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Abbreviation : MAPT
Long Form : microtubule-associated protein tau
No. Year Title Co-occurring Abbreviation
2020 A system-level approach to investigate alloxan-induced toxicity in microtubule-binding protein to lead type 2 diabetes mellitus. ---
2020 Actin-mediated Microglial Chemotaxis via G-Protein Coupled Purinergic Receptor in Alzheimer's Disease. AD, NFTs, NO, PTMs, ROS
2020 Biomarkers of Neurological Outcome After Aneurysmal Subarachnoid Hemorrhage as Early Predictors at Discharge from an Intensive Care Unit. aSAH, AUC, GFAP, GOS, ICU, NSE
2020 Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort. bvFTD, C9orf72, FTD, NPI-Q
2020 Development of Novel Chemically-Modified Nucleic Acid Molecules for Efficient Inhibition of Human MAPT Gene Expression. 2'-OMe, AOs, PS
2020 Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration. C9orf72, FTD
2020 Effect of Phosphorylation and O-GlcNAcylation on Proline-Rich Domains of Tau. PTMs
2020 Erosion of Gene Co-expression Networks Reveal Deregulation of Immune System Processes in Late-Onset Alzheimer's Disease. HLA, LOAD, NGS, QC, ROSMAP
2020 Fibrillation and molecular characteristics are coherent with clinical and pathological features of 4-repeat tauopathy caused by MAPT variant G273R. CBD, MTs, PSP
10  2020 Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases. C9orf72, FTD, LEFFTDS, PSEN1, TARDBP, VCP
11  2020 Genetics of Progressive Supranuclear Palsy: A Review. DCTN1, GWAS, LRRK2, PSP
12  2020 Interaction of APOE4 alleles and PET tau imaging in former contact sport athletes. APOE, SUVRs
13  2020 Involvement of hippocampal agmatine in beta1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice. AD, BACE 1, BDNF, IL-6, NOR, RAM, TNF-alpha
14  2020 Long non-coding RNA 00507/miRNA-181c-5p/TTBK1/MAPT axis regulates tau hyperphosphorylation in Alzheimer's disease. AD, APP, ceRNA, TTBK1
15  2020 Meridianins and Lignarenone B as Potential GSK3beta Inhibitors and Inductors of Structural Neuronal Plasticity. AD, GSK-3, NFT
16  2020 Microtubule-associated protein tau (MAPT) is a promising independent prognostic marker and tumor suppressive protein in clear cell renal cell carcinoma. ccRCC
17  2020 Microtubule-associated protein tau (MAPT) promotes bicalutamide resistance and is associated with survival in prostate cancer. PTEN
18  2020 Modeling of Frontotemporal Dementia Using iPSC Technology. Bax, bvFTD, FTD, FUS, iPSN, STS, TAR
19  2020 New-Onset Delusions Heralding an Underlying Neurodegenerative Condition: A Case Report and Review of the Literature. bvFTD, bvFTD, FTD
20  2020 Nimodipine Improves Cognitive Impairment After Subarachnoid Hemorrhage in Rats Through IncRNA NEAT1/miR-27a/MAPT Axis. CI, NEAT1, SAH
21  2020 Orthosiphon stamineus Standardized Extract Reverses Streptozotocin-induced Alzheimer's Disease-Like Condition in a Rat Model. AD, APP, GSK3alpha, GSK3beta, i.c.v, NFTs, STZ
22  2020 Phenotype Heterogeneity and Genotype Correlation of MAPT Mutations in a Chinese PUMCH Cohort. FTD, NGS
23  2020 Picalm reduction exacerbates tau pathology in a murine tauopathy model. AD, Ass, FTLD-tau, GWAS
24  2020 PKR kinase directly regulates tau expression and Alzheimer's disease-related tau phosphorylation. PKR
25  2020 Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells. AD, APP, GSAP, MHNCs, Pja2
26  2020 Screening non-MAPT genes of the Chr17q21 H1 haplotype in Parkinson's disease. CADD, LD, LOPD, PD
27  2020 Staufen 1 amplifies proapoptotic activation of the unfolded protein response. ER, HTT, PSEN1, STAU1, TARDBP, UPR
28  2020 Tau PET Imaging with [18F]PM-PBB3 in Frontotemporal Dementia with MAPT Mutation. FTD, PBB3, PET
29  2020 The behavioural phenotype of 14-month-old female TAU58/2 transgenic mice. AD, FTD, NFT's
30  2020 The cerebral blood flow deficits in Parkinson's disease with mild cognitive impairment using arterial spin labeling MRI. ASL-MRI, CBF, DAN, DMN, HC, PD, PH, VN
31  2020 The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas. AMP, EGFR, mut, NF-kappaB, TAZ, WT
32  2020 To Elucidate the Inhibition of Excessive Autophagy of Rhodiola crenulata on Exhaustive Exercise-Induced Skeletal Muscle Injury by Combined Network Pharmacology and Molecular Docking. AMPK, BECN1, DAVID, FoxO, mTOR, PPI, R. crenulata, SIRT1
33  2019 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes. AD, bvFTD, C9orf72, CBS, FTD, nfvPPA, PET, svPPA
34  2019 A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. CBD, FTLD-Tau, iPSC, NPCs, PSP
35  2019 Aberrant expression of the microtubule-associated protein tau is an independent prognostic feature in prostate cancer. ---
36  2019 Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics. AD
37  2019 Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics. AD
38  2019 Amyotrophic Lateral Sclerosis-associated GGGGCC repeat expansion promotes Tau phosphorylation and toxicity. ALS, C9orf72, FTD
39  2019 An update on genetic frontotemporal dementia. bvFTD, C9orf72, FPI, FTD
40  2019 Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology. PSP
41  2019 BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes. p-Ser262
42  2019 Computational Investigation of RNA A-Bulges Related to the Microtubule-Associated Protein Tau Causing Frontotemporal Dementia and Parkinsonism. ---
43  2019 Concentration of microtubule associated protein tau (MAPT) in urine and saliva as a potential biomarker of traumatic brain injury in relationship with blood-brain barrier disruption in postmortem examination. TBI
44  2019 Frontal lobe 1H MR spectroscopy in asymptomatic and symptomatic MAPT mutation carriers. Cr, LEFFTDS, mI, NAA
45  2019 Gene mutations in a Han Chinese Alzheimer's disease cohort. AD, APP, EOAD, LOAD, PSEN1, PSEN2, TBK1
46  2019 Genetic predictors of survival in behavioral variant frontotemporal degeneration. bvFTD, CI, HR
47  2019 Genetic Variation in the Ontario Neurodegenerative Disease Research Initiative. AD, APOE, FTD, MCI
48  2019 HLA and microtubule-associated protein tau H1 haplotype associations in anti-IgLON5 disease. ---
49  2019 Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation. AD, APP
50  2019 Identification of target genes in neuroinflammation and neurodegeneration after traumatic brain injury in rats. APOE, DEGs, TBI
51  2019 Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations. MT
52  2019 Longitudinal multimodal MRI as prognostic and diagnostic biomarker in presymptomatic familial frontotemporal dementia. ---
53  2019 MAPT (Tau) expression is a biomarker for an increased rate of survival for low‑grade glioma. LGG
54  2019 MAPT p.V363I mutation: A rare cause of corticobasal degeneration. CBD, CBS
55  2019 MAPT promoter CpG island hypermethylation is associated with poor prognosis in patients with stage II colorectal cancer. CIMP, CRC, OS
56  2019 MAPT rs242557 variant is associated with hippocampus tau uptake on 18F-AV-1451 PET in non-demented elders. ROIs, SUVRs
57  2019 Mitophagy and NAD+ inhibit Alzheimer disease. AD
58  2019 Multimodal MRI of grey matter, white matter, and functional connectivity in cognitively healthy mutation carriers at risk for frontotemporal dementia and Alzheimer's disease. AD, APOE4, FTD, MRI, TBSS
59  2019 Negative-feedback coordination between proteasomal activity and autophagic flux. UPS, USP14
60  2019 Overexpression of MAPT-AS1 is associated with better patient survival in breast cancer. lncRNA, TNBC
61  2019 Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs. AD, FTD, iPSC
62  2019 Rates of lobar atrophy in asymptomatic MAPT mutation carriers. ---
63  2019 Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism. FTD
64  2019 Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport. WT
65  2019 Tauopathy in basal ganglia involvement is exacerbated in a subset of patients with Alzheimer's disease: The Hisayama study. AD
66  2019 The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau). LIR
67  2019 The Link Between Tau and Insulin Signaling: Implications for Alzheimer's Disease and Other Tauopathies. AD
68  2019 The MAPT H1 Haplotype Is a Risk Factor for Alzheimer's Disease in APOE epsilon4 Non-carriers. DEGESCO
69  2019 Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers. DTI, MD, WM
70  2018 11C-CFT-PET in Presymptomatic FTDP-17: A Potential Biomarker Predicting Onset. FTDP-17
71  2018 Altered microRNA, mRNA, and Protein Expression of Neurodegeneration-Related Biomarkers and Their Transcriptional and Epigenetic Modifiers in a Human Tau Transgenic Mouse Model in Response to Developmental Lead Exposure. AbetaPP, AD, DNMT, MeCP2, PND, qPCR, Sp1
72  2018 Association of MAPT haplotype-tagging polymorphisms with cerebrospinal fluid biomarkers of Alzheimer's disease: A preliminary study in a Croatian cohort. Abeta1-42, AD, CSF, HC, MCI, t-tau, VILIP-1
73  2018 Association of microtubule-associated protein tau gene polymorphisms with the risk of sporadic Alzheimer's disease: a meta-analysis. CIs, ORs, SAD
74  2018 Autoimmunity and Frontotemporal Dementia. C9orf72, CNS, FTD, GRN, TDP-43
75  2018 Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion. AD, SNAREs
76  2018 Collapsin Response Mediator Protein 1, a Novel Marker Protein for Differentiated Odontoblasts. CRMP1
77  2018 Convergent total synthesis of () myricanol, a cyclic natural diarylheptanoid. AD
78  2018 CYP3A5 genotype and its impact on vincristine pharmacokinetics and development of neuropathy in Kenyan children with cancer. MDR1, PK, VCR, VIPN
79  2018 Degradation or aggregation: the ramifications of post-translational modifications on tau. AD, NFTs, PHFs, PTMs
80  2018 Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies. FTDP-17
81  2018 Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales. C9orf72, GENFI
82  2018 Dual Function of USP14 Deubiquitinase in Cellular Proteasomal Activity and Autophagic Flux. ---
83  2018 Frequency of frontotemporal dementia gene variants in C9ORF72, MAPT, and GRN in academic versus commercial laboratory cohorts. FTLD
84  2018 Genetic polymorphisms associated with the risk of concussion in 1056 college athletes: a multicentre prospective cohort study. ---
85  2018 Heparan Sulfate as a Therapeutic Target in Tauopathies: Insights From Zebrafish. AD, HSs, PSP
86  2018 Identification of biomarkers for childhood obesity based on expressional correlation and functional similarity. CE, DEGs, SKA1, SPTBN1
87  2018 In vivo 18F-AV-1451 tau PET signal in MAPT mutation carriers varies by expected tau isoforms. AD, CN
88  2018 Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP. FTLD-tau, GABA, iPSC
89  2018 Marked Reduction in the Striatal Dopamine Transporter Uptake During the Early Stage of Motor Symptoms in Patients with the MAPT N279K Mutation. DAT
90  2018 Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency. AD
91  2018 Noncoding RNAs in Alzheimer's disease. AD, APP, circRNAs, lncRNAs, miRNAs, nc, NFTs
92  2018 Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies. FTLD, FTLD-tau
93  2018 Tau in neurodegenerative disease. AD, CBD, FTDP-17, NFTs, PiD, PSP
94  2018 Tau-Induced Pathology in Epilepsy and Dementia: Notions from Patients and Animal Models. AD, FTD, FTDP-17, LBD, PSP
95  2018 Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. PSP
96  2018 The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease. AD, CM, FRET, IL-1 beta, LPS, TNF-alpha
97  2018 Traumatic Brain Injury in hTau Model Mice: Enhanced Acute Macrophage Response and Altered Long-Term Recovery. dpi, TBI
98  2018 Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migration. APP, E2F1, FABP5, HIF-1alpha, HMGA1, KD, L1CAM, MYCN, SP1
99  2018 V363I and V363A mutated tau affect aggregation and neuronal dysfunction differently in C. elegans. ---
100  2017 A novel frameshift GRN mutation results in frontotemporal lobar degeneration with a distinct clinical phenotype in two siblings: case report and literature review. CBS