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Abbreviation : OA
Long Form : osteoactivin
No. Year Title Co-occurring Abbreviation
2019 miR-26b modulates OA induced BMSC osteogenesis through regulating GSK3beta/beta-catenin pathway. DEX, OP
2018 Osteoactivin inhibits dexamethasone-induced osteoporosis through up-regulating integrin beta1 and activate ERK pathway. DEX, OP
2018 Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases. HNSCC, MMP
2017 Exploratory study on the effect of osteoactivin on muscle regeneration in a rat volumetric muscle loss model. VML
2017 Identification of Novel Agents for the Treatment of Brain Metastases of Breast Cancer. BBB
2016 Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping. FRC, HRNF, MMPs, qPCR
2016 Macrophage-Associated Osteoactivin/GPNMB Mediates Mesenchymal Stem Cell Survival, Proliferation, and Migration Via a CD44-Dependent Mechanism. GPNMB, MSCs
2016 Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas. MAPKs, OSCC
2016 Prospects of osteoactivin in tissue regeneration. ---
10  2016 Transgenic Expression of Osteoactivin/gpnmb Enhances Bone Formation In Vivo and Osteoprogenitor Differentiation Ex Vivo. OA-Tg, WT
11  2015 Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin alphaVbeta3 and Inhibits Osteoclast Differentiation. CS-E, GAGs, HSPG
12  2015 The potential role of the glycoprotein osteoactivin/glycoprotein nonmetastatic melanoma protein B in pancreatic cancer. GPNMB
13  2014 GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity. GPNMB
14  2014 Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro. D2J
15  2014 Osteoactivin induces transdifferentiation of C2C12 myoblasts into osteoblasts. FAK
16  2014 Osteoactivin promotes osteoblast adhesion through HSPG and alphavbeta1 integrin. ALP, HSPGs, rOA
17  2012 Gpnmb/osteoactivin, an attractive target in cancer immunotherapy. mAbs
18  2012 Homeodomain transcription factors regulate BMP-2-induced osteoactivin transcription in osteoblasts. BMP-2
19  2012 Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice. TRAP, WT
20  2011 Comparison of bone morphogenetic protein-2 and osteoactivin for mesenchymal cell differentiation: effects of bolus and continuous administration. ALP, BMP-2, BMPs
21  2011 [Expression and mechanism of osteoactivin in the kidney of SD rats after acute cyclosporine A toxicity]. Col III, CsA, MMP-13, SCr
22  2010 ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties. ECD, GPNMB
23  2010 Functional roles of osteoactivin in normal and disease processes. ---
24  2010 Temporal and spatial expression of osteoactivin during fracture repair. PF
25  2009 Osteoactivin bioinformatic analysis: prediction of novel functions, structural features, and modes of action. ---
26  2008 Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity. ---
27  2008 Osteoactivin, an anabolic factor that regulates osteoblast differentiation and function. RA, TM
28  2007 Osteoactivin acts as downstream mediator of BMP-2 effects on osteoblast function. ---
29  2007 The role of osteoactivin-derived peptides in osteoblast differentiation. NCP, OA-D
30  2007 Transgenic expression of osteoactivin in the liver attenuates hepatic fibrosis in rats. CDAA, OA-Tg, WT
31  2003 Anti-osteoactivin antibody inhibits osteoblast differentiation and function in vitro. ---
32  2003 Identification and characterization of the genes encoding human and mouse osteoactivin. ---
33  2003 Osteoactivin expressed during cirrhosis development in rats fed a choline-deficient, L-amino acid-defined diet, accelerates motility of hepatoma cells. CDAA, HCC