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Abbreviation : PCP
Long Form : peptidyl carrier protein
No. Year Title Co-occurring Abbreviation
2019 Dipeptide synthesis by internal adenylation domains of a multidomain enzyme involved in nonribosomal peptide synthesis. Gly-Cys, NRPS, Thr-Cys
2019 The l-Alanosine Gene Cluster Encodes a Pathway for Diazeniumdiolate Biosynthesis. l-Dap
2018 NRPS Protein MarQ Catalyzes Flexible Adenylation and Specific S-Methylation. DAP, Me-Cys, MT, NRPS
2018 Ubiquitin-Mimicking Peptides Transfer Differentiates by E1 and E2 Enzymes. UBLs
2017 Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis. GPAs
2017 Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis. CAR, SAXS
2017 X-Ray Crystallography and Electron Microscopy of Cross- and Multi-Module Nonribosomal Peptide Synthetase Proteins Reveal a Flexible Architecture. MLP, NRPS
2016 Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. ---
2016 Generating Functional Recombinant NRPS Enzymes in the Laboratory Setting via Peptidyl Carrier Protein Engineering. NRPSs, TE
10  2016 Measurement of Nonribosomal Peptide Synthetase Adenylation Domain Activity Using a Continuous Hydroxylamine Release Assay. MesG, NRPS
11  2016 New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis. NRPSs
12  2015 Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis. NRPS
13  2015 Specific disulfide cross-linking to constrict the mobile carrier domain of nonribosomal peptide synthetases. ---
14  2015 Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL. NRPS
15  2015 X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis. GPAs, NRPS
16  2014 Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases. NRPSs
17  2014 Chemoenzymatic exchange of phosphopantetheine on protein and peptide. ACP
18  2014 The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase. NRPS
19  2013 An Sfp-type PPTase and associated polyketide and nonribosomal peptide synthases in Agrobacterium vitis are essential for induction of tobacco hypersensitive response and grape necrosis. ACP, HR, NRPS, PKS, PPTase
20  2013 Cytochrome p450sky interacts directly with the nonribosomal peptide synthetase to generate three amino acid precursors in skyllamycin biosynthesis. NRPS
21  2013 Unconventional origin and hybrid system for construction of pyrrolopyrrole moiety in kosinostatin biosynthesis. KST, PKS
22  2010 Functional dissection of surfactin synthetase initiation module reveals insights into the mechanism of lipoinitiation. ---
23  2010 Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases. ACP, NRPSs, PKSs, TE
24  2010 Molecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases. NADPH, nr, NRPSs, R domain, SDR, TE, VR
25  2009 Chapter 19. In vitro studies of phenol coupling enzymes involved in vancomycin biosynthesis. ---
26  2009 Structural insights into nonribosomal peptide enzymatic assembly lines. C-A-PCP-TE, TE
27  2008 Cu-free cycloaddition for identifying catalytic active adenylation domains of nonribosomal peptide synthetases by phage display. NRPS
28  2008 Exploring the substrate specificity of OxyB, a phenol coupling P450 enzyme involved in vancomycin biosynthesis. ---
29  2007 Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140. Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanine. NRPSs
30  2007 Oxidative phenol coupling reactions catalyzed by OxyB: a cytochrome P450 from the vancomycin producing organism. implications for vancomycin biosynthesis. NRPS
31  2007 Structural and functional insights into a peptide bond-forming bidomain from a nonribosomal peptide synthetase. ---
32  2007 The lyngbyatoxin biosynthetic assembly line: chain release by four-electron reduction of a dipeptidyl thioester to the corresponding alcohol. NADPH, NRPSs
33  2006 Characterization of a nonspecific phosphopantetheinyl transferase from Pseudomonas syringae pv. syringae FF5. CPs, PPTases, pspT
34  2006 Conformational switches modulate protein interactions in peptide antibiotic synthetases. ---
35  2006 Site-specific protein labeling by Sfp phosphopantetheinyl transferase. ---
36  2005 Characterization of the formation of the pyrrole moiety during clorobiocin and coumermycin A1 biosynthesis. ---
37  2005 Single-cell FRET imaging of transferrin receptor trafficking dynamics by Sfp-catalyzed, site-specific protein labeling. TfR1
38  2005 Synthesis of linear gramicidin requires the cooperation of two independent reductases. NRPSs
39  2005 Thioesterase portability and peptidyl carrier protein swapping in yersiniabactin synthetase from Yersinia pestis. NRPSs, PKSs, TE, Ybt
40  2005 Utility of epimerization domains for the redesign of nonribosomal peptide synthetases. NRPSs
41  2004 A nonribosomal peptide synthetase with a novel domain organization is essential for siderophore biosynthesis in Vibrio anguillarum. NRPS
42  2004 Identification and characterization of the pswP gene required for the parallel production of prodigiosin and serrawettin W1 in Serratia marcescens. NRPSs, ORF, PPTase
43  2004 Labeling proteins with small molecules by site-specific posttranslational modification. ---
44  2004 Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein-protein recognition. AcpSs, CoA, CPs, PPTases
45  2004 Phagemid encoded small molecules for high throughput screening of chemical libraries. bp, CoA
46  2003 Domain structure characterization of the multifunctional alpha-aminoadipate reductase from Penicillium chrysogenum by limited proteolysis. Activation of alpha-aminoadipate does not require the peptidyl carrier protein box or the reduction domain. alpha-AAR
47  2003 Loading peptidyl-coenzyme A onto peptidyl carrier proteins: a novel approach in characterizing macrocyclization by thioesterase domains. SNAC
48  2002 Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis. ---
49  2001 Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI. beta-OH-Tyr, ORFs
50  2000 Control of directionality in nonribosomal peptide synthesis: role of the condensation domain in preventing misinitiation and timing of epimerization. NRPS, TE
51  2000 Selectivity of the yersiniabactin synthetase adenylation domain in the two-step process of amino acid activation and transfer to a holo-carrier protein domain. cat, P-pant, Ybt
52  2000 Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases. ACPs, NRPSs
53  2000 The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates. NRPS
54  1999 Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily. CoA
55  1999 Crystallization and preliminary crystallographic studies of Sfp: a phosphopantetheinyl transferase of modular peptide synthetases. ---
56  1999 Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003. NRPSs, PPTases
57  1998 Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases. ACP, ArCP, CoA, PPTases, SrfABC
58  1998 Stoichiometry and specificity of in vitro phosphopantetheinylation and aminoacylation of the valine-activating module of surfactin synthetase. PPTase
59  1996 Biochemical characterization of peptidyl carrier protein (PCP), the thiolation domain of multifunctional peptide synthetases. ---