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Abbreviation : OSC
Long Form : Oxysophocarpine
No. Year Title Co-occurring Abbreviation
2018 Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion. IL, LDH, MMP, OGD, TNF-alpha
2018 Oxysophocarpine Retards the Growth and Metastasis of Oral Squamous Cell Carcinoma by Targeting the Nrf2/HO-1 Axis. HO-1, IHC, Nrf2, OSCC
2017 Oxysophocarpine inhibits lung injury induced by respiratory syncytial virus. IL-6, RSV
2017 Oxysophocarpine reduces oxygen-glucose deprivation-induced microglial activation and injury. IL, MyD88, NF, OGD/R, TLR4
2017 The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice. EEG, FJB, MDA, PILO, SE
2015 Human microsomal cyttrochrome P450-mediated reduction of oxysophocarpine, an active and highly toxic constituent derived from Sophora flavescens species, and its intestinal absorption and metabolism in rat. SC
2014 Neuroprotective effects of oxysophocarpine on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion. ER, MMP, NIM, OGD/RP
2013 Oxysophocarpine induces anti-nociception and increases the expression of GABAAalpha1 receptors in mice. GABAAalpha1, i.c.v, i.p, MPE
2007 Simultaneous quantification of oxysophocarpine and its active metabolite sophocarpine in rat plasma by liquid chromatography/mass spectrometry for a pharmacokinetic study. ESI, SC, SIM