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Abbreviation : PAMs
Long Form : porcine alveolar macrophages
No. Year Title Co-occurring Abbreviation
2019 14-3-3epsilon acts as a proviral factor in highly pathogenic porcine reproductive and respiratory syndrome virus infection. HP-PRRSV, LP-PRRSV, nsp2
2019 A Nanobody Targeting Viral Nonstructural Protein 9 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication. PRRS, Tat
2019 Antiviral Role of IFITM Proteins in Classical Swine Fever Virus Infection. CSFV
2019 Chlorine dioxide inhibits the replication of porcine reproductive and respiratory syndrome virus by blocking viral attachment. PRRS, PRRSV
2019 Evaluation of the Inhibitory Effects of (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one (DiNap), a Natural Product Analog, on the Replication of Type 2 PRRSV In Vitro and In Vivo. DiNap, PRRS, PRRSV
2019 Haemophilus parasuis infection in 3D4/21 cells induces autophagy through the AMPK pathway. H. parasuis, Hps5
2019 In vitro observation: the GFP-E. coli adhering to porcine erythrocytes can be removed by porcine alveolar macrophages. FITC, ICs
2019 Inhibitory effect of iota-carrageenan on porcine reproductive and respiratory syndrome virus in vitro. CG, PRRSV
2019 Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages. ATF6, Cap, ERS, IRE1, ORF5, PCV2, PCVD, TEM, UPR
10  2019 Replication and virulence in pigs of the first African swine fever virus isolated in China. ASF, HAD, p.c, p.i
11  2019 The miRNA-targeted transcriptome of porcine alveolar macrophages upon infection with Porcine Reproductive and Respiratory Syndrome Virus. RISC
12  2018 Actinobacillus pleuropneumoniae culture supernatant antiviral effect against porcine reproductive and respiratory syndrome virus occurs prior to the viral genome replication and transcription through actin depolymerization. APP, PRRSV, sgRNAs
13  2018 Activation of AMPK-dependent SIRT-1 by astragalus polysaccharide protects against ochratoxin A-induced immune stress in vitro and in vivo. APS, OTA
14  2018 Activation of Porcine Alveolar Macrophages by Actinobacillus pleuropneumoniae Lipopolysaccharide via the Toll-Like Receptor 4/NF-kappaB-Mediated Pathway. IL-1beta, LPS, TLR4
15  2018 Activation of the porcine alveolar macrophages via toll-like receptor 4/NF-kappaB mediated pathway provides a mechanism of resistin leading to inflammation. IL-1beta, MyD88, NF-kappaB, PBMC, TLR4, TNF-alpha, TRAM
16  2018 Different susceptibility to porcine reproductive and respiratory syndrome virus infection among Chinese native pig breeds. hpi, PRRSV, TLR3
17  2018 Galectin-3 inhibits replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp12 in vitro. gal-3, Nsp12, PRRS, PRRSV
18  2018 Identification of Differentially Expressed Non-coding RNA in Porcine Alveolar Macrophages from Tongcheng and Large White Pigs Responded to PRRSV. DE-miRNAs, LW, PRRS, PRRSV, TC
19  2018 Identification of the RNA Pseudoknot within the 3' End of the Porcine Reproductive and Respiratory Syndrome Virus Genome as a Pathogen-Associated Molecular Pattern To Activate Antiviral Signaling via RIG-I and Toll-Like Receptor 3. EAV, IFNs, ISGs, LDV, PAMPs, PRRs, PRRS, PRRSV, RIG-I, SHFV, TLR3, UTR
20  2018 In vitro immune responses of porcine alveolar macrophages reflect host immune responses against porcine reproductive and respiratory syndrome viruses. PBMCs, PRRSV
21  2018 MAVS induces a host cell defense to inhibit CSFV infection. CSFV, MAVS, RLRs, ROS
22  2018 Multiple antiviral approaches of (-)-epigallocatechin-3-gallate (EGCG) against porcine reproductive and respiratory syndrome virus infection in vitro. EGCG, PRRSV
23  2018 Porcine alveolar macrophage CD163 abundance is a pivotal switch for porcine reproductive and respiratory syndrome virus infection. iPAMs, PRRSV, SRCR1
24  2018 Porcine reproductive and respiratory syndrome virus nsp1beta and nsp11 antagonize the antiviral activity of cholesterol-25-hydroxylase via lysosomal degradation. IFN, ISG, NSP, PRRSV
25  2018 Porcine reproductive and respiratory syndrome virus suppresses post-transcriptionally the protein expression of IFN-beta by upregulating cellular microRNAs in porcine alveolar macrophages in vitro. HP, IFN, miRNA, PRRSV
26  2018 Swine Influenza Virus Induces RIPK1/DRP1-Mediated Interleukin-1 Beta Production. Drp1, NLRP3, RIPK1, ROS, SIV
27  2018 The effect of rfaD and rfaF of Haemophilus parasuis on lipooligosaccharide induced inflammation by NF-kappaB/MAPKs signaling in porcine alveolar macrophages. LOS
28  2018 Transcriptome Analysis Reveals Dynamic Gene Expression Profiles in Porcine Alveolar Macrophages in Response to the Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus. lncRNAs, PRRSV, PTGS2
29  2018 Transcriptome of porcine alveolar macrophages activated by interferon-gamma and lipopolysaccharide. IFN-gamma, LPS, PRRSV
30  2018 Tumor Necrosis Factor Receptor-Associated Factor 5 Interacts with the NS3 Protein and Promotes Classical Swine Fever Virus Replication. CSFV, MAPK, NS3, TRAF5
31  2017 Brucella Downregulates Tumor Necrosis Factor-alpha to Promote Intracellular Survival via Omp25 Regulation of Different MicroRNAs in Porcine and Murine Macrophages. UTR, WT
32  2017 Carbon Monoxide Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by the Cyclic GMP/Protein Kinase G and NF-kappaB Signaling Pathway. CO, HO-1, PRRSV
33  2017 Cholesterol exacerbates Mycoplasma hyopneumoniae-induced apoptosis via stimulating proliferation and adhesion to porcine alveolar macrophages. Mhyo, NO
34  2017 Curcumin is a promising inhibitor of genotype 2 porcine reproductive and respiratory syndrome virus infection. PRRSV
35  2017 Generation of murine macrophage-derived cell lines expressing porcine CD163 that support porcine reproductive and respiratory syndrome virus infection. p.i, pCD163, PRRSV
36  2017 Genome-wide analysis of long noncoding RNA profiling in PRRSV-infected PAM cells by RNA sequencing. GO, KEGG, lncRNA, PRRS, PRRSV
37  2017 Invitro immune toxicity of ochratoxin A in porcine alveolar macrophages: A role for the ROS-relative TLR4/MyD88 signaling pathway. OTA
38  2017 lgtF effects of Haemophilus parasuis LOS induced inflammation through regulation of NF-kappaB and MAPKs signaling pathways. IL-1 alpha, LOS, TNF-alpha
39  2017 MicroRNA expression profiling in alveolar macrophages of indigenous Chinese Tongcheng pigs infected with PRRSV in vivo. DE-miRNAs, PRRS, PRRSV, TC
40  2017 Overexpression of Histone Deacetylase 6 Enhances Resistance to Porcine Reproductive and Respiratory Syndrome Virus in Pigs. HDAC6, HP-PRRSV, NTG, PRRSV, Tg
41  2017 Porcine alveolar macrophage polarization is involved in inhibition of porcine reproductive and respiratory syndrome virus (PRRSV) replication. PRRSV
42  2017 Porcine circovirus type 2 increases interleukin-1beta and interleukin-10 production via the MyD88-NF-kappa B signaling pathway in porcine alveolar macrophages in vitro. IL-1beta, NF-kappaB, PCV2, TLR
43  2017 Proteomic Analysis of the Secretome of Porcine Alveolar Macrophages Infected with Porcine Reproductive and Respiratory Syndrome Virus. PRRS, PRRSV
44  2017 Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus. GM, hCD163L1, KO, PRRSV, SRCR
45  2017 Secondary Haemophilus parasuis infection enhances highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection-mediated inflammatory responses. HP-PRRSV, HPS
46  2017 The activation of the IFNbeta induction/signaling pathway in porcine alveolar macrophages by porcine reproductive and respiratory syndrome virus is variable. IFN-beta, ISG, PRRSV
47  2017 The integrity of PRRSV nucleocapsid protein is necessary for up-regulation of optimal interleukin-10 through NF-kappaB and p38 MAPK pathways in porcine alveolar macrophages. PRRS, PRRSV
48  2017 Transcriptome Differences in Porcine Alveolar Macrophages from Tongcheng and Large White Pigs in Response to Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection. DEGs, LW, PRRSV, TC
49  2016 Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release. A. pleuropneumoniae, TAA
50  2016 Classical swine fever virus NS5A protein changed inflammatory cytokine secretion in porcine alveolar macrophages by inhibiting the NF-kappaB signaling pathway. CSF, CSFV, NS
51  2016 Combining laboratory and mathematical models to infer mechanisms underlying kinetic changes in macrophage susceptibility to an RNA virus. PRRSV
52  2016 Influence of the amino acid residues at 70 in M protein of porcine reproductive and respiratory syndrome virus on viral neutralization susceptibility to the serum antibody. aa, HP-PRRSV, NA, NAbs, PRRSV
53  2016 Involvement of NF-kappaB in regulation of Actinobacillus pleuropneumoniae exotoxin ApxI-induced proinflammatory cytokine production in porcine alveolar macrophages. IL, JNK, MAPKs, NF, TNF
54  2016 MicroRNA let-7f-5p Inhibits Porcine Reproductive and Respiratory Syndrome Virus by Targeting MYH9. HP-PRRSV, miRNAs, MYH9, PRRSV
55  2016 MicroRNA-like viral small RNA from porcine reproductive and respiratory syndrome virus negatively regulates viral replication by targeting the viral nonstructural protein 2. MFE, miRNAs, nsp2, PRRSV, vsRNAs
56  2016 miRNA29 Promotes Viral Replication During Early Stage of PRRSV Infection In Vitro. PRRSV, RT-qPCR
57  2016 Porcine circovirus type 2 activates PI3K/Akt and p38 MAPK pathways to promote interleukin-10 production in macrophages via Cap interaction of gC1qR. IL, PCV2, PCVAD
58  2016 Quantitative estimation of the replication kinetics of genotype 2 PRRSV strains with different levels of virulence in vitro. HP-PRRSV, PRRSV, RT-qPCR
59  2016 Synthetic Toll-like receptor 7 ligand inhibits porcine reproductive and respiratory syndrome virus infection in primary porcine alveolar macrophages. ISGs, PRR, PRRSV, TLR7
60  2015 DRACO inhibits porcine reproductive and respiratory syndrome virus replication in vitro. dsRNA, IFIT3, PRRSV
61  2015 Haemophilus parasuis: infection, immunity and enrofloxacin. ---
62  2015 HP-PRRSV is attenuated by de-optimization of codon pair bias in its RNA-dependent RNA polymerase nsp9 gene. CPB, HP-PRRSV
63  2015 Immune response of porcine alveolar macrophages to a concurrent infection with porcine reproductive and respiratory syndrome virus and Haemophilus parasuis in vitro. PRRSV, ROS
64  2015 Inhibition of porcine reproductive and respiratory syndrome virus replication with exosome-transferred artificial microRNA targeting the 3' untranslated region. amiRNA, PRRS, rAd, RNAi, UTR
65  2015 Inhibitory activity and molecular mechanism of protegrin-1 against porcine reproductive and respiratory syndrome virus in vitro. PG-1, PRRSV
66  2015 Involvement of CD16 in antibody-dependent enhancement of porcine reproductive and respiratory syndrome virus infection. ADE, FcgammaR, PRRSV
67  2015 LSM14A inhibits porcine reproductive and respiratory syndrome virus (PRRSV) replication by activating IFN-beta signaling pathway in Marc-145. PRRSV
68  2015 Molecular characterization of the porcine S100A6 gene and analysis of its expression in pigs infected with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV). HP-PRRSV, PDTC, qPCR, RT-PCR
69  2015 Sasa quelpaertensis Nakai extract suppresses porcine reproductive and respiratory syndrome virus replication and modulates virus-induced cytokine production. PRRSV, SQE
70  2015 The effects of H3N2 swine influenza virus infection on TLRs and RLRs signaling pathways in porcine alveolar macrophages. MOI, RLRs, SIV, TLRs
71  2015 The Endoribonuclease Activity Essential for the Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus to Inhibit NLRP3 Inflammasome-Mediated IL-1beta Induction. IL-1beta, LPS, NSP, PRRSV
72  2014 Heme oxygenase-1 acts as an antiviral factor for porcine reproductive and respiratory syndrome virus infection and over-expression inhibits virus replication in vitro. HO-1, PRRSV
73  2014 Identification of differentially expressed proteins in porcine alveolar macrophages infected with virulent/attenuated strains of porcine reproductive and respiratory syndrome virus. HP-PRRSV, HSPB1, PKM2, PSMA6
74  2014 In vitro and ex vivo analyses of co-infections with swine influenza and porcine reproductive and respiratory syndrome viruses. IFN, PCLS, PRRSV, SIV
75  2014 Inhibition of porcine reproductive and respiratory syndrome virus infection by recombinant adenovirus- and/or exosome-delivered the artificial microRNAs targeting sialoadhesin and CD163 receptors. amiRNA, PRRS, PRRSV, rAds, Sn
76  2014 Modulation of CD163 expression by metalloprotease ADAM17 regulates porcine reproductive and respiratory syndrome virus entry. ADAM, PRRSV
77  2014 Porcine reproductive and respiratory syndrome virus nonstructural protein 4 antagonizes beta interferon expression by targeting the NF-kappaB essential modulator. BMo, IFNs, NEMO, NSP4, PRRSV
78  2014 Preparation of North American type II PRRSV infectious clone expressing green fluorescent protein. BHK-21, GFP, PRRSV, PRRSV-GFP
79  2014 RNA-sequence analysis of primary alveolar macrophages after in vitro infection with porcine reproductive and respiratory syndrome virus strains of differing virulence. IRF, PRRS, PRRSV, TSS
80  2013 Characterization of the microRNAome in porcine reproductive and respiratory syndrome virus infected macrophages. hpi, miRNA, PRRS, PRRSV
81  2013 Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-kappaB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages. CSF, CSFV, ELISA, IFN-beta, IL-1beta, IPS-1, IRF, MDA5, NF-kappaB, RIG-I
82  2013 Comparative expression of Toll-like receptors and inflammatory cytokines in pigs infected with different virulent porcine reproductive and respiratory syndrome virus isolates. PBMCs, PRRSV
83  2013 Control of the PI3K/Akt pathway by porcine reproductive and respiratory syndrome virus. CPE, HP-PRRSV, PI3K
84  2013 Induction of STAT1 phosphorylation at serine 727 and expression of proinflammatory cytokines by porcine reproductive and respiratory syndrome virus. IL-1beta, MAPK, MTA, nsp12, PRRSV, STAT1
85  2013 MicroRNA 181 suppresses porcine reproductive and respiratory syndrome virus (PRRSV) infection by targeting PRRSV receptor CD163. miR-181, PRRSV, UTR
86  2013 Molecular characterization of porcine SARM1 and its role in regulating TLRs signaling during highly pathogenic porcine reproductive and respiratory syndrome virus infection in vivo. HP-PRRSV, PRRs, qPCR, TLRs
87  2013 Molecular characterization, expression profiles, and association analysis with hematologic parameters of the porcine HPSE and HPSE2 genes. Hct, Hgb, HPSE2, HS, HSPGs, PRRSV, RBC, SNP, WBC
88  2013 Porcine reproductive and respiratory syndrome virus infection activates IL-10 production through NF-kappaB and p38 MAPK pathways in porcine alveolar macrophages. IL-10, MAPK, MyD88, PRRSV, RLR, TLR
89  2013 Reactomes of porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virus. DE, PRRS, SAGE, SOM
90  2013 Suppression of NK cell-mediated cytotoxicity against PRRSV-infected porcine alveolar macrophages in vitro. NK, PRV
91  2013 Transcription analysis of the porcine alveolar macrophage response to porcine circovirus type 2. ELISA, HPI, IFA, PCV2, PMWS, qPCR, TLR
92  2012 Cytokine production in immortalized porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virus. PRRSV
93  2012 Induction of interleukin-10 is dependent on p38 mitogen-activated protein kinase pathway in macrophages infected with porcine reproductive and respiratory syndrome virus. BMDMs, GP5, IL-10, MAPK, MDMs, PRRSV, STAT3
94  2012 Porcine reproductive and respiratory syndrome virus induces interleukin-15 through the NF-kappaB signaling pathway. BMo, DCs, IL-15, pIL-15, PRRSV
95  2012 Transcription analysis on response of porcine alveolar macrophages to Haemophilus parasuis. DE, H. parasuis, LPS, S100A4, S100A6
96  2011 Increase of CD163 but not sialoadhesin on cultured peripheral blood monocytes is coordinated with enhanced susceptibility to porcine reproductive and respiratory syndrome virus infection. BMo, PoSn, PRRSV
97  2011 Marked differences between MARC-145 cells and swine alveolar macrophages in IFNbeta-induced activation of antiviral state against PRRSV. 2AP, PKR, rswIFNbeta
98  2011 Mechanisms underlying Actinobacillus pleuropneumoniae exotoxin ApxI induced expression of IL-1beta, IL-8 and TNF-alpha in porcine alveolar macrophages. A. pleuropneumoniae, JNK, MAPKs
99  2011 Mitogen-activated protein kinases p38 and JNK mediate Actinobacillus pleuropneumoniae exotoxin ApxI-induced apoptosis in porcine alveolar macrophages. Apx
100  2011 Molecular characterization of transcriptome-wide interactions between highly pathogenic porcine reproductive and respiratory syndrome virus and porcine alveolar macrophages in vivo. HP-PRRSV, PRRS, PRRSV