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Abbreviation : OA
Long Form : okadaic acid
No. Year Title Co-occurring Abbreviation
2019 1-(2',5'-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of alpha7 Nicotinic Receptors with Analgesic and Neuroprotective Activity. AD, CFA, PAMs
2019 ABC Transporters in Prorocentrum lima and Their Expression Under Different Environmental Conditions Including Okadaic Acid Production. ---
2019 Alteration of O-GlcNAcylation affects assembly and axonal transport of neurofilament via phosphorylation. Don, FRAP, NAG-Ae, NFs
2019 AT2R Activation Prevents Microglia Pro-inflammatory Activation in a NOX-Dependent Manner: Inhibition of PKC Activation and p47phox Phosphorylation by PP2A. AD, Ang II, AT2R, NOX, p47KO, PD, PKC, PMA, PP2A, ROS
2019 Characterization of scallop midgut gland certified reference material for quantification of diarrhetic shellfish toxins. DTX-1
2019 Cholinergic Differentiation of Human Neuroblastoma SH-SY5Y Cell Line and Its Potential Use as an In vitro Model for Alzheimer's Disease Studies. AChE, AD, ChAT, RA
2019 Combined effects of okadaic acid and pectenotoxin-2, 13-desmethylspirolide C or yessotoxin in human intestinal Caco-2 cells. PTX-2, YTX
2019 Complement C3a receptor antagonist attenuates tau hyperphosphorylation via glycogen synthase kinase 3beta signaling pathways. AD, Cdk5, GSK3beta, PP2Ac
2019 Contamination status of lipophilic marine toxins in shellfish samples from the Bohai Sea, China. 13-desMeC, DTX-1, GYM, homo-YTX, PTX-2, YTX
10  2019 Detection of okadaic acid (OA) and tetrodotoxin (TTX) simultaneously in seafood samples using colloidal gold immunoassay. TTX, vLOD
11  2019 Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts. DTXs, PTXs
12  2019 Distribution, partitioning, and seasonal variation of lipophilic marine algal toxins in aquatic environments of a typical semi-closed mariculture bay. DP, DTX-1, DTX-2, GYM, LMATs, PP, PTX-2, PTX11, PTX2SA
13  2019 EMT is the major target for okadaic acid-suppressed the development of neural crest cells in chick embryo. Cad6B, DSP, NCCs
14  2019 Galangin decreases p‑tau, Abeta42 and beta‑secretase levels, and suppresses autophagy in okadaic acid‑induced PC12 cells via an Akt/GSK3beta/mTOR signaling‑dependent mechanism. AD
15  2019 Human neuroblastoma SH-SY5Y cells treated with okadaic acid express phosphorylated high molecular weight tau-immunoreactive protein species. AD, HMW-TIPs, SDS
16  2019 Impacts of the toxic benthic dinoflagellate Prorocentrum lima on the brown mussel Perna perna: Shell-valve closure response, immunology, and histopathology. RLOs
17  2019 LC-MS/MS Analysis of the Emerging Toxin Pinnatoxin-G and High Levels of Esterified OA Group Toxins in Galician Commercial Mussels. AZA-2, DTX-2, PnTX-G, PTX-2
18  2019 Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. WT
19  2019 Morphology and Phylogenetics of Benthic Prorocentrum Species (Dinophyceae) from Tropical Northwestern Australia. DTX
20  2019 Neuroprotective activity of isoquinoline alkaloids from of Chilean Amaryllidaceae plants against oxidative stress-induced cytotoxicity on human neuroblastoma SH-SY5Y cells and mouse hippocampal slice culture. AChE, GC/MS, OGD/R, R/O
21  2019 Novel Insights on the Toxicity of Phycotoxins on the Gut through the Targeting of Enteric Glial Cells. AZA1, EGCs, HCA, PLTX, PTX-2, YTX
22  2019 Okadaic acid (OA): Toxicity, detection and detoxification. ---
23  2019 Okadaic acid activates Wnt/beta-catenin-signaling in human HepaRG cells. DSP
24  2019 Peroxiredoxin II negatively regulates BMP2-induced osteoblast differentiation and bone formation via PP2A Calpha-mediated Smad1/5/9 dephosphorylation. ALP, BMP2, KO, LPS, muCT, PP2A Calpha, PrxII, WT
25  2019 Phosphorene-gold nanocomposite based microfluidic aptasensor for the detection of okadaic acid. SPCE
26  2019 Portable Multiplex Immunochromatographic Assay for Quantitation of Two Typical Algae Toxins Based on Dual-Color Fluorescence Microspheres. FMS, ICA, MC-LR
27  2019 Prevalence of phycotoxin contamination in shellfish from the Northern Bering Sea and the Chukchi Sea. dcNEO, dcSTX, DTX-2, GTXs, PTX-1, STX, YTX
28  2019 Recyclable magnetic covalent organic framework for the extraction of marine biotoxins. COFs, DTX-1
29  2019 Review of DSP Toxicity in Ireland: Long-Term Trend Impacts, Biodiversity and Toxin Profiles from a Monitoring Perspective. DSP, DTX-1, DTX-2, PTXs
30  2019 Role of protein phosphatase 2A in PTTH-stimulated prothoracic glands of the silkworm, Bombyx mori. 4E-BP, ERK, PGs, PLC, PP2A, PP2Ac, PTTH, ROS
31  2019 Simple Diffusion as the Mechanism of Okadaic Acid Uptake by the Mussel Digestive Gland. DSP
32  2019 The marine biotoxin okadaic acid affects intestinal tight junction proteins in human intestinal cells. TJPs, ZO
33  2019 Ultrastable nitrogen-doped carbon nanotube encapsulated cobalt nanoparticles for magnetic solid-phase extraction of okadaic acid from aquatic samples. LOD, LOQ, MSPE, N-CNTCs
34  2018 A Dual Functional Cardiomyocyte-based Hybrid-biosensor for the Detection of Diarrhetic Shellfish Poisoning and Paralytic Shellfish Poisoning Toxins. DSP, EFP, PSP, STX
35  2018 A magnetic beads-based portable flow cytometry immunosensor for in-situ detection of marine biotoxin. FCM, LOD, MBs, OA-MAb, R-PE
36  2018 Anatomical Distribution of Diarrhetic Shellfish Toxins (DSTs) in the Japanese Scallop Patinopecten yessoensis and Individual Variability in Scallops and Mytilus edulis Mussels: Statistical Considerations. DSTs, DTX
37  2018 Cdc45/Mcm2-7/GINS complex down-regulation mediates S phase arrest in okadaic acid-induced cell damage. DSP
38  2018 Changes in potassium channel modulation may underlie afterhyperpolarization plasticity in oxytocin neurons during late pregnancy. AHPs, CK2, ImAHP, OT, PP, TBB
39  2018 Comparative toxicity of dinophysistoxin-1 and okadaic acid in mice. DTX-1
40  2018 Cornel Iridoid Glycoside Inhibits Tau Hyperphosphorylation via Regulating Cross-Talk Between GSK-3beta and PP2A Signaling. AD, CIG, GFX, GSK-3beta, PME-1, PP2A, PP2Ac
41  2018 Design, synthesis and evaluation of novel bivalent beta-carboline derivatives as multifunctional agents for the treatment of Alzheimer's disease. AD
42  2018 Detection of Dinophysis Species and Associated Okadaic Acid in Farmed Shellfish: a Two-year Study from The Western Mediterranean Area. DSP
43  2018 Detoxification- and Immune-Related Transcriptomic Analysis of Gills from Bay Scallops (Argopectenirradians) in Response to Algal Toxin Okadaic Acid. DEGs
44  2018 Diel Variations in Cell Abundance and Trophic Transfer of Diarrheic Toxins during a Massive Dinophysis Bloom in Southern Brazil. ---
45  2018 Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid. AD, NFTs, NMDA, WM
46  2018 Dinophysis acuta in Scottish Coastal Waters and Its Influence on Diarrhetic Shellfish Toxin Profiles. DTX-1, DTX-2
47  2018 Does the phycotoxin Okadaic acid cause oxidative stress damages and histological alterations to seabream (Sparus aurata)? DSP
48  2018 Effect of Suspended Particulate Matter on the Accumulation of Dissolved Diarrhetic Shellfish Toxins by Mussels (Mytilus galloprovincialis) under Laboratory Conditions. DST, DTX-1, SPATT, SPM
49  2018 First identification of a C9-diol-ester of okadaic acid in Dinophysis acuta from Galician Rias Baixas (NW Spain). ---
50  2018 First Report of Okadaic Acid and Pectenotoxins in Individual Cells of Dinophysis and in Scallops Argopecten purpuratus from Peru. DSP, HAB, PTXs
51  2018 Interannual variability in Dinophysis spp. abundance and toxin accumulation in farmed mussels (Perna perna) in a subtropical estuary. DSP, MBA
52  2018 Interlaboratory comparison of liquid chromatography-tandem mass spectrometry quantification of diarrhetic shellfish toxins in scallop midgut glands. DTX-1, ILC
53  2018 Lipophilic marine biotoxins SERS sensing in solutions and in mussel tissue. DSP, DTX-1, DTX-2, YTX
54  2018 Long Noncoding RNA EBF3-AS Promotes Neuron Apoptosis in Alzheimer's Disease. AD, lncRNAs
55  2018 Molecular Dynamics and Quantum Chemical Approach for the Estimation of an Intramolecular Hydrogen Bond Strength in Okadaic Acid. ---
56  2018 Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3beta pathway in SH-SY5Y cells. ---
57  2018 Occurrence and distribution of marine natural organic pollutants: Lipophilic marine algal toxins in the Yellow Sea and the Bohai Sea, China. DTX-1, GYM, LMATs, PTX-2, SPM
58  2018 Protein kinase CK2 activation is required for transforming growth factor beta-induced epithelial-mesenchymal transition. EMT, TGF-beta, TGFBR
59  2018 Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells. cyt c, HCC, NO, PP2A-C, XIAP
60  2018 Quercetin inhibits okadaic acid-induced tau protein hyperphosphorylation through the Ca2+‑calpain‑p25‑CDK5 pathway in HT22 cells. AD, Cdk5, Que
61  2018 Self-assembled monolayer-based immunoassays for okadaic acid detection in seawater as monitoring tools. DSP
62  2018 Senkyunolide A protects neural cells against corticosterone-induced apoptosis by modulating protein phosphatase 2A and alpha-synuclein signaling. CORT, SenA, SPH
63  2018 Single Ethanol Withdrawal Regulates Extrasynaptic delta-GABAA Receptors Via PKCdelta Activation. GABAARs, PDBu, PKC
64  2018 Spatial and seasonal variation of diarrheic shellfish poisoning (DSP) toxins in bivalve mollusks from some coastal regions of Vietnam and assessment of potential health risks. DSP
65  2018 Toxic Action Reevaluation of Okadaic Acid, Dinophysistoxin-1 and Dinophysistoxin-2: Toxicity Equivalency Factors Based on the Oral Toxicity Study. DSP, DTX-1, DTX-2, LD50, PP2A, TEFs, TEM
66  2018 Toxin Profiles of Okadaic Acid Analogues and Other Lipophilic Toxins in Dinophysis from Japanese Coastal Waters. DTX, PTXs
67  2018 Variability and profiles of lipophilic toxins in bivalves from Great Britain during five and a half years of monitoring: Okadaic acid, dinophysis toxins and pectenotoxins. DTX-1, DTX-2, LCMS/MS, LTs, PTX-2
68  2018 Whole genome mRNA transcriptomics analysis reveals different modes of action of the diarrheic shellfish poisons okadaic acid and dinophysis toxin-1 versus azaspiracid-1 in Caco-2 cells. AZA1, DTX-1, ER, UPR
69  2017 Dental pulp stem cells promote regeneration of damaged neuron cells on the cellular model of Alzheimer's disease. AD, hDPSCs
70  2017 Detection of okadaic acid (OA) using ELISA and colloidal gold immunoassay based on monoclonal antibody. DSP, ic-ELISA, LOD
71  2017 Effects of algal toxin okadaic acid on the non-specific immune and antioxidant response of bay scallop (Argopecten irradians). ACP, ALP, DSP, SOD
72  2017 Embryotoxic effects of dissolved okadaic acid on the development of Longfin yellowtail Seriola rivoliana. BMP, HABs, PCNA
73  2017 Exposure of okadaic acid alters the angiogenesis in developing chick embryos. CAM, DSP, YSM
74  2017 Hyperglycemia triggers HIPK2 protein degradation. CL-A, HG, HIF-1, HIPK2, PP2A, Ser46
75  2017 Invitro bioaccessibility of the marine biotoxins okadaic acid, dinophysistoxin-2 and their 7-O-acyl fatty acid ester derivatives in raw and steamed shellfish. ---
76  2017 Label-free okadaic acid detection using growth of gold nanoparticles in sensor gaps as a conductive tag. ---
77  2017 Limaol: A Polyketide from the Benthic Marine Dinoflagellate Prorocentrum lima. ---
78  2017 Lipophilic marine toxins discovered in the Bohai Sea using high performance liquid chromatography coupled with tandem mass spectrometry. AZA1, desMeC, DTX-1, GYM, HG, HLD, HPLC, LS, LZ, PTX-2, QHD, YTX
79  2017 Metabolism of okadaic acid by NADPH-dependent enzymes present in human or rat liver S9 fractions results in different toxic effects. ---
80  2017 Occurrence of marine algal toxins in oyster and phytoplankton samples in Daya Bay, South China Sea. DA, DTX-1, DYB, GYM, homoYTX, PTX
81  2017 Passive immunization targeting the N-terminal region of phosphorylated tau (residues 68-71) improves spatial memory in okadaic acid induced tauopathy model rats. AD, NFT
82  2017 Phospho-specific antibodies targeting the amino terminus of the human dopamine transporter. AMPH, DAT, PMA, Ser
83  2017 Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice. GABAAR, LORR, LTWR, PRIP-1, PRIP-1 KO
84  2017 Protein phosphatase 2A regulation of markers of extracellular matrix remodelling in hepatocellular carcinoma cells: functional consequences for tumour invasion. MMP, PP
85  2017 Screening of lipophilic marine toxins in marine aquaculture environment using liquid chromatography-mass spectrometry. LMTs, PTX-2, SPM
86  2017 SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3beta activity in SH-SY5Y cells. AD, GSK-3beta
87  2017 Sublethal doses of dinophysistoxin-1 and okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences. DSP, DTX-1, MMP-9
88  2017 Toward Neuroproteomics in Biological Psychiatry: A Systems Approach Unravels Okadaic Acid-Induced Alterations in the Neuronal Phosphoproteome. PP
89  2017 [Inhibitory effect of magnesium cantharidate on human hepatoma SMMC-7721 cell proliferation by blocking MAPK signaling pathway]. ERK1, JNK1, MAPK, PP2A
90  2016 A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions. AD
91  2016 A novel sensitive cell-based Love Wave biosensor for marine toxin detection. DSP
92  2016 Absolute Quantification of Lipophilic Shellfish Toxins by Quantitative Nuclear Magnetic Resonance Using Removable Internal Reference Substance with SI Traceability. ---
93  2016 Accumulation, transformation and breakdown of DSP toxins from the toxic dinoflagellate Dinophysis acuta in blue mussels, Mytilus edulis. DTX, PTX
94  2016 Algal toxin profiles in Nigerian coastal waters (Gulf of Guinea) using passive sampling and liquid chromatography coupled to mass spectrometry. DTX-1, PTX-2
95  2016 Atorvastatin Alleviates Experimental Diabetic Cardiomyopathy by Regulating the GSK-3beta-PP2Ac-NF-kappaB Signaling Axis. ATOR, DCM, GSK, HG, PP2A, PP2Ac
96  2016 c-Jun N-terminal Kinase (JNK) induces phosphorylation of amyloid precursor protein (APP) at Thr668, in okadaic acid-induced neurodegeneration. AD, APP, JNK
97  2016 Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway. CA, PP1, PP2A, ZA
98  2016 Combined Effects of Lipophilic Phycotoxins (Okadaic Acid, Azapsiracid-1 and Yessotoxin) on Human Intestinal Cells Models. AZA1, HIEC, YTX
99  2016 Determination of multiple toxins in whelk and clam samples collected from the Chukchi and Bering seas. AZA, CI, DTX-1, GYM, PTX, STX, YTX
100  2016 Determination of the toxic variability of lipophilic biotoxins in marine bivalve and gastropod tissues treated with an industrial canning process. LMB, PTXs, YTXs