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Abbreviation : MT
Long Form : mutant
No. Year Title Co-occurring Abbreviation
2020 DNMT3A mutants provide proliferating advantage with augmentation of self-renewal activity in the pathogenesis of AML in KMT2A-PTD-positive leukemic cells. AML, DNMT3A
2020 Highly sensitive mutation quantification by high-dynamic-range capillary-array electrophoresis (HiDy CE). HiDy CE, WT
2020 Interaction between IDH1 WT and calmodulin and its implications for glioblastoma cell growth and migration. 2-HG, CaM, IDH, TFP, WT
2019 Cell-Genotype Specific Effects of Mecp2 Mutation on Spontaneous and Nicotinic Acetylcholine Receptor-Evoked Currents in Medial Prefrontal Cortical Pyramidal Neurons in Female Rett Model Mice. mPFC, nAChR, RTT, WT, WTM
2019 High expression of RAD51 promotes DNA damage repair and survival in KRAS-mutant lung cancer cells. HR, WT
2019 Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1. ALS, mRNA, SOD1, WT
2019 Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas. MRI, MxIF, wt
2019 Mutated p53 Promotes the Symmetric Self-Renewal of Cisplatin-Resistant Lung Cancer Stem-Like Cells and Inhibits the Recruitment of Macrophages. Cr-LCSCs, CSCs, WT
2019 Novel mTORC1 Mechanism Suggests Therapeutic Targets for COMPopathies. COMP, ER, MID1, mTORC1, PP2A, TNF-alpha
10  2019 Phase II, 2-stage, 2-arm, PIK3CA mutation stratified trial of MK-2206 in recurrent endometrial cancer. ORR, PI3K, PR, WT
11  2019 Phenotypic Switching of Naive T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS. KRAS, NSCLC
12  2019 Rotigotine suppresses sleep-related muscle activity augmented by injection of dialysis patients' sera in a mouse model of restless legs syndrome. NREM, REM, RLS, WT
13  2019 Single chain variable fragment antibodies directed against SOD1 ameliorate disease in mutant SOD1 transgenic mice. FALS, scFvs
14  2019 Systemic screening identifies GABRD, a subunit gene of GABAA receptor as a prognostic marker in adult IDH wild-type diffuse low-grade glioma. LGG, OS, TIM, WT
15  2019 Targeting beta-catenin overcomes MEK inhibition resistance in colon cancer with KRAS and PIK3CA mutations. ---
16  2019 The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. mTORC2, WT
17  2019 The role of p53 isoforms' expression and p53 mutation status in renal cell cancer prognosis. NAT, RCC, WT
18  2018 3D Culture Represents Apoptosis Induced by Trastuzumab Better than 2D Monolayer Culture. HER2, PI3K
19  2018 Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis. WT
20  2018 beta-Catenin-RAS interaction serves as a molecular switch for RAS degradation via GSK3beta. CRC, GSK3beta
21  2018 De novo assembly and comparative transcriptome analysis reveals genes potentially involved in tissue-color changes in centipedegrass (Eremochloa ophiuroides [Munro] Hack.). DEGs, WT
22  2018 Effect of Primary Tumor Location on Second- or Later-line Treatment Outcomes in Patients With RAS Wild-type Metastatic Colorectal Cancer and All Treatment Lines in Patients With RAS Mutations in Four Randomized Panitumumab Studies. mCRC, WT
23  2018 Growth Suppression of Human Colorectal Cancer Cells with Mutated KRAS by 3-Deaza-cytarabine in 3D Floating Culture. BrUrd, CRC, EdU, WT
24  2018 HBV pre-core mutant in genotype-D infected children is selected during HBeAg/anti-HBe seroconversion and leads to HBeAg negative chronic hepatitis B in adulthood. pre-C mt, SC
25  2018 Insight into the substrate specificity change caused by the Y227H mutation of alpha-glucosidase III from the European honeybee (Apis mellifera) through molecular dynamics simulations. HBGases
26  2018 Poloxamer 188 decreases membrane toxicity of mutant SOD1 and ameliorates pathology observed in SOD1 mouse model for ALS. FALS, PG
27  2018 Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli. CFU, E. coli, MIC, PK/PD, WT
28  2018 Short-Chain Fatty Acids Alter Metabolic and Virulence Attributes of Borrelia burgdorferi. ct, OspC, SCFA
29  2018 Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified According to Kohne Prognostic Category and BRAF Mutation Status. CI, HRs, mCRC, OS, PFS, RAS, WT
30  2018 USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells. TKI, TKIs, WT
31  2017 Anti-tumor effects of NVP-BKM120 alone or in combination with MEK162 in biliary tract cancer. BTC, PI3K, WT
32  2017 Apremilast Induces Apoptosis of Human Colorectal Cancer Cells with Mutant KRAS. CRC, KRAS, PDE4B2, WT
33  2017 EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork-Associated DNA Damage Repair. HBEC, NSCLC, WT
34  2017 Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation. FGFR2
35  2017 Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I. DD-I
36  2017 Piezoelectric Plate Sensor (PEPS) for Analysis of Specific KRAS Point Mutations at Low Copy Number in Urine Without DNA Isolation or Amplification. FRMs, LNA, nt, PEPS, WT
37  2017 Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis. miRNAs, MM, WT
38  2017 Stable cell lines of human SH-SY5Y uniformly expressing wild-type or mutant-type FERM domain containing 7 gene. FRMD7, GTPases, ICN, WT
39  2017 The Role of N-Acetyl Transferases on Isoniazid Resistance from Mycobacterium tuberculosis and Human: An In Silico Approach. Mtb, NAT, WT
40  2016 Amplification-free in situ KRAS point mutation detection at 60 copies per mL in urine in a background of 1000-fold wild type. FRMs, LNA, nt, PEPS, WT
41  2016 EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer. WT
42  2016 Gene therapy by proteasome activator, PA28gamma, improves motor coordination and proteasome function in Huntington's disease YAC128 mice. BDNF, HD, LM, MSNs, NIIs, PA, PGPH, UPS
43  2016 Histological and Molecular Characterization of Grape Early Ripening Bud Mutant. MSAP, WT
44  2016 Impact of tumour RAS/BRAF status in a first-line study of panitumumab + FOLFIRI in patients with metastatic colorectal cancer. AREG, HR, mCRC, ORR, WT
45  2016 Meta-analysis comparing the efficacy of anti-EGFR monoclonal antibody therapy between KRAS G13D and other KRAS mutant metastatic colorectal cancer tumours. CI, mAbs, mCRC, OS, PFS, RCTs, WT
46  2016 Radiographic patterns and survival of patients with early and late brain metastases in EGFR wild type and mutant non small cell lung cancer. BM, OS, WT
47  2015 Cadmium toxicity to Microcystis aeruginosa PCC 7806 and its microcystin-lacking mutant. MC, polyP, TP
48  2015 Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors. AD, ERalpha, IHC, NSCLC, RTK, WT
49  2015 High-Throughput Mutation Profiling Changes before and 3 Weeks after Chemotherapy in Newly Diagnosed Breast Cancer Patients. WT
50  2015 Identification of altered metabolic pathways of gamma-irradiated rice mutant via network-based transcriptome analysis. DEGs
51  2015 Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism. 2-HG, WT
52  2015 Modulation of conidia production and expression of the gene bbrgs1 from Beauveria bassiana by oxygen pulses and light. WT
53  2015 Transcriptomic analysis of differentially expressed genes in an orange-pericarp mutant and wild type in pummelo (Citrus grandis). DEGs, GO, HPLC, qRT-PCR, WT
54  2015 [Quality evaluation and clinical applicability of pyrosequencing assay kit for detecting hepatitis B virus resistance]. WT
55  2014 CK2 phosphorylates and inhibits TAp73 tumor suppressor function to promote expression of cancer stem cell genes and phenotype in head and neck cancer. CSC, HNSCC, SP
56  2014 Dimerization, oligomerization, and aggregation of human amyotrophic lateral sclerosis copper/zinc superoxide dismutase 1 protein mutant forms in live cells. SOD1
57  2014 Recent advances in transthyretin amyloidosis therapy. ATTR, FAP, GI, LT, TTR, WT
58  2014 Structural perspectives of an engineered beta-1,4-xylanase with enhanced thermostability. GH10, WT
59  2014 Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling. ---
60  2014 The viral E8^E2C repressor limits productive replication of human papillomavirus 16. HPV-16, WT
61  2013 A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells. ChIP, WT
62  2013 An analysis of the treatment effect of panitumumab on overall survival from a phase 3, randomized, controlled, multicenter trial (20020408) in patients with chemotherapy refractory metastatic colorectal cancer. BSC, WT
63  2013 Computational analysis of KRAS mutations: implications for different effects on the KRAS p.G12D and p.G13D mutations. mCRC, MD, PMF, RMSD, WT
64  2013 Construction and expression of hepatitis B surface antigen escape variants within the "a" determinant by site directed mutagenesis. HBsAg, mAbs, WT
65  2013 HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma. EGFR, ERK, HNSCCs, Hsp90, STAT3, WT
66  2013 Ionizing radiation-induced gene expression changes in TP53 proficient and deficient glioblastoma cell lines. GBM, WT
67  2013 Mice expressing the ADNFLE valine 287 leucine mutation of the Beta2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function. ADNFLE, HT, nAChR, WT
68  2013 Similar dose-dependence of motor neuron cell death caused by wild type human TDP-43 and mutants with ALS-associated amino acid substitutions. hTDP-43, UBIs, WT
69  2013 Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells. EGFR, NSCLC, TKI, WT
70  2013 The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics. CRC, EGF, ERK, WT
71  2012 Activating mutations in beta-catenin in colon cancer cells alter their interaction with macrophages; the role of snail. dnTCF4, WT
72  2012 Differing von hippel lindau genotype in paired primary and metastatic tumors in patients with clear cell renal cell carcinoma. ccRCC, VHL, WT
73  2012 Evidence of the cost of the production of microcystins by Microcystis aeruginosa under differing light and nitrate environmental conditions. ---
74  2012 First-line panitumumab plus irinotecan/5-fluorouracil/leucovorin treatment in patients with metastatic colorectal cancer. mCRC, WT
75  2012 Quantitative SNP genotyping by affinity capillary electrophoresis using PEG-oligodeoxyribonucleotide block copolymers with electroosmotic flow. PEG-b-ODN
76  2012 Role of Kras status in patients with metastatic colorectal cancer receiving first-line chemotherapy plus bevacizumab: a TTD group cooperative study. mCRC, OS, PFS, WT
77  2012 SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress. Nrf2, SHPS-1, SIRPalpha, WT
78  2012 Shutoff of BZLF1 gene expression is necessary for immortalization of primary B cells by Epstein-Barr virus. dmt, EBV, tmt
79  2011 A GROWTH ADVANTAGE FOR MICROCYSTIN PRODUCTION BY MICROCYSTIS PCC7806 UNDER HIGH LIGHT(1). ---
80  2011 Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma. Hsp90, MCL, WT
81  2011 Contribution of autophagic cell death to p53-dependent cell death in human glioblastoma cell line SF126. WT
82  2011 Oncogenic Kras promotes chemotherapy-induced growth factor shedding via ADAM17. CRC, WT
83  2011 Partial inactivation of Ankrd26 causes diabetes with enhanced insulin responsiveness of adipose tissue in mice. ANKRD26
84  2011 Repair pathways independent of the Fanconi anemia nuclear core complex play a predominant role in mitigating formaldehyde-induced DNA damage. DSBs, FA, HR, WT
85  2011 Signal regulatory protein alpha regulates the homeostasis of T lymphocytes in the spleen. SIRPalpha
86  2011 The efficacy and safety of panitumumab administered concomitantly with FOLFIRI or Irinotecan in second-line therapy for metastatic colorectal cancer: the secondary analysis from STEPP (Skin Toxicity Evaluation Protocol With Panitumumab) by KRAS status. EGFR, mCRC, ORR, PFS, WT
87  2011 The severe short stature in two siblings with a heterozygous IGF1 mutation is not caused by a dominant negative effect of the putative truncated protein. IGF1, WT
88  2011 TNF-alpha promotes c-REL/DeltaNp63alpha interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer. HNSCC
89  2011 Transcriptome profile analysis of flowering molecular processes of early flowering trifoliate orange mutant and the wild-type [Poncirus trifoliata (L.) Raf.] by massively parallel signature sequencing. MPSS, WT
90  2010 Discovery and comparative profiling of microRNAs in a sweet orange red-flesh mutant and its wild type. WT
91  2010 Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. EGFR, HR, mCRC, OS, PFS, WT
92  2010 Repair of aberrant splicing in growth hormone receptor by antisense oligonucleotides targeting the splice sites of a pseudoexon. ASO-5, ASOs, GHI, GHR, WT
93  2010 Replacement of the C-terminal tetrapeptide (314 PAPV 317 to 314 SSSM 317) in interferon regulatory factor-2 alters its N-terminal DNA-binding activity. EMSA, IRF2, WT
94  2010 Role of SIRPalpha in regulation of mucosal immunity in the intestine. DCs, IFN, LP, SIRPalpha
95  2009 An inducible cartilage oligomeric matrix protein mouse model recapitulates human pseudoachondroplasia phenotype. COMP, ECM, PSACH, WT
96  2009 Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer. HNSCC, NF-kappaB, TbetaR, TGF-beta
97  2009 Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. MPSS, WT
98  2009 Conformational change of Escherichia coli signal recognition particle Ffh is affected by the functionality of signal peptides of ribose-binding protein. WT
99  2009 In vitro effect of radiation, antibody to epidermal growth factor receptor and Docetaxel in human head and neck squamous carcinoma cells with mutant P53 and over-expressed EGFR. ---
100  2009 Influence of Slc11a1 (formerly Nramp1) on DSS-induced colitis in mice. DSS, NRAMP1, SLC11A1, WT