores endothelial-dependent vasorelaxation in old rats. cNOS, iNOS, O-CMH, PLP
68  2020 Synchronous detection of vascular tension and nitric oxide release in pulmonary artery: A combined application of confocal wire myograph with confocal laser scanning microscopy. NO
69  2020 Tangeretin ameliorates erectile and testicular dysfunction in a rat model of hypertension. AT1R, eNOS, ICP, MAP, MDA, StAR
70  2020 The effect of swimming training on adrenomedullin levels, oxidative stress variables, and gastrocnemius muscle contractile properties in hypertensive rats. ADM, eNOS
71  2020 The effects of L-NAME on DU145 human prostate cancer cell line: A cytotoxicity-based study. IL-6, NO
72  2020 The investigation of antioxidant and anti-inflammatory potentials of apitherapeutic agents on heart tissues in nitric oxide synthase inhibited rats via Nomega-nitro-L-arginine methyl ester. ADMA, BP, CAPE, NF-kappaB, NOS, OSI, PON1, TAS, TOS
73  2020 The role of nitric oxide in small intestine differs between a single and a consecutive administration of methotrexate to rats. NO
74  2020 The skin blood flow response to exercise in boys and men and the role of nitric oxide. SkBF
75  2020 Urethral dysfunction and alterations of nitric oxide mechanisms in streptozotocin-induced diabetic rats with or without low-dose insulin treatment. DM, HFO, NC, NO, STZ, UPP
76  2020 Vasorelaxant and Antihypertensive Effects of Neferine in Rats: An In Vitro and In Vivo Study. eNOS, NO, SBP, sGC
77  2020 Virgin rice bran oil alleviates hypertension through the upregulation of eNOS and reduction of oxidative stress and inflammation in L-NAME-induced hypertensive rats. ACE, LIS, NO, VRBO
78  2019 7-Keto-Cholesterol and Cholestan-3beta, 5alpha, 6beta-Triol Induce Eryptosis through Distinct Pathways Leading to NADPH Oxidase and Nitric Oxide Synthase Activation. 7-KC, DPI, PI3K, RBC, RONS, ROS, TRIOL, XOR
79  2019 Ameliorative effects of pre-eclampsia by quercetin supplement to aspirin in a rat model induced by L-NAME. BW, GD, MDA, SBP
80  2019 Analytical methods to access the chemical composition of an Euphorbia tirucalli anticancer latex from traditional Brazilian medicine. AGS, FT-ICR MS, GC-MS, IL-6, NMR, NO, TNF-alpha
81  2019 Anti-diarrheal effect of Scutellaria baicalensis is associated with suppression of smooth muscle in the rat colon. GCs, S. baicalensis
82  2019 Antidiarrheal, vasorelaxant, and neuropharmacological actions of the diterpene tilifodiolide. GABA, TFD
83  2019 Antihypertensive activity of diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate: A continuation study in L-NAME treated wistar rats. TEA
84  2019 Antihypertensive Effect of Polyphenol-Rich Fraction of Azadirachta indica on Nomega-Nitro-L-Arginine Methyl Ester-Induced Hypertension and Cardiorenal Dysfunction. AI, KIM-1, NF-kB, Nrf2, PRF
85  2019 Antihypertensive effects of the hydro-ethanol extract of Senecio serratuloides DC in rats. HESS, NO
86  2019 Antihypertrophic Effects of Nebivolol on Neonatal Cardiomyocyte Hypertrophy Models. ---
87  2019 Aqueous Extract of Matricaria pubescens Exhibits Antihypertensive Activity in L-NAME-induced Hypertensive Rats through its Vasorelaxant Effect. AEMP, M. pubescens
88  2019 ASP6432, a type 1 lysophosphatidic acid receptor antagonist, reduces urethral function during urine voiding and improves voiding dysfunction. LPA, PVR, UPP, VE
89  2019 AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release. AT1R, GABA, MAP, NO, NTS
90  2019 Berberine restored nitrergic and adrenergic function in mesenteric and iliac arteries from streptozotocin-induced diabetic rats. BBR, EFS, NA, NO, TTX
91  2019 Blockade of NMDA Receptors and Nitric Oxide Synthesis Potentiated Morphine-Induced Anti-Allodynia via Attenuating Pain-Related Amygdala pCREB/CREB Signaling Pathway. CREB, NMDA, pCREB
92  2019 Bupivacaine-induced contraction is attenuated by endothelial nitric oxide release modulated by activation of both stimulatory and inhibitory phosphorylation (Ser1177 and Thr495) of endothelial nitric oxide synthase. BPV, eNOS, HUVECs
93  2019 Cardiovascular Effect of Diosgenin in Ovariectomized Rats. ---
94  2019 Carthamus Tinctorius L. extract attenuates cardiac remodeling in L-NAME-induced hypertensive rats by inhibiting the NADPH oxidase-mediated TGF-beta1 and MMP-9 pathway. LV, MDA, MMP-9, NOx, TGF-beta1
95  2019 Chronic inhibition of nitric oxide synthase modulates calcium handling in rat heart 1. ANP, NOS, PKA, TnI, VASP
96  2019 Chrysin Pretreatment Improves Angiotensin System, cGMP Concentration in L-NAME Induced Hypertensive Rats. Ang II, BP, BW, cGMP, NO
97  2019 Colonic Transit Disorder Mediated by Downregulation of Interstitial Cells of Cajal/Anoctamin-1 in Dextran Sodium Sulfate-induced Colitis Mice. ANO1, CMMCs, DSS, ICC, NPPB
98  2019 Contribution of potassium channels, beta2-adrenergic and histamine H1 receptors in the relaxant effect of baicalein on rat tracheal smooth muscle. ---
99  2019 Diuretic activity and neuropharmacological effects of an ethanol extract from Senna septemtrionalis (Viv.) H.S. Irwin & Barneby (Fabaceae). EPM, FST, OFT, PTZ, SSE, TST
100  2019 Effect of Artemisia Aucheri.L and Bupivacaine Encapsulated Nanoparticles on Nociceptive Pain. ---