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Abbreviation : LOX-1
Long Form : lectin-like oxidized low-density lipoprotein receptor-1
No. Year Title Co-occurring Abbreviation
2020 A modified laser-induced choroidal neovascularization animal model with intravitreal oxidized low-density lipoprotein. CCR2, CNV, IL-6, LDL, MMP9, oxLDL, PBS, qRT-PCR, RPE, VEGF, WB
2020 Apremilast ameliorates ox-LDL-induced endothelial dysfunction mediated by KLF6. HAECs, IL-6, IL-8, JNK, KLF6, MCP-1, oxLDL, PDE4, TNF-alpha, VCAM-1
2020 Association between impaired cutaneous microvascular endothelial function and lectin-like oxidized low-density lipoprotein receptor-1 in patients with coronary slow flow. CSF, sLOX-1, TFC
2020 Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis. CCTA, IQR, NCB, PASI, sLOX-1
2020 Baicalein exerts neuroprotective effect against ischaemic/reperfusion injury via alteration of NF-kB and LOX and AMPK/Nrf2 pathway. COX-2, I/R, NF-kB, PGE2
2020 Biomimetic 3D Models for Investigating the Role of Monocytes and Macrophages in Atherosclerosis. ECM, oxLDL
2020 Decidua-derived granulocyte macrophage colony-stimulating factor induces polymorphonuclear myeloid-derived suppressor cells from circulating CD15+ neutrophils. DES, EES, GM-CSF, MDSC, PD-1, PMN-MDSCs
2020 Donepezil Prevents ox-LDL-Induced Attachment of THP-1 Monocytes to Human Aortic Endothelial Cells (HAECs). Egr-1, HAECs, ICAM-1, IL-6, oxLDL, TF, TNF-alpha
2020 ERK1/2-PPARgamma pathway is involved in Chlamydia pneumonia-induced human umbilical vein endothelial cell apoptosis through increased LOX-1 expression. Cpn, HUVECs, PPARgamma
10  2020 Evaluation of subclinical atherosclerosis in Turkish patients with acne vulgaris receiving systemic isotretinoin. oxLDL
11  2020 Gynura procumbens ethanol extract and its fractions inhibit macrophage derived foam cell formation. ABCA1, ELISA, RT-qPCR
12  2020 Human cytomegalovirus infection is correlated with atherosclerotic plaque vulnerability in carotid artery. CMV, MMP-9, TNF-alpha
13  2020 Inhibition of LOX-1 prevents inflammation and photoreceptor cell death in retinal degeneration. LD, polyI
14  2020 LNCRNA OIP5-AS1 regulates oxidative low-density lipoprotein-mediated endothelial cell injury via miR-320a/LOX1 axis. AS, CCK-8, ECs, LDH, miR-320a, oxLDL, qRT-PCR
15  2020 LOX-1 (Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) Deletion Has Protective Effects on Stroke in the Genetic Background of Stroke-Prone Spontaneously Hypertensive Rat. SHRSP
16  2020 LOX-1 Regulates P. gingivalis-Induced Monocyte Migration and Adhesion to Human Umbilical Vein Endothelial Cells. CAMs, CCR2, HUVECs, ICAM-1, MCP-1, NF-kappaB, P. gingivalis
17  2020 N-3 PUFAs inhibited hepatic ER stress induced by feeding of a high-saturated fat diet accompanied by the expression LOX-1. ER, HFD, NAFLD, PUFAs
18  2020 Nerolidol inhibits the LOX-1 / IL-1beta signaling to protect against the Aspergillus fumigatus keratitis inflammation damage to the cornea. A. fumigatus, HCECs, IL-1beta, MIC, MPO, PBS, qRT-PCR
19  2020 Oleacein and Foam Cell Formation in Human Monocyte-Derived Macrophages: A Potential Strategy Against Early and Advanced Atherosclerotic Lesions. ACAT1, GM-CSF, oxLDL, RT-PCR, SR-A1, WB
20  2020 Oxidized low-density lipoproteins induce tissue factor expression in T-lymphocytes via activation of lectin-like oxidized low-density lipoprotein receptor-1. oxLDLs, ROS, TF
21  2020 Sarpogrelate and rosuvastatin synergistically ameliorate aortic damage induced by hyperlipidemia in apolipoprotein E-deficient mice. HFD, IL, LDL
22  2020 Serum LOX-1 is a novel prognostic biomarker of colorectal cancer. ---
23  2020 Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 as a biomarker of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. aSAH, DCI, sLOX-1, WFNS
24  2020 Stratification by Multidimensional Approach for Rational Treatment of Asymptomatic Carotid Stenosis (SMART-K Study): Study Protocol. ACS, CS, IPH, MRI
25  2019 A Secreted Phospholipase A2 Induces Formation of Smooth Muscle Foam Cells Which Transdifferentiate to Macrophage-Like State. ACAT, AcLDL, DGAT, GIIA sPLA2s, LDs, MT-III, PPARs, SR-A1, VSMCs
26  2019 Apolipoprotein E Deficiency Causes Endothelial Dysfunction in the Mouse Retina. ---
27  2019 C-terminus of heat shock protein 60 can activate macrophages by lectin-like oxidized low-density lipoprotein receptor 1. APCs, HSP60C, MAPK, MyD88, OVA, TLR
28  2019 Celastrol ameliorates Aspergillus fumigatus keratitis via inhibiting LOX-1. A. fumigatus, CLT
29  2019 CRP and LOX-1: a Mechanism for Increasing the Tumorigenic Potential of Colorectal Cancer Carcinoma Cell Line. CRC, CRP, oxLDL
30  2019 Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury. eLOX-1TG, I/R, siRNA, tMCAO, WT
31  2019 Depletion of CPEB1 protects against oxidized LDL-induced endothelial apoptosis and inflammation though SIRT1/LOX-1 signalling pathway. AS, Co-IP, CPEB1, JNK, oxLDL, siRNA, SIRT1
32  2019 Design and Development of Novel 1,3,5-Triazine-Procaine Derivatives as Protective Agent against Myocardial Ischemia/Reperfusion Injury via Inhibitor of Nuclear Factor-kappaB. Bax, Bcl-2, CAT, CF, GPx, HR, I/R, LPS, LVDP, NF-kappaB, SOD, TBARS
33  2019 Design and Synthesis of PEG-Oligoglycerol Sulfates as Multivalent Inhibitors for the Scavenger Receptor LOX-1. oxLDL, PEG
34  2019 Emerging Biomarkers of Oxidative Stress in Acute and Stable Coronary Artery Disease: Levels and Determinants. ACS, AMI, CAD, CV, OS, ROM
35  2019 Exosomal miRNA Let-7 from Menstrual Blood-Derived Endometrial Stem Cells Alleviates Pulmonary Fibrosis through Regulating Mitochondrial DNA Damage. IPF, MenSCs, mtDNA, NTA, ROS, TEM
36  2019 Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse cardiovascular events: A multicentre pilot study. ACS, CAD, ELISA, MACE, sLOX-1
37  2019 Inhibition of LOX-1 alleviates the proinflammatory effects of high-mobility group box 1 in Aspergillus fumigatus keratitis. A. fumigatus, HMGB1, IL-1beta, MIP-2, PBS, TNF-alpha
38  2019 Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage. ICH
39  2019 Lipoprotein Receptor Signaling in Atherosclerosis. ApoER2, CD36, LDLR, LRP, SR-BI, VLDLR
40  2019 LOX-1 and atherosclerotic-related diseases. ACS, CAD, oxLDL
41  2019 LOX-1, the Common Therapeutic Target in Hypercholesterolemia: A New Perspective of Antiatherosclerotic Action of Aegeline. AG, AV, HCD, oxLDL
42  2019 LOX-1: Its cytotopographical variance and disease stress. oxLDL
43  2019 Microglial LOX-1/MAPKs/NF-kappaB positive loop promotes the vicious cycle of neuroinflammation and neural injury. CNS
44  2019 Naringin Reverses High-Cholesterol Diet-Induced Vascular Dysfunction and Oxidative Stress in Rats via Regulating LOX-1 and NADPH Oxidase Subunit Expression. 4-HNE, ACh, DHE, iNOS, NADPH, NO
45  2019 OxHDL controls LOX-1 expression and plasma membrane localization through a mechanism dependent on NOX/ROS/NF-kappaB pathway on endothelial cells. oxHDL
46  2019 Peroxisome Proliferator-Activated Receptor-gamma Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p. HUVECs, TZD
47  2019 Pro-oncogenic action of LOX-1 and its splice variant LOX-1Delta4 in breast cancer phenotypes. ---
48  2019 Requisite roles of LOX-1, JNK, and arginase in diabetes-induced endothelial vasodilator dysfunction of porcine coronary arterioles. NO
49  2019 Serum Levels of Carbamylated LDL and Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated with Coronary Artery Disease in Patients with Metabolic Syndrome. AUC, CAD, CI, cLDL, HDL, MetS, OR, ROC, sLOX-1
50  2019 Serum Levels of Carbamylated LDL, Nitrotyrosine and Soluble Lectin-like Oxidized Low-density Lipoprotein Receptor-1 in Poorly Controlled Type 2 Diabetes Mellitus. cLDL, NT, sLOX-1, T2DM
51  2019 The association between local arteriosclerosis of the prostatic arteries and chronic inflammation in human benign prostatic enlargement. BPE, IBA1, RARP
52  2019 Upregulated LOX-1 Receptor: Key Player of the Pathogenesis of Atherosclerosis. oxLDL
53  2019 [Effect and mechanism of PCSK9 on lectin-like oxidized low-density lipoprotein receptor-1 mediated oxidized low-density lipoprotein uptake by THP-1 derived macrophages]. COX-2, NADPH, NF-kappaB, oxLDL, ROS, TLR4
54  2019 [Gly14]-Humanin Prevents Lipid Deposition and Endothelial Cell Apoptosis in a Lectin-like Oxidized Low-density Lipoprotein Receptor-1-Dependent Manner. HN, HUVEC, oxLDL
55  2018 Alterations in vascular function by syncytiotrophoblast extracellular vesicles via lectin-like oxidized low-density lipoprotein receptor-1 in mouse uterine arteries. AT1, AT2, GD, HUVECs, LOX-1-KO, MCh, NO, STBEVs
56  2018 Cinnamaldehyde protects VSMCs against ox-LDL-induced proliferation and migration through S arrest and inhibition of p38, JNK/MAPKs and NF-kappaB. CIN, HO-1, MCP-1, MMP-2, VSMCs
57  2018 Clinical analysis of lectin-like oxidized low-density lipoprotein receptor-1 in patients with in-stent restenosis after percutaneous coronary intervention. AUC, CAG, CREA, HDL-C, ISR, PCI, ROC, UA
58  2018 Ecrg4 peptide is the ligand of multiple scavenger receptors. ECRG4, TLRs
59  2018 Enhanced Bioactivity of the Anti-LOX-1 scFv Engineered by Multimerization Strategy. scFv
60  2018 Expression of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Human Epicardial and Intramyocardial Coronary Arteries of Male Patients Undergoing Coronary Artery Bypass Grafting. ---
61  2018 Fluid shear stress regulates the expression of Lectin-like oxidized low density lipoprotein receptor-1 via KLF2-AP-1 pathway depending on its intensity and pattern in endothelial cells. AP-1, ECs, FSS, KLF2, LSS, OSS
62  2018 LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension. PASMCs, PH
63  2018 LOX-1 receptor: A potential link in atherosclerosis and cancer. oxLDL, ROS
64  2018 Polyphenols from Ilex latifolia Thunb. (a Chinese bitter tea) exert anti-atherosclerotic activity through suppressing NF-kappaB activation and phosphorylation of ERK1/2 in macrophages. CD36, IL, iNOS, LC-MS, oxLDL
65  2018 Protective Effects of Chinese Traditional Medicine Longhu Rendan against Atherosclerosis via Negative Regulation of LOX-1. LDL-C, LHRD, TC, TG
66  2018 Role of vasoactive intestinal peptide in Aspergillus fumigatus-infected cornea. A. fumigatus, ELISA, IL-1beta, MPO, p.i, PCR, TLR4, TNF-alpha, VIP
67  2018 Thymoquinone reduces cardiac damage caused by hypercholesterolemia in apolipoprotein E-deficient mice. hs-CRP, LDL-C, TC
68  2018 Toll-like receptor 2 activation primes and upregulates osteoclastogenesis via lox-1. BMCs, BMMs, FACS, LPS, MAPK, MyD88, OCs, oxLDL, PCR, RANKL, TLR, TRAP
69  2017 Association of angiotensin II receptor 1 and lectin-like oxidized low-density lipoprotein receptor-1 mediates the cardiac hypertrophyinduced by oxidized low-density lipoprotein. oxLDL
70  2017 Contribution of lectin-like oxidized low-density lipoprotein receptor-1 and LOX-1 modulating compounds to vascular diseases. oxLDL
71  2017 Expression and Characterization of a Single-Chain Variable Fragment against Human LOX-1 in Escherichia coli and Brevibacillus choshinensis. B. choshinensis, E. coli, scFv
72  2017 Free Fatty Acids Induce Autophagy and LOX-1 Upregulation in Cultured Aortic Vascular Smooth Muscle Cells. FFAs, OA, PA, VSMCs
73  2017 Involvement of epithelial-mesenchymal transition afforded by activation of LOX-1/ TGF-beta1/KLF6 signaling pathway in diabetic pulmonary fibrosis. EMT, HBECs, HE, KLF6, STZ, TGF-beta1
74  2017 Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial-mesenchymal transition and PI3K/Akt/GSK3beta activation. GC
75  2017 Lectin-like oxidized low-density lipoprotein receptor-1 promotes endothelial dysfunction in LDL receptor knockout background. CD, WD, WT
76  2017 LOX-1 in Atherosclerosis and MyocardialIschemia: Biology, Genetics, and Modulation. ox-LDL
77  2017 LOX-1 promotes right ventricular hypertrophy in hypoxia-exposed rats. ANP, BNP, NOX, ROS, RVH
78  2017 MicroRNA-98 rescues proliferation and alleviates ox-LDL-induced apoptosis in HUVECs by targeting LOX-1. ECs, HUVECs, miR-98, miRNAs, oxLDL
79  2017 Porphyromonas gingivalis Infection Accelerates Atherosclerosis Mediated by Oxidative Stress and Inflammatory Responses in ApoE-/- Mice. APOE, CRP, FAS, iNOS, NF-kappaB, NOX, oxLDL, P. gingivalis, ROS, VLDL
80  2017 Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation. IVDD, IVDs, MMP3, NP, NPCs, oxLDL
81  2017 Syncytiotrophoblast extracellular vesicles impair rat uterine vascular function via the lectin-like oxidized LDL receptor-1. STBEVs
82  2017 The Dipeptidyl Peptidase-4 Inhibitor Teneligliptin Reduces Aortic Damage from Hypercholesterolaemia in Apolipoprotein E-Deficient Mice. ---
83  2017 The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARgamma. ELISAs, oxLDL
84  2016 Coronary Microembolization Induces Cardiomyocyte Apoptosis in Swine by Activating the LOX-1-Dependent Mitochondrial Pathway and Caspase-8-Dependent Pathway. CME, siRNA
85  2016 Efficacy of Oral Curcuminoid Fraction from Curcuma xanthorrhiza and Curcuminoid Cider in High-cholesterol Fed Rats. CD44, HCD, ICAM-1, iNOS, PCR
86  2016 Ghrelin inhibits oxLDL-induced inflammation in RAW264.7 mouse macrophages through down-regulation of LOX-1 expression via NF-kappaB signaling pathway. IL, oxLDL, TNF
87  2016 High Levels of Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Acute Stroke: An Age- and Sex-Matched Cross-Sectional Study. CI, ICH, OR, sLOX-1
88  2016 Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces cardiac fibroblast proliferation by suppressing GATA Binding Protein 4. CFs, GATA4
89  2016 LOX-1-Mediated Effects on Vascular Cells in Atherosclerosis. ECs, oxLDL, VSMCs
90  2016 Osteopontin deficiency reduces kidney damage from hypercholesterolemia in Apolipoprotein E-deficient mice. CKD, HD, ND, OPN, PAS, rmOPN
91  2016 Overexpression of LOXIN Protects Endothelial Progenitor Cells From Apoptosis Induced by Oxidized Low Density Lipoprotein. hEPC, oxLDL
92  2016 Physiology and pathophysiology of oxLDL uptake by vascular wall cells in atherosclerosis. CV, oxLDL, SRs, TLRs
93  2016 Rapamycin Inhibits Oxidized Low Density Lipoprotein Uptake in Human Umbilical Vein Endothelial Cells via mTOR/NF-kappaB/LOX-1 Pathway. HUVECs, mTOR, oxLDL
94  2016 Roles of LOX-1 in microvascular dysfunction. ---
95  2016 The human rs1050286 polymorphism alters LOX-1 expression through modifying miR-24 binding. A/G, AMI, CAD, SNP
96  2016 The relationship between serum lectin-like oxidized LDL receptor-1 levels and systolic heart failure. EF
97  2015 1,25-dihydroxyvitamin D3 causes ADAM10-dependent ectodomain shedding of tumor necrosis factor receptor 1 in vascular smooth muscle cells. ADAM, TNF-alpha, TNFR1
98  2015 Association between plasma sLOX-1 concentration and arterial stiffness in middle-aged and older individuals. sLOX-1
99  2015 Atorvastatin protects cardiomyocytes from oxidative stress by inhibiting LOX-1 expression and cardiomyocyte apoptosis. ACS, CAD
100  2015 Coronary Microembolization Induces Cardiomyocyte Apoptosis Through the LOX-1-Dependent Endoplasmic Reticulum Stress Pathway Involving JNK/P38 MAPK. CHOP, CME, ER, GRP78, JNK, LAD, MAPK, siRNA