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Abbreviation : OPIDN
Long Form : organophosphate-induced delayed neuropathy
No. Year Title Co-occurring Abbreviation
2021 Atg7 Knockout Alleviated the Axonal Injury of Neuro-2a Cells Induced by Tri-Ortho-Cresyl Phosphate. N2a, TOCP
2021 SARM1-mediated wallerian degeneration: A possible mechanism underlying organophosphorus-induced delayed neuropathy. NTE, OPs
2020 Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases. AD, ALS, HD, NDDs, PD
2020 Neuropathy target esterase (NTE/PNPLA6) and organophosphorus compound-induced delayed neurotoxicity (OPIDN). ALS, CNS, NTE, OP, PNS, SWS
2020 Organophosphate induced delayed neuropathy after an acute cholinergic crisis in self-poisoning. NCS
2020 The role of protein kinase C alpha in tri-ortho-cresyl phosphate-induced autophagy in human neuroblastoma SK-N-SH cells. NBR1, PKCalpha, TOCP, UPS
2019 Activation of PINK1-Parkin-dependent mitophagy in Tri-ortho-cresyl phosphate-treated Neuro2a cells. N2a, TOCP
2018 Activation of Neuregulin 1/ErbB Signaling Is Involved in the Development of TOCP-Induced Delayed Neuropathy. NTE, TOCP
2017 A Panel of Autoantibodies Against Neural Proteins as Peripheral Biomarker for Pesticide-Induced Neurotoxicity. CaMKII, GFAP, MAG, MAP-2, MBP, NFPs, OPICN, OPs, SNCA, tau
10  2017 L- and T-type calcium channel blockers protect against the inhibitory effects of mipafox on neurite outgrowth and plasticity-related proteins in SH-SY5Y cells. GAP-43, NTE, OP, VGCC
11  2017 Phenyl valerate esterase activity of human butyrylcholinesterase. BuChE, hBuChE, hBuChE, kcat, NTE, PVase
12  2017 TRPA1 channel mediates organophosphate-induced delayed neuropathy. OP, TOCP
13  2016 Assessment of neurotoxic effects of tri-cresyl phosphates (TCPs) and cresyl saligenin phosphate (CBDP) using a combination of in vitro techniques. AChE, NTE, OPs, TCPs, VGCC
14  2016 Biologic activity of cyclic and caged phosphates: a review. AChE, NTE, TOCP
15  2016 Disturbed phospholipid homeostasis in endoplasmic reticulum initiates tri-o-cresyl phosphate-induced delayed neurotoxicity. DAG, ER, GPC, LPC, LPE, LPS, NTE, PA, PC, PE, PG, PI, PMSF, SM, TOCP
16  2016 High concentration of trichlorfon (1mM) disrupts axonal cytoskeleton and decreases the expression of plasticity-related proteins in SH-SY5Y cells. NF200, NTE, OPs
17  2016 Neuropathy target esterase in mouse whole blood as a biomarker of exposure to neuropathic organophosphorus compounds. AChE, i.p, NTE, OP
18  2016 Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review. ACh, AChE, CNS, GABA, OP, OPICN, OPIED
19  2015 Apelin-13 Prevents the Delayed Neuropathy Induced by Tri-ortho-cresyl Phosphate Through Regulation the Autophagy Flux in Hens. LC3, TOCP
20  2015 In vitro study of the neuropathic potential of the organophosphorus compounds fenamiphos and profenofos: Comparison with mipafox and paraoxon. AChE, NTE, OP
21  2015 In vitro study of the neuropathic potential of the organophosphorus compounds trichlorfon and acephate. AChE, NTE, OPs
22  2015 Restricted diffusion in the splenium of the corpus callosum in organophosphate induced delayed neuropathy: case report and review of literatures. MRI
23  2014 Organophosphate-induced changes in the PKA regulatory function of Swiss Cheese/NTE lead to behavioral deficits and neurodegeneration. NTE, OPs, SWS, TOCP
24  2013 Activation of mitochondria-mediated apoptotic pathway in tri-ortho-cresyl phosphate-induced delayed neuropathy. TOCP
25  2013 Identification of differentially expressed proteins related to organophosphorus-induced delayed neuropathy in the brains of hens. Gln, Glu, GS, PMSF, TOCP
26  2013 Induction of autophagy by TOCP in differentiated human neuroblastoma cells lead to degradation of cytoskeletal components and inhibition of neurite outgrowth. 3-MA, NF-L, TOCP
27  2013 Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens. LC3, OP, TOCP
28  2012 Biochemical, histopathological and clinical evaluation of delayed effects caused by methamidophos isoforms and TOCP in hens: ameliorative effects using control of calcium homeostasis. AChE, NTE, TOCP
29  2012 Calcium-dependent neutral cysteine protease and organophosphate-induced delayed neuropathy. OPs
30  2012 Changes in beclin-1 and micro-calpain expression in tri-ortho-cresyl phosphate-induced delayed neuropathy. PMSF, TOCP
31  2012 Increased oxidative stress is associated with the development of organophosphate-induced delayed neuropathy. MCP
32  2012 Mechanisms for consideration for intervention in the development of organophosphorus-induced delayed neuropathy. NTE, OPs
33  2012 [Changes in autophagy-related protein levels in nervous tissues of hens with tri-ortho-cresyl phosphate-induced delayed neuropathy]. TOCP
34  2011 Comparative in vitro study of the inhibition of human and hen esterases by methamidophos enantiomers. AChE, LNTE, NTE, OECD, OPs
35  2011 Early differential cell death and survival mechanisms initiate and contribute to the development of OPIDN: a study of molecular, cellular, and anatomical parameters. DFP
36  2011 Reduction of retrograde axonal transport associated-proteins motor proteins, dynein and dynactin in the spinal cord and cerebral cortex of hens by tri-ortho-cresyl phosphate (TOCP). PMSF, TOCP
37  2011 [Screening the proteins of organophosphoms ester-induced delayed neurotoxicity in the cerebral tissue of hens exposed to tri-ortho-cresyl phosphate]. TOCP
38  2010 Changes of mitochondrial ultrastructures and function in central nervous tissue of hens treated with tri-ortho-cresyl phosphate (TOCP). MPT, MTT, TOCP
39  2010 Modulation of dopaminergic system and neurobehavioral functions in delayed neuropathy induced by organophosphates. OPs
40  2010 Motor neuron disease due to neuropathy target esterase gene mutation: clinical features of the index families. NTE
41  2010 Pharmacological agents in the prophylaxis/treatment of organophosphorous pesticide intoxication. Hu BChE, IMS, NTE
42  2010 [Changes of pathologic feature and microtubulin associated protein 2 in nervous system of hens with organophosphate-induced delayed neuropathy induced by 2,4,6-trimethylbenzoyl phenylphosphonate]. MAP2
43  2009 DFP initiated early alterations of PKA/p-CREB pathway and differential persistence of beta-tubulin subtypes in the CNS of hens contributes to OPIDN. CNS, DFP, pCREB
44  2009 Identification and characterization of chicken neuropathy target esterase. cNTE, GFP, NTE
45  2009 Impaired mitochondrial functions in organophosphate induced delayed neuropathy in rats. ---
46  2009 Motor neuron diseases and neurotoxic substances: a possible link? MNDs, NTE
47  2009 Neurofilaments degradation as an early molecular event in tri-ortho-cresyl phosphate (TOCP) induced delayed neuropathy. TOCP
48  2009 Phenylmethylsulfonyl fluoride protects against the degradation of neurofilaments in tri-ortho-cresyl phosphate (TOCP) induced delayed neuropathy. NF, PMSF, TOCP
49  2009 Thirteen-year follow-up of patients with tri-ortho-cresyl phosphate poisoning in northern suburbs of Xi'an in China. CMCT, MEP, OP, TOCP
50  2008 Antibodies to neural proteins in organophosphorus-induced delayed neuropathy (OPIDN) and its amelioration. GFAP, MBP, NF, NTE, PSP
51  2008 Degradation of neuropathy target esterase by the macroautophagic lysosomal pathway. NTE
52  2008 Effects of calcium gluconate and PMSF in the treatment of acute intoxication of chicken by TOCP. LNTE, TOCP
53  2008 Molecular cloning and expression analysis of cDNA ends of chicken neuropathy target esterase. bp, NTE, ORF, RACE
54  2008 The homeostasis of phosphatidylcholine and lysophosphatidylcholine was not disrupted during tri-o-cresyl phosphate-induced delayed neurotoxicity in hens. GPC, LPC, LysoPLA, NTE, OP, PC, PLB, PMSF, TOCP
55  2007 Axonal degeneration and neuropathy target esterase. ER, NTE, PtdCho
56  2007 Molecular cloning and expression of chicken neuropathy target esterase activity domain. EGFP, NTE
57  2007 Time-dependent changes of lipid peroxidation and antioxidative status in nerve tissues of hens treated with tri-ortho-cresyl phosphate (TOCP). TOCP
58  2007 Verapamil abolished the enhancement of protein phosphorylation of brainstem mitochondria and synaptosomes from the hens dosed with tri-o-cresyl phosphate. TOCP
59  2007 [Tri-ortho-cresyl phosphate induced oligodendrocyte vacuolation and process degeneration in cultured hen oligodendrocytes]. MTT, TOCP
60  2006 Aberrant activation of CDK5 is involved in the pathogenesis of OPIDN. Cdk5, TOCP
61  2006 Expression changes of neurofilament subunits in the central nervous system of hens treated with tri-ortho-cresyl phosphate (TOCP). GAPDH, NF-L, NF-M, NFs, RT-PCR, SDS-PAGE, TOCP
62  2006 Inhibition of neurite outgrowth in differentiating mouse N2a neuroblastoma cells by phenyl saligenin phosphate: effects on MAP kinase (ERK 1/2) activation, neurofilament heavy chain phosphorylation and neuropathy target esterase activity. NFH, NTE, PSP
63  2006 Screening pesticides for neuropathogenicity. ---
64  2006 The L-type calcium channel blocker nimodipine mitigates cytoskeletal proteins phosphorylation in dichlorvos-induced delayed neurotoxicity in rats. MAP-2
65  2006 Toxicogenomic studies of the rat brain at an early time point following acute sarin exposure. PCA
66  2006 Triorthocresyl phosphate-induced neuronal losses in lumbar spinal cord of hens--an immunohistochemistry and ultrastructure study. TOCP
67  2005 [Effects of methamidophos on microtubule and microfilament proteins in sciatic nerve of hens]. ---
68  2004 Effects of prednisolone and complex of vitamin B1, B2, B6 and B12 on organophosphorus compound-induced delayed neurotoxicity. OPs, TOCP
69  2004 Neurofilament 200 as an indicator of differences between mipafox and paraoxon sensitivity in Sy5Y neuroblastoma cells. GAP43, MAP2ab, OP
70  2004 Organophosphorus ester-induced chronic neurotoxicity. OPICN
71  2004 Preliminary characterisation of an in vitro paradigm for the study of the delayed effects of organophosphorus compounds: hen embryo brain spheroids. AChE, HEBS, NTE, OP
72  2004 Tri-ortho-cresyl phosphate (TOCP) decreases the levels of cytoskeletal proteins in hen sciatic nerve. IOD, NF, NF-H, NF-M, NfL, TOCP
73  2004 [Spinal cord neuronal apoptosis induced by triorthocresyl phosphate poisoning in hens]. TOCP
74  2003 Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds. NGF, NTE, OP
75  2003 NTE: one target protein for different toxic syndromes with distinct mechanisms? NTE
76  2003 Organophosphate-induced delayed neuropathy: case report. OPIDP
77  2003 The effect of Calcicol as calcium tonic on delayed neurotoxicity induced by organophosphorus compounds. OPs, TOCP
78  2003 [Neurotoxicity of organophosphorus and dithiocarbamate compounds]. AChE, NTE, OPs
79  2002 Characterization of binding sites for diisopropyl phosphorofluoridate in spinal cord cytosol. AChE, NTE
80  2002 Differential alteration of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA in the central nervous system of hens treated with diisopropylphosphorofluoridate (DFP). CaMK-II, DFP, GAPDH, NO, pCREB, PKA
81  2002 Low level exposures to organophosphorus esters may cause neurotoxicity. COPIND, LTLL, OP
82  2002 Organophosphate induced delayed neuropathy in genetically dissimilar chickens: studies with tri-ortho-cresyl phosphate (TOCP) and trichlorfon. Br.ChE, Br.NTE, pl.ChE, TOCP
83  2002 Protein levels of neurofilament subunits in the hen central nervous system following prevention and potentiation of diisopropyl phosphorofluoridate (DFP)-induced delayed neurotoxicity(1). DFP, NF, NFs, PMSF
84  2001 A comparative study of binding sites for diisopropyl phosphorofluoridate in membrane and cytosol preparations from spinal cord and brain of hens. ChE, DFP, NTE, OPs
85  2001 Altered time course of mRNA expression of alpha tubulin in the central nervous system of hens treated with diisopropyl phosphorofluoridate (DFP). DFP
86  2001 Correlation of binding sites for diisopropyl phosphorofluoridate with cholinesterase and neuropathy target esterase in membrane and cytosol preparations from hen. ChE, DFP, NTE
87  2001 Early differential induction of C-jun in the central nervous system of hens treated with diisopropylphosphorofluoridate (DFP). DFP
88  2001 Enhanced activity and level of protein kinase A in the spinal cord supernatant of diisopropyl phosphorofluoridate (DFP)-treated hens. Distribution of protein kinases and phosphatases in spinal cord subcellular fractions. CaM kinase II, DFP, NF, PKA, PKC, PP1, PP2A, PP2B
89  2001 High-dose intravenous paraoxon exposure does not cause organophosphate-induced delayed neuropathy (OPIDN) in mini pigs. BW, NTE, PX
90  2001 Inhibition of calcium-stimulated ATPase in the hen brain P2 synaptosomal fraction by organophosphorus esters: relevance to delayed neuropathy. DFP, OP, PSP, TOTP
91  2001 Nerve conduction and ATP concentrations in sciatic-tibial and medial plantar nerves of hens given phenyl saligenin phosphate. ATP, PSP
92  2001 Peripheral cholinesterase inhibition by occupational chlorpyrifos exposure in Australian termiticide applicators. ChE, EAChE, NTE, OPs, PCOs, SChE
93  2001 Possible role of enhanced microtubule phosphorylation in dichlorvos induced delayed neurotoxicity in rat. MAP-2
94  2000 Alterations in levels of mRNAs coding for glial fibrillary acidic protein (GFAP) and vimentin genes in the central nervous system of hens treated with diisopropyl phosphorofluoridate (DFP). DFP, GFAP, IF
95  2000 Altered expression of neurofilament subunits in diisopropyl phosphorofluoridate-treated hen spinal cord and their presence in axonal aggregations. DFP, NF, NF-M
96  2000 Brainstem axolemmal protein phosphorylation in vitro in hens dosed with di-1-butyl-2,2-dichlorovinyl phosphate. SDS-PAGE, TOCP
97  2000 C-fos mRNA induction in the central and peripheral nervous systems of diisopropyl phosphorofluoridate (DFP)-treated hens. CaM kinase II, DFP, IEG, NF
98  2000 Immunohistochemical study of phosphorylated neurofilaments during the evolution of organophosphorus ester-induced delayed neuropathy (OPIDN). ---
99  1999 A new approach for determination of neuropathy target esterase activity. NTE, OPs, PV
100  1999 A stable preparation of hen brain neuropathy target esterase for rapid biochemical assessment of neurotoxic potential of organophosphates. NTE, OP