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Abbreviation : LOX-1
Long Form : lectin-like oxidized LDL receptor-1
No. Year Title Co-occurring Abbreviation
2020 Aerobic Exercise Training Inhibits Neointimal Formation via Reduction of PCSK9 and LOX-1 in Atherosclerosis. BIC, BIE, LDL, PCSK9, SC, SD, VCAM-1
2020 Electronegative LDL Induces M1 Polarization of Human Macrophages Through a LOX-1-Dependent Pathway. LDL, nLDL
2020 Increased APOE glycosylation plays a key role in the atherogenicity of L5 low-density lipoprotein. APOE, LDL
2020 Increased Tissue Expression of Lectin-Like Oxidized LDL Receptor-1 (LOX-1) Is Associated with Disease Severity in Chronic Rhinosinusitis with Nasal Polyps. CRS, CT, LDL, ROS, SR-B1, SRs
2020 Inflammasome Activation in Human Macrophages Induced by a LDL (-) Mimetic Peptide. IL-18, IL-1beta, TLR4
2020 Interleukin-1beta Promotes Ox-LDL Uptake by Human Glomerular Mesangial Cells via LOX-1. Dil-Ox-LDL, HMCs, IL-1beta, oxLDL, PCR
2020 Interleukin-1beta Regulates Lipid Homeostasis in Human Glomerular Mesangial Cells. ABCA1, HMCs, IL-1beta, oxLDL
2020 LDL receptors, caveolae and cholesterol in endothelial dysfunction: oxLDLs accomplices or victims? Cav-1, oxLDLs
2020 LDL uptake-dependent phosphatidylethanolamine translocation to the cell surface promotes fusion of osteoclast-like cells. ABCG1, DKO, LDLR, OCLs, PE, sKO
10  2020 Natural flavone tricetin suppresses oxidized LDL-induced endothelial inflammation mediated by Egr-1. Egr-1, ICAM-1, IL-1beta, MCP-1, oxLDL, ROS, VCAM-1
11  2020 Oxidised Low-Density Lipoprotein and Its Receptor-Mediated Endothelial Dysfunction Are Associated with Coronary Artery Lesions in Kawasaki Disease. CALs, KD, oxLDL, PBMCs
12  2020 Role of Lectin-like Oxidized LDL Receptor-1 and Syncytiotrophoblast Extracellular Vesicles in the Vascular Reactivity of Mouse Uterine Arteries During Pregnancy. AT1, STBEVs
13  2020 Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 concentrations and prognosis of aneurysmal subarachnoid hemorrhage. oxLDL, SAH
14  2020 Systemic Amelioration via Curcumin in Rats following Splenectomy: Lipid Profile, Endothelial and Oxidative Damage. GPx, HDL, LDL, MDA, oxLDL, SC, SCO, SOD, TC, TG, VLDL
15  2019 Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease. alpha-SMA, IL-1beta, NAFLD, oxLDL
16  2019 Association between Negatively Charged Low-Density Lipoprotein L5 and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients. HC, LDL, RA
17  2019 Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. NTFs
18  2019 Fisetin, via CKIP-1/REGgamma, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells. CKIP-1, FC, OCT1, oxLDL, TC
19  2019 LOX-1 is involved in TLR2 induced RANKL regulation in peri-implantitis. PICF, RANKL, TLR2
20  2019 LOX-1+ PMN-MDSC enhances immune suppression which promotes glioblastoma multiforme progression. DCFDA, GBM, MDSC, PMN
21  2019 Paraoxonase 1: The Lectin-Like Oxidized LDL Receptor Type I and Oxidative Stress in the Blood of Men with Type II Obesity. CAT, GPx, MDA, PON1, SOD, TNF-alpha
22  2019 Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis. CYLD, ECs, FABP4, oxLDL, SR-A, SR-BI
23  2019 The DPP-4 inhibitor saxagliptin ameliorates ox-LDL-induced endothelial dysfunction by regulating AP-1 and NF-kappaB. AP-1, DPP-4, ICAM-1, IL-1beta, NF-kappaB, ox-LDL, VCAM-1
24  2019 Tofacitinib inhibits ox-LDL-induced adhesion of THP-1 monocytes to endothelial cells. HAECs, ICAM-1, IL-1beta, NF-kappaB, oxLDL, ROS, TNF-alpha, VCAM-1
25  2018 123I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice. DUR, oxLDL, TACs
26  2018 ATF4 Involvement in TLR4 and LOX-1-Induced Host Inflammatory Response to Aspergillus fumigatus Keratitis. A. fumigatus, ATF4, HCECs, JNK, TLR4
27  2018 Endoplasmic reticulum stress induced LOX-1+ CD15+ polymorphonuclear myeloid-derived suppressor cells in hepatocellular carcinoma. ER, HCC, sXBP1
28  2018 Fenretinide Inhibits Neutrophil Recruitment and IL-1beta Production in Aspergillus fumigatus Keratitis. IL-1beta, JNK, MPO, qRT-PCR
29  2018 Ginkgolide B ameliorates oxidized low-density lipoprotein-induced endothelial dysfunction via modulating Lectin-like ox-LDL-receptor-1 and NADPH oxidase 4 expression and inflammatory cascades. HUVECs, ICAM-1, MCP-1, NOX4, ox, VCAM-1
30  2018 Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo. hTERT, LDL, ROS
31  2018 Osteopontin is essential for IL-1beta production and apoptosis in peri-implantitis. ELISA, IL-1beta, OPN, PICF, rhOPN
32  2018 Oxidized low-density lipoprotein stimulates epithelial sodium channels in endothelial cells of mouse thoracic aorta. ENaC, oxLDL, sGC
33  2018 Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro. IL, IMQ, oxLDL, TNF
34  2018 Ulinastatin protects the lungs of COPD rats through the HMGB1/TLR4 signaling pathway. COPD, FEV, HMGB1, TLR4, TRAF-6
35  2018 Vitamin D3 Induces Gene Expression of Ox-LDL Scavenger Receptors in Streptozotocin-Induced Diabetic Rat Aortas: New Insight into the Role of Vitamin D in Diabetic Atherosclerosis. CD36, CD68, oxLDL, RT-PCR, SR-A, STZ
36  2017 Early Hippocampal i-LTP and LOX-1 Overexpression Induced by Anoxia: A Potential Role in Neurodegeneration in NPC Mouse Model. i-LTP, LDL, NPCD, OGD, WT
37  2017 Electronegative L5-LDL induces the production of G-CSF and GM-CSF in human macrophages through LOX-1 involving NF-kappaB and ERK2 activation. AMI, ERK, G-CSF, GM-CSF, LDL, NF
38  2017 Electronegative Low-Density Lipoprotein L5 Impairs Viability and NGF-Induced Neuronal Differentiation of PC12 Cells via LOX-1. AD, LDL, NGF
39  2017 Electronegative Low-Density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated With Metabolic Syndrome. LDL, MetS
40  2017 Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL. CpG, MAMP, OLR1, TLR9
41  2017 Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways. ACS, LOX-1TG, Oct-1, oxLDL, SIRT1, TF
42  2017 Expression of LOX-1 in human mesangial cells is increased by Ox-LDL and IL-1beta treatment. HMCs, IL-1beta, oxLDL
43  2017 Hyperoside inhibits the effects induced by oxidized low-density lipoprotein in vascular smooth muscle cells via oxLDL-LOX-1-ERK pathway. ERK, oxLDL, VSMCs
44  2017 LOX-1 is involved in IL-1beta production and extracellular matrix breakdown in dental peri-implantitis. ELISA, IL-1beta, MMP2, MMP9, PICF, RT-PCR
45  2017 Mechanisms of foam cell formation in atherosclerosis. LAL, LDL, NCEH, SR, VSMCs
46  2017 Quercetin Inhibits LPS-Induced Inflammation and ox-LDL-Induced Lipid Deposition. AS, COX-2, IL, LPS, MCP-1, MMP-1, oxLDL, QCT, SOCS3
47  2016 Collectin CL-P1 utilizes C-reactive protein for complement activation. CFH, CL-P1, CRP, SR, TCC
48  2016 Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-Deficient Mice: Role of NOX4/NF-kappaB Mediated Lectin-Like Oxidized LDL Receptor-1 (LOX-1) of the Endothelium. DHT, HUVECs, LPS, NOX4, ROS
49  2016 Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies. ESM-1, GDF15, HGF, IL27-A, MMP-1, MMP-10, MMP-12, TRAIL-R2, uPAR
50  2016 Effects of Porphyromonas gingivalis lipopolysaccharide on the expression of key genes involved in cholesterol metabolism in macrophages. ABCG1, ACAT1, LDL, Pg-LPS
51  2016 Ginkgo biloba extract inhibits oxidized low-density lipoprotein (oxLDL)-induced matrix metalloproteinase activation by the modulation of the lectin-like oxLDL receptor 1-regulated signaling pathway in human umbilical vein endothelial cells. ERK, GBE, MMPs, oxLDL, PKC, PPARgamma
52  2016 High Glucose Enhances oxLDL-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells Largely via Inducing Lectin-Like ox-LDL Receptor-1. DN, HRPTEpCs, MAPK
53  2016 Interplay between CRP, Atherogenic LDL, and LOX-1 and Its Potential Role in the Pathogenesis of Atherosclerosis. B-face, CRP, oxLDL
54  2016 Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients. ER, LDL, PMN-MDSC
55  2016 Macrophage-mediated cholesterol handling in atherosclerosis. ABC, ACAT1, ER, LAL, oxLDL, SR
56  2016 Membrane-bound heat shock proteins facilitate the uptake of dying cells and cross-presentation of cellular antigen. HSPs
57  2016 Pinoresinol Diglucoside Alleviates oxLDL-Induced Dysfunction in Human Umbilical Vein Endothelial Cells. ICAM-1, MDA, NF-kappaB, NO, oxLDL, PCR, PD, ROS, SOD
58  2016 Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation. IKK2, LDL, NF-kappaB
59  2016 Prothrombotic lipoprotein patterns in stroke. LDLs
60  2016 Suppression of EC-SOD by oxLDL During Vascular Smooth Muscle Cell Proliferation. EC-SOD, ERK, MEK, oxLDL, ROS, VSMCs
61  2016 Terminalia bellirica Extract Inhibits Low-Density Lipoprotein Oxidation and Macrophage Inflammatory Response in Vitro. DPPH, IL-1beta, LDL, MMP, ROS, TBE, TNF-alpha
62  2016 The lectin-like oxidized LDL receptor-1: a new potential molecular target in colorectal cancer. CRC
63  2015 Cross-talk between LOX-1 and PCSK9 in vascular tissues. KO, LPS, mtROS, PCSK9, WT
64  2015 Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: role of lectin-like oxidized LDL receptor-1 (LOX-1). CTS, Nox4, oxLDL, ROS
65  2015 Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction. CKD, LDL, NO
66  2015 Lectin-like ox-LDL receptor-1 (LOX-1)-Toll-like receptor 4 (TLR4) interaction and autophagy in CATH.a differentiated cells exposed to angiotensin II. Ang II, MAPK, oxLDL, siRNA, TLRs, TRIF
67  2015 Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state. LDL, RANKL
68  2015 Lipopolysaccharide augments the uptake of oxidized LDL by up-regulating lectin-like oxidized LDL receptor-1 in macrophages. oxLDL
69  2015 LOX-1 in atherosclerotic disease. LAB, LDL, LDLC, sLOX-1
70  2015 LOX-1 in macrophage migration in response to ox-LDL and the involvement of calpains. oxLDL
71  2015 Sesamol reduces the atherogenicity of electronegative L5 LDL in vivo and in vitro. EC, HFD, LDL
72  2015 The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population. ELISA, PE, sLOX-1, SNPs
73  2015 The Relationship between Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Ligands Containing Apolipoprotein B and the Cardio-Ankle Vascular Index in Healthy Community Inhabitants: The KOBE Study. CAVI, CVD, LAB, LDL, sLOX-1
74  2014 Carbamylated low-density lipoprotein induces endothelial dysfunction. CKD, cLDL, eNOS, LDL, nLDL, NO, ROS
75  2014 Combination therapy of amlodipine and atorvastatin has more beneficial vascular effects than monotherapy in salt-sensitive hypertension. AML, AT, CRP, DS, EDR, eNOS, MCP-1, SBP
76  2014 Endothelial overexpression of LOX-1 increases plaque formation and promotes atherosclerosis in vivo. HCD, LOX-1TG, oxLDL, WT
77  2014 Homocysteine induces blood vessel global hypomethylation mediated by LOX-1. ECs, Hcy, HHcy, HLP, nMS-PCR, SAH, SAM
78  2014 Ox-LDL induces endothelial cell apoptosis via the LOX-1-dependent endoplasmic reticulum stress pathway. ER, oxLDL
79  2014 OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators. ECs, oxLDL
80  2014 Potential pathological roles for oxidized low-density lipoprotein and scavenger receptors SR-AI, CD36, and LOX-1 in aortic valve stenosis. AVS, oxLDL, SR-A1, SR-B1
81  2014 Resveratrol and desferoxamine protect human OxLDL-treated granulosa cell subtypes from degeneration. CD36, DFO, GCs, oxLDL, RES, TLR4
82  2014 Role of lectin-like oxidized low density lipoprotein-1 in fetoplacental vascular dysfunction in preeclampsia. NO, PE, ROS
83  2014 Role of oxidized LDL and lectin-like oxidized LDL receptor-1 in cerebral vasospasm after subarachnoid hemorrhage. eNOS, oxLDL, SAH
84  2013 ATP-binding cassette transporter A1 expression is decreased in preeclamptic placentas. ABCA1, LXRs, oxLDL
85  2013 Chlamydia pneumoniae induces expression of pro-atherogenic factors through activation of the lectin-like oxidized LDL receptor-1. oxLDL
86  2013 Effects of Oral L-Citrulline Supplementation on Lipoprotein Oxidation and Endothelial Dysfunction in Humans with Vasospastic Angina. ADMA, eNOS, FMD, LAB, NO
87  2013 Electronegative low-density lipoprotein increases C-reactive protein expression in vascular endothelial cells through the LOX-1 receptor. CRP, ECs, HAECs, LDL, LDL-C, ROS
88  2013 HDL cholesterol in cardiovascular diseases: the good, the bad, and the ugly? CAD, CETP, CKD, NO, TLR2
89  2013 Human endothelial lecitin-like oxLDL receptor-1 (LOX-1) expression is not associated with impairment of endothelium-dependent vasoreactivity in conduit vessels. EDVR, eNOS, FMD, HUVEC, LDL, TNF-alpha
90  2013 Inhibition of lectin-like oxidized low-density lipoprotein-1 receptor protects against plasma-mediated vascular dysfunction associated with pre-eclampsia. BK, ELISA, LDL, NP, oxLDL, PE, sLOX-1, SNP
91  2013 Lectin-like oxidised LDL receptor-1 as a marker of endothelial dysfunction in Behcet's disease. eNOS, ET-1, NO, oxLDL, SLE
92  2013 LOX-1: a male hormone-regulated scavenger receptor for atherosclerosis. oxLDL
93  2013 ox-LDL downregulates eNOS activity via LOX-1-mediated endoplasmic reticulum stress. BAECs, BFA, eNOS, ER, GRP, oxLDL, PBA, PERK
94  2013 Oxidized LDL and LOX-1 in experimental sepsis. oxLDL
95  2013 The essential role of p38 MAPK in mediating the interplay of oxLDL and IL-10 in regulating endothelial cell apoptosis. HUVEC, IL-10, JNK, MAPK, oxLDL, SOCS3
96  2013 The lectin-like oxidized low-density lipoprotein receptor-1 as therapeutic target for atherosclerosis, inflammatory conditions and longevity. ---
97  2012 Current Concepts of the Role of Oxidized LDL Receptors in Atherosclerosis. oxLDL
98  2012 Decreased lectin-like oxidized LDL receptor 1 (LOX-1) and low Nrf2 activation in placenta are involved in preeclampsia. HO-1, Nrf2, oxLDL
99  2012 Degradation of heparan sulfate proteoglycans enhances oxidized-LDL-mediated autophagy and apoptosis in human endothelial cells. Hep III, HSPG, HUVECs, oxLDL, ROS
100  2012 Effect of advanced glycation end products on lectin-like oxidized low density lipoprotein receptor-1 expression in endothelial cells. AGEs, mTOR, PI3K, RICTOR