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[Related PubMed/MEDLINE]
Total Number of Papers: 356
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| Abbreviation |
: LRP1 |
| Long Form |
: lipoprotein receptor-related protein 1 |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2020 |
A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue plasminogen activator. |
tPA |
| 2 |
2020 |
A soluble derivative of PrPC activates cell-signaling and regulates cell physiology through LRP1 and the NMDA receptor. |
ADAM, NMDAR |
| 3 |
2020 |
Alzheimer's amyloid-beta and tau protein accumulation is associated with decreased expression of the LDL receptor-associated protein in human brain tissue. |
AD, RAP |
| 4 |
2020 |
Association of Low-Density Lipoprotein Receptor-Related Protein 1 and Its rs1799986 Polymorphism With Mild Cognitive Impairment in Chinese Patients With Type 2 Diabetes. |
AVLT, MCI, MoCA, OR, sLRP1, T2DM |
| 5 |
2020 |
CRELD2 Is a Novel LRP1 Chaperone That Regulates Noncanonical WNT Signaling in Skeletal Development. |
EGF, ER |
| 6 |
2020 |
Development of a Novel Dual-Order Protein-Based Nanodelivery Carrier That Rapidly Targets Low-Grade Gliomas with Microscopic Metastasis in Vivo. |
BBB, Fn-Rev-Ang, MRI, TfR1 |
| 7 |
2020 |
Effect of Zhenxin Xingshui Yizhi Fang on Abeta25-35 induced expression of related transporters in HBMEC cell model. |
AD, HBMEC, XSF |
| 8 |
2020 |
Efficient LRP1-mediated uptake and low cytotoxicity of peptide L57 in vitro shows its promise as CNS drug delivery vector. |
CNS |
| 9 |
2020 |
Gastrodin relieves inflammation injury induced by lipopolysaccharides in MRC-5 cells by up-regulation of miR-103. |
COPD |
| 10 |
2020 |
Gout inheritance in an extended Chinese family analyzed by whole-exome sequencing: A case-report. |
OIT3, UC |
| 11 |
2020 |
High-Affinity Binding of LDL Receptor-Related Protein 1 to Matrix Metalloprotease 1 Requires Protease:Inhibitor Complex Formation. |
ECM, MMP, TIMPs |
| 12 |
2020 |
Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5). |
BBB, BCEC, hiPSC, SLC's, TEER, TfR |
| 13 |
2020 |
Investigating the clearance of VWF A-domains using site-directed PEGylation and novel N-linked glycosylation. |
PEG, vWF |
| 14 |
2020 |
Involvement of chronic unpredictable mild stress-induced hippocampal LRP1 up-regulation in microtubule instability and depressive-like behavior in a depressive-like adult male rat model. |
CUMS |
| 15 |
2020 |
Involvement of the lipoprotein receptor LRP1 in AMP-IBP5-mediated migration and proliferation of human keratinocytes and fibroblasts. |
AMP-IBP5 |
| 16 |
2020 |
Knockdown of Lrp1 in RAW264cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions invitro. |
--- |
| 17 |
2020 |
Lactotransferrin Downregulation Drives the Metastatic Progression in Clear Cell Renal Cell Carcinoma. |
ccRCC, EMT |
| 18 |
2020 |
Low density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional receptor in heart. |
--- |
| 19 |
2020 |
Low density lipoprotein receptor-related protein 1 regulates cardiac hypertrophy induced by pressure overload. |
Ang II, NE, PE, TAC |
| 20 |
2020 |
Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity. |
FA, FAO, HFD, NPR-A, pro-ANP |
| 21 |
2020 |
LRP1 is a master regulator of tau uptake and spread. |
--- |
| 22 |
2020 |
LRP1 knockdown aggravates Abeta1-42-stimulated microglial and astrocytic neuroinflammatory responses by modulating TLR4/NF-kappaB/MAPKs signaling pathways. |
AD, IL-1beta, IL-6, MAPKs, MyD88, NF-kappaB, TLR4, TNF-alpha, TRAF6 |
| 23 |
2020 |
LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells. |
aggLDL, CE, CVD, GLUT4, IR |
| 24 |
2020 |
Lychee seed polyphenol inhibits Abeta-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction. |
AD, LSP |
| 25 |
2020 |
Midkine promotes articular chondrocyte proliferation through the MK-LRP1-nucleolin signaling pathway. |
IP, OA, rhMK |
| 26 |
2020 |
Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues? |
AD, IGFs, IRS-1, mTORC1, Pin1 |
| 27 |
2020 |
MiR-640 inhibition alleviates acute liver injury via regulating WNT signaling pathway and LRP1. |
ALI, KCs, LPS |
| 28 |
2020 |
Muramyl dipeptide-mediated immunomodulation on monocyte subsets exerts therapeutic effects in a mouse model of Alzheimer's disease. |
AD, COX2, ICAM-1, MCP-1, MDP, PSD-95 |
| 29 |
2020 |
Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening. |
CHD, CNC, OFT |
| 30 |
2020 |
Ovotransferrin Exhibits Osteogenic Activity Partially via Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Activation in MC3T3-E1 Cells. |
--- |
| 31 |
2020 |
PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer. |
EECs, PAI-1, TGF-beta |
| 32 |
2020 |
RNA Sequencing Reveals Cancer-Associated Changes in Laryngeal Cells Exposed to Non-Acid Pepsin. |
LPR |
| 33 |
2020 |
Silencing of LRP1 Exacerbates Inflammatory Response Via TLR4/NF-kappaB/MAPKs Signaling Pathways in APP/PS1 Transgenic Mice. |
AD, MAPK, NF-kappaB, TLR4 |
| 34 |
2020 |
Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery. |
EHD1, SNX, SNX17 |
| 35 |
2020 |
The active contribution of OPCs to neuroinflammation is mediated by LRP1. |
OPCs |
| 36 |
2020 |
The low density receptor-related protein 1 plays a significant role in ricin-mediated intoxication of lung cells. |
--- |
| 37 |
2020 |
The Neuroprotective Effects of Danggui-Shaoyao San on Vascular Cognitive Impairment: Involvement of the Role of the Low-Density Lipoprotein Receptor-Related Protein. |
CCH, DSS, IKK, NF-kappaB, VCI |
| 38 |
2020 |
Therapeutic Potential of Direct Clearance of the Amyloid-beta in Alzheimer's Disease. |
AD, CSF, RAGE |
| 39 |
2020 |
Two weeks of western diet disrupts liver molecular markers of cholesterol metabolism in rats. |
ACAT-2, ACC, ChREBP, HMGCoAR, LDLR, SD, SREBP2, TG |
| 40 |
2019 |
Activated alpha2-Macroglobulin Regulates LRP1 Levels at the Plasma Membrane through the Activation of a Rab10-dependent Exocytic Pathway in Retinal Muller Glial Cells. |
MGCs, PM |
| 41 |
2019 |
alpha-2-Macroglobulin induces the shedding of microvesicles from cutaneous wound myofibroblasts. |
A2M, MVs |
| 42 |
2019 |
Altered fibrinolytic system in rat models of depression and patients with first-episode depression. |
BDI, CUMS, LPS, PAI-1, PBMCs, tPA |
| 43 |
2019 |
Analysis of Comparative Proteomic and Potent Targets of Peniciketal A in Human Acute Monocytic Leukemia. |
CALR, G6PD, KEGG, Pe-A |
| 44 |
2019 |
Chronic cerebral hypoperfusion alters amyloid-beta transport related proteins in the cortical blood vessels of Alzheimer's disease model mouse. |
4-HNE, AD, CAA, CCH, EDA, GLUT1, HIF-1alpha, HO-1, Mfsd2a, RAGE, WT |
| 45 |
2019 |
Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model. |
CNS, EAE, KO, OPCs |
| 46 |
2019 |
Copper-Induced Upregulation of MicroRNAs Directs the Suppression of Endothelial LRP1 in Alzheimer's Disease Model. |
AD, MVECs |
| 47 |
2019 |
Developing LRP1 Agonists into a Therapeutic Strategy in Acute Myocardial Infarction. |
AAT, AMI, RISK |
| 48 |
2019 |
Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy. |
BBB, BCECs, CMC, MMP-2, RT |
| 49 |
2019 |
Enhanced blood-brain-barrier penetrability and tumor-targeting efficiency by peptide-functionalized poly(amidoamine) dendrimer for the therapy of gliomas. |
Ang2, BBB, CNS, EGFR, OBOC |
| 50 |
2019 |
Extracellular Hsp90alpha and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1. |
EMT |
| 51 |
2019 |
Furin-mediated cleavage of LRP1 and increase in ICD of LRP1 after cerebral ischemia and after exposure of cultured neurons to NMDA. |
ICD, NMDA, TGN |
| 52 |
2019 |
Gender difference and genetic variance in lipoprotein receptor-related protein 1 is associated with mortality. |
SNPs |
| 53 |
2019 |
Hemin induces autophagy in a leukemic erythroblast cell line through the LRP1 receptor. |
LC3, qRT-PCR, WB |
| 54 |
2019 |
Identification of hepatokines involved in pathology of type 2 diabetes and obesity. |
AMPK, LECT2, ROS, SeP |
| 55 |
2019 |
Letter by Hoekstra et al Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages". |
CCR7 |
| 56 |
2019 |
Letter by Potere et al Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages". |
CCR7 |
| 57 |
2019 |
Long-term consumption of alcohol exacerbates neural lesions by destroying the functional integrity of the blood-brain barrier. |
AQP4, BBB, Mfsd2a, RAGE |
| 58 |
2019 |
Low Density Lipoprotein Receptor-Related Protein-1 in Cardiac Inflammation and Infarct Healing. |
AAT, AMI, HF |
| 59 |
2019 |
Low Density Receptor-Related Protein 1 Interactions With the Extracellular Matrix: More Than Meets the Eye. |
ECM |
| 60 |
2019 |
Low-density lipoprotein receptor-related protein 1 regulates muscle fiber development in cooperation with related genes to affect meat quality. |
--- |
| 61 |
2019 |
Low-dose pioglitazone can ameliorate learning and memory impairment in a mouse model of dementia by increasing LRP1 expression in the hippocampus. |
AD, PPARgamma, SAMP8 |
| 62 |
2019 |
LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats. |
APOE, SAH, WMI |
| 63 |
2019 |
LRP1 Has a Predominant Role in Production over Clearance of Abeta in a Mouse Model of Alzheimer's Disease. |
AD, APP, BBB, CSF, ISF, sAPP-alpha |
| 64 |
2019 |
LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension. |
IPAH, PASMC, PDGF, PH, SMC |
| 65 |
2019 |
LRP1-upregulated nanoparticles for efficiently conquering the blood-brain barrier and targetedly suppressing multifocal and infiltrative brain metastases. |
BBB, BMECs |
| 66 |
2019 |
Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. |
EAM, MK, NETs, PMNs |
| 67 |
2019 |
Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation. |
GFC, GGE, HPTLC, PLA2, TEM |
| 68 |
2019 |
Overexpression of PID1 reduces high density lipoprotein level and functionality in swine. |
apoA-I, HDL-C, PID1, PTB |
| 69 |
2019 |
Paricalcitol accelerates BACE1 lysosomal degradation and inhibits calpain-1 dependent neuronal loss in APP/PS1 transgenic mice. |
BACE1, BER, PAL, SREBP2 |
| 70 |
2019 |
Recombinant expressing angiopep-2 fused anti-VEGF single chain Fab (scFab) could cross blood-brain barrier and target glioma. |
ANG, scFab, scFab |
| 71 |
2019 |
Response by Mueller et al to Letter Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages". |
CCR7 |
| 72 |
2018 |
A Novel Delivery System of Cyclovirobuxine D for Brain Targeting: Angiopep-Conjugated Polysorbate 80-Coated Liposomes via Intranasal Administration. |
ANG, BBB, LPs, TEM |
| 73 |
2018 |
A novel peptide ligand RAP12 of LRP1 for glioma targeted drug delivery. |
BBB, BBTB, RAP, VM |
| 74 |
2018 |
Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation. |
APOE |
| 75 |
2018 |
Beneficial Role of Rosuvastatin in Blood-Brain Barrier Damage Following Experimental Ischemic Stroke. |
BBB, MAPK, MCAO, MMPs, p-ERK, p-JNK, PDGFRalpha, rt-PA, TIMPs |
| 76 |
2018 |
Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-beta42 by LRP1-dependent apolipoprotein E isoform-specific mechanism. |
APOE, BBB |
| 77 |
2018 |
Bovine lactoferrin promotes energy expenditure via the cAMP-PKA signaling pathway in human reprogrammed brown adipocytes. |
bLF, cAMP, CREB, LF, PGC1alpha, RAP, UCP1 |
| 78 |
2018 |
Cerebrovascular Angiogenic Reprogramming upon LRP1 Repression: Impact on Sphingosine-1-Phosphate-Mediated Signaling in Brain Endothelial Cell Chemotactism. |
S1P |
| 79 |
2018 |
Chronic Arsenic Exposure Increases Abeta(1-42) Production and Receptor for Advanced Glycation End Products Expression in Rat Brain. |
RAGE |
| 80 |
2018 |
Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of beta-amyloid. |
AD, CSF, i.c.v, LiCl, WT |
| 81 |
2018 |
Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages. |
CCR7 |
| 82 |
2018 |
Design of multifunctional peptide collaborated and docetaxel loaded lipid nanoparticles for antiglioma therapy. |
GBM, SLN |
| 83 |
2018 |
Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells. |
DOX |
| 84 |
2018 |
Liver-enriched transcription factor expression relates to chronic hepatic failure in humans. |
CDH1, CEBP, CYP3A4, FOXA2, HNF, LETFs, OTC, pMLC |
| 85 |
2018 |
Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. |
HFHC |
| 86 |
2018 |
LRP1: A chameleon receptor of lung inflammation and repair. |
--- |
| 87 |
2018 |
Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice. |
--- |
| 88 |
2018 |
Macrophage LRP1 Promotes Diet-Induced Hepatic Inflammation and Metabolic Dysfunction by Modulating Wnt Signaling. |
--- |
| 89 |
2018 |
Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation. |
AML, mP3, PMN |
| 90 |
2018 |
Overexpression of low density lipoprotein receptor-related protein 1 (LRP1) is associated with worsened prognosis and decreased cancer immunity in clear-cell renal cell carcinoma. |
ccRCC, MVD, TIL |
| 91 |
2018 |
p53 Regulates the Expression of LRP1 and Apoptosis through a Stress Intensity-Dependent MicroRNA Feedback Loop. |
--- |
| 92 |
2018 |
Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-beta pathology in amyloid model mice. |
AD |
| 93 |
2018 |
PID1 in adipocytes modulates whole-body glucose homeostasis. |
aP2-PID1tg, IR, PID1, WAT |
| 94 |
2018 |
Regulatory effects of simvastatin and apoJ on APP processing and amyloid-beta clearance in blood-brain barrier endothelial cells. |
AD, APP, BBB, BCEC, CAA |
| 95 |
2018 |
Synergistic role of HSP90alpha and HSP90beta to promote myofibroblast persistence in lung fibrosis. |
ECM, HSP, IPF |
| 96 |
2018 |
The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM. |
AD, BBB |
| 97 |
2018 |
TLR Crosstalk Activates LRP1 to Recruit Rab8a and PI3Kgamma for Suppression of Inflammatory Responses. |
GTPase, PI3K, TLRs |
| 98 |
2018 |
Vitamin K2 improves proliferation and migration of bovine skeletal muscle cells in vitro. |
LDH, LDLR |
| 99 |
2018 |
Voltage-gated calcium channel alpha 2delta subunits: an assessment of proposed novel roles. |
NMDA |
| 100 |
2018 |
ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells. |
EMT, FN1, ITGB1, miRNAs, VM, ZEB1 |
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