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[Related PubMed/MEDLINE]
Total Number of Papers: 353
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| Abbreviation |
: LETO |
| Long Form |
: Long-Evans Tokushima Otsuka |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2022 |
Aerobic exercise training-induced follistatin-like 1 secretion in the skeletal muscle is related to arterial stiffness via arterial NO production in obese rats. |
cfPWV, eNOS, FSTL1, OLETF |
| 2 |
2022 |
Exercise training improves obesity-induced inflammatory signaling in rat brown adipose tissue. |
BAT, OLETF |
| 3 |
2022 |
Glucose Increases Hepatic Mitochondrial Antioxidant Enzyme Activities in Insulin Resistant Rats Following Chronic Angiotensin Receptor Blockade. |
4-HNE, ARE, AT1, GCLC, GPX1, IL-1beta, NAFLD, Nrf2, OLETF, SOD2 |
| 4 |
2022 |
Improved lipogenesis gene expression in liver is associated with elevated plasma angiotensin 1-7 after AT1 receptor blockade in insulin-resistant OLETF rats. |
Ang 1-7, Ang II, ARBs, AT1, FASN, FATP5, GCK, MetS, NAFLD, OLETF, TAG |
| 5 |
2022 |
Phosphodiesterase 5 inhibitor suppresses prostate weight increase in type 2 diabetic rats. |
bFGF, HIF-1alpha, IGF-1, IL, OLETF, PDE5i, T2D, TGF-beta, TNF-alpha |
| 6 |
2022 |
Simultaneous SGLT2 inhibition and caloric restriction improves insulin resistance and kidney function in OLETF rats. |
CR, IRI, OLETF, SGLT2i |
| 7 |
2021 |
Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway. |
HFrD, NAFLD, OLETF, UA |
| 8 |
2021 |
Chronic AT1 blockade improves hyperglycemia by decreasing adipocyte inflammation and decreasing hepatic PCK1 and G6PC1 expression in obese rats. |
AT1, GLUT4, IR, OLETF |
| 9 |
2021 |
Impact of Exercise and Detraining during Childhood on Brown Adipose Tissue Whitening in Obesity. |
BAT, OLETF, UCP1 |
| 10 |
2021 |
Liraglutide inhibits the progression of prediabetes in rats by reducing Raf-1 kinase inhibitor protein. |
ChAT, CON, FINS, H-DAR, HCNP, Ins1, LIRA, M3R, OLETF, PBO, qRT-PCR, RKIP, RPMI |
| 11 |
2021 |
Long-term light and moderate exercise intervention similarly prevent both hippocampal and glycemic dysfunction in presymptomatic type 2 diabetic rats. |
BDNF, MCT2, OLETF, T2DM |
| 12 |
2021 |
Mass recovery following caloric restriction reverses lipolysis and proteolysis, but not gluconeogenesis, in insulin resistant OLETF rats. |
CR, GC, IR, MS, OLETF, PR, TOF |
| 13 |
2021 |
Reductions in Intestinal Taurine-Conjugated Bile Acids and Short-Chain Fatty Acid-Producing Bacteria Might be Novel Mechanisms of Type 2 Diabetes Mellitus in Otsuka Long-Evans Tokushima Fatty Rats. |
GLP, OLETF, SCFAs, T-BAs, T2DM |
| 14 |
2021 |
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas. |
DM, ISO, OLETF, PI3K, SEVO, VSM |
| 15 |
2021 |
Subproteomic profiling from renal cortices in OLETF rats reveals mutations of multiple novel genes in diabetic nephropathy. |
DN, OLETF |
| 16 |
2020 |
Calorie restriction delays cardiac senescence and improves cardiac function in obese diabetic rats. |
AL, CR, HFD, OLETF |
| 17 |
2020 |
Correcting imbalance of sex hormones by a phosphodiesterase 5 inhibitor improves copulatory dysfunction in male rats with type 2 diabetes. |
LH, OLETF, PDE5I |
| 18 |
2020 |
Differential Contractile Reactivity to Nucleotides in Femoral Arteries of OLETF and LETO Rats. |
OLETF, UDP, UTP |
| 19 |
2020 |
Effect of the Sodium-Glucose Cotransporter 2 Inhibitor, Dapagliflozin, on Genitourinary Infection in an Animal Model of Type 2 Diabetes. |
IL-18, IL-1beta, OLETF |
| 20 |
2020 |
Exercise and Curcumin in Combination Improves Cognitive Function and Attenuates ER Stress in Diabetic Rats. |
ER, OLETF, T2DM |
| 21 |
2020 |
Hemodynamic response during hyperbaric treatment on skeletal muscle in a type 2 diabetes rat model. |
ATA, OLETF |
| 22 |
2020 |
Partial Body Mass Recovery After Caloric Restriction Abolishes Improved Glucose Tolerance in Obese, Insulin Resistant Rats. |
BM, CR, OGTT, OLETF, TG |
| 23 |
2020 |
Region-specific brain area reductions and increased cholecystokininpositive neurons in diabetic OLETF rats: implication for anxiety-like behavior. |
CCK, OLETF, PV |
| 24 |
2019 |
Canagliflozin, a sodium-glucose cotransporter2 inhibitor, normalizes renal susceptibility to type1 cardiorenal syndrome through reduction of renal oxidative stress in diabetic rats. |
MI, NOX, OLETF, SGLT2 |
| 25 |
2019 |
Effect of fosinopril on the renal cortex protein expression profile of Otsuka Long-Evans Tokushima Fatty rats. |
ACEIs, DN, FP, OLETF |
| 26 |
2019 |
Hyperbaric Normoxia Improved Glucose Metabolism and Decreased Inflammation in Obese Diabetic Rat. |
ATA, IL-10, OLETF, TNF-alpha |
| 27 |
2019 |
The effects of resistance training on bone mineral density and bone quality in type 2 diabetic rats. |
BMD, CON, OLETF, RT, T2DM |
| 28 |
2018 |
A Controlled Fermented Samjunghwan Herbal Formula Ameliorates Non-alcoholic Hepatosteatosis in HepG2 Cells and OLETF Rats. |
FSJH, HS, LBB, LBP, LCL, OLETF, PMM, SJH, VAT |
| 29 |
2018 |
Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats. |
ACR, ARB, HCC, HUVECs, IR, OLETF, PNL |
| 30 |
2018 |
Angiotensin receptor and tumor necrosis factor-alpha activation contributes to glucose intolerance independent of systolic blood pressure in obese rats. |
ARB, AT1, CCB, MetS, OLETF, SBP, TNF-alpha |
| 31 |
2018 |
Changes in lipid metabolism and capillary density of the skeletal muscle following low-intensity exercise training in a rat model of obesity with hyperinsulinemia. |
OLETF |
| 32 |
2018 |
Effect of sodium-glucose cotransporter 2 inhibitor, empagliflozin, and α-glucosidase inhibitor, voglibose, on hepatic steatosis in an animal model of type 2 diabetes. |
ACC, AMPK, FAS, FBP1, G6Pase, OLETF, PEPCK, SIRT1, SREBP-1c |
| 33 |
2018 |
Effects of voluntary running exercise on bone histology in type 2 diabetic rats. |
OLETF |
| 34 |
2018 |
Empagliflozin, an SGLT2 Inhibitor, Reduced the Mortality Rate after Acute Myocardial Infarction with Modification of Cardiac Metabolomes and Antioxidants in Diabetic Rats. |
beta-OHB, DM, MI, OLETF |
| 35 |
2018 |
Long-term insulin treatment leads to a change in myosin heavy chain fiber distribution in OLETF rat skeletal muscle. |
OLETF |
| 36 |
2018 |
Mild hyperbaric oxygen inhibits the growth-related decline in skeletal muscle oxidative capacity and prevents hyperglycemia in rats with type 2 diabetes mellitus. |
Myf5, MyoG, OLETF, PGC-1alpha, T2DM |
| 37 |
2018 |
miR-192 prevents renal tubulointerstitial fibrosis in diabetic nephropathy by targeting Egr1. |
DN, Egr-1, ESRD, FN, OLETF, qRT-PCR, TGF-beta1 |
| 38 |
2018 |
Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats. |
EMSA, FOXO1, HDACi, OLETF, T2DM |
| 39 |
2018 |
Simultaneous GLP-1 receptor activation and angiotensin receptor blockade increase natriuresis independent of altered arterial pressure in obese OLETF rats. |
AT1, GLP-1, MAP, OLETF |
| 40 |
2017 |
Alteration of Vascular Responsiveness to Uridine Adenosine Tetraphosphate in Aortas Isolated from Male Diabetic Otsuka Long-Evans Tokushima Fatty Rats: The Involvement of Prostanoids. |
NOS, OLETF, PG, TX |
| 41 |
2017 |
Angiotensin receptor blockade improves cardiac mitochondrial activity in response to an acute glucose load in obese insulin resistant rats. |
ARB, AT1, CAT, Nrf2, OLETF, RAS, SOD |
| 42 |
2017 |
Augmented Contractility to Noradrenaline in Femoral Arteries from the Otsuka Long-Evans Tokushima Fatty Rat, a Model of Type 2 Diabetes. |
COX, L-NNA, NOS, OLETF |
| 43 |
2017 |
Chronic saponin treatment attenuates damage to the pancreas in chronic alcohol-treated diabetic rats. |
LC, LE, LES, O-E, OC, OES, OLETF |
| 44 |
2017 |
Diabetes increases the susceptibility to acute kidney injury after myocardial infarction through augmented activation of renal Toll-like receptors in rats. |
AKI, DM, KIM-1, MI, MyD88, NGAL, OLETF, TLRs |
| 45 |
2017 |
Effects of early postnatal environment on hypothalamic gene expression in OLETF rats. |
DMH, NPY, OLETF, PND 23 |
| 46 |
2017 |
Impaired endothelium-derived hyperpolarization-type relaxation in superior mesenteric arteries isolated from female Otsuka Long-Evans Tokushima Fatty rats. |
EDH, OLETF |
| 47 |
2017 |
Long-term wheel-running can prevent deterioration of bone properties in diabetes mellitus model rats. |
OLETF |
| 48 |
2017 |
Obesity and type 2 diabetes, not a diet high in fat, sucrose, and cholesterol, negatively impacts bone outcomes in the hyperphagic Otsuka Long Evans Tokushima Fatty rat. |
BMC, HFSC, OLETF, T2D |
| 49 |
2017 |
Role of Glyceraldehyde-Derived AGEs and Mitochondria in Superoxide Production in Femoral Artery of OLETF Rat and Effects of Pravastatin. |
AGEs, ELISA, Glycer-AGEs, OLETF, PAD, TTFA |
| 50 |
2017 |
UDP-induced relaxation is enhanced in aorta from female obese Otsuka Long-Evans Tokushima Fatty rats. |
ACh, NO, OLETF, PE, UDP |
| 51 |
2016 |
Alterations of voltage-dependent K(+) channels in the mesenteric artery during the early and chronic phases of diabetes. |
4-AP, Kv, OLETF |
| 52 |
2016 |
Exogenous thyroxine improves glucose intolerance in insulin-resistant rats. |
AMPK, Di2, IR, IRI, Mct10, OGTT, OLETF, SIRT1, TH, UCP2 |
| 53 |
2016 |
Femoral bone structure in Otsuka Long-Evans Tokushima Fatty rats. |
OLETF, T2DM |
| 54 |
2016 |
Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry. |
OGTT, OLETF, PHGG |
| 55 |
2016 |
Increased Muscular 5alpha-Dihydrotestosterone in Response to Resistance Training Relates to Skeletal Muscle Mass and Glucose Metabolism in Type 2 Diabetic Rats. |
DHEA, DHT, GLUT4 |
| 56 |
2016 |
Investigation of Metabolism of Exogenous Glucose at the Early Stage and Onset of Diabetes Mellitus in Otsuka Long-Evans Tokushima Fatty Rats Using [1, 2, 3-13C]Glucose Breath Tests. |
AUC180, OLETF |
| 57 |
2016 |
Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats. |
HSC, IR, OLETF, SGLT2, TGF-beta |
| 58 |
2016 |
Maternal testosterone and reproductive outcome in a rat model of obesity. |
OLETF |
| 59 |
2016 |
Oral administration of green algae, Euglena gracilis, inhibits hyperglycemia in OLETF rats, a model of spontaneous type 2 diabetes. |
AUC, OGTT, OLETF |
| 60 |
2015 |
Activation of the NLRP3 inflammasome induces vascular dysfunction in obese OLETF rats. |
Drp1, eNOS, NLR, OLETF, OPA1 |
| 61 |
2015 |
Altered blood flow in cerebral perforating arteries of rat models of diabetes: A synchrotron radiation microangiographic study toward clinical evaluation of white matter hyperintensities. |
MCA, PA |
| 62 |
2015 |
Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts. |
CR, LETO-CR, OLETF, TL |
| 63 |
2015 |
Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. |
L-NAME, NAFLD, NO, OLETF |
| 64 |
2015 |
Diabetes and Age-Related Differences in Vascular Function of Renal Artery: Possible Involvement of Endoplasmic Reticulum Stress. |
ACh, COX, ER, OLETF, RA |
| 65 |
2015 |
Effect of high glucose levels on amyloid beta production in retinas of spontaneous diabetes mellitus Otsuka Long-Evans Tokushima fatty rats. |
NEP, OLETF |
| 66 |
2015 |
Endurance exercise training programs intestinal lipid metabolism in a rat model of obesity and type 2 diabetes. |
FAO, HIO, OLETF |
| 67 |
2015 |
Hyperuricemia-induced NLRP3 activation of macrophages contributes to the progression of diabetic nephropathy. |
NLRP3, OLETF |
| 68 |
2015 |
Rare sugar D-psicose prevents progression and development of diabetes in T2DM model Otsuka Long-Evans Tokushima Fatty rats. |
OLETF, T2DM |
| 69 |
2015 |
Voluntary Exercise Can Ameliorate Insulin Resistance by Reducing iNOS-Mediated S-Nitrosylation of Akt in the Liver in Obese Rats. |
iNOS, OLETF |
| 70 |
2014 |
Adipose gene expression profiles related to metabolic syndrome using microarray analyses in two different models. |
OLETF, PPARgamma |
| 71 |
2014 |
Adolescent rats are more prone to binge eating behavior: a study of age and obesity as risk factors. |
BE, BEP, OLETF |
| 72 |
2014 |
Aortic superoxide production at the early hyperglycemic stage in a rat type 2 diabetes model and the effects of pravastatin. |
cPKC, eNOS, OLETF, PI 3-kinase, PKC |
| 73 |
2014 |
Assessment of androgen replacement therapy for erectile function in rats with type 2 diabetes mellitus by examining nitric oxide-related and inflammatory factors. |
ART, ED, eNOS, ICP, IL-6, iNOS, MAP, NO, OLETF, SIRT1, T2DM, TNF-alpha |
| 74 |
2014 |
Beneficial paracrine effects of adipocytes from obese rats on cultured endothelial cells. |
LEA, LSA, OEA, OLETF, OSA |
| 75 |
2014 |
Carotid artery stenosis is exacerbated in spontaneously obese model rats with diabetes. |
OLETF |
| 76 |
2014 |
Combination of a peroxisome proliferator-activated receptor-gamma agonist and an angiotensinII receptor blocker attenuates myocardial fibrosis and dysfunction in type2 diabetic rats. |
ARB, OLETF, PPAR |
| 77 |
2014 |
Detailed localization of augmented angiotensinogen mRNA and protein in proximal tubule segments of diabetic kidneys in rats and humans. |
OLETF |
| 78 |
2014 |
Diabetes augments cognitive dysfunction in chronic cerebral hypoperfusion by increasing neuronal cell death: implication of cilostazol for diabetes mellitus-induced dementia. |
BCCAO, OLETF |
| 79 |
2014 |
Diesel exhaust particle-induced airway responses are augmented in obese rats. |
BAL, DEPs, OLETF |
| 80 |
2014 |
Downregulation of transient receptor potential M6 channels as a cause of hypermagnesiuric hypomagnesemia in obese type 2 diabetic rats. |
OLETF, TRP |
| 81 |
2014 |
Effects of acupuncture stimulation on blood glucose concentration in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat, an animal model for type-2 diabetes mellitus. |
AcOLETF, OLETF |
| 82 |
2014 |
Granulocyte-colony stimulating factor reduces cardiomyocyte apoptosis and ameliorates diastolic dysfunction in Otsuka Long-Evans Tokushima Fatty rats. |
G-CSF, G-CSFR, OLETF |
| 83 |
2014 |
Identification of genes whose expression is altered by obesity throughout the arterial tree. |
OLETF, RNA-Seq |
| 84 |
2014 |
Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats. |
eNOS, NAFLD, OLETF, T2D, TNF-alpha, VWR |
| 85 |
2014 |
Short-term caloric restriction does not reduce bone mineral density in rats with early type 2 diabetes. |
AL, BMD, CR, OLETF |
| 86 |
2014 |
Transcriptome-wide RNA sequencing analysis of rat skeletal muscle feed arteries. I. Impact of obesity. |
FDR, OLETF, RNA-Seq |
| 87 |
2014 |
Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats. |
KIM-1, OLETF |
| 88 |
2013 |
Aberrant activation of the intrarenal renin-angiotensin system in the developing kidneys of type 2 diabetic rats. |
ACE, AGT, Ang II, OLETF, PND, RAS |
| 89 |
2013 |
Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats. |
AT1, CS, NOX, OLETF, SDH |
| 90 |
2013 |
Changes in interleukin 18 in the retinas of Otsuka long-evans Tokushima fatty rats, a model of human type 2 diabetes. |
IFN-gamma, IL-18, OLETF |
| 91 |
2013 |
Chronic alcohol consumption, type 2 diabetes mellitus, insulin-like growth factor-I (IGF-I), and growth hormone (GH) in ethanol-treated diabetic rats. |
GH, IGF-I, IP-GTT, O-C, O-E, OLETF, T2DM |
| 92 |
2013 |
Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in feeding- and reward-related brain areas of young OLETF rats. |
CART, OLETF |
| 93 |
2013 |
COMP-angiopoietin-1 promotes cavernous angiogenesis in a type 2 diabetic rat model. |
COMP-Ang1, OLETF |
| 94 |
2013 |
Decreased perivascular CGRP-containing nerves in Otsuka Long-Evans Tokushima Fatty rats with insulin resistance and hypertension. |
CGRP, HOMA-IR, OLETF, PNS |
| 95 |
2013 |
Differential vasomotor effects of insulin on gastrocnemius and soleus feed arteries in the OLETF rat model: role of endothelin-1. |
ET, OLETF |
| 96 |
2013 |
Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats. |
FNDC5, OLETF |
| 97 |
2013 |
Epigallocatechin gallate attenuates ET-1-induced contraction in carotid artery from type 2 diabetic OLETF rat at chronic stage of disease. |
ACh, CA, EGCG, ET-1, OLETF, PE, SNP |
| 98 |
2013 |
Investigation of the metabolic effects of chronic clozapine treatment on CCK-1 receptor deficient Otsuka Long Evans Tokushima Fatty (OLETF) rats. |
HEGC, OLETF |
| 99 |
2013 |
Iron restriction prevents diabetic nephropathy in Otsuka Long-Evans Tokushima fatty rat. |
DM, OLETF |
| 100 |
2013 |
Neuroprotective effects of cilostazol on retinal ganglion cell damage in diabetic rats. |
GFAP, OLETF, RGC, TUNEL, VEGF |
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