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Abbreviation : NEU1
Long Form : neuraminidase 1
No. Year Title Co-occurring Abbreviation
2020 Clinical and electrophysiological characteristics of a type 1 sialidosis patient with a novel deletion mutation in NEU1 gene. ---
2020 Conventional and Unconventional Therapeutic Strategies for Sialidosis Type I. PPCA
2020 Type I sialidosis, a normosomatic lysosomal disease, in the differential diagnosis of late-onset ataxia and myoclonus: An overview. LSDs
2019 Altered Cell Surface N-Glycosylation of Resting and Activated T Cells in Systemic Lupus Erythematosus. Gal-1, SLE, ST3GAL6, ST6GAL1
2019 Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. WNT
2019 MicroRNA-205 ameliorates lipid accumulation in non-alcoholic fatty liver disease through targeting NEU1. HFD, NAFLD, OA, PH
2019 Neu-medullocytes, sialidase-positive B cells in the thymus, express autoimmune regulator (AIRE). AIRE, MHC, NEU2, UEA-1
2019 Neuraminidase 1-mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection. BALF, ED, MUC1, PA, PAK
2018 A positive feedback loop between IL-1beta, LPS and NEU1 may promote atherosclerosis by enhancing a pro-inflammatory state in monocytes and macrophages. Sias
10  2018 Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice. HFD, IR
11  2018 Rhinovirus infections change DNA methylation and mRNA expression in children with asthma. BAT3, HRVI, RV-16
12  2018 Selective Inhibitors of Human Neuraminidase 1 (NEU1). DANA, NEU, NEU2
13  2018 Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice. APOE, BM, VLDL
14  2018 [Development of Enzyme Drugs Derived from Transgenic Silkworms to Treat Lysosomal Diseases]. Ctsa, ERT
15  2017 Galactosialidosis: historic aspects and overview of investigated and emerging treatment options. beta-Gal, PPCA
16  2017 Sialidosis Type 1 with a Novel Mutation in the Neuraminidase-1 (NEU1) Gene. ---
17  2016 Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis. IPF
18  2016 Neuraminidase 1 (NEU1) promotes proliferation and migration as a diagnostic and prognostic biomarker of hepatocellular carcinoma. HCC
19  2016 New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability. TM, TM1
20  2016 The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo. C9-BA-DANA, PPCA
21  2015 NEU1 Sialidase Regulates Membrane-tethered Mucin (MUC1) Ectodomain Adhesiveness for Pseudomonas aeruginosa and Decoy Receptor Release. ED, MUC1
22  2015 Neuraminidase-1 mediates skeletal muscle regeneration. ---
23  2014 Lysosomal multienzyme complex: pros and cons of working together. beta-Gal, PPCA
24  2013 Galactosialidosis: review and analysis of CTSA gene mutations. GS
25  2012 Novel mutations in the neuraminidase-1 (NEU1) gene in two patients of sialidosis in India. ---
26  2011 Where catabolism meets signalling: neuraminidase 1 as a modulator of cell receptors. ---
27  2010 Molecular mechanisms of pathogenesis in a glycosphingolipid and a glycoprotein storage disease. ---
28  2010 Muscle degeneration in neuraminidase 1-deficient mice results from infiltration of the muscle fibers by expanded connective tissue. ---
29  2009 Expression and molecular dynamics studies on effect of amino acid substitutions at Arg344 in human cathepsin A on the protein local conformation. CathA, GLB, MD
30  2009 Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization. PPCA
31  2009 Impact of beta-galactosidase mutations on the expression of the canine lysosomal multienzyme complex. PPGB
32  2009 Protective protein/cathepsin A rescues N-glycosylation defects in neuraminidase-1. PPCA
33  2009 Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients. ---
34  2006 Elastogenesis in cultured dermal fibroblasts from patients with lysosomal beta-galactosidase, protective protein/cathepsin A and neuraminidase-1 deficiencies. beta-Gal, EBP, PPCA