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Abbreviation : PAEC
Long Form : pulmonary artery endothelial cells
No. Year Title Co-occurring Abbreviation
2020 AMP-Kinase Dysfunction Alters Notch Ligands to Impair Angiogenesis in Neonatal Pulmonary Hypertension. Dll4, ETC, Jag1, PPHN
2020 Expression of human thrombomodulin on porcine endothelial cells can reduce platelet aggregation but did not reduce activation of complement or endothelium - an experimental study. TMA
2020 PPARgamma is a gatekeeper for extracellular matrix and vascular cell homeostasis: beneficial role in pulmonary hypertension and renal/cardiac/pulmonary fibrosis. EPCs, PAH, PASMC, PPARgamma, TZD
2019 Altered hypoxia-inducible factor-1alpha (HIF-1alpha) signaling contributes to impaired angiogenesis in fetal lambs with persistent pulmonary hypertension of the newborn (PPHN). Hek-2, HIF-1alpha, PPHN, siRNA, VEGF
2019 Endogenous hydrogen sulfide sulfhydrates IKKbeta at cysteine 179 to control pulmonary artery endothelial cell inflammation. C179S, CSE, DTT, IKKbeta, NF-kappaB, PAH
2019 Heterogeneous response of endothelial cells to insulin-like growth factor 1 treatment is explained by spatially clustered sub-populations. IGF-1, PPHN
2019 Human TIGIT on porcine aortic endothelial cells suppresses xenogeneic macrophage-mediated cytotoxicity. PAEC/TIGIT, TIGIT
2019 Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension. PAH, TCA
2019 Selective inhibition of cyclooxygenase-2 protects porcine aortic endothelial cells from human antibody-mediated complement-dependent cytotoxicity. COX-2, IL-1beta, NF-kappaB, NSAIDs, PI, qPCR, siRNA, TNF-alpha
10  2018 An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis. EBD, i.p
11  2018 Apple polyphenol relieves hypoxia-induced pulmonary arterial hypertension via pulmonary endothelium protection and smooth muscle relaxation: In vivo and in vitro studies. APP, mPAP, PAH, PASMC, PE, PVR
12  2018 Galectin-3- Mediated Transdifferentiation of Pulmonary Artery Endothelial Cells Contributes to Hypoxic Pulmonary Vascular Remodeling. EndMT, Gal-3, PAH
13  2018 Intrauterine growth restriction decreases NF-kappaB signaling in fetal pulmonary artery endothelial cells of fetal sheep. ECM, IUGR
14  2018 Persistent pulmonary hypertension alters the epigenetic characteristics of endothelial nitric oxide synthase gene in pulmonary artery endothelial cells in a fetal lamb model. ChIP, eNOS, EREs, PPHN, RVSP, Sp1, TET
15  2017 Corneal Xenotransplantation From Pig to Rhesus Monkey: No Signs of Transmission of Endogenous Porcine Retroviruses. MVECs, PCR, PERVs, RT-PCR
16  2017 Endothelial colony-forming cells ameliorate endothelial dysfunction via secreted factors following ischemia-reperfusion injury. AKI, CM, ECFC, I/R, MBF, PMVEC
17  2017 Establishment and long-term culture of human cystic fibrosis endothelial cells. CF, EC
18  2017 Exosomes Derived from Human Pulmonary Artery Endothelial Cells Shift the Balance between Proliferation and Apoptosis of Smooth Muscle Cells. LPS, PASMC
19  2017 Genomic stability of pulmonary artery endothelial colony-forming cells in culture. ECFC, PAH
20  2017 MFG-E8-derived peptide attenuates adhesion and migration of immune cells to endothelial cells. BMDNs, C5a, MFG-E8, SPR
21  2017 NF-kappaB mediated miR-130a modulation in lung microvascular cell remodeling: Implication in pulmonary hypertension. BMPR2, MCT, miRNAs, MVEC, NF-kappaB, PAH, RVH
22  2017 Quercetin Inhibits Pulmonary Arterial Endothelial Cell Transdifferentiation Possibly by Akt and Erk1/2 Pathways. PAH
23  2017 Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood. CHC
24  2017 Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension. HERV-K, PAH, SAMHD1
25  2016 An In Vitro Hemodynamic Flow System to Study the Effects of Quantified Shear Stresses on Endothelial Cells. EC, LDV, PPFC, WSS
26  2016 Chemoattractant Signals and Adhesion Molecules Promoting Human Regulatory T Cell Recruitment to Porcine Endothelium. NK
27  2016 Inhibition of complement component C5 prevents clotting in an ex vivo model of xenogeneic activation of coagulation. AVR, GTKO, hCD46, PFP, PRP, TMA, WT, XNA
28  2016 Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells. eNOS, ETC, NT
29  2016 Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension. hPAECs, IPAH, PAH
30  2016 Peroxisome Proliferator-Activated Receptor gamma and microRNA 98 in Hypoxia-Induced Endothelin-1 Signaling. ET-1, miR, PCNA, PH, PPARgamma
31  2016 The hepatocyte growth factor isoform NK2 activates motogenesis and survival but not proliferation due to lack of Akt activation. BEpC, HGF
32  2016 The Warburg effect: A new story in pulmonary arterial hypertension. PAH, PAP, PASMCs
33  2016 Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. HMGB1, hTBM, LPS, PAI, WT
34  2015 Altered prostanoid metabolism contributes to impaired angiogenesis in persistent pulmonary hypertension in a fetal lamb model. PGIS, PPHN, TXAS
35  2015 Altered pulmonary artery endothelial-smooth muscle cell interactions in experimental congenital diaphragmatic hernia. CDH, PH, SMC
36  2015 Functional difference between membrane-bound and soluble human thrombomodulin. APC, hTM, MB-hTM, S-hTM, TF
37  2015 Genetic deficit of KCa 3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation. TRP, TRPV4, WT
38  2015 Interaction of endothelial nitric oxide synthase with mitochondria regulates oxidative stress and function in fetal pulmonary artery endothelial cells. eNOS, NOS, ROS
39  2015 microRNA and Pulmonary Hypertension. AdvFB, miRNAs, PAH, PASMC, RV
40  2015 Modulation of miRNAs in Pulmonary Hypertension. miRNAs, PASMC, PH, RVH
41  2014 Endothelin-1 decreases endothelial PPARgamma signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension. eNOS, ET-1, L-NA, PPARgamma, PPHN
42  2014 Glycated collagen decreased endothelial cell fibronectin alignment in response to cyclic stretch via interruption of actin alignment. CS, ECM, FAK, JNK, MMP-2, MT1-MMP
43  2014 Inducible HSP70 regulates superoxide dismutase-2 and mitochondrial oxidative stress in the endothelial cells from developing lungs. iHSP70, NO, PA, PPHN, SOD-2
44  2014 Sox18 preserves the pulmonary endothelial barrier under conditions of increased shear stress. PBF, TER
45  2014 Thymosin Beta 4 protects mice from monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy. MCT, PASMC, PH, RVH, Tbeta4
46  2014 Vitamin D treatment improves survival and infant lung structure after intra-amniotic endotoxin exposure in rats: potential role for the prevention of bronchopulmonary dysplasia. ATIIC, ETX, IA, VitD
47  2013 Activation of the lectin pathway of complement in pig-to-human xenotransplantation models. GalTKO, MBL, WT
48  2013 AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension. AMPK, eNOS, PDGFbeta, ROS, VEGF
49  2013 Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow. ADMA, CrAT, eNOS, NO, NOS, PBF
50  2013 EETs and CYP2J2 inhibit TNF-alpha-induced apoptosis in pulmonary artery endothelial cells and TGF-beta1-induced migration in pulmonary artery smooth muscle cells. CYP2J2, EETs, ERK, PASMC, PI3K, TGF-beta1, TNF-alpha
51  2013 Endothelial colony-forming cell conditioned media promote angiogenesis in vitro and prevent pulmonary hypertension in experimental bronchopulmonary dysplasia. AT2, BPD, CM, ECFCs, EPC
52  2013 High Pulsatility Flow Induces Acute Endothelial Inflammation through Overpolarizing Cells to Activate NF-kappaB. ---
53  2013 NF-kappaB pathway is involved in CRP-induced effects on pulmonary arterial endothelial cells in chronic thromboembolic pulmonary hypertension. CRP, CTEPH, ET-1, IKBKE, IL-6, PDTC, vWF
54  2013 Pulmonary artery endothelial cell dysfunction and decreased populations of highly proliferative endothelial cells in experimental congenital diaphragmatic hernia. CDH, HP-PAEC, NO, VEGF
55  2013 Pulmonary artery endothelial cell phenotypic alterations in a large animal model of pulmonary arteriovenous malformations after the Glenn shunt. PAVM, SCPC
56  2013 Serum can overcome contact inhibition in confluent human pulmonary artery smooth muscle cells. FBS, PASMC
57  2013 The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations. BMPR-II, BOECs, PAH
58  2013 X-irradiation induces ER stress, apoptosis, and senescence in pulmonary artery endothelial cells. CHOP, eIF2alpha, ER, GADD34, GRP78, Gy, SA-beta-gal, SIRT1
59  2012 Activation of JNK/c-Jun is required for the proliferation, survival, and angiogenesis induced by EET in pulmonary artery endothelial cells. EET, PAH, PVR
60  2012 Angiotensin II regulates activation of Bim via Rb/E2F1 during apoptosis: involvement of interaction between AMPKbeta1/2 and Cdk4. AMPK, Ang II, BH3, CDK4, Rb
61  2012 Complete absence of the alphaGal xenoantigen and isoglobotrihexosylceramide in alpha1,3galactosyltransferase knock-out pigs. ---
62  2012 Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension. NOX, PPHN
63  2012 Decreases in manganese superoxide dismutase expression and activity contribute to oxidative stress in persistent pulmonary hypertension of the newborn. eNOS, MnSOD, NO, PPHN
64  2012 Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension. ACE, bPASMCs, hPAECs, PAH, TPH1
65  2012 Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells. CrAT, NO, PBF
66  2012 Role of NF-kappaB activation in LPS-induced endothelial barrier breakdown. HDMEC, LPS, NBD, TER, VASP
67  2012 Serotonin passes through myoendothelial gap junctions to promote pulmonary arterial smooth muscle cell differentiation. PASMCs, TPH1
68  2012 Studies on coagulation incompatibilities for xenotransplantation. FVIIa, FXa, HUVEC, PC, TF, TFPI, TM
69  2012 Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide production. eNOS, hPAECs, PPHN, VDAC
70  2011 Angiotensin II activates AMPK for execution of apoptosis through energy-dependent and -independent mechanisms. AMPK, Ang, SHP-2
71  2011 Bone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation. BMP, eNOS, NO, PAH, PKA
72  2011 Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease. ANGPT2, CHD, siRNA
73  2011 Gene transfer of the adaptor Lnk (SH2B3) prevents porcine endothelial cell activation and apoptosis: implication for xenograft's cytoprotection. EC, TNF, XNA
74  2011 Intrauterine growth restriction decreases pulmonary alveolar and vessel growth and causes pulmonary artery endothelial cell dysfunction in vitro in fetal sheep. BPD, eNOS, IUGR, NO
75  2011 Modulation of hydrogen peroxide production in cellular systems by low level magnetic fields. ROS, SOD
76  2011 Nitrotyrosine impairs angiogenesis and uncouples eNOS activity of pulmonary artery endothelial cells isolated from developing sheep lungs. eNOS, Hsp90, NT
77  2011 Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension. ECFC, PAH
78  2011 Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase. GCH1, Hsp90, NO, PPHN, SEP
79  2011 Shear stress induces the release of an endothelial elastase: role in integrin alpha(v)beta(3)-mediated FGF-2 release. FGF-2
80  2011 Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys. AVR, EC, hHO-1, HO-1
81  2010 eNOS-beta-actin interaction contributes to increased peroxynitrite formation during hyperoxia in pulmonary artery endothelial cells and mouse lungs. eNOS, NO, ROS
82  2010 Potential value of human thrombomodulin and DAF expression for coagulation control in pig-to-human xenotransplantation. APC, HAEC, hDAF, hDAF-PAEC, hTM-PAEC, TM
83  2010 Role of Rho kinase in sphingosine 1-phosphate-mediated endothelial and smooth muscle cell migration and differentiation. S1P
84  2010 Shear stress stimulates nitric oxide signaling in pulmonary arterial endothelial cells via a reduction in catalase activity: role of protein kinase C delta. eNOS, ROS
85  2009 Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. beta-C, BMP, Dvl, pSmad1
86  2009 Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension. EPAS1, ESTs, HMMR, PH, PPARgamma
87  2009 Galectin-3-mediated xenoactivation of human monocytes. DXR
88  2009 Hypoxic upregulation of preproendothelin-1 gene expression is associated with protein tyrosine kinase-PI3K signaling in cultured lung vascular endothelial cells. ET-1, PI3K, qRT-PCR
89  2009 In vitro and in vivo effects of the carbon monoxide-releasing molecule, CORM-3, in the xenogeneic pig-to-primate context. CO, Con A, CORM-3, PBMC, TNF-alpha
90  2009 Increased superoxide production contributes to the impaired angiogenesis of fetal pulmonary arteries with in utero pulmonary hypertension. APO, NAC, NOX, PPHN
91  2009 Peptide-stimulation enhances compartmentalization and the catalytic activity of lung endothelial NOS. CD, ChOx, eNOS, GC, NGC, PM
92  2009 Transforming growth factor-beta1 causes pulmonary microvascular endothelial cell apoptosis via ALK5. PMVEC, TGF
93  2008 Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction. ADMA, eNOS, eNOS, NO
94  2008 Betamethasone attenuates oxidant stress in endothelial cells from fetal lambs with persistent pulmonary hypertension. ATP, eNOS, ET-B, Hsp90, NO, NOS, PPHN, SNAP, SOD
95  2008 Characterization of porcine UL16-binding protein 1 endothelial cell surface expression. CMV, IFN-gamma, NK, pEC, pULBP1, TNF-alpha
96  2008 Differential role of Rho GTPases in endothelial barrier regulation dependent on endothelial cell origin. CNFy, HDMEC, LT, MesEnd, MyEnd
97  2008 Effects of 2-deoxy-D-glucose on proliferation of vascular smooth muscle cells and endothelial cells. 2-DG, PSMC
98  2008 Endothelial alpha-1-antitrypsin attenuates cigarette smoke induced apoptosis in vitro. AAT, CS
99  2008 Lysyl oxidase (LOX) down-regulation by TNFalpha: a new mechanism underlying TNFalpha-induced endothelial dysfunction. BAEC, HUVEC, LOX, TNFR, TRAF2
100  2008 MIP-2 causes differential activation of RhoA in mouse aortic versus pulmonary artery endothelial cells. EC, MIP-2