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Abbreviation : OCLN
Long Form : occludin
No. Year Title Co-occurring Abbreviation
2021 Establishment of a novel probe-based RT-qPCR approach for detection and quantification of tight junctions reveals age-related changes in the gut barriers of broiler chickens. CLDN, TJs, ZO-1
2021 Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients. AR, Dsg3, TJs, TSLP
2020 Calcipotriol and iBRD9 reduce obesity in Nur77 knockout mice by regulating the gut microbiota, improving intestinal mucosal barrier function. Cldn3, IL-1beta, IL-6, TNF-alpha
2020 Clostridium perfringens beta2 toxin induced in vitro oxidative damage and its toxic assessment in porcine small intestinal epithelial cell lines. CLDN12, CPB2, DeltaPsim, IL-10, IL-8, LDH, ROS, TNF-alpha
2020 Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau. ADG, CLDN1, ZO-1
2020 Disruption of tight junctions contributes to hyposalivation of salivary glands in a mouse model of type 2 diabetes. CLDN1, Cldn10, Cldn3, Cldn4, PGs, SMGs, TJ, ZO-1
2020 Effect of blood pressure on early neurological deterioration of acute ischemic stroke patients with intravenous rt-PA thrombolysis may be mediated through oxidative stress induced blood-brain barrier disruption and AQP4 upregulation. AQP4, BP, END, MDA, MMP-9, ROC, SBP, SOD
2020 Effect of Perfluorooctanoic Acid on the Epigenetic and Tight Junction Genes of the Mouse Intestine. CLDN, PFOA, TJ, Tjp
2020 Effects of an F18 enterotoxigenic Escherichia coli challenge on growth performance, immunological status, and gastrointestinal structure of weaned pigs and the potential protective effect of direct-fed microbial blends. ADFI, ADG, BW, CFU, DFM, dpi, ETEC, IL-8, PC, TNF-alpha, ZO-1
10  2020 Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts. Ca, CLDN1, CLDN4, KLK4
11  2020 Effects of supplementation with beta-carotene on the growth performance and intestinal mucosal barriers in layer-type cockerels. CCR9, IgA, MUC2, pIgR, RA, RARalpha, sIgA, ZO-1, ZO-2
12  2020 Expression of Tight Junction Proteins According to Functional Dyspepsia Subtype and Sex. CLDN, FD, TJPs
13  2020 Gallic acid affects intestinal-epithelial-cell integrity and selected amino-acid uptake in porcine in vitro and ex vivo permeability models. CAT-1, CLDN1, EAAT3, GA, L-Arg, l-Glut, l-Lys, l-Meth, TEER, ZO-1
14  2020 Hepatitis C virus infection and tight junction proteins: The ties that bind. CLDN1, EGFR, HCC, HCV, HSPG, LDLR, NPC1L1, SR-BI, TJ
15  2020 High dose of baicalin or baicalein can reduce tight junction integrity by partly targeting the first PDZ domain of zonula occludens-1 (ZO-1). CLDs, EMT, MDCK, PDZ1, PSD-95, TGF-beta, TJ, ZO-1
16  2020 Influences of dietary starch structure on intestinal morphology, barrier functions, and epithelium apoptosis in weaned pigs. Bcl-2, BW, MA, SA, ZO-1
17  2020 Interdependence between Chromogranin-A, Alternatively Activated Macrophages, Tight Junction Proteins and the Epithelial Functions. A Human and In-Vivo/In-Vitro Descriptive Study. CHGA, CLDN1, DSS, IECs, IL, TJ, UC, ZO-1
18  2020 Intestinal Barrier Integrity in Heat-Stressed Modern Broilers and Their Ancestor Wild Jungle Fowl. CALPR, CDH1, FITC-d, GJA1, JF, PATJ, VIL1
19  2020 In Vivo Transplantation of Human Intestinal Organoids Enhances Select Tight Junction Gene Expression. CLDN15, CLDN3, HIO, TESI, tHIOs
20  2020 Lactobacillus casei LC01 Regulates Intestinal Epithelial Permeability through miR-144 Targeting of OCLN and ZO1. IBS-D, IECs
21  2020 Low molecular weight heparin (nadroparin) improves placental permeability in rats with gestational diabetes mellitus via reduction of tight junction factors. AGEs, EB, GDM, LMWH, RAGE, TJ, VEGF
22  2020 Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells. CLDN8, HMCs-1, IBD, IECs, MCs
23  2020 Non-invasive Assessment of Fecal Stress Biomarkers in Hunting Dogs During Exercise and at Rest. CALP, FCMs, GI, HO-1, IgA, IL, PAR-2, TAC, TNF-alpha
24  2020 Occludin protects secretory cells from ER stress by facilitating SNARE-dependent apical protein exocytosis. ER, MPCs, TJs
25  2020 Occludin, caveolin-1, and Alix form a multi-protein complex and regulate HIV-1 infection of brain pericytes. BBB, Cav-1
26  2020 Occludin-binding single-chain variable fragment and antigen-binding fragment antibodies prevent hepatitis C virus infection. HCV, mAbs, scFv
27  2020 Protected Blend of Organic Acids and Essential Oils Improves Growth Performance, Nutrient Digestibility, and Intestinal Health of Broiler Chickens Undergoing an Intestinal Challenge. AGP, BWG, CLDN1, FCR, FITC-d, IDE, ISI, MUC2
28  2020 Saccharomyces cerevisiae Fermentation Product Did Not Attenuate Clinical Signs, but Psyllium Husk Has Protective Effects in a Murine Dextran Sulfate Sodium-Induced Colitis Model. CLDN, DAI, DSS, MLN, PH, SCFP
29  2020 Soluble Fiber and Insoluble Fiber Regulate Colonic Microbiota and Barrier Function in a Piglet Model. CLDN1, IDF, MUC2, SCFA, SDF, sIgA, ZO-1
30  2020 Tannic acid prevents post-weaning diarrhea by improving intestinal barrier integrity and function in weaned piglets. DAO, TA, ZO-1, ZO-2
31  2020 Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease. AD, APOE, BBB, CAA, CLDN5
32  2020 The Characteristics of Intestinal-Barrier Damage in Rats With IgA Nephropathy. D-LA, DAO, IgAN, MUC2, NC, SD, ZO-1
33  2020 The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression. IECs, IGF2BP1
34  2020 Tree shrew bone marrow-derived mesenchymal stem cells express CD81, OCLN, and miR-122, facilitating the entire hepatitis C virus life cycle. BM-MSC, CD81, HCV, miR-122, VEGF
35  2019 A soluble and highly fermentable dietary fiber with carbohydrases improved gut barrier integrity markers and growth performance in F18 ETEC challenged pigs1. ETEC, IF, NC, PC, SF
36  2019 Bacillus amyloliquefaciens Ameliorates H2O2-Induced Oxidative Damage by Regulating Transporters, Tight Junctions, and Apoptosis Gene Expression in Cell Line IPEC-1. ASCT1, Bcl-2, GLUT2, LAT1
37  2019 Changes in the expression and distribution of junction and polarity proteins in the porcine endometrium during early pregnancy period. AJ, aPKC, Cdc42, CLDN1, PAR, TJ, ZO-1
38  2019 Characterization of monoclonal antibodies recognizing each extracellular loop domain of occludin. ELs, HCV, mAbs
39  2019 Construction of prognostic risk prediction model of oral squamous cell carcinoma based on co-methylated genes. CASD1, CENPV, DMGs, OSCC, SYTL2, TUB, WGCNA
40  2019 Corrigendum to: Cytoplasmic polyadenylation element binding protein 2 (CPEB2) is required for tight-junction assembly for establishment of porcine trophectoderm epithelium. CPEB, CPEB2, CXADR, TJ, TJP1
41  2019 Curcumin Alleviates IUGR Jejunum Damage by Increasing Antioxidant Capacity through Nrf2/Keap1 Pathway in Growing Pigs. bax, bcl2, caspase 3, GCLC, GCLM, HSP70, IFN-gamma, IL-2, IL-6, MDA, NBW, NQO1, Nrf2, SOD1, T-SOD, TNF-alpha
42  2019 Dietary supplementation with free methionine or methionine dipeptide mitigates intestinal oxidative stress induced by Eimeria spp. challenge in broiler chickens. BWG, CAT, CAT-1, CP, FCR, FI, IFNG, IL-2, PEPT1, PI, SOD, SOD1, TAC, TBARS, TLR5
43  2019 Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion. CLDN1, HCV, SR-BI
44  2019 Human-rat chimeric anti-occludin monoclonal antibodies inhibit hepatitis C virus infection. HCV, IgG4m, mAbs
45  2019 Oxyquinoline-Dependent Changes in Claudin-Encoding Genes Contribute to Impairment of the Barrier Function of the Trophoblast Monolayer. AMOTL1, HIF, TEER
46  2019 Role of the cytosolic domain of occludin in trafficking and hepatitis C virus infection. HCV, TGN, TJ
47  2019 Seizures Are Associated with Blood-Brain Barrier Disruption in a Piglet Model of Neonatal Hypoxic-Ischaemic Encephalopathy. aEEG, BBB, CLDN5, CNS, HI, HI, HIE, MMP-2, qPCR, VEGF, ZO-1
48  2019 Skin barrier damage after exposure to paraphenylenediamine. ACD, CLDN1, CLMP, FLG1, LOR, MAGI1, PPD
49  2019 Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. ---
50  2018 A lethal fungal pathogen directly alters tight junction proteins in the skin of a susceptible amphibian. Bd, bTJ, CLDN, TJ, TRIC, tTJ, ZO-1
51  2018 Chronic stress-associated visceral hyperalgesia correlates with severity of intestinal barrier dysfunction. WAS
52  2018 Comparison of Tight Junction Protein-Related Gene mRNA Expression Levels between Male and Female Gastroesophageal Reflux Disease Patients. CLDN1, CLDN4, ERD, GERD, NERD, NK1R, ZO
53  2018 Cytoplasmic polyadenylation element binding protein 2 (CPEB2) is required for tight-junction assembly for establishment of porcine trophectoderm epithelium. CPEB, CPEB2, CXADR, TJ, TJP1
54  2018 Diet supplementation with an organic acids-based formulation affects gut microbiota and expression of gut barrier genes in broilers. AV, CLDN1, CLDN5, IgA, MUC2, NFKB1, OA, OAAV, OABF, TLR2B, TLR4, VFA, ZO-1, ZO2
55  2018 Downregulation of occludin affects the proliferation, apoptosis and metastatic properties of human lung carcinoma. ---
56  2018 Effect of deoxynivalenol on apoptosis, barrier function, and expression levels of genes involved in nutrient transport, mitochondrial biogenesis and function in IPEC-J2 cells. ASCT2, CcOX, CLDN1, CS, cyt c, DON, GLUT2, IPEC-J2, mt polr, ND4, NRF, SGLT1, ZO-1
57  2018 Effect of interleukin-1β on occludin mRNA expression in the duodenal and colonic mucosa of dogs with inflammatory bowel disease. IBD, IL, RA
58  2018 Effects of 17beta-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model. AOM, CLDN4, DSS, ELISA, IBDs, MPO, MUC2, MUC4, ZO-1
59  2018 Exogenous carbohydrases added to a starter diet reduced markers of systemic immune activation and decreased Lactobacillus in weaned pigs1. CLDN3, CON, EB
60  2018 Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients. BBB, CLN-5, MRI, MS, PBMC, S1P1, TJ, ZO-1
61  2018 Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells. DXR, PI3K
62  2018 Infection with hepatitis C virus depends on TACSTD2, a regulator of claudin-1 and occludin highly downregulated in hepatocellular carcinoma. CLDN1, HCC, HCV, SR-B1, TACSTD2, TJ
63  2018 Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids. IBS, IFN-gamma, LGG, ZO-1
64  2018 miR-130a and miR-212 Disrupt the Intestinal Epithelial Barrier through Modulation of PPARgamma and Occludin Expression in Chronic Simian Immunodeficiency Virus-Infected Rhesus Macaques. miRNAs, PPARgamma
65  2018 Monoclonal Antibodies against Occludin Completely Prevented Hepatitis C Virus Infection in a Mouse Model. CLDN1, HCV, mAbs
66  2018 Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process. CD81, CLDN1, EGFR, HCV
67  2018 SNP rs688 within the low-density lipoprotein receptor (LDL-R) gene associates with HCV susceptibility. ACS, CLDN1, IDU, LDLR, MEU, MOSAIC, NPC1L1, SNPs, SR-1
68  2018 The role of tight junction proteins in ovarian follicular development and ovarian cancer. CGN, CLDN, TJ, TJP1
69  2017 A Novel Prebiotic Blend Product Prevents Irritable Bowel Syndrome in Mice by Improving Gut Microbiota and Modulating Immune Response. FOS, GOS, IBS, PB, PPAR
70  2017 Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission. APOE, CLDN1, CRISPR, HCV, LDLR, SDC1, TIM-1, VLDL
71  2017 Comprehensive molecular screening strategy of OCLN in band-like calcification with simplified gyration and polymicrogyria. BLC-PMG
72  2017 Downregulation of OCLN and GAS1 in clear cell renal cell carcinoma. ccRCC, GAS1, qPCR, SLC2A1
73  2017 Dual Functioned Pegylated Phospholipid Micelles Containing Cationic Antimicrobial Decapeptide for Treating Sepsis. DSPE, LPS, PEG, PLM
74  2017 Ectopic delivery of miR-200c diminishes hepatitis C virus infectivity through transcriptional and translational repression of Occludin. ---
75  2017 Effect of Jiaotai Pill () on intestinal damage in partially sleep deprived rats. LPS, OR, PSD
76  2017 Effects of dietary L-methionine supplementation on intestinal integrity and oxidative status in intrauterine growth-retarded weanling piglets. IUGR, MDA, NBW, VH
77  2017 Evidence that gene expression of ovarian follicular tight junction proteins is regulated in vivo and in vitro in cattle. CGN, DEX, DHT, EGF, FGF9, GC, TC, TJ, TJP1, TNF-alpha, VEGF-A
78  2017 Fusion expression of Occludin extracellular loops and an alpha-helical bundle: A new research model for tight junction. ECLs, HCV, TJs
79  2017 Increased cerebral expressions of MMPs, CLDN5, OCLN, ZO1 and AQPs are associated with brain edema following fatal heat stroke. CLDN5, CNRQ, ZO1
80  2017 Interferon Regulatory Factor 6 Promotes Keratinocyte Differentiation in Response to Porphyromonas gingivalis. Grhl3, IRF6, IVL, KRT13, OVOL1, RIPK4, TGM1
81  2017 MiR-144 Increases Intestinal Permeability in IBS-D Rats by Targeting OCLN and ZO1. ELISAs, HE, IBS-D, miRNAs
82  2017 Occludin as a functional marker of vascular endothelial cells on tube-forming activity. EPCs
83  2017 Occludin expression and regulation in small follicles of the layer and broiler breeder hen. EGF, RF
84  2017 Regulated Entry of Hepatitis C Virus into Hepatocytes. CD, CLDN1, EGFR, HCV, SR-BI, TGF-betaR
85  2016 Bone morphogenetic protein 15 may promote follicle selection in the hen. AMH, BMP15, FSHR, rhBMP15
86  2016 Circulating tight junction proteins mirror blood-brain barrier integrity in leukaemia central nervous system metastasis. CLDN5, CNS, CNSL, CSF, TJ
87  2016 Dietary spray-dried chicken plasma improves intestinal barrier function and modulates immune status in weaning piglets. CLDN1, GLP2, MUC2, SDCP, SDPP, sIgA, TFF3, TLR2, TNF-alpha, ZO-1, ZO-2
88  2016 Expanding the Host Range of Hepatitis C Virus through Viral Adaptation. HCV
89  2016 Expression of Tight Junction Proteins and Cadherin 17 in the Small Intestine of Young Goats Offered a Reduced N and/or Ca Diet. AJ, Ca, TJ
90  2016 Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. CLDN1, EMT, HCV, HCVpps, IRES
91  2016 Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo. HCV
92  2016 Occludin-Knockout Human Hepatic Huh7.5.1-8-Derived Cells Are Completely Resistant to Hepatitis C Virus Infection. CRISPR, HCV
93  2016 Overexpression of miR-429 impairs intestinal barrier function in diabetic mice by down-regulating occludin expression. DM, IECs, miRNAs, ZO-1
95  2016 Reduced Mucosa-associated Butyricicoccus Activity in Patients with Ulcerative Colitis Correlates with Aberrant Claudin-1 Expression. CLDN1, TJ, TJP1, TNF-alpha, UC
96  2016 Supplemental lipoic acid relieves post-weaning diarrhoea bydecreasing intestinal permeability in rats. LA, ZnO, ZO-1
97  2016 The E3 ubiquitin ligase MARCH3 controls the endothelial barrier. MARCH3
98  2015 A New Panel of Blood Biomarkers for the Diagnosis of Mild Traumatic Brain Injury/Concussion in Adults. MMP-9, mTBI, OI
99  2015 Analyses of Gingival Adhesion Molecules in Periodontitis: Theoretical In Silico, Comparative In Vivo, and Explanatory In Vitro Models. Dsc, Dsg, HNP-1
100  2015 Claudin-6 and Occludin Natural Variants Found in a Patient Highly Exposed but Not Infected with Hepatitis C Virus (HCV) Do Not Confer HCV Resistance In Vitro. CLDN6, HCV, HCVpp