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Abbreviation : P-gp
Long Form : P-glycoprotein
No. Year Title Co-occurring Abbreviation
2020 5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells. CRC, MDR, NSCLC
2020 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers. ---
2020 A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance. MDR
2020 A Co-Delivery System of Curcumin and p53 for Enhancing the Sensitivity of Drug-Resistant Ovarian Cancer Cells to Cisplatin. bax, CUR, MMP9, mRNA, NLS, PEI
2020 A Combination of Clioquinol, Zinc and Copper Increases the Abundance and Function of Breast Cancer Resistance Protein in Human Brain Microvascular Endothelial Cells. BBB, BCRP, BP, CQ
2020 A liquid biopsy to detect multidrug resistance and disease burden in multiple myeloma. MDR, MPs, PS
2020 A novel approach of targeting refractory epilepsy: Need of an hour. ---
2020 A Novel Approach to Refractory Epilepsy by Targeting Pgp peripherally and centrally: Therapeutic targets and Future perspectives. AEDs, COX-II, MDR
2020 A pH/ROS cascade-responsive and self-accelerating drug release nanosystem for the targeted treatment of multi-drug-resistant colon cancer. EPR, Lapa, MDR, PHis, PLP-NPs, PTX, ROS
10  2020 A Review of the Pharmacological Properties of Psoralen. AChE, AP-1, ASK1, ATF, BMP, CHOP, HPA, IRE1, JNK, MMPs, PERK, pol, PPARgamma, TCM, TGF-beta, TNF-alpha
11  2020 A sequentially responsive nanosystem breaches cascaded bio-barriers and suppresses P-glycoprotein function for reversing cancer drug resistance. CD-PEI, DOX, MDR
12  2020 A telomerase-responsive nanoprobe with theranostic properties in tumor cells. ASO, DOX, MDR, MDR1
13  2020 ABCB1 Genetic Variants as Predictors of Irinotecan-Induced Severe Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients. mCRC
14  2020 Active transport of rhodamine 123 by the human multidrug transporter P-glycoprotein involves two independent outer gates. ---
15  2020 Advanced nanoscale carrier-based approaches to overcome biopharmaceutical issues associated with anticancer drug 'Etoposide'. CNTs, ETS, NPs
16  2020 An Adaptive Physiologically Based Pharmacokinetic-Driven Design to Investigate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Molibresib (GSK525762) in Healthy Female Volunteers. PBPK
17  2020 An original radio-biomimetic approach to synthesize radiometabolites for PET imaging. BBB, BUP, PET, RBM
18  2020 Antitumor Effects of Docetaxel in Truncated Basic Fibroblast Growth Factor- Functionalized Liposomes Delivered by d-alpha-tocopheryl Polyethylene Glycol 2000 Succinate. ---
19  2020 Aptamer-Functionalized DNA Origami for Targeted Codelivery of Antisense Oligonucleotides and Doxorubicin to Enhance Therapy in Drug-Resistant Cancer Cells. ADR, AFM, Apt-DOA, Apt-origami-ASO, Bcl-2, PBS, qRT-PCR
20  2020 Assessment of contribution of BCRP to intestinal absorption of various drugs using portal-systemic blood concentration difference model in mice. AQ, BCRP, NCEs, P-S, WT
21  2020 Association of Oral Anticoagulants and Verapamil or Diltiazem With Adverse Bleeding Events in Patients With Nonvalvular Atrial Fibrillation and Normal Kidney Function. DOACs
22  2020 Automated synthesis, preclinical toxicity, and radiation dosimetry of [18F]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier. ---
23  2020 BCLAF1 promotes cell proliferation, invasion and drug-resistance though targeting lncRNA NEAT1 in hepatocellular carcinoma. 5-FU, BCLAF1, MRP1, NEAT1
24  2020 Benzophenone Sulfonamide Derivatives as Interacting Partners and Inhibitors of Human P-glycoprotein. ABC, CEM, MDR, TM
25  2020 Bergamottin can be used to assess CYP3A-mediated intestinal first-pass metabolism without affecting P-glycoprotein-mediated efflux in rats. ---
26  2020 beta3-Adrenoreceptor Blockade Reduces Hypoxic Myeloid Leukemic Cells Survival and Chemoresistance. beta3-AR, BMCs, PBMCs
27  2020 Bleeding and thromboembolism due to drug-drug interactions with non-vitamin K antagonist oral anticoagulants-a Swedish, register-based cohort study in atrial fibrillation outpatients. HR, NOACs
28  2020 Blocking of efflux transporters in rats improves translational validation of brain radioligands. PET
29  2020 Boosting drug bioavailability in men but not women through the action of an excipient. PEG 400
30  2020 Brain Microvascular Endothelial Cell Derived Exosomes Potently Ameliorate Cognitive Dysfunction by Enhancing the Clearance of Abeta Through Up-Regulation of P-gp in Mouse Model of AD. AD, BBB, HBMVECs
31  2020 Breed is associated with the ABCB1-1Delta mutation in Australian dogs. ---
32  2020 Ca2+ signaling modulation using cancer cell membrane coated chitosan nanoparticles to combat multidrug resistance of cancer. CCM, DOX, MDR
33  2020 Caffeic Acid Attenuates Multi-Drug Resistance in Cancer Cells by Inhibiting Efflux Function of Human P-glycoprotein. MDR
34  2020 Canagliflozin inhibits p-gp function and early autophagy and improves the sensitivity to the antitumor effect of doxorubicin. CAN, DOX
35  2020 Cancer Stem Cells as a Potential Target to Overcome Multidrug Resistance. ABC, CSCs, MDR
36  2020 Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions. AEDs, CBD, MDR, RE, Rho-123, Tq
37  2020 Celecoxib Prevents Doxorubicin-Induced Multidrug Resistance in Canine and Mouse Lymphoma Cell Lines. MDR
38  2020 Characterisation of Hybrid Polymersome Vesicles Containing the Efflux Pumps NaAtm1 or P-Glycoprotein. ABC, CAM
39  2020 Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening. ---
40  2020 Characterization of the Blood-Brain Barrier Integrity and the Brain Transport of SN-38 in an Orthotopic Xenograft Rat Model of Diffuse Intrinsic Pontine Glioma. ABC, BBB, DIPG, TRD
41  2020 Chemical molecular-based approach to overcome multidrug resistance in cancer by targeting P-glycoprotein (P-gp). ABC, MDR, SAR
42  2020 Chronic Inhibition of CYP3A is Temporarily Reduced by Each Hemodialysis Session in Patients With End-Stage Renal Disease. CYP3A, OATP
43  2020 Chrysosporazines F-M: P-Glycoprotein Inhibitory Phenylpropanoid Piperazines from an Australian Marine Fish Derived Fungus, Chrysosporium sp. CMB-F294. ---
44  2020 Circ-PRKDC Contributes to 5-Fluorouracil Resistance of Colorectal Cancer Cells by Regulating miR-375/FOXM1 Axis and Wnt/beta-Catenin Pathway. 5-FU, CCK-8, circRNAs, CRC, FOXM1, miR-375, MRP1, qRT-PCR, RIP
45  2020 Clinically relevant drug interactions between statins and antidepressants. AEs, DDIs, PD, PK
46  2020 Co-delivery of Poria cocos extract and doxorubicin as an 'all-in-one' nanocarrier to combat breast cancer multidrug resistance during chemotherapy. DOX, MDR
47  2020 Co-Encapsulation of Mitoxantrone and beta-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia. beta-E, DOX, MDR, MTO
48  2020 Coencapsulation of disulfiram and doxorubicin in liposomes strongly reverses multidrug resistance in breast cancer cells. DOX, DSF, LipoDSF-DOX
49  2020 Combinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin. SNPs
50  2020 Combined effects of berberine and evodiamine on colorectal cancer cells and cardiomyocytes in vitro. Nrf2
51  2020 Combining Machine Learning and Molecular Dynamics to Predict P-Glycoprotein Substrates. MDFPs, ML
52  2020 Comparative study of transcription profiles of the P-glycoprotein transporters of two Haemonchus contortus isolates: Susceptible and resistant to ivermectin. ---
53  2020 Construction of Pepstatin A-Conjugated ultrasmall SPIONs for targeted positive MR imaging of epilepsy-overexpressed P-glycoprotein. KA, MR, PA, USPIONs
54  2020 Correlation of levetiracetam concentration in peripheral blood mononuclear cells with clinical efficacy: A sensitive monitoring biomarker in patients with epilepsy. AED, Cu.PBMC, Cu.serum, LEV, TDM
55  2020 Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane. ---
56  2020 Curcumin increases the sensitivity of K562/DOX cells to doxorubicin by targeting S100 calcium-binding protein A8 and P-glycoprotein. CML, DOX, MDR, S100A8
57  2020 Curcumin-Loaded Solid Lipid Nanoparticles Bypass P-Glycoprotein Mediated Doxorubicin Resistance in Triple Negative Breast Cancer Cells. ATP, CURC, MDR, SLNs, TNBC
58  2020 Deep Sequencing Analysis Reveals Distinctive Non-Coding RNAs When Comparing Tumor Multidrug-Resistant Cells and Extracellular Vesicles with Drug-Sensitive Counterparts. EVs, MDR
59  2020 Description of Druglike Properties of Safranal and Its Chemistry behind Low Oral Exposure. BCRP
60  2020 Developmental patterns in human blood-brain barrier and blood-cerebrospinal fluid barrier ABCdrug transporter expression. BBB, BCRP, BCSFB, GA, PMA, PNA
61  2020 Dextran sulfate sodium-induced colitis and ginseng intervention altered oral pharmacokinetics of cyclosporine A in rats. CS, CsA, CYP3A, DSS, TJ, UC
62  2020 Diltiazem potentiates the cytotoxicity of gemcitabine and 5-fluorouracil in PANC-1 human pancreatic cancer cells through inhibition of P-glycoprotein. 5-FU, PC
63  2020 Direct-acting antiviral interactions with opioids, alcohol or illicit drugs of abuse in HCV-infected patients. DAAs, HCV, PD, PKs
64  2020 Diterpenoids from Euphorbia royleana reverse P-glycoprotein-mediated multidrug resistance in cancer cells. MDR
65  2020 DJ-1 is involved in the multidrug resistance of SGC7901 gastric cancer cells through PTEN/PI3K/Akt/Nrf2 pathway. MDR
66  2020 Donepezil, a cholinesterase inhibitor used in Alzheimer's disease therapy, is actively exported out of the brain by abcb1ab p-glycoproteins in mice. BBB, KO, s.c, WT
67  2020 Downregulation of MDR 1 gene contributes to tyrosine kinase inhibitor induce apoptosis and reduction in tumor metastasis: A gravity to space investigation. IM, MDR, PAMAM, si-MDR1, siRNA
68  2020 Downregulation of peripheral PTGS2/COX-2 in response to valproate treatment in patients with epilepsy. BBB, PGE2, VA
69  2020 Doxorubicin Encapsulated in TPGS-Modified 2D-Nanodisks Overcomes Multidrug Resistance. DOX, MDR
70  2020 Drug Interactions for Low-Dose Inhaled Nemiralisib: A Case Study Integrating Modeling, In Vitro, and Clinical Investigations. DDI, PBPK
71  2020 Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer. CRC
72  2020 Drug-induced liver injury in a COVID-19 patient: potential interaction of remdesivir with P-glycoprotein inhibitors. ---
73  2020 Dual drug-loaded nano-platform for targeted cancer therapy: toward clinical therapeutic efficacy of multifunctionality. GA, PTX
74  2020 Dual P-Glycoprotein and CA XII Inhibitors: A New Strategy to Reverse the P-gp Mediated Multidrug Resistance (MDR) in Cancer Cells. CA XII, MDR
75  2020 Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders. ABC, BBB, BCRP, CNS, MPRs
76  2020 Early downregulation of P-glycoprotein facilitates bacterial attachment to intestinal epithelial cells and thereby triggers barrier dysfunction in a rodent model of total parenteral nutrition. E. coli, IECs, TPN
77  2020 Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance. ---
78  2020 Edoxaban and the Issue of Drug-Drug Interactions: From Pharmacology to Clinical Practice. DDIs, NOACs, NVAF, VTE
79  2020 Effect of air pre-exposure on Tetrabromobisphenol A resistance in the clam Ruditapes philippinarum. TBBPA
80  2020 Effect of Baizhu (Rhizoma Atractylodis Macrocephalae) extract on intestinal absorption of brucine and strychnine in vitro and in situ. NUX
81  2020 Effect of co-administration of Acori Tatarinowii Rhizoma volatile oil on pharmacokinetic fate of xanthotoxol, oxypeucedanin hydrate, and byakangelicin from Angelicae Dahuricae Radix in rat. ---
82  2020 Effect of Colloidal Aqueous Solution of Fullerene (C60) in the Presence of a P-Glycoprotein Inhibitor (Verapamil) on Spatial Memory and Hippocampal Expression of Sirtuin6, SELADIN1, and AQP1 Genes in a Rat Model of Alzheimer's Disease. AD, DNPZL, HPLC, SCOP, TACs
83  2020 Effect of Food and an Animal's Sex on P-Glycoprotein Expression and Luminal Fluids in the Gastrointestinal Tract of Wistar Rats. GI
84  2020 Effect of GenX on P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 at the Blood-Brain Barrier. BBB, BCRP, MRP2, PPARgamma
85  2020 Effect of Natural Phenolics on Pharmacokinetic Modulation of Bedaquiline in Rat to Assess the Likelihood of Potential Food-Drug Interaction. MDR-TB
86  2020 Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug-Drug Interaction Studies. CAR, CYP450, DDIs, PK, PXR
87  2020 Effect of P-glycoprotein on the availability of oxime reactivators in the brain. AChE, BBB, CNS
88  2020 Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. AUC, OATP1A2, R. acetosa
89  2020 Effect of treatment period with LC478, a disubstituted adamantayl derivative, on P-glycoprotein inhibition: its application to increase docetaxel absorption in rats. ---
90  2020 Effect of verapamil in the reversal of doxorubicin chemotherapy resistance in advanced gastric cancer. GCS, VER
91  2020 Effect simultaneous delivery with P-glycoprotein inhibitor and nanoparticle administration of doxorubicin on cellular uptake and in vitro anticancer activity. DoxNP, DoxS, MDR
92  2020 Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. CI
93  2020 Effects of Maribavir on P-Glycoprotein and CYP2D6 in Healthy Volunteers. CIs, GMRs
94  2020 Effects of paroxetine, ketoconazole, and rifampin on the metabolism of eliglustat, an oral substrate reduction therapy for Gaucher disease type 1. ---
95  2020 Effects of Selected Nigerian Medicinal Plants on the Viability, Mobility, and Multidrug-Resistant Mechanisms in Liver, Colon, and Skin Cancer Cell Lines. ---
96  2020 Effects of verapamil on the pharmacokinetics of ivermectin in rabbits. IVM, s.c
97  2020 Enabling P-glycoprotein inhibition in multidrug resistant cancer through the reverse targeting of a quinidine-PEG conjugate. mPEG
98  2020 Engineering of a Core-Shell Nanoplatform to Overcome Multidrug Resistance via ATP Deprivation. ATP, DOX, GOx, MDR, MPDA, ZIF-8
99  2020 Enhanced antitumor efficacy of bile acid-lipid complex-anchored docetaxel nanoemulsion via oral metronomic scheduling. DLNE, DOCA, DOTAP, DTX, LMC, NE
100  2020 Enhanced Intestinal Absorption and Pharmacokinetic Modulation of Berberine and Its Metabolites through the Inhibition of P-Glycoprotein and Intestinal Metabolism in Rats Using a Berberine Mixed Micelle Formulation. ---