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Abbreviation : LTC
Long Form : long-term culture
No. Year Title Co-occurring Abbreviation
2017 Establishment and Characterization of Long-Term Cultures Derived from Primary Acute Myeloid Leukemia Cells for HDAC Inhibitor Research. AML, HDAC
2017 Overview of Chromosome Abnormalities in First Trimester Miscarriages: A Series of 1,011 Consecutive Chorionic Villi Sample Karyotypes. STC
2016 Involvement of urokinase receptor in the cross-talk between human hematopoietic stem cells and bone marrow microenvironment. AML, BM, HSCs
2016 Quantitation of Human Cells that Produce Neutrophils and Platelets in Vivo Obtained from Normal Donors Treated with Granulocyte Colony-Stimulating Factor and/or Plerixafor. ---
2016 Quantitative fluorescent polymerase chain reaction for rapid prenatal diagnosis of fetal aneuploidies in chorionic villus sampling in a single institution. CVS, QF-PCR
2016 Ubiquitous Chromatin Opening Elements (UCOEs) effect on transgene position and expression stability in CHO cells following methotrexate (MTX) amplification. MTX, UCOEs
2015 Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy. HSC
2013 Human long-term culture initiating cell assay. LTC-IC
2012 Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture. CHO
10  2012 Is routine karyotyping required in prenatal samples with a molecular or metabolic referral? CV, STC
11  2011 Identification of a novel antigen cross-presenting cell type in spleen. APC, DC
12  2010 Maintenance and characterization of lymphocytes in human long term bone marrow cultures to study immunotoxicity. ---
13  2010 Stem cell traits in long-term co-culture revealed by time-lapse imaging. CAFC, CAs, COS, HPCs, HSCs, LT, ST
14  2009 Detection of chromosome aneuploidies in chorionic villus samples by multiplex ligation-dependent probe amplification. MLPA, STC
15  2009 Ex vivo assays to study self-renewal and long-term expansion of genetically modified primary human acute myeloid leukemia stem cells. AML, L-CA
16  2009 The replacement of cytogenetic analysis by direct chorionic villi sampling preparation with quantitative fluorescence PCR. CV, DIR, QF-PCR
17  2008 Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursors. EC, HPC
18  2008 Influence of mesenchymal stem cells derived from bone marrow of children with oncohematological diseases on proliferation and self-renewal of hematopoietic progenitor cells in vitro. BM, HSCs, MSCs
19  2008 Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. BM, GFRs, GFs, HSCs, miRNA, MSCs
20  2007 Hematopoiesis of immature myeloid dendritic cells in stroma-dependent spleen long-term cultures occurs independently of NF-KB/RelB function. DC, NF-kB
21  2007 Mycoplasma contaminants present in exosome preparations induce polyclonal B cell responses. CSN, DC, FO, MZ
22  2006 Heterogeneity amongst splenic stromal cell lines which support dendritic cell hematopoiesis. DC
23  2006 Role of stromal-derived factor-1 in the hematopoietic-supporting activity of human mesenchymal stem cells. HSPC, IC, IL, MSC, SDF-1
24  2005 Bone marrow clonogenic capability, cytokine production, and thymic output in patients with common variable immunodeficiency. BM, CFC
25  2005 Posttransplant hematopoiesis in patients undergoing sibling allogeneic stem cell transplantation reflects that of their respective donors although with a lower functional capability. allo-SCT, BM
26  2005 The immunogenicity of dendritic cell-derived exosomes. DC, MVE
27  2004 Dendritic cell development in long-term spleen stromal cultures. DCs
28  2004 Expression of bone morphogenetic proteins in stromal cells from human bone marrow long-term culture. ALK-3, BMPs, IHC
29  2004 Improved gene transfer and normalized enzyme levels in primitive hematopoietic progenitors from patients with mucopolysaccharidosis type I using a bioreactor. CFC, HBS, HSC, LTC-IC, MPS, MPS I
30  2004 In vitro hematopoiesis produces a distinct class of immature dendritic cells from spleen progenitors with limited T cell stimulation capacity. DC, HEL
31  2004 Prenatal diagnosis of DMD in a female foetus affected by Turner syndrome. ---
32  2004 Quiescent (5-fluorouracil-resistant) aplastic anemia hematopoietic cells in vitro. AA, HSC
33  2003 Identification of differentially expressed genes representing dendritic cell precursors and their progeny. DCs, MHC2lo, PCR
34  2003 Mobilized peripheral blood SSCloALDHbr cells have the phenotypic and functional properties of primitive haematopoietic cells and their number correlates with engraftment following autologous transplantation. ALDH, BAAA, CFU, PBSC, SSC
35  2003 Supplementation of conventional freezing medium with a combination of catalase and trehalose results in better protection of surface molecules and functionality of hematopoietic cells. CB/FL, DMSO, IL-3, MNC, SCF
36  2003 The establishment and characterization of an immortal cell line with a stable chondrocytic phenotype. RCS
37  2002 Bone and bone marrow interactions: hematological activity of osteoblastic growth peptide (OGP)-derived carboxy-terminal pentapeptide. II. Action on human hematopoietic stem cells. BFU, CFU, OGP, SCF
38  2002 Frequency and differentiation capacity of circulating LTC-IC mobilized by G-CSF or GM-CSF following chemotherapy: a comparison with steady-state bone marrow and peripheral blood. BM, LDA, PB
39  2002 Long-term culture-initiating cell assays for human and murine cells. ---
40  2002 MEK-ERK pathway is expressed but not activated in high proliferating, self-renewing cord blood hematopoietic progenitors. ERK, HP, MAP, SCF, TPO
41  2002 Polyclonal normal hematopoietic progenitors in patients with acute myeloid leukemia. AML, AR, BM, CFC, HUMARA, PB
42  2002 [Screening of differentially expressed genes in the mouse hematopoietic stromal cells after long-term culture]. BMC, HSC, SSH
43  2001 Bone Marrow Cells Activated by Autologous Dendritic Cells Purges Bone Marrow from Patients with Chronic Myelogenous Leukemia BMMNCs, CML, DCs, RT-PCR
44  2001 Bone marrow stromal dysfunction in mice administered cytosine arabinoside. BM, CM, HPPC
45  2001 Optimization of retroviral gene transfer protocol to maintain the lymphoid potential of progenitor cells. HPCs, M-GDF, SCF
46  2000 Blood-derived macrophage layers in the presence of hydrocortisone support myeloid progenitors in long-term cultures of CD34+ cord blood and bone marrow cells. BM, CB, CFU-GM, PB
47  2000 Cutting edge: resistance to apoptosis and continuous proliferation of dendritic cells deficient for TNF receptor-1. DC
48  2000 Identification of progenitor cells in long-term spleen stromal cultures that produce immature dendritic cells. DC, FcR
49  2000 Improved FACS analysis confirms generation of immature dendritic cells in long-term stromal-dependent spleen cultures. DC
50  2000 Morphologic, immunophenotypic and in vitro growth characteristics of blood and bone marrow associated with stem cell mobilisation in patients with lymphoma. BM
51  2000 Proliferation of dendritic cell progenitors in long term culture is not dependent on granulocyte macrophage-colony stimulating factor. DC, GM-CSF
52  2000 Quantitation of primitive and lineage-committed progenitors in mobilized peripheral blood for prediction of platelet recovery post autologous transplant. ANC, CFC-Mk
53  2000 Stable marker gene transfer into human bone marrow stromal cells and their progenitors using novel herpesvirus saimiri-based vectors. BM, CFU-F, GFP, HVS, MOI
54  2000 Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells. AML, CFC, GM-CSF
55  1999 CD34high+ CD38(low/-) cells generated in a xenogenic coculture system are capable of both long-term hematopoiesis and multiple differentiation. HPP-CFCs, HUCB
56  1999 Embryonic stem cells release potentially novel hematopoietic factors. ES, est.LTC-IC
57  1999 Enforced expression of HOXB7 promotes hematopoietic stem cell proliferation and myeloid-restricted progenitor differentiation. CFU-GM, GM, HPP-CFC, LTC-ICs, PB
58  1999 Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells. ---
59  1999 Favorable therapeutic index of a p210(BCR-ABL)-specific tyrosine kinase inhibitor; activity on lineage-committed and primitive chronic myelogenous leukemia progenitors. CFC, CML, PBPC
60  1999 Immunotherapeutic potential of dendritic cells generated in long-term stroma-dependent cultures. APC, CTL, DC
61  1999 KDR receptor: a key marker defining hematopoietic stem cells. BM, HPCs, HSCs
62  1999 Long-term stroma-dependent cultures are a consistent source of immunostimulatory dendritic cells. DC
63  1999 Long-term survival, morphology and in vitro function of isolated pig islets under different culture conditions. IEQ, NCS
64  1999 Selection of BCR/ABL-negative stem cells from marrow or blood of patients with chronic myeloid leukemia. 5-FU, CML, MNC, Ph
65  1999 [Analysis of hemopoietic progenitor cells in bone marrow and peripheral blood samples which have undergone different periods of cryopreservation]. ABMT, BM, PBSC
66  1998 An in vitro model for cytogenetic conversion in CML. Interferon-alpha preferentially inhibits the outgrowth of malignant stem cells preserved in long-term culture. CAFC, FISH, NC, Ph
67  1998 Analysis of peripheral blood CD34+ cells mobilized with granulocyte colony-stimulating factor (G-CSF) using a long-term culture system. BFU-E, CFU-GM, G-CSF, LTC-IC, MNCs, PBSCT
68  1998 Comparative effects of retroviral-mediated gene transfer into primary human stromal cells of Flt3-ligand, interleukin 3 and GM-CSF on production of cord blood progenitor cells in long-term culture. IL-3
69  1998 False-negative findings in chorionic villus sampling. An experimental approach and review of the literature. AC, CVS, PUBS
70  1998 MCP-1, not MIP-1alpha, is the endogenous chemokine that cooperates with TGF-beta to inhibit the cycling of primitive normal but not leukemic (CML) progenitors in long-term human marrow cultures. CML, CML, MCP-1, MIP-1alpha, TGF-beta
71  1998 Pre-treatment of peripheral blood progenitor cells with macrophage inflammatory protein-1alpha induces prolonged survival of early progenitor cells over 6 weeks of long-term culture. BM, CAFC, CFC, IL, LTC-IC, MIP-1alpha, PBPC
72  1998 Retroviral transfer and long-term expression of the adrenoleukodystrophy gene in human CD34+ cells. ALD, VLCFAs
73  1998 Stimulatory effects of hepatocyte growth factor on hemopoiesis of SCF/c-kit system-deficient mice. BM, HGF, HSCs
74  1998 Stroma-contact prevents loss of hematopoietic stem cell quality during ex vivo expansion of CD34+ mobilized peripheral blood stem cells. CAFC, HSC, IL-3, PBSC
75  1997 Autografting in Philadelphia (Ph)+ chronic myeloid leukaemia using cultured marrow: an update of a pilot study. LTC-IC, Ph
76  1997 Cytokine responsiveness of primitive progenitors in acute myelogenous leukemia. AML
77  1997 Diverse effects of anti-CD44 antibodies on the stromal cell-mediated support of normal but not leukaemic (CML) haemopoiesis in vitro. CFC, CML, LTC-IC
78  1997 Does transmembrane communication through gap junctions enable stem cells to overcome stromal inhibition? AB, CFU-C, CM, GJIC, HSC
79  1997 Efficient long-term maintenance of chronic myeloid leukemic cobblestone area forming cells on a murine stromal cell line. BM, CAFC, CML, FISH, PB, wk-1
80  1997 Ex vivo expansion of CD34 + CD38- cord blood cells. anti-TGF-beta, CB, GM-CSF, IL-3, SCF
81  1997 Long-term stromal cultures produce dendritic-like cells. DC, IL, MO
82  1997 Stromal cells negatively regulate primitive haemopoietic progenitor cell activation via a phosphatidylinositol-anchored cell adhesion/signalling mechanism. H'ase, PI-PLC
83  1996 Cryopreserved human bone marrow stroma is fully functional in vitro. LTC-IC, NBM
84  1996 Early suppressive effects of chemotherapy and cytokine treatment on committed versus primitive haemopoietic progenitors in patient bone marrow. CFU-GM, FLAC
85  1996 Evaluation of cytogenetic conversion to Ph- haemopoiesis in long-term bone marrow culture for patients with chronic myeloid leukaemia on conventional hydroxyurea therapy, on pulse high-dose hydroxyurea and on interferon-alpha. CML, HU, IFN, LTBMC, P-HU
86  1996 Individual stem cell quality in leukapheresis products is related to the number of mobilized stem cells. CAFC, CFC, LPs, PBSC
87  1995 Analysis of cord blood CD34+ cells purified after cryopreservation. CB, LTC-IC
88  1995 Cytokine production in long-term marrow cultures after autologous bone marrow transplantation. BMT, CFU-GM, G-CSF, GM-CSF, LTBMC, TNF-alpha
89  1995 Density separation of umbilical cord blood and recovery of hemopoietic progenitor cells: implications for cord blood banking. CB, CFUs, RBC, SCF
90  1995 Negative regulators may mediate some of the inhibitory effects of HIV-1 infected stromal cell layers on erythropoiesis and myelopoiesis in human bone marrow long term cultures. BFU-E, CFU-GM, HIV, IL-4, TNF-alpha
91  1995 Quantitative and qualitative comparative analysis of gradient-separated hematopoietic cells from cord blood and chemotherapy-mobilized peripheral blood. CB, CFC, CFU-GM, MNC, PB, SC
92  1994 Autologous bone marrow transplantation in ALL: relapse linked to infusion of tumor cells with the back-up marrow. ABMT, CR
93  1994 Behavior in vitro of long-term cultured bone marrow or blood cells from chronic myeloid leukemia: adhesion molecules and differentiation antigens as detected by immunocytochemistry. EBV
94  1994 Characterization of peripheral blood CD34+ progenitor cells mobilized with chemotherapy and granulocyte colony-stimulating factor. BM, CFU-GM, G-CSF, GM-CSF, IL-3, MC, PB, SCF
95  1994 Cytokines acting early in human haematopoiesis. ---
96  1994 Interleukin-2 activation of human bone marrow in long-term cultures: an effective strategy for purging and generation of anti-tumor cytotoxic effectors. ---
97  1994 Long-term culture and molecular biological studies highlight differences in relative BCR-ABL expression levels in the peripheral blood and bone marrow of a patient with chronic granulocytic leukaemia. CGL
98  1994 Persistence of bcr-abl mRNA-expressing cells in long-term cultures established from chronic myeloid leukemic bone marrow or blood. CML, PCR
99  1994 Plastic-adherent cells in human bone marrow generate long-term hematopoiesis in vitro. P delta
100  1993 Autografting in chronic myeloid leukemia with cultured marrow: update of the Vancouver Study. CML, CP, IFN-alpha, LTC-IC, Ph