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Abbreviation : PERK
Long Form : pancreatic endoplasmic reticulum kinase
No. Year Title Co-occurring Abbreviation
2019 ER stress differentially affects pro-inflammatory changes induced by mitochondrial dysfunction in the human monocytic leukemia cell line, THP-1. ER, ETC, IRE1alpha, MD
2019 Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis. EAE, MS
2018 The unfolded protein response mediated by PERK is casually related to the pathogenesis of intervertebral disc degeneration. ATF4, ER, IL-6, IVD, NF, TNF-alpha, UPR
2016 Decursin enhances TRAIL-induced apoptosis through oxidative stress mediated- endoplasmic reticulum stress signalling in non-small cell lung cancers. ATF4, DR5, NSCLC, ROS, TRAIL
2016 PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis. GCPs
2015 Endoplasmic Reticulum Stress and Ethanol Neurotoxicity. AD, ALS, ATF6, CNS, ER, FASD, HD, IRE1, PD, UPR
2015 Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor A. ER, VEGF-A, VEGFR2
2015 Type I interferons mediate pancreatic toxicities of PERK inhibition. IFN, UPR
2014 Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice. eIF2B, VWMD
10  2014 PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases. EAE, MS
11  2013 Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. EAE, ER
12  2013 Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner. AMPK, ER, UPR
13  2012 Interferon-gamma activates nuclear factor-kappa B in oligodendrocytes through a process mediated by the unfolded protein response. CNS, IFN-gamma, NF-kappaB, UPR
14  2010 Structural determinants of PERK inhibitor potency and selectivity. UPR
15  2008 Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival. ER
16  2007 The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage. EAE, ISR, MS
17  2004 Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2. ---