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Abbreviation : NMDARs
Long Form : N-methyl-D-aspartate receptors
No. Year Title Co-occurring Abbreviation
2022 Association between NMDAR antagonists, drug abuse and dependence: A disproportionality analysis from the WHO pharmacovigilance database. ---
2022 Carnosic Acid Attenuates AβOs-Induced Apoptosis and Synaptic Impairment via Regulating NMDAR2B and Its Downstream Cascades in SH-SY5Y Cells. AbetaOs, AD, BDNF, CA, CREB, ERK, NMDA, NMDAR2B, PSD-95, SYN
2022 Characterization in nonhuman primates of (R)-[18F]OF-Me-NB1 and (S)-[18F]OF-Me-NB1 for imaging the GluN2B subunits of the NMDA receptor. BPND, MA1
2022 Comprehensive metabolomic characterization of the hippocampus in a ketamine mouse model of schizophrenia. ---
2022 Copper ions, prion protein and Aβ modulate Ca levels in central nervous system myelin in an NMDA receptor-dependent manner. ---
2022 Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors. ---
2022 Development and characterization of functional antibodies targeting NMDA receptors. ---
2022 Development and Validation of [3H]OF-NB1 for Preclinical Assessment of GluN1/2B Candidate Drugs. PET, sigma1R
2022 Different modes of synaptic and extrasynaptic NMDA receptor alteration in the hippocampus of P301S tau transgenic mice. AD, SDS-FRL, SLM, SR
10  2022 Differential Effects of N-methyl-D-aspartate Receptors Activation in the Insular Cortex during Memory Formation and Updating of a Motivational Conflict Task. IC, MIA, MIA
11  2022 Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity. AMPAR
12  2022 Effect of altered gut microbiota on visceral hypersensitivity of postinfectious irritable bowel syndrome mice. 5-HT, IBS, PI-IBS, SCFAs
13  2022 Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice. EPSCs, MSNs, NAc, SNL
14  2022 Evaluation of (rac)-, (R)- and (S)-18F-OF-NB1 for imaging GluN2B subunit-containing N-methyl-D-aspartate receptors in non-human primates. BPND, MA1, sigma1Rs, TACs, VT
15  2022 Excitatory and inhibitory D-serine binding to the NMDA receptor. LBDs
16  2022 Folic Acid Ameliorates Synaptic Impairment following Cerebral Ischemia/Reperfusion Injury via Inhibiting Excessive Activation of NMDA Receptors. MCAO/R, OGD/R
17  2022 GluN3 subunit expression correlates with increased vulnerability of hippocampus and entorhinal cortex to neurodegeneration in a model of temporal lobe epilepsy. ASTA, MEA, TLE
18  2022 Homocysteine can aggravate depressive like behaviors in a middle cerebral artery occlusion/reperfusion rat model: a possible role for NMDARs-mediated synaptic alterations. HHcy, MCAO, PSD
19  2022 Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95. hSR, MAGUK, PLP, PSD-95
20  2022 Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors. iGluRs
21  2022 Inhibition of NMDA receptors through a membrane-to-channel path. MCI
22  2022 Insulin Diminishes Superoxide Increase in Cytosol and Mitochondria of Cultured Cortical Neurons Treated with Toxic Glutamate. DCD, Glu
23  2022 Knockdown of astrocytic Grin2a exacerbated sleep deprivation-induced cognitive impairments and elevation of amyloid-beta. SD
24  2022 Life extension factor klotho regulates behavioral responses to stress via modulation of GluN2B function in the nucleus accumbens. NAc
25  2022 Long-Term Dynamic Changes of NMDA Receptors Following an Excitotoxic Challenge. ---
26  2022 LRFN2 binding to NMDAR inhibits the progress of ESCC via regulating the Wnt/β-Catenin and NF-κB signaling pathway. LRFN2
27  2022 N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective. NMDA
28  2022 N-Methyl-D-Aspartate Receptors Mediate Synaptic Plasticity Impairment of Hippocampal Neurons Due to Arsenic Exposure. ---
29  2022 Naringenin Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia by Inhibiting Hippocampal Oxidative Stress and Inflammatory Response and Promoting N-Methyl-D-Aspartate Receptor Signaling Pathway. NR1, NR2B, PSD-95, Romo1, SYP, VaD
30  2022 NMDA and AMPA receptor physiology and role in visceral hypersensitivity: a review. AMPARs
31  2022 NMDA receptor antagonists engender neuroprotection against gp120-induced cognitive dysfunction in rats through modulation of PKR activation, oxidative stress, ER stress and IRE1α signal pathway. EPSCs, ER, HAND, HIV-1, PKR
32  2022 NMDA receptor antagonists reduce amyloid-β deposition by modulating calpain-1 signaling and autophagy, rescuing cognitive impairment in 5XFAD mice. AD, GSK-3beta, LAMP-1, LC3B-II, SBDP, ULK1
33  2022 NMDA receptor signaling induces the chemoresistance of temozolomide via upregulation of MGMT expression in glioblastoma cells. GBM, MEM, MGMT, NMDA, TMZ
34  2022 NMDA receptor-targeted enrichment of CaMKIIα improves fear memory. CaMKIIalpha, LTP
35  2022 Nutritional and Metabolic Factors, Ethanol and Cholesterol, Interact With Calcium-Dependent N-Methyl-D-Aspartate Receptor Inhibition by Tricyclic Antidepressants. ATL, CDD, CLO, DES, TCAs
36  2022 Opportunities for Precision Treatment of GRIN2A and GRIN2B Gain-of-Function Variants in Triheteromeric N-Methyl-D-Aspartate Receptors. ---
37  2022 Pathway-specific contribution of parvalbumin interneuron NMDARs to synaptic currents and thalamocortical feedforward inhibition. mPFC, PFC
38  2022 Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors. FLIPR, MDD
39  2022 Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations. PE-S
40  2022 Protein quality control of N-methyl-D-aspartate receptors. CNS, ER
41  2022 Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder. ---
42  2022 Recovery from the damage of cranial radiation modulated by memantine, an NMDA receptor antagonist combined with hyperbaric oxygen therapy. ---
43  2022 Relationship Between Replay-Associated Ripples and Hippocampal N-Methyl-D-Aspartate Receptors: Preliminary Evidence From a PET-MEG Study in Schizophrenia. MEG, PET
44  2022 Restored Fyn Levels in Huntington's Disease Contributes to Enhanced Synaptic GluN2B-Composed NMDA Receptors and CREB Activity. CREB, HD, PSD, SKF
45  2022 Role of N-methyl-d-aspartate receptors in anxiety disorder with thyroid lesions. AD, GAD, HAMA, HPT, MNG, PTC, TNs, TRH
46  2022 Roles of N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy. ---
47  2022 Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors. AD, S1P
48  2022 Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. ---
49  2022 Targeting D-Amino Acid Oxidase (DAAO) for the Treatment of Schizophrenia: Rationale and Current Status of Research. DAAO, FAD
50  2022 Targeting NMDA Receptor Complex in Management of Epilepsy. CNS
51  2022 Targeting NMDA Receptors at the Neurovascular Unit: Past and Future Treatments for Central Nervous System Diseases. CNS
52  2022 The Application of the Neuroprotective and Potential Antioxidant Effect of Ergotamine Mediated by Targeting N-Methyl-D-Aspartate Receptors. TEVC
53  2022 The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors. ---
54  2022 Tricyclic Antidepressant Structure-Related Alterations in Calcium-Dependent Inhibition and Open-Channel Block of NMDA Receptors. ATL, CLO, DES, TCAs, Vm
55  2022 Zelquistinel is an orally bioavailable novel NMDA receptor allosteric modulator that exhibits rapid and sustained antidepressant-like effects. CSD, FST, LTP, MDD, mPFC
56  2021 14-3-3 proteins promote synaptic localization of N-methyl d-aspartate receptors (NMDARs) in mouse hippocampal and cortical neurons. ---
57  2021 7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo. AChE
58  2021 A de novo GRIN1 Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology. ---
59  2021 Activation of D1/D5 receptors ameliorates decreased intrinsic excitability of hippocampal neurons induced by neonatal blockade of N-methyl-d-aspartate receptors. ---
60  2021 Acute D-Serine Co-Agonism of beta-Cell NMDA Receptors Potentiates Glucose-Stimulated Insulin Secretion and Excitatory beta-Cell Membrane Activity. GSIS
61  2021 Age-Dependent Contributions of NMDA Receptors and L-Type Calcium Channels to Long-Term Depression in the Piriform Cortex. LTCCs, LTD, PC
62  2021 Altered Visual Function in a Larval Zebrafish Knockout of Neurodevelopmental Risk Gene pdzk1. CRFR1, ERG, pdzk1-KO, PSD-95
63  2021 Astrocyte GluN2C NMDA receptors control basal synaptic strengths of hippocampal CA1 pyramidal neurons in the stratum radiatum. ---
64  2021 Astrocytic N-Methyl-D-Aspartate Receptors Protect the Hippocampal Neurons Against Amyloid-β142-Induced Synaptotoxicity by Regulating Nerve Growth Factor. AD, NGF
65  2021 Atypical opioid receptors: unconventional biology and therapeutic opportunities. GPCRs, NOP
66  2021 Behind the scenes: Are latent memories supported by calcium independent plasticity? ---
67  2021 Biophysical and synaptic properties of NMDA receptors in the lateral habenula. LHb
68  2021 Clinical and therapeutic significance of genetic variation in the GRIN gene family encoding NMDARs. ID
69  2021 Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation. ATD, smFRET
70  2021 Cornel Iridoid Glycoside Suppresses Hyperactivity Phenotype in rTg4510 Mice through Reducing Tau Pathology and Improving Synaptic Dysfunction. AD, AMPAR, CIG
71  2021 Correlated conformational dynamics of the human GluN1-GluN2A type N-methyl-D-aspartate (NMDA) receptor. ATD, LBD, NMDA, PCA
72  2021 CPP impairs contextual learning at concentrations below those that block pyramidal neuron NMDARs and LTP in the CA1 region of the hippocampus. LTP
73  2021 D-Serine produces antidepressant-like effects in mice through suppression of BDNF signaling pathway and regulation of synaptic adaptations in the nucleus accumbens. BDNF, CSDS, FST, HPLC, LTD, NAc, TST
74  2021 Developmental plasticity of NMDA receptors at the calyx of Held synapse. ---
75  2021 Developmental regulation and lateralization of N-methyl-d-aspartate (NMDA) receptors in the rat hippocampus. CNS, IHC, NMDA, OD
76  2021 Diazepam Monotherapy or Diazepam-Ketamine Dual Therapy at Different Time Points Terminates Seizures and Reduces Mortality in a Status Epilepticus Animal Model. GABAARs, SE
77  2021 Differential expression of GluN2 NMDA receptor subunits in the dorsal horn of male and female rats. ---
78  2021 Differential expression of glutamatergic receptor subunits in the hippocampus in carioca high- and low-conditioned freezing rats. AMPARs, CHF, CLF, PSD-95
79  2021 Discovery of Novel and Potent N-Methyl-d-aspartate Receptor Positive Allosteric Modulators with Antidepressant-like Activity in Rodent Models. MDDs, PAMs
80  2021 Disrupting phosphorylation of Tyr-1070 at GluN2B selectively produces resilience to depression-like behaviors. CRS, MDD, mPFC
81  2021 Donepezil attenuates the development of morphine tolerance in rats with cancer-induced bone pain: The role of cortical N-methyl-D-aspartate receptors. CIBP, NR1
82  2021 Donepezil prevents morphine tolerance by regulating N-methyl-d-aspartate receptor, protein kinase C and CaM-dependent kinase II expression in rats. CaMKII, PAG, PKC
83  2021 Drugs Based on NMDAR Hypofunction Hypothesis in Schizophrenia. ---
84  2021 Early Life Febrile Seizures Impair Hippocampal Synaptic Plasticity in Young Rats. FSs, LTP
85  2021 Exercise-induced gene expression changes in skeletal muscle of old mice. AChRs, NMJs
86  2021 Flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of AMPARs in a male rat model of schizophrenia. AMPARs, CaMKII, CREB, LTP
87  2021 Forebrain expression of serine racemase during postnatal development. ASD, mPFC, NDDs, SR, SZ
88  2021 From Menopause to Neurodegeneration-Molecular Basis and Potential Therapy. AD, IGF-1
89  2021 GluN3A NMDA receptor subunits: more enigmatic than ever? ---
90  2021 Glutamate receptor, ionotropic, N‑methyl D‑aspartate‑associated protein 1 promotes colorectal cancer cell proliferation and metastasis, and is negatively regulated by miR‑296‑3p. CRC, miR
91  2021 GRIN2A Variants Associated With Idiopathic Generalized Epilepsies. ---
92  2021 Icaritin Alleviates Glutamate-Induced Neuronal Damage by Inactivating GluN2B-Containing NMDARs Through the ERK/DAPK1 Pathway. ICT, LDH
93  2021 Impaired Potentiation of Theta Oscillations During a Visual Cortical Plasticity Paradigm in Individuals With Schizophrenia. EEG, LTP, VEPs, VHFS
94  2021 Inhibiting ventral hippocampal NMDA receptors and Arc increases energy intake in male rats. Arc, vHC
95  2021 Inhibition of CAMK II modulates water permeability by reducing AQP4 expression in astrocytes after oxygen-glucose deprivation. AQP4, CaMKII, OGD
96  2021 Insulin Receptors and Intracellular Ca 2+ Form a Double-Negative Regulatory Feedback Loop Controlling Insulin Sensitivity. AD, ATP, IR
97  2021 Interplay between NMDA receptor dynamics and the synaptic proteasome. GluN2B-NMDARs
98  2021 Involvement of N-Methyl-D-Aspartate Receptors in the Anticonvulsive Effects of Licofelone on Pentylenetetrazole-Induced Clonic Seizure in Mice. i.p, NO, PTZ
99  2021 Isoliquiritigenin Alleviates Semen Strychni-Induced Neurotoxicity by Restoring the Metabolic Pathway of Neurotransmitters in Rats. 5-HT, COMT, DA, MAO
100  2021 Knockdown of astrocytic Grin2a aggravates β-amyloid-induced memory and cognitive deficits through regulating nerve growth factor. AAV, AD, NGF