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Abbreviation : NE
Long Form : neutrophil elastase
No. Year Title Co-occurring Abbreviation
2020 Alpha-1 Antitrypsin-A Target for MicroRNA-Based Therapeutic Development for Cystic Fibrosis. A1AT, CF, CFTR
2020 Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients. CF, IgA, LAW, MMP-9, MPO, TIMP-1, UAW
2020 Bovine sperm samples induce different NET phenotypes in a NADPH oxidase-, PAD4- and Ca++-dependent process. MPO, NET, NOX, PAD4, PMN, PTX, SC, SCP, SN
2020 Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury. AILI, NAC
2020 Effect of Pressure-Controlled Ventilation-Volume Guaranteed on One-Lung Ventilation in Elderly Patients Undergoing Thoracotomy. ALI, Cdyn, OLV, PCV-VG, PIP, VCV
2020 Enhanced formation of neutrophil extracellular traps in Kawasaki disease. cfDNA, HC, KD, NETs
2020 Faecal neutrophil elastase-antiprotease balance reflects colitis severity. IBD
2020 Glycoprotein A as a biomarker of pulmonary infection and inflammation in children with cystic fibrosis. BAL, BWT, CF, CI, GlycA, OR
2020 Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. 39pep-alpha2-M, alpha 1-PI, alpha 2M, CatG, HNE, MNEI, PR3
10  2020 Human serum albumin nanoparticles as nanovector carriers for proteins: Application to the antibacterial proteins "neutrophil elastase" and "secretory leukocyte protease inhibitor". HSA, SLPI
11  2020 Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock. NETs
12  2020 MRP8/14 and neutrophil elastase for predicting treatment response and occurrence of flare in patients with juvenile idiopathic arthritis. MRP
13  2020 Neutrophil elastase from myeloid cells promotes TSC2-null tumor growth. LAM, MDSC
14  2020 Neutrophil elastase-mediated proteolysis of the tumor suppressor p200 CUX1 promotes cell proliferation and inhibits cell differentiation in APL. APL, CUX1
15  2020 Neutrophil proteases degrade autoepitopes of NET-associated proteins. NETs, RA, SLE
16  2020 NLS-RARalpha contributes to differentiation block and increased leukemogenic potential in vivo. APL, LVNC, NLS, PML
17  2020 Nuclear import of NLS- RARalpha is mediated by importin alpha/beta. AML, APL, NLS
18  2020 Severity of chronic obstructive pulmonary disease with 'exacerbator with emphysema phenotype' is associated with potential biomarkers. COPD, FKN, MMP-12
19  2020 Sputum and salivary protein biomarkers and point-of-care biosensors for the management of COPD. COPD, CRP, IL, MMP, POC, TNF-alpha
20  2020 The pro-tumor effect and the anti-tumor effect of neutrophils extracellular traps. MMP-9, NETs
21  2019 1,25-Dihydroxyvitamin D3 induces formation of neutrophil extracellular trap-like structures and modulates the transcription of genes whose products are neutrophil extracellular trap-associated proteins: A pilot study. IFN, MPO, NETs, PDA4
22  2019 A High-throughput Assay to Assess and Quantify Neutrophil Extracellular Trap Formation. ANCA, MPO, NETs, SLE
23  2019 A specialized method of sputum collection and processing for therapeutic interventions in cystic fibrosis. BAL, CF, PWCF, SS, TETRIS
24  2019 A specific proteinase 3 activity footprint in alpha1-antitrypsin deficiency. alpha1-AT, COPD, PR3
25  2019 Activated neutrophil carbamylates albumin via the release of myeloperoxidase and reactive oxygen species regardless of NETosis. MPO, NETs, PMA, RA, ROS
26  2019 Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung. alpha1-AT, BPD, COPD, ECM
27  2019 Activity-Based Near-Infrared Fluorogenic Probe for Enabling in Vitro and in Vivo Profiling of Neutrophil Elastase. ALI, NEP
28  2019 Advanced Glycated End Products Alter Neutrophil Effect on Regulation of CD4+ T Cell Differentiation Through Induction of Myeloperoxidase and Neutrophil Elastase Activities. AGEs, MPO, RAGE
29  2019 Aggregatibacter actinomycetemcomitans induces detachment and death of human gingival epithelial cells and fibroblasts via elastase release following leukotoxin-dependent neutrophil lysis. HGECs, HGFs
30  2019 Assessment of Cytokine Release against Oral Mucosal Cell Line Culture (TR146) Stimulated by Neutrophil Elastase Associated with Behcet's Disease. OMM, SLS
31  2019 Besnoitia besnoiti bradyzoite stages induce suicidal- and rapid vital-NETosis. PMN, SEM
32  2019 Blue and Long-Wave Ultraviolet Light Induce in vitro Neutrophil Extracellular Trap (NET) Formation. MPO, NET, NETs, ROS, SLE, UV-vis
33  2019 Candida albicans triggers NADPH oxidase-independent neutrophil extracellular traps through dectin-2. NET
34  2019 Cathepsin G cleaves and activates IL-36gamma and promotes the inflammation of psoriasis. CG, FL, NETs
35  2019 Chlorpyrifos Suppresses Neutrophil Extracellular Traps in Carp by Promoting Necroptosis and Inhibiting Respiratory Burst Caused by the PKC/MAPK Pathway. CPF, CYLD, DAG, MAPK3, MLKL, MPO, Nec-1, NETs, PKC, PMA, RIP1, RIP3, ROS
36  2019 CIRP Induces Neutrophil Reverse Transendothelial Migration in Sepsis. CIRP, CLP, i.t, JAM-C, RM, rmCIRP, rTEM
37  2019 Degradation of Extracellular DNA Significantly Ameliorates Necrotizing Enterocolitis Severity in Mice. cfDNA, GPx, MDA, MPO, NEC, NETs, TLR4
38  2019 Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression. ---
39  2019 Eucalyptol promotes lung repair in mice following cigarette smoke-induced emphysema. COPD, CS, IL-1beta, IL-6, KC, Lm, MDA, MMP-12, MPO, NF-kappaB, SOD, TGF-beta1, TIMP-1, TNF-alpha
40  2019 Evaluation of active neutrophil elastase in sputum of bronchiectasis and cystic fibrosis patients: A comparison among different techniques. BE, CF
41  2019 Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Breath Condensate in Patients with COPD and Their Relationships with Disease Severity and Acute Exacerbations. COPD, EBC, MMP-12, PBMCs, qRT-PCR, TIMP-4
42  2019 Heparin induces neutrophil elastase dependent vital and lytic NET formation. HIT, NETs, ROS
43  2019 Ibrutinib-based therapy impaired neutrophils microbicidal activity in patients with chronic lymphocytic leukemia during the early phases of treatment. BCR, BTK, CLL, FcgammaRs, MPO
44  2019 Increased formation of neutrophil extracellular traps is associated with gut leakage in patients with type 1 but not type 2 diabetes. ANCA, C5a, LPS, NETs, PAD4, PR3, T2D
45  2019 Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. AAT, NAFLD, NSPs, PR3
46  2019 Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism. IHC/IF, LFD, NASH, NE KO, SPT2, TG, WD, WD-WT, WT
47  2019 Marked infiltration of neutrophils at the upper palpebral conjunctiva in patients with chronic graft-versus-host disease. cGVHD, HPF, IC, MPO
48  2019 Markers of NETosis Do Not Predict Neonatal Early Onset Sepsis: A Pilot Study. cfDNA, CRP, IL-6, MPO, NETs
49  2019 Matrine reduces cigarette smoke-induced airway neutrophilic inflammation by enhancing neutrophil apoptosis. BALF, COPD, CS
50  2019 Methodological evaluation of gingival crevicular fluid volume and neutrophil elastase levels: sequential sampling, length of sampling time and two different sampling methods. GCF
51  2019 Nanosilver induces the formation of neutrophil extracellular traps in mouse neutrophil granulocytes. ERK, LDH, NETs, PMN, ROS
52  2019 NETosis is associated with the severity of aortic stenosis: Links with inflammation. AS, AVA, citH3, IL-6, MPO, NETs
53  2019 Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes. ---
54  2019 Neutrophil elastase as a biomarker for bacterial infection in COPD. COPD
55  2019 Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy. MyD88, PAR, VE-cadherin
56  2019 Neutrophil Elastase Damages the Pulmonary Endothelial Glycocalyx in Lipopolysaccharide-Induced Experimental Endotoxemia. G-CSFKO, LPS
57  2019 Neutrophil Elastase Inhibition Ameliorates Endotoxin-Induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx. G-CSF-KO, IL-6, LPS
58  2019 Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post-ischemia/reperfusion injury. BM, I/R
59  2019 Neutrophil elastase promotes Leishmania donovani infection via interferon-beta. ISP
60  2019 Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma. CBG, RCL
61  2019 Neutrophil Extracellular Traps Associate with Clinical Stages in Breast Cancer. NETs
62  2019 Neutrophil extracellular traps promote cadmium chloride-induced lung injury in mice. BALF, Cd, COPD, NETs, RA
63  2019 Overexpression of MTA1 inhibits the metastatic ability of ZR-75-30 cells in vitro by promoting MTA2 degradation. MTA
64  2019 PepN is a non-essential, cell wall-localized protein that contributes to neutrophil elastase-mediated killing of Streptococcus pneumoniae. CW, NSPs, PepN, Spn
65  2019 Peptidomimetic inhibitors targeting the membrane-binding site of the neutrophil proteinase 3. CG, mbPR3, PR3
66  2019 Personalised anti-inflammatory therapy for bronchiectasis and cystic fibrosis: selecting patients for controlled trials of neutrophil elastase inhibition. CF
67  2019 Pinniped- and Cetacean-Derived ETosis Contributes to Combating Emerging Apicomplexan Parasites (Toxoplasma gondii, Neospora caninum) Circulating in Marine Environments. ET, MPO, NOX, PMNs, ROS
68  2019 Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation. CatC, ICatC, NSPs, PR3
69  2019 Protein kinase D and Gbetagamma mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2. CS, PAR2, PKD
70  2019 Role of NOD1/NOD2 receptors in Fusobacterium nucleatum mediated NETosis. MPO, NETs, NOD1, PAD4, PMNs
71  2019 Salivary levels of MPO, MMP-8 and TIMP-1 are associated with gingival inflammation response patterns during experimental gingivitis. MMP, MPO, suPAR, TIMP
72  2019 Single dose escalation studies with inhaled POL6014, a potent novel selective reversible inhibitor of human neutrophil elastase, in healthy volunteers and subjects with cystic fibrosis. CF, PK
73  2019 Stem cell paracrine actions in tissue regeneration and potential therapeutic effect in human endometrium: a retrospective study. AS/EA
74  2019 Systemic levels of anti-PAD4 autoantibodies correlate with airway obstruction in cystic fibrosis. Ab, ACPAs, CF, HC, MPO, NETs, PAD4, RA, SLE
75  2019 The antagonistic effect of Se on the Pb-weakening formation of neutrophil extracellular traps in chicken neutrophils. ERK, MPO, NETs, PKC, PMA, Se
76  2019 The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis. BAL, CF, CT
77  2019 The effect of neutrophil serine proteases on human nasal epithelial cell barrier function. CBF, CG, ELISA, HNEC-ALI, IL-6, PE, PR3, TER, ZO-1
78  2019 Transforming Growth Factor-beta-Neutralizing Antibodies Improve Alveolarization in the Oxygen-Exposed Newborn Mouse Lung. TGF
79  2019 Treatment with DNases rescues hidden neutrophil elastase from aggregated NETs. aggNETs, NETs
80  2018 2-Chlorofatty acids: lipid mediators of neutrophil extracellular trap formation. 2-ClFA, HOCl, MPO, NETs
81  2018 3,4,5-Trihydroxycinnamic acid attenuates lipopolysaccharide (LPS)-induced acute lung injury via downregulating inflammatory molecules and upregulating HO-1/AMPK activation. ALI, AMPK, BALF, HO-1, IL-6, IL-8, iNOS, LPS, MCP-1, NF-kappaB, THC, TNF-alpha
82  2018 Adjuvant pretreatment with alum protects neonatal mice in sepsis through myeloid cell activation. alum, NETs
83  2018 Age is the work of art? Impact of neutrophil and organism age on neutrophil extracellular trap formation. PAD4
84  2018 Bovine neutrophils form extracellular traps in response to the gastrointestinal parasite Ostertagia ostertagi. MPO, NETs, OO, OO extract
85  2018 Chemical Tools for Targeted Amplification of Reactive Oxygen Species in Neutrophils. ABPs, FPR, NOX2, ROS
86  2018 Cigarette smoke extract enhances neutrophil elastase-induced IL-8 production via proteinase-activated receptor-2 upregulation in human bronchial epithelial cells. COPD, CSE, ERK, PAR2
87  2018 Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer. MPO, NETs
88  2018 Competitive neutrophil elastase inhibitory isoflavones from the roots of Flemingia philippinensis. ---
89  2018 Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases. CF, CLRs, KO
90  2018 Dipeptidyl Peptidase 1 Inhibitor AZD7986 Induces a Sustained, Exposure-Dependent Reduction in Neutrophil Elastase Activity in Healthy Subjects. COPD, DPP1, NSPs
91  2018 Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis. CF
92  2018 Entamoeba histolytica Trophozoites Induce a Rapid Non-classical NETosis Mechanism Independent of NOX2-Derived Reactive Oxygen Species and PAD4 Activity. mtDNA, NETs, PAD4, ROS
93  2018 Evidence for multiple modes of neutrophil serine protease recognition by the EAP family of Staphylococcal innate immune evasion proteins. NSPs
94  2018 Functional attribution of LdISP, an endogenous serine protease inhibitor from Leishmania donovani in promoting infection. ---
95  2018 Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. HFD, WT
96  2018 Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis. CoMTB, DMOG, Mtb, NETs, TB
97  2018 Inflammatory serum markers up to 5years after comprehensive periodontal therapy of aggressive and chronic periodontitis. CRP
98  2018 Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis. BALF, CF, CT, IL
99  2018 KB001-A, a novel anti-inflammatory, found to be safe and well-tolerated in cystic fibrosis patients infected with Pseudomonas aeruginosa. CF, PA
100  2018 MiR-146a Regulates Neutrophil Extracellular Trap Formation That Predicts Adverse Cardiovascular Events in Patients With Atrial Fibrillation. ACEs, AF